Medizinische Universität Graz - Research portal
Wagner Martin |
** = Publications listed in SCI/SSCI/Pubmed
2024
Full paper/article (Journal)
** Liu, L; Zhou, S; Zaufel, A; Xie, Z; Racedo, S; Wagner, M; Zollner, G; Fickert, P; Zhang, Q
Bile acids regulate SF-1 to alter cholesterol balance in adrenocortical cells via S1PR2.
Biochem Biophys Res Commun. 2024; 692:149342
Doi: 10.1016/j.bbrc.2023.149342
Web of Science
PubMed
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Review
** Madreiter-Sokolowski, CT; Hiden, U; Krstic, J; Panzitt, K; Wagner, M; Enzinger, C; Khalil, M; Abdellatif, M; Malle, E; Madl, T; Osto, E; Schosserer, M; Binder, CJ; Olschewski, A
Targeting organ-specific mitochondrial dysfunction to improve biological aging.
Pharmacol Ther. 2024; 262:108710
Doi: 10.1016/j.pharmthera.2024.108710
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2023
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** Dean, AE; Jungwirth, E; Panzitt, K; Wagner, M; Anakk, S
Hepatic farnesoid X receptor is necessary to facilitate ductular reaction and expression of heme biosynthetic genes.
Hepatol Commun. 2023; 7(10):
Doi: 10.1097/HC9.0000000000000213
[OPEN ACCESS]
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2022
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** Douschan, P; Kovacs, G; Sassmann, T; Stadlbauer, V; Avian, A; Foris, V; Tatscher, E; Durchschein, F; Rainer, F; Spindelboeck, W; Wagner, M; Kniepeiss, D; Zollner, G; Bachmaier, G; Fickert, P; Olschewski, H; Stauber, RE
Pulmonary vascular disease and exercise hemodynamics in chronic liver disease.
Respir Med. 2022; 202:106987
Doi: 10.1016/j.rmed.2022.106987
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** Meinel, K; Szabo, D; Dezsofi, A; Pohl, S; Strini, T; Greimel, T; Aguiriano-Moser, V; Haidl, H; Wagner, M; Schlagenhauf, A; Jahnel, J
The Covert Surge: Murine Bile Acid Levels Are Associated With Pruritus in Pediatric Autoimmune Sclerosing Cholangitis.
Front Pediatr. 2022; 10: 903360
Doi: 10.3389/fped.2022.903360
[OPEN ACCESS]
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Review
** Panzitt, K; Zollner, G; Marschall, HU; Wagner, M
Recent advances on FXR-targeting therapeutics
MOL CELL ENDOCRINOL. 2022; 552: 111678
Doi: 10.1016/j.mce.2022.111678
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Abstract (Journal)
** Wagner, M; Jungwirth, E; Panzitt, K; Moore, D; Madl, T; Thallinger, G; Marschall, HU
FXR binding and transcription in the liver is signficantly altered in obese patients with NAFLD
J HEPATOL. 2022; 77: S696-S697.-European Association for the Studies of the Liver - EASL; Jun 22-25, 2022; London, Great Britain.
[Poster]
Web of Science
2021
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** Greimel, T; Jahnel, J; Pohl, S; Strini, T; Tischitz, M; Meier-Allard, N; Holasek, S; Meinel, K; Aguiriano-Moser, V; Zobel, J; Haidl, H; Gallistl, S; Panzitt, K; Wagner, M; Schlagenhauf, A
Bile acid-induced tissue factor activity in hepatocytes correlates with activation of farnesoid X receptor.
Lab Invest. 2021; 101(10):1394-1402
Doi: 10.1038/s41374-021-00628-z
[OPEN ACCESS]
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** Jungwirth, E; Panzitt, K; Marschall, HU; Thallinger, GG; Wagner, M
Meta-analysis and Consolidation of Farnesoid X Receptor Chromatin Immunoprecipitation Sequencing Data Across Different Species and Conditions
HEPATOL COMMUN. 2021;
Doi: 10.1002/hep4.1749
[OPEN ACCESS]
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Review
** Panzitt, K; Fickert, P; Wagner, M
Regulation of autophagy by bile acids and in cholestasis - CholestoPHAGY or CholeSTOPagy.
Biochim Biophys Acta Mol Basis Dis. 2021; 1867(2):166017-166017
Doi: 10.1016/j.bbadis.2020.166017
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** Panzitt, K; Wagner, M
FXR in liver physiology: Multiple faces to regulate liver metabolism
BBA-MOL BASIS DIS. 2021; 1867(7): 166133
Doi: 10.1016/j.bbadis.2021.166133
[OPEN ACCESS]
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Abstract (Journal)
** Leitner, M; Wagner, M; Jahnel, J
Alpha1-Antitrypsin deficiency and liver injury at the Medical University of Graz
WIEN KLIN WOCHENSCHR. 2021; 133(SUPPL 5):180-180.
[Poster]
Web of Science
2020
Full paper/article (Journal)
** Choi, S; Dong, B; Lin, CJ; Heo, MJ; Kim, KH; Sun, Z; Wagner, M; Putluri, N; Suh, JM; Wang, MC; Moore, DD
Methyl-Sensing Nuclear Receptor Liver Receptor Homolog-1 Regulates Mitochondrial Function in Mouse Hepatocytes.
Hepatology. 2020; 71(3):1055-1069
Doi: 10.1002/hep.30884
[OPEN ACCESS]
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** Panzitt, K; Jungwirth, E; Krones, E; Lee, JM; Pollheimer, M; Thallinger, GG; Kolb-Lenz, D; Xiao, R; Thorell, A; Trauner, M; Fickert, P; Marschall, HU; Moore, DD; Wagner, M
FXR-dependent Rubicon induction impairs autophagy in models of human cholestasis.
J Hepatol. 2020; 72(6):1122-1131
Doi: 10.1016/j.jhep.2020.01.014
[OPEN ACCESS]
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Review
** Wagner, M; Fickert, P
Drug Therapies for Chronic Cholestatic Liver Diseases.
