Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Heijman Jordi |

** = Publikationen gelistet in SCI/SSCI/Pubmed

2025

Originalarbeit (Zeitschrift)

** van Cauteren, YJM; Lemmens, MJDK; Bekkers, SCAM; Kietselaer, BLJH; Heijman, J; Theunissen, RALJ; Rahel, B; Voorn, T; van Kuijk, SMJ; Nijveldt, R; Vernooy, K; Wildberger, JE; Mihl, C; Smulders, MW Computed tomography angiography in the diagnosis of non-ST-elevation myocardial infarction: redefining our first line of defense
IJC HEART VASC. 2025; 59: 101690 Doi: 10.1016/j.ijcha.2025.101690
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Übersichtsarbeit

** Kantharia, BK; Tabary, M; Wu, L; Wang, X; Narasimhan, B; Linz, D; Heijman, J; Wehrens, XHT Diabetes and Atrial Fibrillation: Insight From Basic to Translational Science Into the Mechanisms and Management.
J Cardiovasc Electrophysiol. 2025; Doi: 10.1111/jce.16655
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** Kantharia, BK; Zhao, S; Linz, D; Heijman, J; Wehrens, XHT Hypertension and Atrial Fibrillation: Insight From Basic to Translational Science Into the Mechanisms and Management.
J Cardiovasc Electrophysiol. 2025; Doi: 10.1111/jce.16632
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Abstract (Zeitschrift)

** Wen, X; Laudy, L; Meier, S; Heijman, J Computational modeling of calcium-dependent transcriptional regulation of L-type Ca2D channels as driver of atrial fibrillation progression
BIOPHYS J. 2025; 124(3):
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2024

Originalarbeit (Zeitschrift)

** Bodi, I; Mettke, L; Michaelides, K; Hornyik, T; Meier, S; Nimani, S; Perez-Feliz, S; El-Battrawy, I; Bugger, H; Zehender, M; Brunner, M; Heijman, J; Odening, KE Beneficial normalization of cardiac repolarization by carnitine in transgenic SQT1 rabbit models.
Cardiovasc Res. 2024; Doi: 10.1093/cvr/cvae149 [OPEN ACCESS]
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** Fakuade, FE; Hubricht, D; Möller, V; Sobitov, I; Liutkute, A; Döring, Y; Seibertz, F; Gerloff, M; Pronto, JRD; Haghighi, F; Brandenburg, S; Alhussini, K; Ignatyeva, N; Bonhoff, Y; Kestel, S; El-Essawi, A; Jebran, AF; Großmann, M; Danner, BC; Baraki, H; Schmidt, C; Sossalla, S; Kutschka, I; Bening, C; Maack, C; Linke, WA; Heijman, J; Lehnart, SE; Kensah, G; Ebert, A; Mason, FE; Voigt, N Impaired Intracellular Calcium Buffering Contributes to the Arrhythmogenic Substrate in Atrial Myocytes From Patients With Atrial Fibrillation.
Circulation. 2024; 150(7): 544-559. Doi: 10.1161/CIRCULATIONAHA.123.066577 [OPEN ACCESS]
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** Silva, Cunha, P; Laranjo, S; Monteiro, S; Portugal, G; Guerra, C; Rocha, AC; Pereira, M; Ferreira, RC; Heijman, J; Oliveira, MM The impact of atrial voltage and conduction velocity phenotypes on atrial fibrillation recurrence.
Front Cardiovasc Med. 2024; 11: 1427841 Doi: 10.3389/fcvm.2024.1427841 [OPEN ACCESS]
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Kurzbericht/Letter

** Saljic, A; Heijman, J P2X7 receptors: central drivers of the neurocardiac link between atrial fibrillation and depression?
Europace. 2024; 26(2): euae023 Doi: 10.1093/europace/euae023 [OPEN ACCESS]
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Übersichtsarbeit

** Cluitmans, MJM; Plank, G; Heijman, J Digital twins for cardiac electrophysiology: state of the art and future challenges.
Herzschrittmacherther Elektrophysiol. 2024; 35(2):118-123 Doi: 10.1007/s00399-024-01014-0 [OPEN ACCESS]
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** Niskala, A; Heijman, J; Dobrev, D; Jespersen, T; Saljic, A Targeting the NLRP3 inflammasome signalling for the management of atrial fibrillation.
Br J Pharmacol. 2024; Doi: 10.1111/bph.16470
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** Saljic, A; Heijman, J; Dobrev, D From Atrial Small-conductance Calcium-activated Potassium Channels to New Antiarrhythmics
EUR CARDIOL REV. 2024; 19: e26 Doi: 10.15420/ecr.2024.41 [OPEN ACCESS]
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** Schuijt, E; Scherr, D; Plank, G; Schotten, U; Heijman, J Evolution in electrophysiology 100 years after Einthoven: translational and computational innovations in rhythm control of atrial fibrillation.
Europace. 2024; 27(1): Doi: 10.1093/europace/euae304 [OPEN ACCESS]
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** Trayanova, NA; Lyon, A; Shade, J; Heijman, J Computational modeling of cardiac electrophysiology and arrhythmogenesis.
Physiol Rev. 2023; Doi: 10.1152/physrev.00017.2023 [OPEN ACCESS]
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Editorial

** Heijman, J; Madreiter-Sokolowski, CT Is ageing a modifiable risk factor for atrial fibrillation?
Cardiovasc Res. 2024; 120(5):440-442 Doi: 10.1093/cvr/cvae040
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Kommentar

** Heijman, J; Dobrev, D Spexin Hormone Signaling and Atrial Fibrillation: The Knowns and Unknowns.
Circulation. 2024; 150(2): 128-131. Doi: 10.1161/CIRCULATIONAHA.124.070016 [OPEN ACCESS]
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2023

Originalarbeit (Zeitschrift)

