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Wiesner Thomas |

** = Publications listed in SCI/SSCI/Pubmed

2023

Full paper/article (Journal)

** Leiendecker, L; Neumann, T; Jung, PS; Cronin, SM; Steinacker, TL; Schleiffer, A; Schutzbier, M; Mechtler, K; Kervarrec, T; Laurent, E; Bachiri, K; Coyaud, E; Murali, R; Busam, KJ; Itzinger-Monshi, B; Kirnbauer, R; Cerroni, L; Calonje, E; Rutten, A; Stubenrauch, F; Griewank, KG; Wiesner, T; Obenauf, AC Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell-like Program Conserved in HPV-Positive Cancers
CANCER DISCOV. 2023; 13(1): 70-84. Doi: 10.1158/2159-8290.CD-22-0489 [OPEN ACCESS]
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2017

Full paper/article (Journal)

** Möller, I; Murali, R; Müller, H; Wiesner, T; Jackett, LA; Scholz, SL; Cosgarea, I; van de Nes, JA; Sucker, A; Hillen, U; Schilling, B; Paschen, A; Kutzner, H; Rütten, A; Böckers, M; Scolyer, RA; Schadendorf, D; Griewank, KG Activating cysteinyl leukotriene receptor 2 (CYSLTR2) mutations in blue nevi.
Mod Pathol. 2017; 30(3):350-356 Doi: 10.1038/modpathol.2016.201 [OPEN ACCESS]
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2016

Full paper/article (Journal)

** Busam, KJ; Vilain, RE; Lum, T; Busam, JA; Hollmann, TJ; Saw, RP; Coit, DC; Scolyer, RA; Wiesner, T Primary and Metastatic Cutaneous Melanomas Express ALK Through Alternative Transcriptional Initiation.
Am J Surg Pathol. 2016; 40(6):786-795 Doi: 10.1097/PAS.0000000000000611 [OPEN ACCESS]
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** Kiuru, M; Jungbluth, A; Kutzner, H; Wiesner, T; Busam, KJ Spitz Tumors: Comparison of Histological Features in Relationship to Immunohistochemical Staining for ALK and NTRK1.
Int J Surg Pathol. 2016; 24(3):200-206 Doi: 10.1177/1066896916630375
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Review

** Wiesner, T; Kutzner, H; Cerroni, L; Mihm, MC; Busam, KJ; Murali, R Genomic aberrations in spitzoid melanocytic tumours and their implications for diagnosis, prognosis and therapy.
Pathology. 2016; 48(2):113-131 Doi: 10.1016/j.pathol.2015.12.007 [OPEN ACCESS]
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Comment

** Wiesner, T Genomic Rearrangements in Unusual and Atypical Melanocytic Neoplasms.
JAMA Dermatol. 2016; 152(3):260-262 Doi: 10.1001/jamadermatol.2015.3501
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2015

Full paper/article (Journal)

** Murali, R; Chandramohan, R; Möller, I; Scholz, SL; Berger, M; Huberman, K; Viale, A; Pirun, M; Socci, ND; Bouvier, N; Bauer, S; Artl, M; Schilling, B; Schimming, T; Sucker, A; Schwindenhammer, B; Grabellus, F; Speicher, MR; Schaller, J; Hillen, U; Schadendorf, D; Mentzel, T; Cheng, DT; Wiesner, T; Griewank, KG Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway.
Oncotarget. 2015; 6(34):36041-36052 Doi: 10.18632/oncotarget.5936 [OPEN ACCESS]
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** Obenauf, AC; Zou, Y; Ji, AL; Vanharanta, S; Shu, W; Shi, H; Kong, X; Bosenberg, MC; Wiesner, T; Rosen, N; Lo, RS; Massagué, J Therapy-induced tumour secretomes promote resistance and tumour progression.
Nature. 2015; 520(7547): 368-372. Doi: 10.1038/nature14336 [OPEN ACCESS]
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** Shain, AH; Garrido, M; Botton, T; Talevich, E; Yeh, I; Sanborn, JZ; Chung, J; Wang, NJ; Kakavand, H; Mann, GJ; Thompson, JF; Wiesner, T; Roy, R; Olshen, AB; Gagnon, A; Gray, JW; Huh, N; Hur, JS; Busam, KJ; Scolyer, RA; Cho, RJ; Murali, R; Bastian, BC Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway.
Nat Genet. 2015; 47(10): 1194-1199. Doi: 10.1038/ng.3382 [OPEN ACCESS]
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** Wiesner, T; Kiuru, M; Scott, SN; Arcila, M; Halpern, AC; Hollmann, T; Berger, MF; Busam, KJ NF1 Mutations Are Common in Desmoplastic Melanoma.
Am J Surg Pathol. 2015; 39(10): 1357-1362. Doi: 10.1097/PAS.0000000000000451 [OPEN ACCESS]
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** Wiesner, T; Lee, W; Obenauf, AC; Ran, L; Murali, R; Zhang, QF; Wong, EW; Hu, W; Scott, SN; Shah, RH; Landa, I; Button, J; Lailler, N; Sboner, A; Gao, D; Murphy, DA; Cao, Z; Shukla, S; Hollmann, TJ; Wang, L; Borsu, L; Merghoub, T; Schwartz, GK; Postow, MA; Ariyan, CE; Fagin, JA; Zheng, D; Ladanyi, M; Busam, KJ; Berger, MF; Chen, Y; Chi, P Alternative transcription initiation leads to expression of a novel ALK isoform in cancer.
Nature. 2015; 526(7573):453-457 Doi: 10.1038/nature15258 [OPEN ACCESS]
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Review

