Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Obenauf Anna Christina |
** = Publikationen gelistet in SCI/SSCI/Pubmed
2023
Originalarbeit (Zeitschrift)
** Leiendecker, L; Neumann, T; Jung, PS; Cronin, SM; Steinacker, TL; Schleiffer, A; Schutzbier, M; Mechtler, K; Kervarrec, T; Laurent, E; Bachiri, K; Coyaud, E; Murali, R; Busam, KJ; Itzinger-Monshi, B; Kirnbauer, R; Cerroni, L; Calonje, E; Rutten, A; Stubenrauch, F; Griewank, KG; Wiesner, T; Obenauf, AC
Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell-like Program Conserved in HPV-Positive Cancers
CANCER DISCOV. 2023; 13(1): 70-84.
Doi: 10.1158/2159-8290.CD-22-0489
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2016
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** Mlecnik, B; Bindea, G; Angell, HK; Maby, P; Angelova, M; Tougeron, D; Church, SE; Lafontaine, L; Fischer, M; Fredriksen, T; Sasso, M; Bilocq, AM; Kirilovsky, A; Obenauf, AC; Hamieh, M; Berger, A; Bruneval, P; Tuech, JJ; Sabourin, JC; Le Pessot, F; Mauillon, J; Rafii, A; Laurent-Puig, P; Speicher, MR; Trajanoski, Z; Michel, P; Sesboüe, R; Frebourg, T; Pagès, F; Valge-Archer, V; Latouche, JB; Galon, J
Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability.
Immunity. 2016; 44(3):698-711
Doi: 10.1016/j.immuni.2016.02.025
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** Mlecnik, B; Bindea, G; Kirilovsky, A; Angell, HK; Obenauf, AC; Tosolini, M; Church, SE; Maby, P; Vasaturo, A; Angelova, M; Fredriksen, T; Mauger, S; Waldner, M; Berger, A; Speicher, MR; Pagès, F; Valge-Archer, V; Galon, J
The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis.
Sci Transl Med. 2016; 8(327):327ra26-327ra26
Doi: 10.1126/scitranslmed.aad6352
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2015
Originalarbeit (Zeitschrift)
** Obenauf, AC; Zou, Y; Ji, AL; Vanharanta, S; Shu, W; Shi, H; Kong, X; Bosenberg, MC; Wiesner, T; Rosen, N; Lo, RS; Massagué, J
Therapy-induced tumour secretomes promote resistance and tumour progression.
Nature. 2015; 520(7547): 368-372.
Doi: 10.1038/nature14336
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** Wiesner, T; Lee, W; Obenauf, AC; Ran, L; Murali, R; Zhang, QF; Wong, EW; Hu, W; Scott, SN; Shah, RH; Landa, I; Button, J; Lailler, N; Sboner, A; Gao, D; Murphy, DA; Cao, Z; Shukla, S; Hollmann, TJ; Wang, L; Borsu, L; Merghoub, T; Schwartz, GK; Postow, MA; Ariyan, CE; Fagin, JA; Zheng, D; Ladanyi, M; Busam, KJ; Berger, MF; Chen, Y; Chi, P
Alternative transcription initiation leads to expression of a novel ALK isoform in cancer.
Nature. 2015; 526(7573):453-457
Doi: 10.1038/nature15258
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2014
Originalarbeit (Zeitschrift)
** Mlecnik, B; Bindea, G; Angell, HK; Sasso, MS; Obenauf, AC; Fredriksen, T; Lafontaine, L; Bilocq, AM; Kirilovsky, A; Tosolini, M; Waldner, M; Berger, A; Fridman, WH; Rafii, A; Valge-Archer, V; Pagès, F; Speicher, MR; Galon, J
Functional network pipeline reveals genetic determinants associated with in situ lymphocyte proliferation and survival of cancer patients.
Sci Transl Med. 2014; 6(228):228ra37-228ra37
Doi: 10.1126/scitranslmed.3007240
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2013
Originalarbeit (Zeitschrift)
** Bindea, G; Mlecnik, B; Tosolini, M; Kirilovsky, A; Waldner, M; Obenauf, AC; Angell, H; Fredriksen, T; Lafontaine, L; Berger, A; Bruneval, P; Fridman, WH; Becker, C; Pagès, F; Speicher, MR; Trajanoski, Z; Galon, J
Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.
