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Osto Elena |

Publications

** = Publications listed in SCI/SSCI/Pubmed

2025

Full paper/article (Journal)

** Wang, YJ; Gaul, DS; Gorica, E; Pahla, J; Wang, Z; Mohammed, SA; Dahlby, T; Dietrich, E; Osto, E; Gariani, K; Costantino, S; Winnik, S; Stein, S; Hazen, SL; Ruschitzka, F; Auwerx, J; Matter, CM NAD⁺ boosting increases atherosclerotic plaques and inflammation in Apoe knockout mice.
Atherosclerosis. 2025; 404:119188 Doi: 10.1016/j.atherosclerosis.2025.119188
Web of Science PubMed FullText FullText_MUG

** Weiser-Fuchs, MT; Jantscher, A; Tischler, S; Osto, E; Balayan, L; Scharnagl, H; Jäger, G; Amtmann, B; Kulovic-Sissawo, A; Puster, S; Fluhr, H; Obermayer-Pietsch, B; Stern, C; Hiden, U; Jantscher-Krenn, E Pregnancy shifts endothelial progenitor cell morphology and function: Role of metabolism, pro-inflammatory cytokines and fetal sex.
J Physiol. 2025; Doi: 10.1113/JP288038
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Review

** Kirsch, A; Gindlhuber, J; Zabini, D; Osto, E Bile acids and incretins as modulators of obesity-associated atherosclerosis
FRONT CARDIOVASC MED. 2025; 11: 1510148 Doi: 10.3389/fcvm.2024.1510148 [OPEN ACCESS]
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** Liberale, L; Tual-Chalot, S; Sedej, S; Ministrini, S; Georgiopoulos, G; Grunewald, M; Bäck, M; Bochaton-Piallat, ML; Boon, RA; Ramos, GC; de, Winther, MPJ; Drosatos, K; Evans, PC; Ferguson, JF; Forslund-Startceva, SK; Goettsch, C; Giacca, M; Haendeler, J; Kallikourdis, M; Ketelhuth, DFJ; Koenen, RR; Lacolley, P; Lutgens, E; Maffia, P; Miwa, S; Monaco, C; Montecucco, F; Norata, GD; Osto, E; Richardson, GD; Riksen, NP; Soehnlein, O; Spyridopoulos, I; Van, Linthout, S; Vilahur, G; Wentzel, JJ; Andrés, V; Badimon, L; Benetos, A; Binder, CJ; Brandes, RP; Crea, F; Furman, D; Gorbunova, V; Guzik, TJ; Hill, JA; Lüscher, TF; Mittelbrunn, M; Nencioni, A; Netea, MG; Passos, JF; Stamatelopoulos, KS; Tavernarakis, N; Ungvari, Z; Wu, JC; Kirkland, JL; Camici, GG; Dimmeler, S; Kroemer, G; Abdellatif, M; Stellos, K Roadmap for alleviating the manifestations of ageing in the cardiovascular system.
Nat Rev Cardiol. 2025; Doi: 10.1038/s41569-025-01130-5
Web of Science PubMed FullText FullText_MUG

2024

Full paper/article (Journal)