** Buonocunto, M; Lyon, A; Delhaas, T; Heijman, J; Lumens, J Electrophysiological effects of stretch-activated ion channels: a systematic computational characterization.
J Physiol. 2023; Doi: 10.1113/JP284439
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** Cachorro, E; Günscht, M; Schubert, M; Sadek, MS; Siegert, J; Dutt, F; Bauermeister, C; Quickert, S; Berning, H; Nowakowski, F; Lämmle, S; Firneburg, R; Luo, X; Künzel, SR; Klapproth, E; Mirtschink, P; Mayr, M; Dewenter, M; Vettel, C; Heijman, J; Lorenz, K; Guan, K; El-Armouche, A; Wagner, M; Kämmerer, S CNP Promotes Antiarrhythmic Effects via Phosphodiesterase 2.
Circ Res. 2023; 132(4): 400-414. Doi: 10.1161/CIRCRESAHA.122.322031 [OPEN ACCESS]
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** Cluitmans, MJM; Bayer, J; Bear, LR; Ter, Bekke, RMA; Heijman, J; Coronel, R; Volders, PGA The circle of reentry: Characteristics of trigger-substrate interaction leading to sudden cardiac arrest.
Front Cardiovasc Med. 2023; 10: 1121517 Doi: 10.3389/fcvm.2023.1121517 [OPEN ACCESS]
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** Heijman, J; Zhou, X; Morotti, S; Molina, CE; Abu-Taha, IH; Tekook, M; Jespersen, T; Zhang, Y; Dobrev, S; Milting, H; Gummert, J; Karck, M; Kamler, M; El-Armouche, A; Saljic, A; Grandi, E; Nattel, S; Dobrev, D Enhanced Ca2+-Dependent SK-Channel Gating and Membrane Trafficking in Human Atrial Fibrillation.
Circ Res. 2023; 132(9): e116-e133. Doi: 10.1161/CIRCRESAHA.122.321858 [OPEN ACCESS]
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** Herrera, NT; Zhang, X; Ni, H; Maleckar, MM; Heijman, J; Dobrev, D; Grandi, E; Morotti, S Dual effects of the small-conductance Ca2+-activated K+ current on human atrial electrophysiology and Ca2+-driven arrhythmogenesis: an in silico study.
Am J Physiol Heart Circ Physiol. 2023; 325(4): H896-H908. Doi: 10.1152/ajpheart.00362.2023 [OPEN ACCESS]
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** Meier, S; Grundland, A; Dobrev, D; Volders, PGA; Heijman, J In silico analysis of the dynamic regulation of cardiac electrophysiology by Kv 11.1 ion-channel trafficking.
J Physiol. 2023; 601(13): 2711-2731. Doi: 10.1113/JP283976 [OPEN ACCESS]
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** Seibertz, F; Sutanto, H; Dülk, R; Pronto, JRD; Springer, R; Rapedius, M; Liutkute, A; Ritter, M; Jung, P; Stelzer, L; Hüsgen, LM; Klopp, M; Rubio, T; Fakuade, FE; Mason, FE; Hartmann, N; Pabel, S; Streckfuss-Bömeke, K; Cyganek, L; Sossalla, S; Heijman, J; Voigt, N Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes.
Basic Res Cardiol. 2023; 118(1): 14 Doi: 10.1007/s00395-022-00973-0 [OPEN ACCESS]
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** Wang, X; Song, J; Yuan, Y; Li, L; Abu-Taha, I; Heijman, J; Sun, L; Dobrev, S; Kamler, M; Xie, L; Wehrens, XHT; Horrigan, FT; Dobrev, D; Li, N Downregulation of FKBP5 Promotes Atrial Arrhythmogenesis.
Circ Res. 2023; 133(1): e1-e16. Doi: 10.1161/CIRCRESAHA.122.322213 [OPEN ACCESS]
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Übersichtsarbeit

** Gawałko, M; Saljic, A; Li, N; Abu-Taha, I; Jespersen, T; Linz, D; Nattel, S; Heijman, J; Fender, A; Dobrev, D Adiposity-associated atrial fibrillation: molecular determinants, mechanisms, and clinical significance.
Cardiovasc Res. 2023; 119(3): 614-630. Doi: 10.1093/cvr/cvac093 [OPEN ACCESS]
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** Remme, CA; Heijman, J; Gomez, AM; Zaza, A; Odening, KE 25 years of basic and translational science in EP Europace: novel insights into arrhythmia mechanisms and therapeutic strategies.
Europace. 2023; 25(8): Doi: 10.1093/europace/euad210 [OPEN ACCESS]
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** Saljic, A; Heijman, J; Dobrev, D Recent Advances in Antiarrhythmic Drug Therapy.
Drugs. 2023; 83(13): 1147-1160. Doi: 10.1007/s40265-023-01923-3 [OPEN ACCESS]
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** Steffens, S; Schröder, K; Krüger, M; Maack, C; Streckfuss-Bömeke, K; Backs, J; Backofen, R; Baeßler, B; Devaux, Y; Gilsbach, R; Heijman, J; Knaus, J; Kramann, R; Linz, D; Lister, AL; Maatz, H; Maegdefessel, L; Mayr, M; Meder, B; Nussbeck, SY; Rog-Zielinska, EA; Schulz, MH; Sickmann, A; Yigit, G; Kohl, P The challenges of research data management in cardiovascular science: a DGK and DZHK position paper-executive summary.
Clin Res Cardiol. 2023; Doi: 10.1007/s00392-023-02303-3 [OPEN ACCESS]
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Kommentar

** Heijman, J; Christ, T Mind the gap: leak currents and induced pluripotent stem cell-derived cardiomyocytes in translational cardiac electrophysiology.
Europace. 2023; 25(9): Doi: 10.1093/europace/euad236 [OPEN ACCESS]
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2022

Originalarbeit (Zeitschrift)

** Scheurlen, C; van den Bruck, JH; Filipovic, K; Wörmann, J; Arica, Z; Erlhöfer, S; Dittrich, S; Heijman, J; Lüker, J; Steven, D; Sultan, A Procedural and outcome impact of obesity in cryoballoon versus radiofrequency pulmonary vein isolation in atrial fibrillation patients
J INTERV CARD ELECTR. 2022; 65(2): 403-410. Doi: 10.1007/s10840-022-01210-3 [OPEN ACCESS]
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** Sutanto, H; Heijman, J Integrative Computational Modeling of Cardiomyocyte Calcium Handling and Cardiac Arrhythmias: Current Status and Future Challenges
CELLS-BASEL. 2022; 11(7): 1090 Doi: 10.3390/cells11071090 [OPEN ACCESS]
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** Wiedmann, F; Beyersdorf, C; Zhou, XB; Kraft, M; Paasche, A; Jávorszky, N; Rinné, S; Sutanto, H; Büscher, A; Foerster, K; Blank, A; El-Battrawy, I; Li, X; Lang, S; Tochtermann, U; Kremer, J; Arif, R; Karck, M; Decher, N; van Loon, G; Akin, I; Borggrefe, M; Kallenberger, S; Heijman, J; Haefeli, WE; Katus, HA; Schmidt, C Treatment of atrial fibrillation with doxapram: TASK-1 potassium channel inhibition as a novel pharmacological strategy
CARDIOVASC RES. 2022; 118(7): 1728-1741. Doi: 10.1093/cvr/cvab177
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Übersichtsarbeit

** Colman, MA; Alvarez-Lacalle, E; Echebarria, B; Sato, D; Sutanto, H; Heijman, J Multi-Scale Computational Modeling of Spatial Calcium Handling From Nanodomain to Whole-Heart: Overview and Perspectives
FRONT PHYSIOL. 2022; 13: 836622 Doi: 10.3389/fphys.2022.836622 [OPEN ACCESS]
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** Saljic, A; Heijman, J; Dobrev, D Emerging Antiarrhythmic Drugs for Atrial Fibrillation
INT J MOL SCI. 2022; 23(8): 4096 Doi: 10.3390/ijms23084096 [OPEN ACCESS]
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2021