Immunity. 2013; 39(4):782-795
Doi: 10.1016/j.immuni.2013.10.003
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2012
Originalarbeit (Zeitschrift)
** Katz, SF; Lechel, A; Obenauf, AC; Begus-Nahrmann, Y; Kraus, JM; Hoffmann, EM; Duda, J; Eshraghi, P; Hartmann, D; Liss, B; Schirmacher, P; Kestler, HA; Speicher, MR; Rudolph, KL
Disruption of Trp53 in livers of mice induces formation of carcinomas with bilineal differentiation.
Gastroenterology. 2012; 142(5):1229-1239
Doi: 10.1053/j.gastro.2012.02.009
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** Mathiesen, RR; Fjelldal, R; Liestl, K; Due, EU; Geigl, JB; Riethdorf, S; Borgen, E; Rye, IH; Schneider, IJ; Obenauf, AC; Mauermann, O; Nilsen, G; Christian Lingjaerde, O; Brresen-Dale, AL; Pantel, K; Speicher, MR; Naume, B; Baumbusch, LO
High-resolution analyses of copy number changes in disseminated tumor cells of patients with breast cancer.
Int J Cancer. 2012; 131(4):E405-E415
Doi: 10.1002/ijc.26444
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Abstract (Zeitschrift)
** Wiesner, T; Obenauf, AC; Murali, R; Fried, I; Griewank, KG; Ulz, P; Windpassinger, C; Wackernagel, W; Loy, S; Wolf, I; Viale, A; Lash, AE; Pirun, M; Socci, ND; Rütten, A; Palmedo, G; Abramson, D; Offit, K; Ott, A; Becker, JC; Cerroni, L; Kutzner, H, Bastian, BC; Speicher, MR
Germline mutations in BAP1 predispose to melanocytic tumors.
Experimental Dermatology. 2012; 21(3):e22--39th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF); March 01-03, 2012; Marburg, Germany.
[Poster]
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2011
Originalarbeit (Zeitschrift)
** Wiesner, T; Obenauf, AC; Murali, R; Fried, I; Griewank, KG; Ulz, P; Windpassinger, C; Wackernagel, W; Loy, S; Wolf, I; Viale, A; Lash, AE; Pirun, M; Socci, ND; Rütten, A; Palmedo, G; Abramson, D; Offit, K; Ott, A; Becker, JC; Cerroni, L; Kutzner, H; Bastian, BC; Speicher, MR
Germline mutations in BAP1 predispose to melanocytic tumors.
Nat Genet. 2011; 43(10):1018-1021
Doi: 10.1038/ng.910
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2010
Originalarbeit (Zeitschrift)
** Obenauf, AC; Schwarzbraun, T; Auer, M; Hoffmann, EM; Waldispuehl-Geigl, J; Ulz, P; Günther, B; Duba, HC; Speicher, MR; Geigl, JB
Mapping of balanced chromosome translocation breakpoints to the basepair level from microdissected chromosomes.
J Cell Mol Med. 2010; 14(8):2078-2084
Doi: 10.1111/j.1582-4934.2010.01116.x
(- Case Report)
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** Roetzer, KM; Schwarzbraun, T; Obenauf, AC; Hauser, E; Speicher, MR
Further evidence for the pathogenicity of 15q24 microduplications distal to the minimal critical regions.
Am J Med Genet A. 2010; 152A(12):3173-3178
Doi: 10.1002/ajmg.a.33750
(- Case Report)
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** Schallmoser, K; Bartmann, C; Rohde, E; Bork, S; Guelly, C; Obenauf, AC; Reinisch, A; Horn, P; Ho, AD; Strunk, D; Wagner, W
Replicative senescence-associated gene expression changes in mesenchymal stromal cells are similar under different culture conditions.
Haematologica. 2010; 95(6): 867-874.
Doi: 10.3324/haematol.2009.011692
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** Van Raamsdonk, CD; Griewank, KG; Crosby, MB; Garrido, MC; Vemula, S; Wiesner, T; Obenauf, AC; Wackernagel, W; Green, G; Bouvier, N; Sozen, MM; Baimukanova, G; Roy, R; Heguy, A; Dolgalev, I; Khanin, R; Busam, K; Speicher, MR; O'Brien, J; Bastian, BC
Mutations in GNA11 in Uveal Melanoma.
N ENGL J MED. 2010; 363(23): 2191-2199.