** Burrello, J; Goi, J; Burrello, A; Vacchi, E; Rendon-Angel, A; Lazzarini, E; Bianco, G; Limongelli, V; Vassalli, G; Cereda, CW; Monticone, S; Mulatero, P; Bussolati, B; Alimonti, A; Camici, GG; Melli, G; Osto, E; Pedrazzini, G; Lucio, B Age- and sex-related variations in extracellular vesicle profiling for the assessment of cardiovascular risk: the EVaging index.
NPJ Aging. 2024; 10(1): 63 Doi: 10.1038/s41514-024-00189-7 [OPEN ACCESS]
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** Delko, T; Kraljević, M; Lazaridis, II; Köstler, T; Jomard, A; Taheri, A; Lutz, TA; Osto, E; Zingg, U Laparoscopic Roux-Y-gastric bypass versus laparoscopic one-anastomosis gastric bypass for obesity: clinical & metabolic results of a prospective randomized controlled trial.
Surg Endosc. 2024; Doi: 10.1007/s00464-024-10907-7
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** Pirri, D; Tian, S; Tardajos-Ayllon, B; Irving, S; Donati, F; Allen, SP; Mammoto, T; Vilahur, G; Kabir, L; Bennett, J; Rasool, Y; Pericleous, C; Mazzei, G; McAllan, L; Scott, WR; Koestler, T; Zingg, U; Birdsey, G; Miller, C; Schenkel, T; Chambers, EV; Dunning, M; Serbanovic-Canic, J; Botrè, F; Mammoto, A; Xu, S; Osto, E; Han, W; Fragiadaki, M; Evans, PC EPAS1 Attenuates Atherosclerosis Initiation at Disturbed Flow Sites Through Endothelial Fatty Acid Uptake.
Circ Res. 2024; Doi: 10.1161/CIRCRESAHA.123.324054 [OPEN ACCESS]
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** Simonenko, M; Hansen, D; Niebauer, J; Volterrani, M; Adamopoulos, S; Amarelli, C; Ambrosetti, M; Anker, SD; Bayes-Genis, A; Ben, Gal, T; Bowen, TS; Cacciatore, F; Caminiti, G; Cavarretta, E; Chioncel, O; Coats, AJS; Cohen-Solal, A; D'Ascenzi, F; de, Pablo, Zarzosa, C; Gevaert, AB; Gustafsson, F; Kemps, H; Hill, L; Jaarsma, T; Jankowska, E; Joyce, E; Krankel, N; Lainscak, M; Lund, LH; Moura, B; Nytrøen, K; Osto, E; Piepoli, M; Potena, L; Rakisheva, A; Rosano, G; Savarese, G; Seferovic, PM; Thompson, DR; Thum, T; Van, Craenenbroeck, EM Prevention and Rehabilitation After Heart Transplantation: A Clinical Consensus Statement of the European Association of Preventive Cardiology, Heart Failure Association of the ESC, and the European Cardio Thoracic Transplant Association, a Section of ESOT.
Transpl Int. 2024; 37: 13191 Doi: 10.3389/ti.2024.13191 [OPEN ACCESS]
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** Simonenko, M; Hansen, D; Niebauer, J; Volterrani, M; Adamopoulos, S; Amarelli, C; Ambrosetti, M; Anker, SD; Bayes-Genis, A; Gal, TB; Bowen, TS; Cacciatore, F; Caminiti, G; Cavaretta, E; Chioncel, O; Coats, AJS; Cohen-Solal, A; D'Ascenzi, F; de, Pablo, Zarzosa, C; Gevaert, AB; Gustafsson, F; Kemps, H; Hill, L; Jaarsma, T; Jankowska, E; Joyce, E; Krankel, N; Lainscak, M; Lund, LH; Moura, B; Nytrøen, K; Osto, E; Piepoli, M; Potena, L; Rakisheva, A; Rosano, G; Savarese, G; Seferovic, PM; Thompson, DR; Thum, T; Van, Craenenbroeck, EM Prevention and rehabilitation after heart transplantation: A clinical consensus statement of the European Association of Preventive Cardiology, Heart Failure Association of the ESC, and the European Cardio Thoracic Transplant Association, a section of ESOT.
Eur J Prev Cardiol. 2024; Doi: 10.1093/eurjpc/zwae179
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** Simonenko, M; Hansen, D; Niebauer, J; Volterrani, M; Adamopoulos, S; Amarelli, C; Ambrosetti, M; Anker, SD; Bayes-Genis, A; Gal, TB; Bowen, TS; Cacciatore, F; Caminiti, G; Cavaretta, E; Chioncel, O; Coats, AJS; Cohen-Solal, A; D'Ascenzi, F; Zarzosa, CD; Gevaert, AB; Gustafsson, F; Kemps, H; Hill, L; Jaarsma, T; Jankowska, E; Joyce, E; Krankel, N; Lainscak, M; Lund, LH; Moura, B; Nytroen, K; Osto, E; Piepoli, M; Potena, L; Rakisheva, A; Rosano, G; Savarese, G; Seferovic, PM; Thompson, DR; Thum, T; Van Craenenbroeck, EM Prevention and rehabilitation after heart transplantation: A clinical consensus statement of the European Association of Preventive Cardiology, Heart Failure Association of the ESC, and the European Cardio Thoracic Transplant Association, a section of ESOT
EUR J HEART FAIL. 2024; Doi: 10.1002/ejhf.3185
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Review

** Madreiter-Sokolowski, CT; Hiden, U; Krstic, J; Panzitt, K; Wagner, M; Enzinger, C; Khalil, M; Abdellatif, M; Malle, E; Madl, T; Osto, E; Schosserer, M; Binder, CJ; Olschewski, A Targeting organ-specific mitochondrial dysfunction to improve biological aging.
Pharmacol Ther. 2024; 262:108710 Doi: 10.1016/j.pharmthera.2024.108710
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Abstract (Journal)