** Wiesner, T; Kutzner, H Morphological and genetic aspects of Spitz tumors].
Pathologe. 2015; 36(1): 37-43. Doi: 10.1007/s00292-014-1984-1
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2014

Full paper/article (Journal)

** Busam, KJ; Kutzner, H; Cerroni, L; Wiesner, T Clinical and pathologic findings of Spitz nevi and atypical Spitz tumors with ALK fusions.
Am J Surg Pathol. 2014; 38(7):925-933 Doi: 10.1097/PAS.0000000000000187 [OPEN ACCESS]
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** Fried, I; Artl, M; Cota, C; Müller, H; Bartolo, E; Boi, S; Chiarelli, C; Vale, E; Schmuth, M; Wiesner, T; Speicher, MR; Cerroni, L Clinicopathologic and molecular features in cutaneous extranodal natural killer-/T-cell lymphoma, nasal type, with aggressive and indolent course.
J Am Acad Dermatol. 2014; 70(4):716-723 Doi: 10.1016/j.jaad.2013.11.028
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** Lee, W; Teckie, S; Wiesner, T; Ran, L; Prieto Granada, CN; Lin, M; Zhu, S; Cao, Z; Liang, Y; Sboner, A; Tap, WD; Fletcher, JA; Huberman, KH; Qin, LX; Viale, A; Singer, S; Zheng, D; Berger, MF; Chen, Y; Antonescu, CR; Chi, P PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors.
Nat Genet. 2014; 46(11): 1227-1232. Doi: 10.1038/ng.3095 [OPEN ACCESS]
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** Wiesner, T; He, J; Yelensky, R; Esteve-Puig, R; Botton, T; Yeh, I; Lipson, D; Otto, G; Brennan, K; Murali, R; Garrido, M; Miller, VA; Ross, JS; Berger, MF; Sparatta, A; Palmedo, G; Cerroni, L; Busam, KJ; Kutzner, H; Cronin, MT; Stephens, PJ; Bastian, BC Kinase fusions are frequent in Spitz tumours and spitzoid melanomas.
Nat Commun. 2014; 5(5):3116-3116 Doi: 10.1038/ncomms4116 [OPEN ACCESS]
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** Yeh, I; Mully, TW; Wiesner, T; Vemula, SS; Mirza, SA; Sparatta, AJ; McCalmont, TH; Bastian, BC; LeBoit, PE Ambiguous melanocytic tumors with loss of 3p21.
Am J Surg Pathol. 2014; 38(8): 1088-1095. Doi: 10.1097/PAS.0000000000000209 [OPEN ACCESS]
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2013

Full paper/article (Journal)