Annu Rev Pharmacol Toxicol. 2020; 60(1):503-527
Doi: 10.1146/annurev-pharmtox-010818-021059
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Abstract (Journal)
** Munda, P; Aigner, E; Ferlitsch, A; Gschwantler, M; Hofer, H; Maieron, A; Peck-Radosavljevic, M; Stadlbauer-Kollner, V; Wagner, M
Diagnosis and Risk Stratification of non-alcoholic Steatohepatitis (NASH) - a Recommendation from Austrian Hepatologists.
WIEN KLIN WOCHENSCHR. 2020; 132(SUPPL 2):78-78.-ÖGGH Jahrestagung; ÖGGH Wien.
[Oral Communication]
Web of Science
2019
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** Al-Dury, S; Wahlström, A; Panzitt, K; Thorell, A; Ståhlman, M; Trauner, M; Fickert, P; Bäckhed, F; Fändriks, L; Wagner, M; Marschall, HU
Obeticholic acid may increase the risk of gallstone formation in susceptible patients.
J Hepatol. 2019; 71(5):986-991
Doi: 10.1016/j.jhep.2019.06.011
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** Liu, L; Panzitt, K; Racedo, S; Wagner, M; Platzer, W; Zaufel, A; Theiler-Schwetz, V; Obermayer-Pietsch, B; Müller, H; Höfler, G; Heinemann, A; Zollner, G; Fickert, P
Bile acids increase steroidogenesis in cholemic mice and induce cortisol secretion in adrenocortical H295R cells via S1PR2, ERK and SF-1.
Liver Int. 2019; 39(11):2112-2123
Doi: 10.1111/liv.14052
[OPEN ACCESS]
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Editorial
** Fickert, P; Wagner, M
Preface - Animal models in liver disease.
Biochim Biophys Acta Mol Basis Dis. 2019; 1865(5):867-868
Doi: 10.1016/j.bbadis.2019.02.004
[OPEN ACCESS]
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2018
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** Durchschein, F; Krones, E; Pollheimer, MJ; Zollner, G; Wagner, M; Raufman, JP; Fickert, P
Genetic loss of the muscarinic M3 receptor markedly alters bile formation and cholestatic liver injury in mice.
Hepatol Res. 2018; 48(3):E68-E77
Doi: 10.1111/hepr.12928
[OPEN ACCESS]
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** Fabian, E; Auer, H; Kump, P; Krause, R; Wagner, M; Fuchsjäger, M; Janek, E; Olschewski, H; Krejs, GJ
Clinical-Pathological Conference Series from the Medical University of Graz : Case No 168: A 28-year-old Syrian refugee with severe abdominal pain and eosinophilia.
Wien Klin Wochenschr. 2018; 130(19-20):581-588
Doi: 10.1007/s00508-018-1395-z
[OPEN ACCESS]
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** Kump, P; Wurm, P; Gröchenig, HP; Wenzl, H; Petritsch, W; Halwachs, B; Wagner, M; Stadlbauer, V; Eherer, A; Hoffmann, KM; Deutschmann, A; Reicht, G; Reiter, L; Slawitsch, P; Gorkiewicz, G; Högenauer, C
The taxonomic composition of the donor intestinal microbiota is a major factor influencing the efficacy of faecal microbiota transplantation in therapy refractory ulcerative colitis.
Aliment Pharmacol Ther. 2018; 47(1):67-77
Doi: 10.1111/apt.14387
[OPEN ACCESS]
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** Song, P; Zechner, C; Hernandez, G; Cánovas, J; Xie, Y; Sondhi, V; Wagner, M; Stadlbauer, V; Horvath, A; Leber, B; Hu, MC; Moe, OW; Mangelsdorf, DJ; Kliewer, SA
The Hormone FGF21 Stimulates Water Drinking in Response to Ketogenic Diet and Alcohol.
Cell Metab. 2018; 27(6):1338-1347
Doi: 10.1016/j.cmet.2018.04.001
[OPEN ACCESS]
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Abstract (Journal)
** Al-Dury, S; Wahlstrom, A; Katrin, P; Anders, T; Stahlman, M; Olsson, L; Trauner, M; Fickert, P; Moore, D; Backhed, F; Fandriks, L; Wagner, M; Marschall, HU
FXR agonist obeticholic acid increases gallbladder FGF19 in gallstone patients
J HEPATOL. 2018; 68: S449-S449.-International Liver Congress (ILC); APR 11-15, 2018; Paris, FRANCE.
Doi: 10.1016/S0168-8278(18)31140-1
[Oral Communication]
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** Al-Dury, S; Wahlstrom, A; Panzitt, K; Thorell, A; Stahlman, M; Trauner, MH; Fickert, P; Backhed, F; Fandriks, L; Wagner, M; Marschall, HU
Obeticholic Acid Increases Cholesterol Saturation and FGF19 in Human Gallbladder Bile
HEPATOLOGY. 2018; 68: 159A-159A.-Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting; NOV 09-13, 2018; San Francisco, CA.
[Oral Communication]
Web of Science
Comment
** Wagner, M; Fickert, P
Time for the dawn of multimodal therapies and the dusk for mono-therapeutic trials for cholestatic liver diseases?
Liver Int. 2018; 38(6):991-994
Doi: 10.1111/liv.13744
[OPEN ACCESS]
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2017
Review
** Fickert, P; Wagner, M
Biliary bile acids in hepatobiliary injury - What is the link?
J Hepatol. 2017; 67(3):619-631
Doi: 10.1016/j.jhep.2017.04.026
[OPEN ACCESS]
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Abstract (Journal)
** Douschan, P; Kovacs, G; Stadlbauer, V; Kniepeiss, D; Krones, E; Durchschein, F; Rainer, F; Spindelboeck, W; Wagner, M; Zollner, G; Avian, A; Fickert, P; Olschewski, A; Olschewski, H; Stauber, RE
Exercise capacity and exercise hemodynamics in the screening for pulmonary vascular disease (PVD) in patients with portal hypertension - results from a prospective cross-sectional study
J HEPATOL. 2017; 66(1):S568-S569.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS.