** Osto, E Vascular function in cardiometabolic disorders.
ACTA PHYSIOL. 2024; 240: 7-7.-XXIII FEPS Meeting; SEP 4-6, 2024; Granada,SPAIN;. [Keynote lecture]
Web of Science

Comment

** Kerkhof, PLM; Osto, E; Handly, N What characterizes device-related thrombosis following LAAC, if ejection fraction fails to shine?
ECHOCARDIOGR-J CARD. 2024; 41(8): e15902 Doi: 10.1111/echo.15902
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** Lutz, TA; Osto, E Deadly Sweet.
Eur J Prev Cardiol. 2024; Doi: 10.1093/eurjpc/zwae387
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2023

Full paper/article (Journal)

** Civieri, G; Masiero, G; Osto, E; Gambino, A; Angelini, A; Fraiese, A; Fedrigo, M; Toscano, G; Bottio, T; Perazzolo, Marra, M; Iliceto, S; Gerosa, G; Tona, F Coronary Collateral Circulation: A New Predictor of Mortality in Heart Transplant Recipients With Allograft Vasculopathy.
Transplant Direct. 2023; 9(5): e1470 Doi: 10.1097/TXD.0000000000001470 [OPEN ACCESS]
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** Guo, J; Qiu, J; Jia, M; Li, Q; Wei, X; Li, L; Pan, Q; Jin, J; Ge, F; Ma, S; He, Y; Lin, J; Li, Y; Ma, J; Jiang, N; Zhi, X; Jiang, L; Zhang, J; Osto, E; Jing, Q; Wang, X; Meng, D BACH1 deficiency prevents neointima formation and maintains the differentiated phenotype of vascular smooth muscle cells by regulating chromatin accessibility.
Nucleic Acids Res. 2023; 51(9):4284-4301 Doi: 10.1093/nar/gkad120 [OPEN ACCESS]
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** He, Y; Guo, J; Yu, Y; Jin, J; Jiang, Q; Li, Q; Ma, S; Pan, Q; Lin, J; Jiang, N; Ma, J; Li, Y; Hou, Y; Zhi, X; Jiang, L; Qu, L; Osto, E; Wang, X; Wei, X; Meng, D BACH1 regulates the differentiation of vascular smooth muscle cells from human embryonic stem cells via CARM1-mediated methylation of H3R17.
Cell Rep. 2023; 42(12): 113468 Doi: 10.1016/j.celrep.2023.113468
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** Huwiler, S; Carro-Domínguez, M; Stich, FM; Sala, R; Aziri, F; Trippel, A; Ryf, T; Markendorf, S; Niederseer, D; Bohm, P; Stoll, G; Laubscher, L; Thevan, J; Spengler, CM; Gawinecka, J; Osto, E; Huber, R; Wenderoth, N; Schmied, C; Lustenberger, C Auditory stimulation of sleep slow waves enhances left ventricular function in humans.
Eur Heart J. 2023; 44(40): 4288-4291. Doi: 10.1093/eurheartj/ehad630 [OPEN ACCESS]
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** Jin, J; He, Y; Guo, J; Pan, Q; Wei, X; Xu, C; Qi, Z; Li, Q; Ma, S; Lin, J; Jiang, N; Ma, J; Wang, X; Jiang, L; Ding, Q; Osto, E; Zhi, X; Meng, D BACH1 controls hepatic insulin signaling and glucose homeostasis in mice.
Nat Commun. 2023; 14(1): 8428 Doi: 10.1038/s41467-023-44088-z [OPEN ACCESS]
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** Osto, E; Bonacina, F; Pirillo, A; Norata, GD Neutral effect of SGLT2 inhibitors on lipoprotein metabolism: From clinical evidence to molecular mechanisms.
Pharmacol Res. 2023; 188: 106667 Doi: 10.1016/j.phrs.2023.106667
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** Pedretti, RFE; Hansen, D; Ambrosetti, M; Back, M; Berger, T; Ferreira, MC; Cornelissen, V; Davos, CH; Doehner, W; de, Pablo, Y, Zarzosa, C; Frederix, I; Greco, A; Kurpas, D; Michal, M; Osto, E; Pedersen, SS; Salvador, RE; Simonenko, M; Steca, P; Thompson, DR; Wilhelm, M; Abreu, A How to optimize the adherence to a guideline-directed medical therapy in the secondary prevention of cardiovascular diseases: a clinical consensus statement from the European Association of Preventive Cardiology.
Eur J Prev Cardiol. 2023; 30(2): 149-166. Doi: 10.1093/eurjpc/zwac204
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** Stellato, M; Dewenter, M; Rudnik, M; Hukara, A; Özsoy, Ç; Renoux, F; Pachera, E; Gantenbein, F; Seebeck, P; Uhtjaerv, S; Osto, E; Razansky, D; Klingel, K; Henes, J; Distler, O; Błyszczuk, P; Kania, G The AP-1 transcription factor Fosl-2 drives cardiac fibrosis and arrhythmias under immunofibrotic conditions.
Commun Biol. 2023; 6(1): 161 Doi: 10.1038/s42003-023-04534-6 [OPEN ACCESS]
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** Wei, X; Jin, J; Wu, J; He, Y; Guo, J; Yang, Z; Chen, L; Hu, K; Li, L; Jia, M; Li, Q; Lv, X; Ge, F; Ma, S; Wu, H; Zhi, X; Wang, X; Jiang, L; Osto, E; Zhang, J; Meng, D Cardiac-specific BACH1 ablation attenuates pathological cardiac hypertrophy by inhibiting the Ang II type 1 receptor expression and the Ca2+/CaMKII pathway.
Cardiovasc Res. 2023; 119(9): 1842-1855. Doi: 10.1093/cvr/cvad086
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Review