Originalarbeit (Zeitschrift)

** Cluitmans, MJM; Bear, LR; Nguyên, UC; van Rees, B; Stoks, J; ter Bekke, RMA; Mihl, C; Heijman, J; Lau, KD; Vigmond, E; Bayer, J; Belterman, CNW; Abell, E; Labrousse, L; Rogier, J; Bernus, O; Haïssaguerre, M; Hassink, RJ; Dubois, R; Coronel, R; Volders, PGA Noninvasive detection of spatiotemporal activation-repolarization interactions that prime idiopathic ventricular fibrillation
SCI TRANSL MED. 2021; 13(620): eabi9317 Doi: 10.1126/scitranslmed.abi9317
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** Fabritz, L; Crijns, HJGM; Guasch, E; Goette, A; Häusler, KG; Kotecha, D; Lewalter, T; Meyer, C; Potpara, TS; Rienstra, M; Schnabel, RB; Willems, S; Breithardt, G; Camm, AJ; Chan, A; Chua, W; de Melis, M; Dimopoulou, C; Dobrev, D; Easter, C; Eckardt, L; Haase, D; Hatem, S; Healey, JS; Heijman, J; Hohnloser, SH; Huebner, T; Ilyas, BS; Isaacs, A; Kutschka, I; Leclercq, C; Lip, GYH; Marinelli, EA; Merino, JL; Mont, L; Nabauer, M; Oldgren, J; Pürerfellner, H; Ravens, U; Savelieva, I; Sinner, MF; Sitch, A; Smolnik, R; Steffel, J; Stein, K; Stoll, M; Svennberg, E; Thomas, D; Van Gelder, IC; Vardar, B; Wakili, R; Wieloch, M; Zeemering, S; Ziegler, PD; Heidbuchel, H; Hindricks, G; Schotten, U; Kirchhof, P Dynamic risk assessment to improve quality of care in patients with atrial fibrillation: the 7th AFNET/EHRA Consensus Conference
EUROPACE. 2021; 23(3): 329-344. Doi: 10.1093/europace/euaa279
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** Heijman, J; Hohnloser, SH; Camm, AJ Antiarrhythmic drugs for atrial fibrillation: lessons from the past and opportunities for the future
EUROPACE. 2021; 23: 14-22. Doi: 10.1093/europace/euaa426
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** Lyon, A; van Mourik, M; Cruts, L; Heijman, J; Bekkers, SCAM; Schotten, U; Crijns, HJGM; Linz, D; Lumens, J Both beat-to-beat changes in RR-interval and left ventricular filling time determine ventricular function during atrial fibrillation
EUROPACE. 2021; 23: I21-I28. Doi: 10.1093/europace/euaa387 [OPEN ACCESS]
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** Lyon, A; van Opbergen, CJM; Delmar, M; Heijman, J; van Veen, TAB In silico Identification of Disrupted Myocardial Calcium Homeostasis as Proarrhythmic Trigger in Arrhythmogenic Cardiomyopathy
FRONT PHYSIOL. 2021; 12: 732573 Doi: 10.3389/fphys.2021.732573 [OPEN ACCESS]
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** Nedios, S; Löbe, S; Knopp, H; Seewöster, T; Heijman, J; Crijns, HJGM; Arya, A; Bollmann, A; Hindricks, G; Dinov, B Left atrial activation and asymmetric anatomical remodeling in patients with atrial fibrillation: The relation between anatomy and function
CLIN CARDIOL. 2021; 44(1): 116-122. Doi: 10.1002/clc.23515 [OPEN ACCESS]
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** Nedios, S; Sanatkhani, S; Oladosu, M; Seewöster, T; Richter, S; Arya, A; Heijman, J; Crijns, HJGM; Hindricks, G; Bollmann, A; Menon, PG Association of low-voltage areas with the regional wall deformation and the left atrial shape in patients with atrial fibrillation: A proof of concept study
IJC HEART VASC. 2021; 33: 100730 Doi: 10.1016/j.ijcha.2021.100730 [OPEN ACCESS]
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** Odening, KE; Gomez, AM; Dobrev, D; Fabritz, L; Heinzel, FR; Mangoni, ME; Molina, CE; Sacconi, L; Smith, G; Stengl, M; Thomas, D; Zaza, A; Remme, CA; Heijman, J ESC working group on cardiac cellular electrophysiology position paper: relevance, opportunities, and limitations of experimental models for cardiac electrophysiology research
EUROPACE. 2021; 23(11): 1795-1814. Doi: 10.1093/europace/euab142 [OPEN ACCESS]
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** Peper, J; Kownatzki-Danger, D; Weninger, G; Seibertz, F; Pronto, JRD; Sutanto, H; Pacheu-Grau, D; Hindmarsh, R; Brandenburg, S; Kohl, T; Hasenfuss, G; Gotthardt, M; Rog-Zielinska, EA; Wollnik, B; Rehling, P; Urlaub, H; Wegener, J; Heijman, J; Voigt, N; Cyganek, L; Lenz, C; Lehnart, SE Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes
CIRC RES. 2021; 128(6): E102-E120. Doi: 10.1161/CIRCRESAHA.119.316547
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** Sultan, A; Wörmann, J; Lüker, J; van der Bruck, JH; Plenge, T; Rudolph, V; Klinke, A; Heijman, J; Mollenhauer, M; Ravekes, T; Baldus, S; Steven, D Significance of myeloperoxidase plasma levels as a predictor for cardiac resynchronization therapy response
CLIN RES CARDIOL. 2021; 110(8): 1173-1180. Doi: 10.1007/s00392-020-01690-1 [OPEN ACCESS]
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** Vagos, MR; Arevalo, H; Heijman, J; Schotten, U; Sundnes, J A Computational Study of the Effects of Tachycardia-Induced Remodeling on Calcium Wave Propagation in Rabbit Atrial Myocytes
FRONT PHYSIOL. 2021; 12: 651428 Doi: 10.3389/fphys.2021.651428 [OPEN ACCESS]
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** van Cauteren, YJM; Smulders, MW; Theunissen, RALJ; Gerretsen, SC; Adriaans, BP; Bijvoet, GP; Mingels, AMA; van Kuijk, SMJ; Schalla, S; Crijns, HJGM; Kim, RJ; Wildberger, JE; Heijman, J; Bekkers, SCAM Cardiovascular magnetic resonance accurately detects obstructive coronary artery disease in suspected non-ST elevation myocardial infarction: a sub-analysis of the CARMENTA Trial
J CARDIOVASC MAGN R. 2021; 23(1): 40 Doi: 10.1186/s12968-021-00723-6 [OPEN ACCESS]
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** Wagner, M; Sadek, MS; Dybkova, N; Mason, FE; Klehr, J; Firneburg, R; Cachorro, E; Richter, K; Klapproth, E; Kuenzel, SR; Lorenz, K; Heijman, J; Dobrev, D; El-Armouche, A; Sossalla, S; Kämmerer, S Cellular Mechanisms of the Anti-Arrhythmic Effect of Cardiac PDE2 Overexpression
INT J MOL SCI. 2021; 22(9): 4816 Doi: 10.3390/ijms22094816 [OPEN ACCESS]
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** Xenakis, MN; Kapetis, D; Yang, Y; Gerrits, MM; Heijman, J; Waxman, SG; Lauria, G; Faber, CG; Westra, RL; Lindsey, PJ; Smeets, HJ Hydropathicity-based prediction of pain-causing NaV1.7 variants
BMC BIOINFORMATICS. 2021; 22(1): 212 Doi: 10.1186/s12859-021-04119-2 [OPEN ACCESS]
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** Xenakis, MN; Kapetis, D; Yang, Y; Heijman, J; Waxman, SG; Lauria, G; Faber, CG; Smeets, HJ; Lindsey, PJ; Westra, RL Non-extensitivity and criticality of atomic hydropathicity around a voltage-gated sodium channel's pore: a modeling study
J BIOL PHYS. 2021; 47(1): 61-77. Doi: 10.1007/s10867-021-09565-w [OPEN ACCESS]
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Kurzbericht/Letter