Doi: 10.1016/S0168-8278(17)31556-8
[Poster]
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2016
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** Wagner, M; Choi, S; Panzitt, K; Mamrosh, JL; Lee, JM; Zaufel, A; Xiao, R; Wooton-Kee, R; Ståhlman, M; Newgard, CB; Borén, J; Moore, DD
Liver receptor homolog-1 is a critical determinant of methyl-pool metabolism.
Hepatology. 2016; 63(1):95-106
Doi: 10.1002/hep.28124
[OPEN ACCESS]
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Review
** Wagner, M; Trauner, M
Recent advances in understanding and managing cholestasis.
F1000Res. 2016; 5(8):
Doi: 10.12688/f1000research.8012.1
[OPEN ACCESS]
PubMed
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Editorial
** Krones, E; Wagner, M
Fibroblast growth factor 19 meets mammalian target of rapamycin: A mitogenic Tête-à-Tête under consideration.
Hepatology. 2016; 64(4):1028-1030
Doi: 10.1002/hep.28691
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** Wagner, M; Fickert, P; Zollner, G
Secretin and cholestasis, two sides of a coin.
Hepatology. 2016; 64(3):714-716
Doi: 10.1002/hep.28687
[OPEN ACCESS]
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Abstract (Journal)
** Grande, P; Horvath, A; Wagner, M; Stadlbauer, V
FGF21 and its connection to alcohol consumption
WIEN KLIN WOCHENSCHR. 2016; 128: S384-S384.
[Poster]
Web of Science
** Krones, E; Bork, T; Grahammer, F; Wagner, M; Rosenkranz, AR; Huber, TB; Fickert, P
ACCUMULATION OF LC3 II IN CHOLEMIC NEPHROPATHY IS CAUSED BY BLOCKAGE OF AUTOPHAGIC FLUX
NEPHROL DIAL TRANSPL. 2016; 31: 103-104.-53rd ERA-EDTA Congress; MAY 21-24, 2016; Vienna, AUSTRIA.
[Poster]
Web of Science
** Panzitt, K; Marschall, HU; Moore, DD; Trauner, MH; Fickert, P; Wagner, M
The autophagy inhibitor Rubicon is a direct target of the bile acid receptor FXR in human liver and is induced in human cholestasis
HEPATOLOGY. 2016; 63(1 SUPP):159A-159A.-67th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 11-15, 2016; Boston, MA.
[Poster]
Web of Science
** Schuller, M; Wagner, M; Panzitt, K
Endogenous phosphatidylcholine generation via the PEMT pathway modulates LRH-1 signaling - Dietary clues for treating NAFLD?
WIEN KLIN WOCHENSCHR. 2016; 128: S383-S384.
[Poster]
Web of Science
2015
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** Hartig, SM; Bader, DA; Abadie, KV; Motamed, M; Hamilton, MP; Long, W; York, B; Mueller, M; Wagner, M; Trauner, M; Chan, L; Bajaj, M; Moore, DD; Mancini, MA; McGuire, SE
Ubc9 Impairs Activation of the Brown Fat Energy Metabolism Program in Human White Adipocytes.
Mol Endocrinol. 2015; 29(9):1320-1333
Doi: 10.1210/me.2015-1084
[OPEN ACCESS]
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** Wooton-Kee, CR; Jain, AK; Wagner, M; Grusak, MA; Finegold, MJ; Lutsenko, S; Moore, DD
Elevated copper impairs hepatic nuclear receptor function in Wilson's disease.
J Clin Invest. 2015; 125(9):3449-3460
Doi: 10.1172/JCI78991
[OPEN ACCESS]
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Review
** Krones, E; Wagner, M; Eller, K; Rosenkranz, AR; Trauner, M; Fickert, P
Bile acid-induced cholemic nephropathy.
Dig Dis. 2015; 33(3):367-375
Doi: 10.1159/000371689
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Abstract (Journal)
** Panzitt, K; Marschall, HU; Trauner, M; Fickert, P; Wagner, M
Effects of Ursodeoxycholic-acid and Rifampicin on autophagy in the liver
HEPATOLOGY. . 2015; 62: 538A-538A.-66th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 13-17, 2015; San Francisco, CA.
[Oral Communication]
Web of Science
2014
Full paper/article (Journal)
** Lee, JM; Wagner, M; Xiao, R; Kim, KH; Feng, D; Lazar, MA; Moore, DD
Nutrient-sensing nuclear receptors coordinate autophagy.
Nature. 2014; 516(7529): 112-115.
Doi: 10.1038/nature13961
[OPEN ACCESS]
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** Mamrosh, JL; Lee, JM; Wagner, M; Stambrook, PJ; Whitby, RJ; Sifers, RN; Wu, SP; Tsai, MJ; Demayo, FJ; Moore, DD
Nuclear receptor LRH-1/NR5A2 is required and targetable for liver endoplasmic reticulum stress resolution.
Elife. 2014; 3(6):e01694-e01694
Doi: 10.7554/eLife.01694
[OPEN ACCESS]
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Abstract (Journal)
** Zaufel, A; Wagner, M; Krones, E; Fickert, P; Zollner, G
Cholestasis and Bile Acids start the Adrenocortical Function, Salzburg, 25th-27th September, 2014
WIEN KLIN WOCHENSCHR. 2014; 126(17-18):570-571.
[Poster]
Web of Science
2013
Abstract (Journal)
** Mueller, M; Marschall, HU; Claudel, T; Wagner, M; Fickert, P; Lackner, C; Einarsson, C; Thorell, A; Trauner, M
URSODEOXYCHOLIC ACID COUNTERACTS LIPOTOXICITY AND INDUCES UNFOLDED PROTEIN RESPONSE IN MORBIDLY OBESE PATIENTS
J HEPATOL. . 2013; 58: S517-S517.-International Liver Congress / 48th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 24-28, 2013; Amsterdam, NETHERLANDS.