Doi: 10.1056/NEJMoa1000584
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** Wiesner, T; Obenauf, AC; Cota, C; Fried, I; Speicher, MR; Cerroni, L
Alterations of the cell-cycle inhibitors p27(KIP1) and p16(INK4a) are frequent in blastic plasmacytoid dendritic cell neoplasms.
J Invest Dermatol. 2010; 130(4):1152-1157
Doi: 10.1038/jid.2009.369
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Abstract (Zeitschrift)
** Reinisch, A; Hofmann, N; Obenauf, A; Karl, K; Rohde, E; Schallmoser, K; Thaler, D; Fruhwirth, M; Flicker, K; Linkesch, W; Speicher, M; Strunk, D
STABLE VESSEL GENERATION TROUGH APPLICATION OF BLOOD-DERIVED ENDOTHELIAL COLONY FORMING PROGENITOR CELLS (ECFCS) AND MESENCHYMAL STROMAL/STEM CELLS (MSCS)
HAEMATOL-HEMATOL J. 15th Congress of the European Hematology Association. 2010; 95(s2):0509-220.-15th Congress of the European Hematology Association. ; JUN 10-13, 2010; Barcelona, SPAIN.
[Oral Communication]
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** Reinisch, A; Hofmann, NA; Obenauf, A; Kashofer, K; Rohde, E; Schallmoser, K; Thaler, D; Fruhwirth, M; Flicker, K; Linkesch, W; Speicher, M; Strunk, D
Sustained vessel formation through co-transplantation of endothelial colony-forming progenitor cells with mesenchymal stromal cells
BONE MARROW TRANSPLANT. 2010; 45: S52-S52. -36th Annual Meeting of the European Group for Blood and Marrow Transplantation; MAR 21-24, 2010; Vienna, AUSTRIA.
[Oral Communication]
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** Schallmoser, K; Bartmann, C; Rohde, E; Bork, S; Guelly, C; Obenauf, A; Reinisch, A; Horn, P; Ho, A; Linkesch, W; Lanzer, G; Wagner, W; Strunk, D
SENESCENCE-ASSOCIATED GENE EXPRESSION CHANGES IN MESENCHYMAL STROMAL/STEM CELLS
HAEMATOL-HEMATOL J. 2010; 95(s2):0249-110.-15th Congress of the European Hematology Association. ; JUN 10-13, 2010; Barcelona, SPAIN.
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** Schallmoser, K; Bartmann, C; Rohde, E; Bork, S; Guelly, C; Obenauf, AC; Reinisch, A; Hom, P; Ho, AD; Linkesch, W; Lanzer, G; Wagner, W; Strunk, D
Replicative senescence-associated gene expression changes in mesenchymal stromal cells
BONE MARROW TRANSPLANT. 2010; 45: S281-S281.
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** Schallmoser K; Bartmann, C; Rohde E; Bork, S; Guelly, C; Obenauf, AC; Reinisch, A; Horn, P; Ho, AD; Linkesch, W; Lanzer, G; Wagner, W; Strunk, D
Similarity of Replicative Senescence-Associated Gene Expression Changes in Mesenchymal Stromal Cells under Various Culture Conditions.
XXXIst International Congress of the ISBT in Joint Cooperation with the 43rd Congress of the DGTI2010; 99(1):481-482.-XXXIst International Congress of the ISBT in Joint Cooperation with the 43rd Congress of the DGTI; JUN 26-JUL 2, 2010; Berlin, GERMANY.
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** Schallmoser, K; Rohde, E; Obenauf, AC; Reinisch, A; Bartmann, C; Lanzer, G; Linkesch, W; Strunk, D
Genomic Stability of Mesenchymal Stromal/Stem Cells After Long-Term Culture
TRANSFUSION. 2010; 50: 24A-24A.-AABB; 08.-12.10.2010; Baltimore, MD, USA.
[Oral Communication]
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** Schallmoser, K; Rohde, E; Reinisch, A; Obenauf, A; Bartmann, C; Lanzer, G; Linkesch, W; Strunk, D
GENOMIC STABILITY IN LONG-TERM CULTURED MESENCHYMAL STROMAL/STEM CELLS
HAEMATOL-HEMATOL J. 2010; 95: 0247
[Poster]
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** Schallmoser, K; Rohde, E; Reinisch, A; Obenauf, AC; Bartmann, C; Lanzer, G; Linkesch, W; Strunk, D
Alteration of genomic stability in long-term cultured mesenchymal stromal cells
BONE MARROW TRANSPLANT. 2010; 45: S280-S280.-36th Annual Meeting of the European Group for Blood and Marrow Transplantation; MAR 21-24, 2010; Vienna, AUSTRIA.