** Busam, KJ; Sung, J; Wiesner, T; von Deimling, A; Jungbluth, A Combined BRAF(V600E)-positive melanocytic lesions with large epithelioid cells lacking BAP1 expression and conventional nevomelanocytes.
Am J Surg Pathol. 2013; 37(2):193-199 Doi: 10.1097/PAS.0b013e318263648c
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** Busam, KJ; Wanna, M; Wiesner, T Multiple epithelioid Spitz nevi or tumors with loss of BAP1 expression: a clue to a hereditary tumor syndrome.
JAMA Dermatol. 2013; 149(3): 335-339. Doi: 10.1001/jamadermatol.2013.1529 (- Case Report) [OPEN ACCESS]
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** Griewank, KG; Westekemper, H; Murali, R; Mach, M; Schilling, B; Wiesner, T; Schimming, T; Livingstone, E; Sucker, A; Grabellus, F; Metz, C; Süsskind, D; Hillen, U; Speicher, MR; Woodman, SE; Steuhl, KP; Schadendorf, D Conjunctival melanomas harbor BRAF and NRAS mutations and copy number changes similar to cutaneous and mucosal melanomas.
Clin Cancer Res. 2013; 19(12):3143-3152 Doi: 10.1158/1078-0432.CCR-13-0163 [OPEN ACCESS]
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** Kerl, K; Leo, S; Hesse, R; Hesse, B; Gabriela, P; Requena, L; Wiesner, T; Kutzner, H Two-dimensional visualization of multicolor FISH-generated data as a helpful tool for the analysis and understanding of cytogenetic and chromosomal alterations in melanocytic lesions.
Am J Dermatopathol. 2013; 35(2):151-158 Doi: 10.1097/DAD.0b013e318265fd08
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** Mentzel, T; Wiesner, T; Cerroni, L; Hantschke, M; Kutzner, H; Rütten, A; Häberle, M; Bisceglia, M; Chibon, F; Coindre, JM Malignant dermatofibroma: clinicopathological, immunohistochemical, and molecular analysis of seven cases.
Mod Pathol. 2013; 26(2):256-267 Doi: 10.1038/modpathol.2012.157 (- Case Report) [OPEN ACCESS]
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Short report/Letter

** Murali, R; Wilmott, JS; Jakrot, V; Al-Ahmadie, HA; Wiesner, T; McCarthy, SW; Thompson, JF; Scolyer, RA BAP1 expression in cutaneous melanoma: a pilot study.
Pathology. 2013; 45(6): 606-609. Doi: 10.1097/PAT.0b013e3283653818
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Review

** Murali, R; Wiesner, T; Scolyer, RA Tumours associated with BAP1 mutations.
Pathology. 2013; 45(2):116-126 Doi: 10.1097/PAT.0b013e32835d0efb
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** Wiesner, T; Fried, I; Cerroni, L; Kutzner, H Molecular biology methods to improve diagnosis and prognosis of melanocytic tumors.
J Dtsch Dermatol Ges. 2013; 11 Suppl 4(6):19-24 Doi: 10.1111/ddg.12083_supp (- Case Report)
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2012

Full paper/article (Journal)

** Kerl, K; Kempf, W; Kamarashev, J; Spallone, G; Braun, R; Wiesner, T; French, LE; Dummer, R Constitutional intraepidermal ascent of melanocytes: a potential pitfall in the diagnosis of melanocytic lesions.
Arch Dermatol. 2012; 148(2):235-238 Doi: 10.1001/archdermatol.2011.2026 (- Case Report) [OPEN ACCESS]
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** Kerl, K; Palmedo, G; Wiesner, T; Mentzel, T; Rütten, A; Schärer, L; Paredes, B; Hantschke, M; Kutzner, H A proposal for improving multicolor FISH sensitivity in the diagnosis of malignant melanoma using new combined criteria.
Am J Dermatopathol. 2012; 34(6):580-585 Doi: 10.1097/DAD.0b013e3182433f3a
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** Kutzner, H; Metzler, G; Argenyi, Z; Requena, L; Palmedo, G; Mentzel, T; Rütten, A; Hantschke, M; Paredes, BE; Schärer, L; Hesse, B; El-Shabrawi-Caelen, L; Shabrawi-Caelen, LE; Fried, I; Kerl, H; Lorenzo, C; Murali, R; Wiesner, T Histological and genetic evidence for a variant of superficial spreading melanoma composed predominantly of large nests.
Mod Pathol. 2012; 25(6):838-845 Doi: 10.1038/modpathol.2012.35 [OPEN ACCESS]
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** Wiesner, T; Fried, I; Ulz, P; Stacher, E; Popper, H; Murali, R; Kutzner, H; Lax, S; Smolle-Jüttner, F; Geigl, JB; Speicher, MR Toward an improved definition of the tumor spectrum associated with BAP1 germline mutations.
J Clin Oncol. 2012; 30(32):e337-e340 Doi: 10.1200/JCO.2011.41.2965 (- Case Report) [OPEN ACCESS]
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** Wiesner, T; Murali, R; Fried, I; Cerroni, L; Busam, K; Kutzner, H; Bastian, BC A distinct subset of atypical Spitz tumors is characterized by BRAF mutation and loss of BAP1 expression.
Am J Surg Pathol. 2012; 36(6):818-830 Doi: 10.1097/PAS.0b013e3182498be5 [OPEN ACCESS]
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Short report/Letter