Doi: 10.1016/S0168-8278(13)61279-9
[Poster]
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2012
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Silbert, D; Gustafsson, U; Sahlin, S; Trauner, M
Combined rifampicin and ursodeoxycholic acid treatment does not amplify rifampicin effects on hepatic detoxification and transport systems in humans.
Digestion. 2012; 86(3):244-249
Doi: 10.1159/000341420
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Abstract (Journal)
** Marschall, HU; Mueller, M; Wagner, M; Fickert, P; Zollner, G; Silbert, D; Lackner, C; Thorell, A; Trauner, M
HIGH LEVELS OF URSODEOXYCHOLIC ACID ACT AS FXR ANTAGONIST AND DEPLETE LIVER CHOLESTEROL DUE TO INCREASED BILE ACID SYNTHESIS IN MORBIDLY OBESE PATIENTS
J HEPATOL. . 2012; 56: S515-S515.-47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 18-22, 2012; Barcelona, SPAIN.
Doi: 10.1016/S0168-8278(12)61319-1
[Poster]
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** Wagner, M; Wooton-Kee, CR; Mamrosh, JL; Lee, JM; Xiao, R; Vareed, SK; Sreekumar, A; Moore, DD
LRH-1 is a key regulator of carbon one metabolism and its loss protects from liver injury in the methionine-choline deficient NASH model
HEPATOLOGY. 2012; 56: 866A-867A.-63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 09-13, 2012; Boston, MA.
Web of Science
2011
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Lackner, C; Thorell, A; Trauner, M
Ursodeoxycholic acid for treatment of fatty liver disease and dyslipidemia in morbidly obese patients.
Dig Dis. 2011; 29(1):117-118
Doi: 10.1159/000324146
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Review
** Claudel, T; Zollner, G; Wagner, M; Trauner, M
Role of nuclear receptors for bile acid metabolism, bile secretion, cholestasis, and gallstone disease.
Biochim Biophys Acta. 2011; 1812(8):867-878
Doi: 10.1016/j.bbadis.2010.12.021
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** Wagner, M; Moore, DD
Endoplasmic reticulum stress and glucose homeostasis.
Curr Opin Clin Nutr Metab Care. 2011; 14(4):367-373
Doi: 10.1097/MCO.0b013e32834778d4
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** Wagner, M; Zollner, G; Trauner, M
Nuclear receptors in liver disease.
HEPATOLOGY. 2011; 53(3): 1023-1034.
Doi: 10.1002/hep.24148
[OPEN ACCESS]
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2010
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** Stojakovic, T; Claudel, T; Putz-Bankuti, C; Fauler, G; Scharnagl, H; Wagner, M; Sourij, H; Stauber, RE; Winkler, K; März, W; Wascher, TC; Trauner, M
Low-dose atorvastatin improves dyslipidemia and vascular function in patients with primary biliary cirrhosis after one year of treatment.
Atherosclerosis. 2010; 209(1): 178-183.
Doi: 10.1016/j.atherosclerosis.2009.08.052
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Review
** Trauner, M; Arrese, M; Wagner, M
Fatty liver and lipotoxicity.
Biochim Biophys Acta. 2010; 1801(3): 299-310.
Doi: 10.1016/j.bbalip.2009.10.007
[OPEN ACCESS]
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** Trauner, M; Claudel, T; Fickert, P; Moustafa, T; Wagner, M
Bile acids as regulators of hepatic lipid and glucose metabolism.
Dig Dis. 2010; 28(1):220-224
Doi: 10.1159/000282091
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** Trauner, M; Fickert, P; Baghdasaryan, A; Claudel, T; Halilbasic, E; Moustafa, T; Wagner, M; Zollner, G
New insights into autoimmune cholangitis through animal models.
Dig Dis. 2010; 28(1):99-104
Doi: 10.1159/000282072
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** Wagner, M; Zollner, G; Trauner, M
Nuclear receptor regulation of the adaptive response of bile acid transporters in cholestasis.
SEMIN LIVER DIS. 2010; 30(2): 160-177.
Doi: 10.1055/s-0030-1253225
[OPEN ACCESS]
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** Zollner, G; Wagner, M; Trauner, M
Nuclear receptors as drug targets in cholestasis and drug-induced hepatotoxicity.
Pharmacol Ther. 2010; 126(3):228-243
Doi: 10.1016/j.pharmthera.2010.03.005
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Abstract (Journal)
** Mader, JK; Bock, G; Wagner, M; Forrer, F; Lackner, C; Portugaller, RH; Fickert, P; Krejs, GJ; Pieber, TR
Recurrent hypoglycemia in adults - a diagnostic challenge (case report).
WIEN KLIN WOCHENSCHR. 2010; 122(17-18):A7-A7.-ÖGIM; Sep 29-Oct. 1; Salzburg, Austria.
[Poster]
Web of Science
** Stojakovic, T; Claudel, T; Putz-Bankuti, C; Fauler, G; Scharnagl, H; Wagner, M; Sourij, H; Stauber, RE; Winkler, K; Marz, W; Wascher, TC; Trauner, M
LOW-DOSE ATORVASTATIN IMPROVES DYSLIPIDEMIA AND VASCULAR FUNCTION IN PATIENTS WITH PRIMARY BILIARY CIRRHOSIS AFTER ONE YEAR OF TREATMENT.
J HEPATOL. 2010; 52: S431-S432.-45th Annual Meeting of the European Association for the Study of the Liver (EASL); APR 14-18, 2010; Vienna, AUSTRIA.
Doi: 10.1016/S0168-8278(10)61118-X
[Poster]
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2009
Full paper/article (Journal)
** Fickert, P; Fuchsbichler, A; Moustafa, T; Wagner, M; Zollner, G; Halilbasic, E; Stöger, U; Arrese, M; Pizarro, M; Solís, N; Carrasco, G; Caligiuri, A; Sombetzki, M; Reisinger, E; Tsybrovskyy, O; Zatloukal, K; Denk, H; Jaeschke, H; Pinzani, M; Trauner, M
Farnesoid X receptor critically determines the fibrotic response in mice but is expressed to a low extent in human hepatic stellate cells and periductal myofibroblasts.