** de, Winther, MPJ; Bäck, M; Evans, P; Gomez, D; Goncalves, I; Jørgensen, HF; Koenen, RR; Lutgens, E; Norata, GD; Osto, E; Dib, L; Simons, M; Stellos, K; Ylä-Herttuala, S; Winkels, H; Bochaton-Piallat, ML; Monaco, C Translational opportunities of single-cell biology in atherosclerosis.
Eur Heart J. 2023; 44(14): 1216-1230. Doi: 10.1093/eurheartj/ehac686 [OPEN ACCESS]
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Editorial

** Osto, E; Roeters, van, Lennep, JE; Tokgözoğlu, L; Öörni, K Influence of sex and gender on the biology of atherosclerotic cardiovascular disease: Special issue.
Atherosclerosis. 2023; 384: 117297 Doi: 10.1016/j.atherosclerosis.2023.117297
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Correction

** Stellato, M; Dewenter, M; Rudnik, M; Hukara, A; Özsoy, Ç; Renoux, F; Pachera, E; Gantenbein, F; Seebeck, P; Uhtjaerv, S; Osto, E; Razansky, D; Klingel, K; Henes, J; Distler, O; Błyszczuk, P; Kania, G Author Correction: The AP-1 transcription factor Fosl-2 drives cardiac fibrosis and arrhythmias under immunofibrotic conditions.
Commun Biol. 2023; 6(1): 213 Doi: 10.1038/s42003-023-04600-z [OPEN ACCESS]
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News-Item

** Lutgens, E; Osto, E; Bochaton-Piallat, ML The European Society of Cardiology working group on atherosclerosis and vascular biology.
Eur Heart J. 2023; Doi: 10.1093/eurheartj/ehad536
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2022

Full paper/article (Journal)