** Murali, R; Wiesner, T; Rosenblum, MK; Bastian, BC GNAQ and GNA11 mutations in melanocytomas of the central nervous system.
Acta Neuropathol. 2012; 123(3): 457-459. Doi: 10.1007/s00401-012-0948-x [OPEN ACCESS]
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Abstract (Journal)

** Fried, I; Wiesner, T; Becker, JC; Cerroni, L Subcutaneous panniculitis-like T-cell lymphomas do not show genetic aberrations with array CGH.
Experimental Dermatology. 2012; 21(3):e22--39th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF); March 01-03, 2012; Marburg, Germany. [Poster]
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** Wiesner, T; Obenauf, AC; Murali, R; Fried, I; Griewank, KG; Ulz, P; Windpassinger, C; Wackernagel, W; Loy, S; Wolf, I; Viale, A; Lash, AE; Pirun, M; Socci, ND; Rütten, A; Palmedo, G; Abramson, D; Offit, K; Ott, A; Becker, JC; Cerroni, L; Kutzner, H, Bastian, BC; Speicher, MR Germline mutations in BAP1 predispose to melanocytic tumors.
Experimental Dermatology. 2012; 21(3):e22--39th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF); March 01-03, 2012; Marburg, Germany. [Poster]
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2011

Full paper/article (Journal)

** Gantner, S; Wiesner, T; Cerroni, L; Lurkin, I; Zwarthoff, EC; Landthaler, M; Hafner, C Absence of BRAF and HRAS mutations in eruptive Spitz naevi
BRIT J DERMATOL. 2011; 164(4): 873-877. Doi: 10.1111/j.1365-2133.2011.10210.x (- Case Report)
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** Gulia, A; Saggini, A; Wiesner, T; Fink-Puches, R; Argenyi, Z; Ferrara, G; Müller, CS; Vale, E; Cerroni, L Clinicopathologic features of early lesions of primary cutaneous follicle center lymphoma, diffuse type: implications for early diagnosis and treatment.
J Am Acad Dermatol. 2011; 65(5):991-1000 Doi: 10.1016/j.jaad.2010.06.059
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** Wiesner, T; Obenauf, AC; Murali, R; Fried, I; Griewank, KG; Ulz, P; Windpassinger, C; Wackernagel, W; Loy, S; Wolf, I; Viale, A; Lash, AE; Pirun, M; Socci, ND; Rütten, A; Palmedo, G; Abramson, D; Offit, K; Ott, A; Becker, JC; Cerroni, L; Kutzner, H; Bastian, BC; Speicher, MR Germline mutations in BAP1 predispose to melanocytic tumors.
Nat Genet. 2011; 43(10):1018-1021 Doi: 10.1038/ng.910 [OPEN ACCESS]
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Abstract (Journal)

** Gantner, S; Wiesner, T; Cerroni, L; Lurkin, I; Zwarthoff, E; Landthaler, M; Hafner, C Absence of BRAF and HRAS mutations in eruptive Spitz nevi
EXP DERMATOL. 2011; 20(2):P232--38th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF); FEB 17-19, 2011; Tübingen, GERMANY. [Poster]
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2010

Full paper/article (Journal)