Am J Pathol. 2009; 175(6):2392-2405
Doi: 10.2353/ajpath.2009.090114
[OPEN ACCESS]
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** Fickert, P; Fuchsbichler, A; Wagner, M; Silbert, D; Zatloukal, K; Denk, H; Trauner, M
The role of the hepatocyte cytokeratin network in bile formation and resistance to bile acid challenge and cholestasis in mice.
Hepatology. 2009; 50(3):893-899
Doi: 10.1002/hep.23068
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** Klein, K; Kullak-Ublick, GA; Wagner, M; Trauner, M; Eloranta, JJ
Hepatocyte nuclear factor-4alpha and bile acids regulate human concentrative nucleoside transporter-1 gene expression.
Am J Physiol Gastrointest Liver Physiol. 2009; 296(4): G936-G947.
Doi: 10.1152/ajpgi.90678.2008
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** Sturm, E; Wagner, M; Trauner, M
Nuclear receptor ligands in therapy of cholestatic liver disease.
Front Biosci. 2009; 14(6):4299-4325
Doi: 10.2741/3529
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** Wagner, M; Zollner, G; Trauner, M
New molecular insights into the mechanisms of cholestasis.
J Hepatol. 2009; 51(3): 565-580.
Doi: 10.1016/j.jhep.2009.05.012
[OPEN ACCESS]
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** Klein, K; Eloranta, JJ; Wagner, M; Trauner, M; Kullak-Ublick, GA
Regulation of human concentrative nucleoside transporter-1 gene expression
NAUNYN-SCHMIED ARCH PHARMACOL. 2009; 379: 490-
[Oral Communication]
Web of Science
** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Lundasen, T; Gustafsson, U; Sahlin, S; Trauner, M
STIMULATION OF HEPATOBILIARY DETOXIFICATION AND TRANSPORT SYSTEMS IN HUMAN LIVER BY COMBINED TREATMENT WITH RIFAMPICIN AND URSODEOXYCHOLIC ACID
J HEPATOL. 2009; 50: 675-Vienna, Austria.
Doi: 10.1016/S0168-8278(09)60677-2
[Poster]
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** Stojakovic, T; Putz-Bankuti, C; Fauler, G; Scharnagl, M; Wagner, M; Sourij, H; Stauber, RE; Marz, W; Wascher, TC; Trauner, M
Low-dose atorvastatin improves dyslipidemia and vascular function in patients with primary biliary cirrhosis after one year of treatment
WIEN KLIN WOCHENSCHR. 2009; 121(15-16):A26-A26.-40.Jahrestagung der Österreichischen Gesellschaft für Innere Medizin (ÖGIM); SEP 17-19, 2009; Vienna, AUSTRIA.
[Poster]
Web of Science
2008
Comment
** Wagner, M; Zollner, G; Trauner, M
Ischemia and cholestasis: more than (just) the bile ducts!
Transplantation. 2008; 85(8):1083-1085
Doi: 10.1097/TP.0b013e31816b2393
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** Wagner, M; Zollner, G; Trauner, M
Nuclear bile acid receptor farnesoid X receptor meets nuclear factor-kappaB: new insights into hepatic inflammation.
Hepatology. 2008; 48(5):1383-1386
Doi: 10.1002/hep.22668
[OPEN ACCESS]
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2007
Full paper/article (Journal)
** Stojakovic, T; Putz-Bankuti, C; Fauler, G; Scharnagl, H; Wagner, M; Stadlbauer, V; Gurakuqi, G; Stauber, RE; März, W; Trauner, M
Atorvastatin in patients with primary biliary cirrhosis and incomplete biochemical response to ursodeoxycholic acid.
Hepatology. 2007; 46(3):776-784
Doi: 10.1002/hep.21741
[OPEN ACCESS]
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** Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Gujral, JS; Zatloukal, K; Denk, H; Jaeschke, H; Trauner, M
Hepatobiliary transporter expression in intercellular adhesion molecule 1 knockout and Fas receptor-deficient mice after common bile duct ligation is independent of the degree of inflammation and oxidative stress.
Drug Metab Dispos. 2007; 35(9):1694-1699
Doi: 10.1124/dmd.107.015610
[OPEN ACCESS]
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** Zollner, G; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Zatloukal, K; Denk, H; Trauner, M
Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis.
Liver Int. 2007; 27(7):920-929
Doi: 10.1111/j.1478-3231.2007.01506.x
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Review
** Geier, A; Wagner, M; Dietrich, CG; Trauner, M
Principles of hepatic organic anion transporter regulation during cholestasis, inflammation and liver regeneration.
Biochim Biophys Acta. 2007; 1773(3): 283-308.
Doi: 10.1016/j.bbamcr.2006.04.014
[OPEN ACCESS]
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** Marschall, HU; Wagner, M; Zollner, G; Trauner, M
Clinical hepatotoxicity. Regulation and treatment with inducers of transport and cofactors.
MOL PHARM. 2007; 4(6): 895-910.
Doi: 10.1021/mp060133c
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** Trauner, M; Fickert, P; Wagner, M
MDR3 (ABCB4) defects: a paradigm for the genetics of adult cholestatic syndromes.
Semin Liver Dis. 2007; 27(1):77-98
Doi: 10.1055/s-2006-960172
[OPEN ACCESS]
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Abstract (Journal)
** Jahnel, J; Wagner, M; Langner, C; Hoegenauer, C; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Denk, H; Trauner, M
Impact of colitis on bile secretion and hepatobiliary transporter expression in mice possible implications for pathogenesis of sclerosing cholangitis
J HEPATOL. 2007; 46: S122-S122.
Doi: 10.1016/S0168-8278(07)61907-2
[Poster]
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** Wagner, M; Moustafa, T; Fickert, P; Zollner, G; Gumhold, J; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M
Absence of FXR protects mice from bile-infarcts in biliary obstruction by reduction of bile acid-independent bile flow: Implications for targeting FXR in treatment of cholestasis?
J HEPATOL. 2007; 46: S5-S5.-42th Annual Meeting, European Association for the Study of the Liver; April, 11-15, 2007; Barcelona, Spain.