** Lyon, A; van Mourik, M; Cruts, L; Heijman, J; Bekkers, SCAM; Schotten, U; Crijns, HJGM; Linz, D; Lumens, J Understanding the effects of heart beat irregularity on ventricular function in human atrial fibrillation: simulation models may help to untie the knot-Authors' reply
EUROPACE. 2021; 23(11): 1869-1869. Doi: 10.1093/europace/euab144 [OPEN ACCESS]
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Übersichtsarbeit

** Heijman, J; Linz, D; Schotten, U Dynamics of Atrial Fibrillation Mechanisms and Comorbidities
ANNU REV PHYSIOL. 2021; 83: 83-106. Doi: 10.1146/annurev-physiol-031720-085307
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** Heijman, J; Luermans, JGLM; Linz, D; van, Gelder, IC; Crijns, HJGM Risk Factors for Atrial Fibrillation Progression.
Card Electrophysiol Clin. 2021; 13(1): 201-209. Doi: 10.1016/j.ccep.2020.10.011
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** Heijman, J; Sutanto, H; Crijns, HJGM; Nattel, S; Trayanova, NA Computational models of atrial fibrillation: achievements, challenges, and perspectives for improving clinical care
CARDIOVASC RES. 2021; 117(7): 1682-1699. Doi: 10.1093/cvr/cvab138 [OPEN ACCESS]
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** Nattel, S; Sager, PT; Hüser, J; Heijman, J; Dobrev, D Why translation from basic discoveries to clinical applications is so difficult for atrial fibrillation and possible approaches to improving it
CARDIOVASC RES. 2021; 117(7): 1616-1631. Doi: 10.1093/cvr/cvab093 [OPEN ACCESS]
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** Sutanto, H; Dobrev, D; Heijman, J Angiotensin Receptor-Neprilysin Inhibitor (ARNI) and Cardiac Arrhythmias
INT J MOL SCI. 2021; 22(16): 8994 Doi: 10.3390/ijms22168994 [OPEN ACCESS]
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Editorial

** Aguilar, M; Heijman, J; Dobrev, D; Nattel, S One Ring to Rule Them All: Continuous Monitoring of Patients With Secondary Atrial Fibrillation Points to a Unifying Underlying Mechanism
CAN J CARDIOL. 2021; 37(5): 686-689. Doi: 10.1016/j.cjca.2021.01.018
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** Heijman, J; Ghossein, MA; Vernooy, K; Linz, D The walk of life: Remote monitoring provides insights into physical activity during a pandemic
IJC HEART VASC. 2021; 33: 100772 Doi: 10.1016/j.ijcha.2021.100772 [OPEN ACCESS]
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** Heijman, J; Rahm, AK; Dobrev, D Stretching the limits of antiarrhythmic drug therapy: The promise of small-conductance calcium-activated potassium channel blockers
IJC HEART VASC. 2021; 37: 100924 Doi: 10.1016/j.ijcha.2021.100924 [OPEN ACCESS]
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** Heijman, J; Vernooy, K; C van Gelder, I The road goes ever on: innovations and paradigm shifts in atrial fibrillation management
EUROPACE. 2021; 23: 1-3. Doi: 10.1093/europace/euab061
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** Nedios, S; Lindemann, F; Heijman, J; Crijns, HJGM; Bollmann, A; Hindricks, G Atrial remodeling and atrial fibrillation recurrence after catheter ablation Past, present, and future developments
HERZ. 2021; 46(4): 312-317. Doi: 10.1007/s00059-021-05050-1
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** Ravens, U; Gomez, AM; Heijman, J; Remme, CA; Dobrev, D; Smith, G; Volders, PGA; Cerbai, E; Eisner, DA; Casadei, B; Zaza, A; Richard, S; Mugelli, A; Vassort, G; Brown, HF; Sipido, KR Edward Carmeliet (1930-2021)-channelling scientific curiosity: a tribute from the ESC Working Group on Cardiac Cellular Electrophysiology
CARDIOVASC RES. 2021; 117(14): E171-E173. Doi: 10.1093/cvr/cvab333
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2020

Originalarbeit (Zeitschrift)