** Cota, C; Vale, E; Viana, I; Requena, L; Ferrara, G; Anemona, L; Metze, D; Fink-Puches, R; Wiesner, T; Cerroni, L Cutaneous manifestations of blastic plasmacytoid dendritic cell neoplasm-morphologic and phenotypic variability in a series of 33 patients.
Am J Surg Pathol. 2010; 34(1):75-87 Doi: 10.1097/PAS.0b013e3181c5e26b
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** Fried, I; Wiesner, T; Cerroni, L Lupus erythematosus with exclusive involvement of the acrosyringia
J CUTANEOUS PATHOL. 2010; 37(1): 91-93. Doi: 10.1111/j.1600-0560.2009.01295.x (- Case Report)
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** Gaiser, T; Kutzner, H; Palmedo, G; Siegelin, MD; Wiesner, T; Bruckner, T; Hartschuh, W; Enk, AH; Becker, MR Classifying ambiguous melanocytic lesions with FISH and correlation with clinical long-term follow up.
Mod Pathol. 2010; 23(3):413-419 Doi: 10.1038/modpathol.2009.177 [OPEN ACCESS]
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** Van Raamsdonk, CD; Griewank, KG; Crosby, MB; Garrido, MC; Vemula, S; Wiesner, T; Obenauf, AC; Wackernagel, W; Green, G; Bouvier, N; Sozen, MM; Baimukanova, G; Roy, R; Heguy, A; Dolgalev, I; Khanin, R; Busam, K; Speicher, MR; O'Brien, J; Bastian, BC Mutations in GNA11 in Uveal Melanoma.
N ENGL J MED. 2010; 363(23): 2191-2199. Doi: 10.1056/NEJMoa1000584 [OPEN ACCESS]
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** Wiesner, T; Obenauf, AC; Cota, C; Fried, I; Speicher, MR; Cerroni, L Alterations of the cell-cycle inhibitors p27(KIP1) and p16(INK4a) are frequent in blastic plasmacytoid dendritic cell neoplasms.
J Invest Dermatol. 2010; 130(4):1152-1157 Doi: 10.1038/jid.2009.369 [OPEN ACCESS]
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Comment

** Fried, I; Wiesner, T; Cerroni, L Pretibial lymphoplasmacytic plaque in children.
Arch Dermatol. 2010; 146(1):95-96 Doi: 10.1001/archdermatol.2009.341 (- Case Report)
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2009

Full paper/article (Journal)

** Cerroni, L; Wiesner, T Cutaneous lymphomas: from morphology to chip technology.
Actas Dermosifiliogr. 2009; 100 Suppl 1(23):3-17 Doi: 10.1016/S0001-7310(09)73164-3
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Short report/Letter

** Wiesner, T; Obenauf, AC; Geigl, JB; Vallant, EM; Speicher, MR; Fink-Puches, R; Kerl, H; Cerroni, L 9p21 deletion in primary cutaneous large B-cell lymphoma, leg type, may escape detection by standard FISH assays.
J Invest Dermatol. 2009; 129(1): 238-240. Doi: 10.1038/jid.2008.224 (- Case Report) [OPEN ACCESS]
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Editorial

** Wiesner, T; Fried, I Gouty Tophi
N ENGL J MED. 2009; 361(21): Doi: 10.1056/NEJMicm0806200 [OPEN ACCESS]
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Abstract (Journal)

** Thomas, W; Obenauf, AC; Speicher, MR; Cerroni, L Genomic characterisation of blastic plasmacytoid dendritic cell neoplasms by array CGH
J INVEST DERMATOL. JID2009; 129: S73-S73.-39th Annual Meeting of the ESDR; SEP 9-12, 2009; Budapest, HUNGARY. [Poster]
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2007

Full paper/article (Journal)

** Wiesner, T; Leinweber, B; Quasthoff, S; Unger, B; Komericki, P; Hoedl, S; Kerl, H Itch, skin lesions--and a stiff neck.
Lancet. 2007; 370(9583): 290-290. Doi: 10.1016/S0140-6736(07)61131-3 (- Case Report)
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2005

Full paper/article (Journal)

** Wiesner, T; Streubel, B; Huber, D; Kerl, H; Chott, A; Cerroni, L Genetic aberrations in primary cutaneous large B-cell lymphoma: a fluorescence in situ hybridization study of 25 cases.
AMER J SURG PATHOL. 2005; 29(5): 666-673. Doi: 10.1097%2F01.pas.0000155163.40668.e7
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