Doi: 10.1016/S0168-8278(07)61603-1
[Oral Communication]
Web of Science
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** Zollner, G; Caligiuri, A; Fickert, P; Wagner, M; Silbert, D; Pinzani, M; Trauner, M
Expression of bile acid transport and detoxification systems and their regulatory nuclear receptors in human hepatic stellate cells
J HEPATOL. 2007; 46: S135-S135.-42th Annual Meeting, European Association for the Study of the Liver ; April 11-15, 2007; Barcelona, Spain.
Doi: 10.1016/S0168-8278(07)61944-8
[Poster]
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2006
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** Ellis, E; Wagner, M; Lammert, F; Nemeth, A; Gumhold, J; Strassburg, CP; Kylander, C; Katsika, D; Trauner, M; Einarsson, C; Marschall, HU
Successful treatment of severe unconjugated hyperbilirubinemia via induction of UGT1A1 by rifampicin.
J HEPATOL. 2006; 44(1): 243-245.
Doi: 10.1016/j.jhep.2005.09.011
(- Case Report)
Web of Science
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** Fickert, P; Fuchsbichler, A; Marschall, HU; Wagner, M; Zollner, G; Krause, R; Zatloukal, K; Jaeschke, H; Denk, H; Trauner, M
Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice.
Am J Pathol. 2006; 168(2):410-422
Doi: 10.2353/ajpath.2006.050404
[OPEN ACCESS]
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** Fickert, P; Wagner, M; Marschall, HU; Fuchsbichler, A; Zollner, G; Tsybrovskyy, O; Zatloukal, K; Liu, J; Waalkes, MP; Cover, C; Denk, H; Hofmann, AF; Jaeschke, H; Trauner, M
24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
Gastroenterology. 2006; 130(2):465-481
Doi: 10.1053/j.gastro.2005.10.018
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** Marschall, HU; Wagner, M; Bodin, K; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Sjövall, J; Trauner, M
Fxr(-/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids.
J Lipid Res. 2006; 47(3):582-592
Doi: 10.1194/jlr.M500427-JLR200
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** Zollner, G; Wagner, M; Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Halilbasic, E; Denk, H; Marschall, HU; Trauner, M
Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids.
Am J Physiol Gastrointest Liver Physiol. 2006; 290(5):G923-G932
Doi: 10.1152/ajpgi.00490.2005
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Review
** Zollner, G; Marschall, HU; Wagner, M; Trauner, M
Role of nuclear receptors in the adaptive response to bile acids and cholestasis: pathogenetic and therapeutic considerations.
Mol Pharm. 2006; 3(3): 231-251.
Doi: 10.1021/mp060010s
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** Moustafa, T; Fickert, P; Prokesch, A; Wagner, M; Fuchsbichler, A; Silbert, D; Gumhold, J; Denk, H; Trajanoski, Z; Trauner, M
Common bile-duct-ligation of FXR knockout mice results in severe hepatic steatosis due to enhancement in lipogenic gene expression
J HEPATOL. 44: S28-S28.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA.
Doi: 10.1016/S0168-8278(06)80063-2
[Poster]
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** Zollner, G; Wagner, M; Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Helmut, D; Marschall, HU; Trauner, M
Role of nuclear bile acid receptor FXR in regulation of bile acid detoxification and organic solute transporter (OST-alpha/beta) expression in bile acid-fed mice
J HEPATOL. 44: S124-S124.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA.
Doi: 10.1016/S0168-8278(06)80322-3
[Poster]
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2005
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** Fickert, P; Trauner, M; Fuchsbichler, A; Zollner, G; Wagner, M; Marschall, HU; Zatloukal, K; Denk, H
Oncosis represents the main type of cell death in mouse models of cholestasis.
J Hepatol. 2005; 42(3):378-385
Doi: 10.1016/j.jhep.2004.10.016
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** Geier, A; Zollner, G; Dietrich, CG; Wagner, M; Fickert, P; Denk, H; van Rooijen, N; Matern, S; Gartung, C; Trauner, M
Cytokine-independent repression of rodent Ntcp in obstructive cholestasis.
Hepatology. 2005; 41(3):470-477
Doi: 10.1002/hep.20594
[OPEN ACCESS]
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Diczfalusy, U; Gumhold, J; Silbert, D; Fuchsbichler, A; Benthin, L; Grundström, R; Gustafsson, U; Sahlin, S; Einarsson, C; Trauner, M
Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in humans.
Gastroenterology. 2005; 129(2):476-485
Doi: 10.1016/j.gastro.2005.05.009
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** Wagner, M; Halilbasic, E; Marschall, HU; Zollner, G; Fickert, P; Langner, C; Zatloukal, K; Denk, H; Trauner, M
CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice.
Hepatology. 2005; 42(2):420-430
Doi: 10.1002/hep.20784
[OPEN ACCESS]
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** Zollner, G; Wagner, M; Fickert, P; Geier, A; Fuchsbichler, A; Silbert, D; Gumhold, J; Zatloukal, K; Kaser, A; Tilg, H; Denk, H; Trauner, M
Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver.
Am J Physiol Gastrointest Liver Physiol. 2005; 289(5):G798-G805
Doi: 10.1152/ajpgi.00319.2004
[OPEN ACCESS]
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** Zollner, G; Wagner, M; Fickert, P; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M
Hepatobiliary transporter expression in human hepatocellular carcinoma.
Liver Int. 2005; 25(2):367-379
Doi: 10.1111/j.1478-3231.2005.01033.x
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Review
** Trauner, M; Wagner, M; Fickert, P; Zollner, G
Molecular regulation of hepatobiliary transport systems: clinical implications for understanding and treating cholestasis.
J Clin Gastroenterol. 2005; 39(4 Suppl 2):S111-S124
Doi: 10.1097/01.mcg.0000155551.37266.26
[OPEN ACCESS]
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** Wagner, M; Trauner, M
Transcriptional regulation of hepatobiliary transport systems in health and disease: implications for a rationale approach to the treatment of intrahepatic cholestasis.