** Altrocchi, C; de Korte, T; Bernardi, J; Spätjens, RLHMG; Braam, SR; Heijman, J; Zaza, A; Volders, PGA Repolarization instability and arrhythmia by IKr block in single human-induced pluripotent stem cell-derived cardiomyocytes and 2D monolayers
EUROPACE. 2020; 22(9): 1431-1441. Doi: 10.1093/europace/euaa111 [OPEN ACCESS]
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** Coopmans, C; Zhou, TL; Henry, RMA; Heijman, J; Schaper, NC; Koster, A; Schram, MT; van der Kallen, CJH; Wesselius, A; den Engelsman, RJA; Crijns, HJGM; Stehouwer, CDA Both Prediabetes and Type 2 Diabetes Are Associated With Lower Heart Rate Variability: The Maastricht Study
DIABETES CARE. 2020; 43(5): 1126-1133. Doi: 10.2337/dc19-2367
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** Heijman, J; Muna, AP; Veleva, T; Molina, CE; Sutanto, H; Tekook, M; Wang, QL; Abu-Taha, IH; Gorka, M; Künzel, S; El-Armouche, A; Reichenspurner, H; Kamler, M; Nikolaev, V; Ravens, U; Li, N; Nattel, S; Wehrens, XHT; Dobrev, D Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Postoperative Atrial Fibrillation
CIRC RES. 2020; 127(8): 1036-1055. Doi: 10.1161/CIRCRESAHA.120.316710 [OPEN ACCESS]
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** Lyon, A; Dupuis, LJ; Arts, T; Crijns, HJGM; Prinzen, FW; Delhaas, T; Heijman, J; Lumens, J Differentiating the effects of β-adrenergic stimulation and stretch on calcium and force dynamics using a novel electromechanical cardiomyocyte model
AM J PHYSIOL-HEART C. 2020; 319(3): H519-H530. Doi: 10.1152/ajpheart.00275.2020
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** Nattel, S; Heijman, J; Zhou, LP; Dobrev, D Molecular Basis of Atrial Fibrillation Pathophysiology and Therapy A Translational Perspective
CIRC RES. 2020; 127(1): 51-72. Doi: 10.1161/CIRCRESAHA.120.316363 [OPEN ACCESS]
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** Sutanto, H; Cluitmans, MJM; Dobrev, D; Volders, PGA; Bébarová, M; Heijman, J Acute effects of alcohol on cardiac electrophysiology and arrhythmogenesis: Insights from multiscale in silico analyses
J MOL CELL CARDIOL. 2020; 146: 69-83. Doi: 10.1016/j.yjmcc.2020.07.007
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** Sutanto, H; Heijman, J Beta-Adrenergic Receptor Stimulation Modulates the Cellular Proarrhythmic Effects of Chloroquine and Azithromycin
FRONT PHYSIOL. 2020; 11: 587709 Doi: 10.3389/fphys.2020.587709
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** Sutanto, H; Lyon, A; Lumens, J; Schotten, U; Dobrev, D; Heijman, J Cardiomyocyte calcium handling in health and disease: Insights from in vitro and in silico studies
PROG BIOPHYS MOL BIO. 2020; 157: 54-75. Doi: 10.1016/j.pbiomolbio.2020.02.008
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** Vagos, MR; Arevalo, H; Hiejman, J; Schotten, U; Sundnes, J A Novel Computational Model of the Rabbit Atrial Cardiomyocyte With Spatial Calcium Dynamics
FRONT PHYSIOL. 2020; 11: 556156 Doi: 10.3389/fphys.2020.556156
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** Vranken, NPA; Pustjens, TFS; Kolkman, E; Hermanides, RS; Bekkers, SCAM; Smulders, MW; van Cauteren, YJM; Heijman, J; Rasoul, S; Ottervanger, JP; van't Hof, AWJ MINOCA: The caveat of absence of coronary obstruction in myocardial infarction
IJC HEART VASC. 2020; 29: 100572 Doi: 10.1016/j.ijcha.2020.100572 [OPEN ACCESS]
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** Xenakis, MN; Kapetis, D; Yang, Y; Heijman, J; Waxman, SG; Lauria, G; Faber, CG; Smeets, HJ; Westra, RL; Lindsey, PJ Cumulative hydropathic topology of a voltage-gated sodium channel at atomic resolution
PROTEINS. 2020; 88(10): 1319-1328. Doi: 10.1002/prot.25951
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Übersichtsarbeit

** Bogossian, H; Linz, D; Heijman, J; Bimpong-Buta, NY; Bandorski, D; Frommeyer, G; Erkapic, D; Seyfarth, M; Zarse, M; Crijns, HJ QTc evaluation in patients with bundle branch block
IJC HEART VASC. 2020; 30: 100636 Doi: 10.1016/j.ijcha.2020.100636 [OPEN ACCESS]
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Editorial

** Espinosa, CB; Hemels, MEW; Dobrev, D; Heijman, J Recurrence of atrial fibrillation following non-cardiac surgery or acute illness: A common but rarely detected complication
IJC HEART VASC. 2020; 29: 100609 Doi: 10.1016/j.ijcha.2020.100609 [OPEN ACCESS]
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** Gómez, AM; Heijman, J; Remme, CA The ESCWorking Group Cardiac Cellular Electrophysiology
EUR HEART J. 2020; 41(46): 4374-4376.
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** Linz, D; Linz, B; Heijman, J Sleep Apnea, Intermittent Hypoxemia, and Effects on Ischemic Myocardial Damage: Friend or Foe?
CAN J CARDIOL. 2020; 36(6): 809-812. Doi: 10.1016/j.cjca.2020.02.075
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2019

Originalarbeit (Zeitschrift)

** Sutanto, H; Laudy, L; Clerx, M; Dobrev, D; Crijns, HJGM; Heijman, J Maastricht antiarrhythmic drug evaluator (MANTA): A computational tool for better understanding of antiarrhythmic drugs
PHARMACOL RES. 2019; 148: 104444 Doi: 10.1016/j.phrs.2019.104444
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** van Mourik, MJW; Zaar, DVJ; Smulders, MW; Heijman, J; Lumens, J; Dokter, JE; Passos, VL; Schalla, S; Knackstedt, C; Schummers, G; Gjesdal, O; Edvardsen, T; Bekkers, SCAM Adding Speckle-Tracking Echocardiography to Visual Assessment of Systolic Wall Motion Abnormalities Improves the Detection of Myocardial Infarction
J AM SOC ECHOCARDIOG. 2019; 32(1): 65-73. Doi: 10.1016/j.echo.2018.09.007
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Übersichtsarbeit

** Dobrev, D; Aguilar, M; Heijman, J; Guichard, JB; Nattel, S Postoperative atrial fibrillation: mechanisms, manifestations and management
NAT REV CARDIOL. 2019; 16(7): 417-436. Doi: 10.1038/s41569-019-0166-5
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** Grandi, E; Dobrev, D; Heijman, J Computational modeling: What does it tell us about atrial fibrillation therapy?
INT J CARDIOL. 2019; 287: 155-161. Doi: 10.1016/j.ijcard.2019.01.077 [OPEN ACCESS]
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** Thomas, D; Christ, T; Fabritz, L; Goette, A; Hammwöhner, M; Heijman, J; Kockskämper, J; Linz, D; Odening, KE; Schweizer, PA; Wakili, R; Voigt, N German Cardiac Society Working Group on Cellular Electrophysiology state-of-the-art paper: impact of molecular mechanisms on clinical arrhythmia management
CLIN RES CARDIOL. 2019; 108(6): 577-599. Doi: 10.1007/s00392-018-1377-1
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Editorial

** Heijman, J; Dobrev, D Bayesian network analyses in atrial fibrillation - A path to better therapies?
IJC HEART VASC. 2019; 22: 210-211. Doi: 10.1016/j.ijcha.2019.02.009 [OPEN ACCESS]
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** Linz, D; Ammirati, E; Dan, GA; Heijman, J; Dobrev, D Highlights from the International Journal of Cardiology Heart & Vasculature: Heart failure, atrial fibrillation, coronary artery disease and myocardial infarction
IJC HEART VASC. 2019; 25: 100443 Doi: 10.1016/j.ijcha.2019.100443 [OPEN ACCESS]
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** Sutanto, H; Dobrev, D; Heijman, J Genome-wide association studies of atrial fibrillation: Finding meaning in the life of risk loci
IJC HEART VASC. 2019; 24: 100397 Doi: 10.1016/j.ijcha.2019.100397 [OPEN ACCESS]
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2018