[Poster]
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2009
Originalarbeit (Zeitschrift)
** Begus-Nahrmann, Y; Lechel, A; Obenauf, AC; Nalapareddy, K; Peit, E; Hoffmann, E; Schlaudraff, F; Liss, B; Schirmacher, P; Kestler, H; Danenberg, E; Barker, N; Clevers, H; Speicher, MR; Rudolph, KL
p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice.
Nat Genet. 2009; 41(10): 1138-1143.
Doi: 10.1038/ng.426
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** Geigl, JB; Obenauf, AC; Waldispuehl-Geigl, J; Hoffmann, EM; Auer, M; Hörmann, M; Fischer, M; Trajanoski, Z; Schenk, MA; Baumbusch, LO; Speicher, MR
Identification of small gains and losses in single cells after whole genome amplification on tiling oligo arrays.
Nucleic Acids Res. 2009; 37(15): e105-e105.
Doi: 10.1093/nar/gkp526
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** Liu, ZY; Obenauf, AC; Speicher, MR; Kopan, R
Rapid identification of homologous recombinants and determination of gene copy number with reference/query pyrosequencing (RQPS).
GENOME RES. 2009; 19(11): 2081-2089.
Doi: 10.1101/gr.093856.109
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** Pfragner, R; Behmel, A; Höger, H; Beham, A; Ingolic, E; Stelzer, I; Svejda, B; Moser, VA; Obenauf, AC; Siegl, V; Haas, O; Niederle, B
Establishment and characterization of three novel cell lines - P-STS, L-STS, H-STS - derived from a human metastatic midgut carcinoid.
ANTICANCER RES. 2009; 29(6): 1951-1961.
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** Reinisch, A; Hofmann, NA; Obenauf, AC; Kashofer, K; Rohde, E; Schallmoser, K; Flicker, K; Lanzer, G; Linkesch, W; Speicher, MR; Strunk, D
Humanized large-scale expanded endothelial colony-forming cells function in vitro and in vivo.
Blood. 2009; 113(26): 6716-6725.
Doi: 10.1182/blood-2008-09-181362
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Kurzbericht/Letter
** Schwarzbraun, T; Obenauf, A; Langmann, A; Gruber-Sedlmayr, U; Wagner, K; Speicher, M; Kroisel, P
Predictive diagnosis of the cancer prone Li-Fraumeni syndrome by accident: new challenges through whole genome array testing.
J Med Genet. 2009; 46(5): 341-344.
Doi: 10.1136/jmg.2008.064972
(- Case Report)
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** Wiesner, T; Obenauf, AC; Geigl, JB; Vallant, EM; Speicher, MR; Fink-Puches, R; Kerl, H; Cerroni, L
9p21 deletion in primary cutaneous large B-cell lymphoma, leg type, may escape detection by standard FISH assays.
J Invest Dermatol. 2009; 129(1): 238-240.
Doi: 10.1038/jid.2008.224
(- Case Report)
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Abstract (Zeitschrift)
** Pfragner, R; Hoeger, H; Behmel, A; Beham, A; Stelzer, I; Obenauf, AC; Haas, HS; Ingolic, E; Siegl, V; Aguiriano-Moser, V; Svejda, B; Haas, O; Niederle, B
In vitro- and in vivo-models of human neuroendocrine tumors: three novel transplantable cell lines from metastatic midgut carcinoid.
AMINO ACIDS. 2009; 37: 103-103.-11th International Congress on Amino Acids, Peptides and Proteins; AUG 3-7; Vienna.
[Oral Communication]
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** Reinisch, A; Hofmann, NA; Obenauf, A; Kashofer, K; Rohde, E; Schallmoser, K; Thaler, D; Fruehwirth, M; Flicker, K; Linkesch, W; Speicher, M; Strunk, D
Vascular regeneration by adult blood-derived endothelial colony-forming cells expanded under animal serum-free conditions
BONE MARROW TRANSPLANT. 35th Annual Meeting of the European Group for Blood and Marrow Transplantation2009; 43(1):S19-S20.-35th Annual Meeting of the European Group for Blood and Marrow Transplantation; MAR 29-APR 01, 2009; Goteborg, SWEDEN.