Ann Hepatol. 2005; 4(2): 77-99.
Doi: 10.1016/S1665-2681(19)32071-X
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Abstract (Journal)
** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Krause, R; Zatloukal, K; Marschall, HU; Jaeschke, H; Denk, H; Trauner, M
Lithocholic acid feeding induces biliary obstruction and destructive cholangitis in mice
J HEPATOL. 2005; 42: 113-113.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
Web of Science
** Fickert, P; Wagner, M; Marshall, HU; Fuchsbichler, A; Zollner, G; Zatloukal, K; Liu, J; Waalkes, MP; Cover, C; Denk, H; Hofmann, AF; Jaeschke, H; Trauner, M
24-norursodeoxycholic acid as novel therapeutic approach to sclerosing cholangitis in Mdr2 (ABCB4) knockout mice
HEPATOLOGY. 2005; 42: -56th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; NOV 11-15, 2005; San Francisco, CA.
Web of Science
** Geier, A; Zollner, G; Dietrich, CG; Wagner, M; Fickert, P; Denk, H; van Rooijen, N; Matern, S; Gartung, C; Trauner, M
Cytokine-independent repression of rodent Ntcp in obstructive cholestasis
J HEPATOL. 2005; 42: 114-114.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
Web of Science
** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundstrom, R; Gustafsson, U; Sahlin, S; Einarsson, C; Trauner, M
Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in human liver
GASTROENTEROLOGY. 2005; 128: A755-A755.
Web of Science
** Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Gujral, J; Zatloukal, K; Jaeschke, H; Deck, H; Trauner, M
Role of inflammation for hepatobiliary transporter expression in ICAM-/- and lpr mice after common bile duct ligation
GASTROENTEROLOGY. 2005; 128: A89-A89.
Web of Science
** Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Gujral, JS; Zatloukal, K; Denk, H; Jaeschke, H; Trauner, M
Alterations of hepatobiliary transporter expression in response to common bile duct ligation in mice are independent of ICAM-1 and FAS-receptor expression
J HEPATOL. 2005; 42: 115-115.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
Web of Science
** Zollner, G; Wagner, M; Fickert, P; Gumhold, J; Silbert, D; Marschall, HU; Denk, H; Trauner, M
Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis
GASTROENTEROLOGY. 2005; 128: A691-A691.
Web of Science
** Zollner, G; Wagner, M; Fickert, P; Gumhold, J; Silbert, D; Marschall, HU; Denk, H; Trauner, M
Expression of key bile acid detoxification enzymes and the alternative bile acid export pump MRP4 in primary biliary cirrhosis
J HEPATOL. 2005; 42: 240-240.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
Web of Science
2004
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** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Kaser, A; Tilg, H; Krause, R; Lammert, F; Langner, C; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M
Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
Gastroenterology. 2004; 127(1):261-274
Doi: 10.1053/j.gastro.2004.04.009
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** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Kaser, A; Tilg, H; Krause, R; Langner, C; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M
Bile acids regurgitation from leaky bile ducts causes sclerosing cholangitis in Mdr2 knockout mice
GASTROENTEROLOGY. 2004; 126: A663-A663.
Web of Science
** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Kaser, A; Tilg, H; Krause, R; Langner, C; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M
Biliary leakage of fluorescent bile acids in MDR2 knockout mice: Evidence for a critical role of bile duct leakage in the pathogenesis of sclerosing cholangitis
J HEPATOL. 2004; 40: 91-91.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(04)90295-4
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** Fickert, P; Trauner, M; Fuchsbichler, A; Zollner, G; Wagner, M; Marschall, HU; Zartloukal, K; Denk, H; Zsengeller, Z; Szabo, C
Oncosis represents the main type of cell death in mouse models of cholestasis: evidence for a critical role of poly(ADP-ribose) polymerase (PARP) activation in bile acid-induced hepatocytes death
FASEB J. 2004; 18: A558-A558.-Experimental Biology 2004 Meeting; APR 17-21, 2004; Washington, DC.
Web of Science
** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundstrom, R; Sahlin, S; Einarsson, C; Trauner, M
Comprehensive study of the effects of rifampicin and ursodeoxycholic acid on genes and proteins involved in regulation, transport and detoxification of biliary compounds in gallstone patients
GASTROENTEROLOGY. 2004; 126: A746-A746.
Web of Science
** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumholdt, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundstrom, R; Sahlin, S; Einarsson, C; Trauner, M
Comprehensive study of the effects of rifampicin and ursodeoxycholic acid on genes and proteins involved in regulation, transport and detoxification of biliary compounds in gallstone patients
J HEPATOL. 2004; 40: 93-93.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(04)90303-0
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** Wagner, M; Fickert, P; Marschall, HU; Zollner, G; Silbert, D; Fuchsbichler, A; Gumhold, J; Schuetz, JD; Gonzalez, FJ; Zatloukal, K; Denk, H; Trauner, M
Alternative exretory routes for accumulating bile acids via adaptive renal ABC transporter expression in common bile duct-ligated (CBDL) mice
GASTROENTEROLOGY. 2004; 126: A129-A130.
Web of Science
** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Gu, GL; Marschall, HU; Denk, H; Trauner, M
Role of adaptive hepatobiliary transporter expression and regulation of bile acid synthetic enzymes in MDR2-/- mice: A model for chronic cholestatic liver disease due to sclerosing cholangitis
J HEPATOL. 2004; 40: 163-163.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(04)90557-0
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** Wagner, M; Fickert, P; Zollner, G; Silbert, D; Fuchsbichler, A; Gumhold, J; Schuetz, JD; Gonzalez, FJ; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M
Adaptive renal ABC transporter expression in common bile duct-ligated mice
J HEPATOL. 2004; 40: 26-26.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(04)90073-6
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** Wagner, M; Fickert, P; Zollner, G; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M
Hepatic and renal ABC transporter expression in mice depends on gender and changes in pregnancy
GASTROENTEROLOGY. 2004; 126: A130-A130.