Originalarbeit (Zeitschrift)

** Abu-Taha, IH; Heijman, J; Feng, Y; Vettel, C; Dobrev, D; Wieland, T Regulation of heterotrimeric G-protein signaling by NDPK/NME proteins and caveolins: an update
LAB INVEST. 2018; 98(2): 190-197. Doi: 10.1038/labinvest.2017.103
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** Clerx, M; Heijman, J; Collins, P; Volders, PGA Predicting changes to INa from missense mutations in human SCN5A
SCI REP-UK. 2018; 8: 12797 Doi: 10.1038/s41598-018-30577-5 [OPEN ACCESS]
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** Heijman, J; Kirchner, D; Kunze, F; Chrétien, EM; Michel-Reher, MB; Voigt, N; Knaut, M; Michel, MC; Ravens, U; Dobrev, D Muscarinic type-1 receptors contribute to IK,ACh in human atrial cardiomyocytes and are upregulated in patients with chronic atrial fibrillation
INT J CARDIOL. 2018; 255: 61-68. Doi: 10.1016/j.ijcard.2017.12.050 [OPEN ACCESS]
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** Molina, CE; Abu-Taha, IH; Wang, QL; Roselló-Díez, E; Kamler, M; Nattel, S; Ravens, U; Wehrens, XHT; Hove-Madsen, L; Heijman, J; Dobrev, D Profibrotic, Electrical, and Calcium-Handling Remodeling of the Atria in Heart Failure Patients With and Without Atrial Fibrillation
FRONT PHYSIOL. 2018; 9: 1383 Doi: 10.3389/fphys.2018.01383 [OPEN ACCESS]
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** Nguyên, UC; Potse, M; Vernooy, K; Mafi-Rad, M; Heijman, J; Caputo, ML; Conte, G; Regoli, F; Krause, R; Moccetti, T; Auricchio, A; Prinzen, FW; Maffessanti, F A left bundle branch block activation sequence and ventricular pacing influence voltage amplitudes: an in vivo and in silico study
EUROPACE. 2018; 20: 77-86. Doi: 10.1093/europace/euy233
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** Sutanto, H; van Sloun, B; Schönleitner, P; van Zandvoort, MAMJ; Antoons, G; Heijman, J The Subcellular Distribution of Ryanodine Receptors and L-Type Ca2+ Channels Modulates Ca2+-Transient Properties and Spontaneous Ca2+-Release Events in Atrial Cardiomyocytes
FRONT PHYSIOL. 2018; 9: 1108 Doi: 10.3389/fphys.2018.01108 [OPEN ACCESS]
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Übersichtsarbeit

** Heijman, J; Dobrev, D Ion channels as part of macromolecular multiprotein complexes : Clinical significance.
Herzschrittmacherther Elektrophysiol. 2018; 29(1): 30-35. Doi: 10.1007/s00399-017-0542-y [OPEN ACCESS]
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** Heijman, J; Guichard, JB; Dobrev, D; Nattel, S Translational Challenges in Atrial Fibrillation
CIRC RES. 2018; 122(5): 752-773. Doi: 10.1161/CIRCRESAHA.117.311081
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Editorial

** Heijman, J; Dobrev, D; Crijns, HJGM Electrocardiographic characteristics associated with atrial fibrillation - What do they tell us?
INT J CARDIOL. 2018; 266: 143-144. Doi: 10.1016/j.ijcard.2018.04.071
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** Sutanto, H; Dobrev, D; Heijman, J Resveratrol: an effective pharmacological agent to prevent inflammation-induced atrial fibrillation?
N-S ARCH PHARMACOL. 2018; 391(11): 1163-1167. Doi: 10.1007/s00210-018-1566-5
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2017

Originalarbeit (Zeitschrift)

** Abu-Taha, IH; Heijman, J; Hippe, HJ; Wolf, NM; El-Armouche, A; Nikolaev, VO; Schäfer, M; Würtz, CM; Neef, S; Voigt, N; Baczkó, I; Varró, A; Müller, M; Meder, B; Katus, HA; Spiger, K; Vettel, C; Lehmann, LH; Backs, J; Skolnik, EY; Lutz, S; Dobrev, D; Wieland, T Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure
CIRCULATION. 2017; 135(9): 881-897. Doi: 10.1161/CIRCULATIONAHA.116.022852
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** Chiamvimonvat, N; Ye, CI; Clancy, CE; Deschenes, I; Dobrev, D; Heijman, J; Izu, L; Qu, ZL; Ripplinger, CM; Vandenberg, JI; Weiss, JN; Koren, G; Banyasz, T; Grandi, E; Sanguinetti, MC; Bers, DM; Nerbonne, JM Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics
J PHYSIOL-LONDON. 2017; 595(7): 2229-2252. Doi: 10.1113/JP272883 [OPEN ACCESS]
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** Grandi, E; Sanguinetti, MC; Bartos, DC; Bers, DM; Ye, CI; Chiamvimonvat, N; Colecraft, HM; Delisle, BP; Heijman, J; Navedo, MF; Noskov, S; Proenza, C; Vandenberg, JI; Yarov-Yarovoy, V Potassium channels in the heart: structure, function and regulation
J PHYSIOL-LONDON. 2017; 595(7): 2209-2228. Doi: 10.1113/JP272864 [OPEN ACCESS]
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** Heijman, J; Ghezelbash, S; Wehrens, XHT; Dobrev, D Serine/Threonine Phosphatases in Atrial Fibrillation
J MOL CELL CARDIOL. 2017; 103: 110-120. Doi: 10.1016/j.yjmcc.2016.12.009 [OPEN ACCESS]
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** Neef, S; Heijman, J; Otte, K; Dewenter, M; Saadatmand, AR; Meyer-Roxlau, S; Antos, CL; Backs, J; Dobrev, D; Wagner, M; Maier, LS; El-Armouche, A Chronic loss of inhibitor-1 diminishes cardiac RyR2 phosphorylation despite exaggerated CaMKII activity
N-S ARCH PHARMACOL. 2017; 390(8): 857-862. Doi: 10.1007/s00210-017-1376-1
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** Schmidt, C; Wiedmann, F; Zhou, XB; Heijman, J; Voigt, N; Ratte, A; Lang, S; Kallenberger, SM; Campana, C; Weymann, A; De Simone, R; Szabo, G; Ruhparwar, A; Kallenbach, K; Karck, M; Ehrlich, JR; Baczkó, I; Borggrefe, M; Ravens, U; Dobrev, D; Katus, HA; Thomas, D Inverse remodelling of K2P3.1 K+ channel expression and action potential duration in left ventricular dysfunction and atrial fibrillation: implications for patient-specific antiarrhythmic drug therapy
EUR HEART J. 2017; 38(22): 1764-1774. Doi: 10.1093/eurheartj/ehw559
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** Tomek, J; Rodriguez, B; Bub, G; Heijman, J β-Adrenergic receptor stimulation inhibits proarrhythmic alternans in postinfarction border zone cardiomyocytes: a computational analysis
AM J PHYSIOL-HEART C. 2017; 313(2): H338-H353. Doi: 10.1152/ajpheart.00094.2017 [OPEN ACCESS]
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Übersichtsarbeit