** Cecere, A; Kerkhof, PLM; Civieri, G; Angelini, A; Gambino, A; Fraiese, A; Bottio, T; Osto, E; Famoso, G; Fedrigo, M; Giacomin, E; Toscano, G; Montisci, R; Iliceto, S; Gerosa, G; Tona, F Coronary Flow Evaluation in Heart Transplant Patients Compared to Healthy Controls Documents the Superiority of Coronary Flow Velocity Reserve Companion as Diagnostic and Prognostic Tool.
Front Cardiovasc Med. 2022; 9: 887370 Doi: 10.3389/fcvm.2022.887370 [OPEN ACCESS]
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** Jia, M; Li, Q; Guo, J; Shi, W; Zhu, L; Huang, Y; Li, Y; Wang, L; Ma, S; Zhuang, T; Wang, X; Pan, Q; Wei, X; Qin, Y; Li, X; Jin, J; Zhi, X; Tang, J; Jing, Q; Li, S; Jiang, L; Qu, L; Osto, E; Zhang, J; Wang, X; Yu, B; Meng, D Deletion of BACH1 Attenuates Atherosclerosis by Reducing Endothelial Inflammation.
Circ Res. 2022; 130(7): 1038-1055. Doi: 10.1161/CIRCRESAHA.121.319540
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** Jomard, A; Liberale, L; Doytcheva, P; Reiner, MF; Müller, D; Visentin, M; Bueter, M; Lüscher, TF; Vettor, R; Lutz, TA; Camici, GG; Osto, E Effects of acute administration of trimethylamine N-oxide on endothelial function: a translational study.
Sci Rep. 2022; 12(1): 8664 Doi: 10.1038/s41598-022-12720-5 [OPEN ACCESS]
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** Koskinas, KC; Dendale, P; Halle, M; Caselli, S; Cornelissen, V; Kavousi, M; Kurpas, D; Osto, E; Raupach, T; Semb, AG; Pedretti, RFE Introducing the new Task Force on Cardiovascular Risk Factors of the European Association of Preventive Cardiology.
Eur J Prev Cardiol. 2022; 29(13): 1718-1720. Doi: 10.1093/eurjpc/zwac118
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** Sudano, I; Osto, E; Ruschitzka, F Blood Pressure-Lowering Therapy.
Handb Exp Pharmacol. 2022; 270: 25-45. Doi: 10.1007/164_2020_372
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** Tona, F; Osto, E; Kerkhof, PLM; Montisci, R; Famoso, G; Lorenzoni, G; De, Michieli, L; Cecere, A; Zanetti, I; Civieri, G; Iliceto, S; Piaserico, S Multiparametric analysis of coronary flow in psoriasis using a coronary flow reserve companion.
Eur J Clin Invest. 2022; 52(4): e13711 Doi: 10.1111/eci.13711 [OPEN ACCESS]
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Review

** Dietrich, E; Jomard, A; Osto, E Crosstalk between high-density lipoproteins and endothelial cells in health and disease: Insights into sex-dependent modulation.
Front Cardiovasc Med. 2022; 9: 989428 Doi: 10.3389/fcvm.2022.989428 [OPEN ACCESS]
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** Evans, PC; Davidson, SM; Wojta, J; Bäck, M; Bollini, S; Brittan, M; Catapano, AL; Chaudhry, B; Cluitmans, M; Gnecchi, M; Guzik, TJ; Hoefer, I; Madonna, R; Monteiro, JP; Morawietz, H; Osto, E; Padró, T; Sluimer, JC; Tocchetti, CG; Van, der, Heiden, K; Vilahur, G; Waltenberger, J; Weber, C From novel discovery tools and biomarkers to precision medicine-basic cardiovascular science highlights of 2021/22.
Cardiovasc Res. 2022; 118(13): 2754-2767. Doi: 10.1093/cvr/cvac114 [OPEN ACCESS]
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** Gevaert, AB; Wood, N; Boen, JRA; Davos, CH; Hansen, D; Hanssen, H; Krenning, G; Moholdt, T; Osto, E; Paneni, F; Pedretti, RFE; Plösch, T; Simonenko, M; Bowen, TS Epigenetics in the primary and secondary prevention of cardiovascular disease: influence of exercise and nutrition.
Eur J Prev Cardiol. 2022; 29(17): 2183-2199. Doi: 10.1093/eurjpc/zwac179
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Correction

** Sudano, I; Osto, E; Ruschitzka, F Correction to: Blood Pressure-Lowering Therapy.
Handb Exp Pharmacol. 2022; 270: 537-538. Doi: 10.1007/164_2020_410
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Comment

** Osto, E The promise of the gut metabolite propionate for a novel and personalized lipid-lowering treatment.
Eur Heart J. 2022; 43(6): 534-537. Doi: 10.1093/eurheartj/ehab723 [OPEN ACCESS]
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2021

Full paper/article (Journal)

** Bengs, S; Haider, A; Warnock, GI; Fiechter, M; Pargaetzi, Y; Rampidis, G; Etter, D; Wijnen, WJ; Portmann, A; Osto, E; Treyer, V; Benz, DC; Meisel, A; Fuchs, TA; Gräni, C; Buechel, RR; Kaufmann, PA; Pazhenkottil, AP; Gebhard, C Quantification of perivascular inflammation does not provide incremental prognostic value over myocardial perfusion imaging and calcium scoring.
Eur J Nucl Med Mol Imaging. 2021; 48(6):1806-1812 Doi: 10.1007/s00259-020-05106-0 [OPEN ACCESS]
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** Bonetti, NR; Liberale, L; Akhmedov, A; Pasterk, L; Gobbato, S; Puspitasari, YM; Vukolic, A; Saeedi, Saravi, SS; Coester, B; Horvath, C; Osto, E; Montecucco, F; Lüscher, TF; Beer, JH; Camici, GG Long-term dietary supplementation with plant-derived omega-3 fatty acid improves outcome in experimental ischemic stroke.
Atherosclerosis. 2021; 325:89-98 Doi: 10.1016/j.atherosclerosis.2021.04.005
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** Ge, F; Pan, Q; Qin, Y; Jia, M; Ruan, C; Wei, X; Jing, Q; Zhi, X; Wang, X; Jiang, L; Osto, E; Guo, J; Meng, D Single-Cell Analysis Identify Transcription Factor BACH1 as a Master Regulator Gene in Vascular Cells During Aging.
Front Cell Dev Biol. 2021; 9: 786496 Doi: 10.3389/fcell.2021.786496 [OPEN ACCESS]
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Review