[Oral Communication]
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** Schallmoser, K; Rohde, E; Reinisch, A; Obenauf, A; Bartmann, C; Lanzer, G; Linkesch, W; Strunk, D
Evidence for genomic stability of bone marrow-derived MSCS after large-scale expansion in a humanised system.
BONE MARROW TRANSPLANT. 35th Annual Meeting of the European Group for Blood and Marrow Transplantation2009; 43(1):S187-S187.-35th Annual Meeting of the European Group for Blood and MarrowTransplantation; MAR 29-APR 01, 2009; Goteborg, SWEDEN.
[Poster]
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** Schwarzbraun, T; Wang, LHC; Obenauf, AC; Ulz, P; Nigg, EA; Speicher, MR
MITOSIS UPDATED - PICH AND THE ANAPHASE THREADS
CELL ONCOL. 2009; 31(2):90-91.-3rd Marie Curie-Genome Architecture in Relation to Disease Meeting (MC-GARD); APR 01-05, 2009; Edinburgh, SCOTLAND.
[Oral Communication]
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** Thomas, W; Obenauf, AC; Speicher, MR; Cerroni, L
Genomic characterisation of blastic plasmacytoid dendritic cell neoplasms by array CGH
J INVEST DERMATOL. JID2009; 129: S73-S73.-39th Annual Meeting of the ESDR; SEP 9-12, 2009; Budapest, HUNGARY.
[Poster]
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Originalarbeit (Konferenzband)
** Schallmoser, K; Rohde, E; Bartmann, C; Obenauf, AC; Reinisch, A; Strunk, D
Platelet-derived growth factors for GMP-compliant propagation of mesenchymal stromal cells.
Biomed Mater Eng. 2009; 19(4-5): 271-276.
Doi: 10.3233/BME-2009-0591
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2008
Originalarbeit (Zeitschrift)
** Schallmoser, K; Rohde, E; Reinisch, A; Bartmann, C; Thaler, D; Drexler, C; Obenauf, AC; Lanzer, G; Linkesch, W; Strunk, D
Rapid large-scale expansion of functional mesenchymal stem cells from unmanipulated bone marrow without animal serum.
Tissue Eng Part C Methods. 2008; 14(3): 185-196.
Doi: 10.1089/ten.tec.2008.0060
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Übersichtsarbeit
** Geigl, JB; Obenauf, AC; Schwarzbraun, T; Speicher, MR
Defining 'chromosomal instability'.
Trends Genet. 2008; 24(2): 64-69.
Doi: 10.1016/j.tig.2007.11.006
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Abstract (Zeitschrift)
** Reinisch, A; Hofmann, NA; Obenauf, A; Kashofer, K; Rohde, E; Schallmoser, K; Thaler, D; Fruehwirth, M; Linkesch, W; Speicher, M; Strunk, D
Making Functional Endothelial Progenitors: Humanized Large-scale Animal Serum-free Propagated Adult Blood-derived Endothelial Colony-forming Cells Assemble Stable Perfused Vessels In vivo.
Fiftieth Annual Meeting Abstracts2008; 112(11):659-659.-American Society of Hematology 50th Annual Meeting and Exposition; DEC 6-9, 2008; San Francisco, USA.
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** Schallmoser, K; Rohde, E; Reinisch, A; Obenauf, AC; Bartmann, C; Lanzer, G; Linkesch, W; Strunk, D
Genomic stability and safety of MSCs after animal serum-free humanized clinical scale propagation.
Fiftieth annual meeting abstracts2008; 112(11):805-805.-American Society of Hematology 50th Annual Meeting and Exposition; DEC 6-9, 2008; San Francisco, USA.
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Abstract (Konferenzband)
** Schallmoser, K; Rohde, E; Reinisch, A; Obenauf, A; Speicher, M; Bartmann, C; Lanzer, G; Linkesch, W; Strunk, D
Minimum requirements for fully humanised clinical scale propagation of multipotent mesenchymal stromal cells.
. 2008; 41(1): S314-S314.
[Poster]
Web of Science
2007
Abstract (Zeitschrift)
** Schwarzbraun, T; Pfleghaar, K; Obenauf, A; Cremer, T; Cremer, M; Speicher, M
The impact of CDC4 mutations and cyclin E increase on chromosomal instability
CELL ONCOL. 2007; 29(2):116-117.-MC-GARD Conference: Molecular profiling of the genome; Amsterdam, Netherlands.
[Oral Communication]
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