** Heijman, J; Ghezelbash, S; Dobrev, D Investigational antiarrhythmic agents: promising drugs in early clinical development
EXPERT OPIN INV DRUG. 2017; 26(8): 897-907. Doi: 10.1080/13543784.2017.1353601 [OPEN ACCESS]
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Editorial

** Heijman, J; Dobrev, D Inhibition of Small-Conductance Ca2+-Activated K+ Channels The Long-Awaited Breakthrough for Antiarrhythmic Drug Therapy of Atrial Fibrillation?
CIRC-ARRHYTHMIA ELEC. 2017; 10(10): e005776 Doi: 10.1161/CIRCEP.117.005776 [OPEN ACCESS]
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** Heijman, J; Dobrev, D; Crijns, HJGM Targeting supraventricular ectopic complexes: Which approach should be used and how does it affect atrial fibrillation?
INT J CARDIOL. 2017; 244: 202-203. Doi: 10.1016/j.ijcard.2017.06.013
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2016

Originalarbeit (Zeitschrift)

** Molina, CE; Heijman, J; Dobrev, D Differences in Left Versus Right Ventricular Electrophysiological Properties in Cardiac Dysfunction and Arrhythmogenesis
ARRHYTH ELECTROPHYSI. 2016; 5(1): 14-19. Doi: 10.15420/AER.2016.8.2 [OPEN ACCESS]
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Kurzbericht/Letter

** Schmidt, C; Wiedmann, F; Voigt, N; Zhou, XB; Heijman, J; Lang, S; Albert, V; Kallenberger, S; Ruhparwar, A; Szabó, G; Kallenbach, K; Karck, M; Borggrefe, M; Biliczki, P; Ehrlich, JR; Baczkó, I; Lugenbiel, P; Schweizer, PA; Donner, BC; Katus, HA; Dobrev, D; Thomas, D Response to Letter Regarding Article, "Upregulation of K 2P 3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation"
CIRCULATION. 2016; 133(11): E440-E441. Doi: 10.1161/CIRCULATIONAHA.115.020662
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Übersichtsarbeit

** Heijman, J; Abdoust, PE; Voigt, N; Nattel, S; Dobrev, D Computational models of atrial cellular electrophysiology and calcium handling, and their role in atrial fibrillation
J PHYSIOL-LONDON. 2016; 594(3): 537-553. Doi: 10.1113/JP271404 [OPEN ACCESS]
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** Heijman, J; Algalarrondo, V; Voigt, N; Melka, J; Wehrens, XHT; Dobrev, D; Nattel, S The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis
CARDIOVASC RES. 2016; 109(4): 467-479. Doi: 10.1093/cvr/cvv275 [OPEN ACCESS]
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Editorial

** Heijman, J; Dobrev, D Challenges to the translation of basic science findings to atrial fibrillation therapies
FUTUR CARDIOL. 2016; 12(3): 251-254. Doi: 10.2217/fca-2016-0007
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** Heijman, J; Schirmer, I; Dobrev, D The multiple proarrhythmic roles of cardiac calcium-handling abnormalities: triggered activity, conduction abnormalities, beat-to-beat variability, and adverse remodelling
EUROPACE. 2016; 18(10): 1452-1454. Doi: 10.1093/europace/euv417
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2015

Originalarbeit (Zeitschrift)

** Schmidt, C; Wiedmann, F; Voigt, N; Zhou, XB; Heijman, J; Lang, S; Albert, V; Kallenberger, S; Ruhparwar, A; Szabó, G; Kallenbach, K; Karck, M; Borggrefe, M; Biliczki, P; Ehrlich, JR; Baczkó, I; Lugenbiel, P; Schweizer, PA; Donner, BC; Katus, HA; Dobrev, D; Thomas, D Upregulation of K2P3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation
CIRCULATION. 2015; 132(2): 82-92. Doi: 10.1161/CIRCULATIONAHA.114.012657
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Übersichtsarbeit

** Heijman, J; Voigt, N; Ghezelbash, S; Schirmer, I; Dobrev, D Calcium Handling Abnormalities as a Target for Atrial Fibrillation Therapeutics: How Close to Clinical Implementation?
J CARDIOVASC PHARM. 2015; 66(6): 515-522. Doi: 10.1097/FJC.0000000000000253
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** Voigt, N; Heijman, J; Dobrev, D New antiarrhythmic targets in atrial fibrillation
FUTUR CARDIOL. 2015; 11(6): 645-654. Doi: 10.2217/fca.15.67
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Editorial

** Heijman, J; Crijns, HJGM T-wave Right Slope Provides a New Angle in the Prediction of Drug-Induced Ventricular Arrhythmias
CARDIOVASC DRUG THER. 2015; 29(5): 411-413. Doi: 10.1007/s10557-015-6620-7
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** Heijman, J; Dobrev, D Irregular rhythm and atrial metabolism are key for the evolution of proarrhythmic atrial remodeling in atrial fibrillation
BASIC RES CARDIOL. 2015; 110(4): 41 Doi: 10.1007/s00395-015-0498-1
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** Heijman, J; Heusch, G; Dobrev, D Tools to Keep the Clock Ticking: Molecular Approaches to Treat Sinus Node Dysfunction
CARDIOLOGY. 2015; 132(1): 45-48. Doi: 10.1159/000430783
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2014

Originalarbeit (Zeitschrift)

** Heijman, J; Voigt, N; Carlsson, LG; Dobrev, D Cardiac safety assays
CURR OPIN PHARMACOL. 2014; 15: 16-21. Doi: 10.1016/j.coph.2013.11.004
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** Heijman, J; Voigt, N; Nattel, S; Dobrev, D Cellular and Molecular Electrophysiology of Atrial Fibrillation Initiation, Maintenance, and Progression
CIRC RES. 2014; 114(9): 1483-1499. Doi: 10.1161/CIRCRESAHA.114.302226
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** Spätjens, RLHMG; Bébarová, M; Seyen, SRM; Lentink, V; Jongbloed, RJ; Arens, YHJM; Heijman, J; Volders, PGA Long-QT mutation p.K557E-Kv7.1: dominant-negative suppression of IKs, but preserved cAMP-dependent up-regulation
CARDIOVASC RES. 2014; 104(1): 216-225. Doi: 10.1093/cvr/cvu191
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** Voigt, N; Heijman, J; Dobrev, D Cardiovascular pharmacotherapy
HERZ. 2014; 39(2): 227-238. Doi: 10.1007/s00059-014-4066-5
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** Voigt, N; Heijman, J; Wang, QL; Chiang, DY; Li, N; Karck, M; Wehrens, XHT; Nattel, S; Dobrev, D Cellular and Molecular Mechanisms of Atrial Arrhythmogenesis in Patients With Paroxysmal Atrial Fibrillation
CIRCULATION. 2014; 129(2): 145-156. Doi: 10.1161/CIRCULATIONAHA.113.006641
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Übersichtsarbeit