Web of Science
** Wagner, M; Fickert, P; Zollner, G; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M
Gender and pregnancy affect hepatic and renal ABC transporter expression in mice
J HEPATOL. 2004; 40: 94-94.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(04)90307-8
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** Wagner, M; Halilbasic, E; Fickert, P; Zollner, G; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Denk, H; Trauner, M
Nuclear receptor (PXR, CAR) agonists induce adaptive hepatic transporter and enzyme expression in mouse liver
J HEPATOL. 2004; 40: 25-25.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(04)90069-4
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** Wagner, M; Halilbasic, E; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M
Xenobiotic nuclear receptor (PXR, CAR) agonists coordinately stimulate a spectrum of detoxification enzymes and transport systems involved in the adaptive response to cholestasis in vivo.
HEPATOLOGY. 2004; 40: 489A-489A.-55th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); OCT 29-NOV 02, 2004; Boston, MA.
Web of Science
** Zollner, G; Halilbasic, E; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M
Cholic acid (CA) and ursodeoxycholic acid (UDCA) exert different effects on hepatic and renal expression of Mrp4 and Mrp6, two novel ABC transporters
GASTROENTEROLOGY. 2004; 126: A16-A16.
Web of Science
** Zollner, G; Halilbasic, E; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M
Differential effects of ursodeoxycholic acid (UDCA) and cholic acid (CA) on hepatic and renal expression of MRP4 and MRP6, two novel abc transporters, in mice
J HEPATOL. 2004; 40: 25-25.
Doi: 10.1016/S0168-8278(04)90070-0
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** Zollner, G; Wagner, M; Fickert, P; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Guo, GL; Marschall, HU; Denk, H; Trauner, M
Mdr2(-/-) mice with sclerosing cholangitis: A model of chronic cholestasis to study the role of the adaptive response of hepatobiliary transport systems and bile acid synthetic enzymes
GASTROENTEROLOGY. 2004; 126: A751-A751.
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** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Silbert, D; Tsybrovskyy, O; Zatloukal, K; Guo, GL; Schuetz, JD; Gonzalez, FJ; Marschall, HU; Denk, H; Trauner, M
Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice.
Gastroenterology. 2003; 125(3):825-838
Doi: 10.1016/S0016-5085(03)01068-0
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** Wagner, M; Kaufmann, P; Fickert, P; Trauner, M; Lackner, C; Stauber, RE
Successful conservative management of acute hepatic failure following exertional heatstroke.
Eur J Gastroenterol Hepatol. 2003; 15(10):1135-1139
Doi: 10.1097/01.meg.0000085465.12407.32
(- Case Report)
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** Zollner, G; Fickert, P; Fuchsbichler, A; Silbert, D; Wagner, M; Arbeiter, S; Gonzalez, FJ; Marschall, HU; Zatloukal, K; Denk, H; Trauner, M
Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine.
J Hepatol. 2003; 39(4):480-488
Doi: 10.1016/S0168-8278(03)00228-9
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** Fickert, P; Trauner, M; Fuchsbichler, A; Zollner, G; Wagner, M; Zenz, R; Zsengeller, Z; Szabo, C; Denk, H
Inhibition of poly(ADP-ribose) polymerase (PARP) protects mice from cholestatic liver injury.
HEPATOLOGY 2003 38: 576A-576A.
Web of Science
** Wagner, M; Fickert, P; Fuchsbichler, A; Silbert, D; Gumhold, J; Zollner, G; Zatloukal, K; Marschall, HU; Schuetz, JD; Gonzalez, FJ; Denk, H; Trauner, M
Hepatic and renal ABC transporter expression as critical determinants of ursodeoxycholic acid-induced bile infarcts in bile duct-ligated mice.
HEPATOLOGY 2003 38: 688A-689A.
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** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Silbert, D; Marschall, HU; Gonzalez, FJ; Zatloukal, K; Denk, H; Trauner, M
The role of the bile acid receptor FXR in determining ATP-binding cassette (ABC) transporter expression and liver injury in common bile duct ligated (CBDL) mice
J HEPATOL 2003 38: 190-190.
Doi: 10.1016/S0168-8278(03)80031-4
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** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Silbert, D; Tsybrovskyy, O; Gonzalez, FJ; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M
Role of nuclear bile acid receptor, FXR, in determining ATP-binding cassette (ABC) transporter expression and cholestatic liver injury in common bile duct-ligated mice
GASTROENTEROLOGY 2003 124: A697-A698.
Doi: 10.1016/S0016-5085(03)83527-8
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Wagner, M; Guo, G; Gonzalez, FJ; Zatloukal, K; Denk, H; Trauner, M
Role of nuclear bile salt receptors Fxr and Pxr in mediating adaptive hepatobiliary transporter response to cholic acid (CA) in mouse liver
GASTROENTEROLOGY 2003 124: A59-A59.
Doi: 10.1016/S0016-5085(03)80292-5
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Wagner, M; Zatloukal, K; Denk, H; Trauner, M
Role of short heterodimer partner (SHP) -dependent and -independent pathways for regulation of Na+/taurocholate cotransporter (NTCP) expression in cholestatic mouse models.
J HEPATOL. 2003; 38(2):9-10.-38th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; MAR 29-APR 01, 2003; ISTANBUL, TURKEY.
Doi: 10.1016/S0168-8278(03)80442-7
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Wagner, M; Zatloukal, K; Denk, H; Trauner, M
Regulation of the Na+/taurocholate cotransporter Ntcp via short heterodimer partner (SHP)-dependent or SHP-independent mechanims depends on the type of cholestatic injury
GASTROENTEROLOGY 2003 124: A730-A730.
Doi: 10.1016/S0016-5085(03)83688-0
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** Zollner, G; Fickert, P; Wagner, M; Fuchsbichler, A; Silbert, D; Gumhold, J; Zatloukal, K; Denk, H; Trauner, M
Induction of intestinal multidrug resistance-associated proteins 2 and 3 (Mrp2, Mrp3) by cholic acid (CA) and ursodeoxycholic acid (UDCA) in mice.
HEPATOLOGY 2003 38: 689A-689A.
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