** Heijman, J; Voigt, N; Wehrens, XHT; Dobrev, D Calcium dysregulation in atrial fibrillation: the role of CaMKII
FRONT PHARMACOL. 2014; 5: 30 Doi: 10.3389/fphar.2014.00030
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** Voigt, N; Abu-Taha, I; Heijman, J; Dobrev, D Constitutive activity of the acetylcholine-activated potassium current IK,ACh in cardiomyocytes.
Adv Pharmacol. 2014; 70: 393-409. Doi: 10.1016/B978-0-12-417197-8.00013-4
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Editorial

** Heijman, J; Dobrev, D Rat engineered heart tissue: a novel tool in the safety pharmacology toolkit?
BASIC RES CARDIOL. 2014; 109(6): 437 Doi: 10.1007/s00395-014-0437-6
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2013

Originalarbeit (Zeitschrift)

** Heijman, J; Heusch, G; Dobrev, D Pleiotropic effects of antiarrhythmic agents: dronedarone in the treatment of atrial fibrillation.
Clin Med Insights Cardiol. 2013; 7: 127-40. Doi: 10.4137/CMC.S8445 [OPEN ACCESS]
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** Heijman, J; Voigt, N; Abu-Taha, IH; Dobrev, D Rhythm Control of Atrial Fibrillation in Heart Failure
HEART FAIL CLIN. 2013; 9(4): 407-+. Doi: 10.1016/j.hfc.2013.06.001
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** Heijman, J; Zaza, A; Johnson, DM; Rudy, Y; Peeters, RLM; Volders, PGA; Westra, RL Determinants of Beat-to-Beat Variability of Repolarization Duration in the Canine Ventricular Myocyte: A Computational Analysis
PLOS COMPUT BIOL. 2013; 9(8): e1003202 Doi: 10.1371/journal.pcbi.1003202
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** Johnson, DM; Heijman, J; Bode, EF; Greensmith, DJ; van der Linde, H; Abi-Gerges, N; Eisner, DA; Trafford, AW; Volders, PGA Diastolic Spontaneous Calcium Release From the Sarcoplasmic Reticulum Increases Beat-to-Beat Variability of Repolarization in Canine Ventricular Myocytes After β-Adrenergic Stimulation
CIRC RES. 2013; 112(2): 246-+. Doi: 10.1161/CIRCRESAHA.112.275735
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** Voigt, N; Heijman, J; Trausch, A; Mintert-Jancke, E; Pott, L; Ravens, U; Dobrev, D Impaired Na+-dependent regulation of acetylcholine-activated inward-rectifier K+ current modulates action potential rate dependence in patients with chronic atrial fibrillation
J MOL CELL CARDIOL. 2013; 61: 142-152. Doi: 10.1016/j.yjmcc.2013.03.011
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Übersichtsarbeit

** Heijman, J; Dewenter, M; El-Armouche, A; Dobrev, D Function and regulation of serine/threonine phosphatases in the healthy and diseased heart
J MOL CELL CARDIOL. 2013; 64: 90-98. Doi: 10.1016/j.yjmcc.2013.09.006
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** Heijman, J; Voigt, N; Dobrev, D New directions in antiarrhythmic drug therapy for atrial fibrillation.
Future Cardiol. 2013; 9(1): 71-88. Doi: 10.2217/fca.12.78
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** Tsuji, Y; Heijman, J; Nattel, S; Dobrev, D Electrical storm: recent pathophysiological insights and therapeutic consequences
BASIC RES CARDIOL. 2013; 108(2): 336 Doi: 10.1007/s00395-013-0336-2
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Editorial

** Heijman, J; Dobrev, D Pleiotropic actions of amiodarone: still puzzling after half a century
N-S ARCH PHARMACOL. 2013; 386(7): 571-574. Doi: 10.1007/s00210-013-0865-0
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** Heijman, J; Dobrev, D KCNQ1 autoantibodies: another way to regulate IKs
CARDIOVASC RES. 2013; 98(3): 329-331. Doi: 10.1093/cvr/cvt099
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** Heijman, J; Wehrens, XHT; Dobrev, D Atrial arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia - is there a mechanistic link between sarcoplasmic reticulum Ca2+ leak and re-entry?
ACTA PHYSIOL. 2013; 207(2): 208-211. Doi: 10.1111/apha.12038
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2012

Originalarbeit (Zeitschrift)

** Heijman, J; Spätjens, RLHMG; Seyen, SRM; Lentink, V; Kuijpers, HJH; Boulet, IR; de Windt, LJ; David, M; Volders, PGA Dominant-Negative Control of cAMP-Dependent IKs Upregulation in Human Long-QT Syndrome Type 1
CIRC RES. 2012; 110(2): 211-+. Doi: 10.1161/CIRCRESAHA.111.249482
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Übersichtsarbeit

** Heijman, J; Voigt, N; Nattel, S; Dobrev, D Calcium handling and atrial fibrillation.
Wien Med Wochenschr. 2012; 162(13-14): 287-91. Doi: 10.1007/s10354-012-0109-9
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Editorial

** Heijman, J; Dobrev, D Systems approaches to post-operative atrial fibrillation - Do they help us to better understand the ionic basis of the arrhythmogenic substrate?
J MOL CELL CARDIOL. 2012; 53(3): 320-322. Doi: 10.1016/j.yjmcc.2012.06.005
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2011

Originalarbeit (Zeitschrift)

** Heijman, J; Volders, PGA; Westra, RL; Rudy, Y Local control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca2+-transient
J MOL CELL CARDIOL. 2011; 50(5): 863-871. Doi: 10.1016/j.yjmcc.2011.02.007
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2010

Originalarbeit (Zeitschrift)

** Johnson, DM; Heijman, J; Pollard, CE; Valentin, JP; Crijns, HJGM; Abi-Gerges, N; Volders, PGA IKs restricts excessive beat-to-beat variability of repolarization during beta-adrenergic receptor stimulation
J MOL CELL CARDIOL. 2010; 48(1): 122-130. Doi: 10.1016/j.yjmcc.2009.08.033
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2009

Originalarbeit (Zeitschrift)

** Decker, KF; Heijman, J; Silva, JR; Hund, TJ; Rudy, Y Properties and ionic mechanisms of action potential adaptation, restitution, and accommodation in canine epicardium
AM J PHYSIOL-HEART C. 2009; 296(4): H1017-H1026. Doi: 10.1152/ajpheart.01216.2008
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