** Alexander, Y; Osto, E; Schmidt-Trucksäss, A; Shechter, M; Trifunovic, D; Duncker, DJ; Aboyans, V; Bäck, M; Badimon, L; Cosentino, F; De, Carlo, M; Dorobantu, M; Harrison, DG; Guzik, TJ; Hoefer, I; Morris, PD; Norata, GD; Suades, R; Taddei, S; Vilahur, G; Waltenberger, J; Weber, C; Wilkinson, F; Bochaton-Piallat, ML; Evans, PC Endothelial function in cardiovascular medicine: a consensus paper of the European Society of Cardiology Working Groups on Atherosclerosis and Vascular Biology, Aorta and Peripheral Vascular Diseases, Coronary Pathophysiology and Microcirculation, and Thrombosis.
Cardiovasc Res. 2021; 117(1):29-42 Doi: 10.1093/cvr/cvaa085 [OPEN ACCESS]
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** Robert, J; Osto, E; von, Eckardstein, A The Endothelium Is Both a Target and a Barrier of HDL's Protective Functions.
Cells. 2021; 10(5): Doi: 10.3390/cells10051041 [OPEN ACCESS]
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2020

Full paper/article (Journal)

** Oppi, S; Nusser-Stein, S; Blyszczuk, P; Wang, X; Jomard, A; Marzolla, V; Yang, K; Velagapudi, S; Ward, LJ; Yuan, XM; Geiger, MA; Guillaumon, AT; Othman, A; Hornemann, T; Rancic, Z; Ryu, D; Oosterveer, MH; Osto, E; Lüscher, TF; Stein, S Macrophage NCOR1 protects from atherosclerosis by repressing a pro-atherogenic PPARγ signature.
Eur Heart J. 2020; 41(9):995-1005 Doi: 10.1093/eurheartj/ehz667
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** Osto, E A portrait of the ESC Working Group Atherosclerosis and Vascular Biology.
Eur Heart J. 2020; 41(24):2233-2235 Doi: 10.1093/eurheartj/ehaa304
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Review

** Evans, PC; Rainger, GE; Mason, JC; Guzik, TJ; Osto, E; Stamataki, Z; Neil, D; Hoefer, IE; Fragiadaki, M; Waltenberger, J; Weber, C; Bochaton-Piallat, ML; Bäck, M Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic Cardiovascular Science.
Cardiovasc Res. 2020; 116(14):2177-2184 Doi: 10.1093/cvr/cvaa230 [OPEN ACCESS]
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** Haider, A; Bengs, S; Luu, J; Osto, E; Siller-Matula, JM; Muka, T; Gebhard, C Sex and gender in cardiovascular medicine: presentation and outcomes of acute coronary syndrome.
Eur Heart J. 2020; 41(13):1328-1336 Doi: 10.1093/eurheartj/ehz898
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** Jomard, A; Osto, E High Density Lipoproteins: Metabolism, Function, and Therapeutic Potential.
Front Cardiovasc Med. 2020; 7:39 Doi: 10.3389/fcvm.2020.00039 [OPEN ACCESS]
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Abstract (Proceedings)

** Jomard, A; Chavez-Talavera, O; Doytcheva, P; Tailleux, A; Wolfrum, C; Lutz, T; Ruschitzka, F; von, Eckardstein, A; Staels, B; Osto, E Best Poster Award - Second Prize: Bile Acids as Novel Vascular Signalling Molecules and Therapeutic Target.
Eur Cardiol. European Cardiology Review 2020. 2020; 15: e25--24th Annual Scientific Meeting of the International Society of Cardiovascular Pharmacotherapy; MAY 9-10, 2019; Lugano, Switzerland. Doi: 10.15420/ecr.2020.15.1.PO2 [Poster] [OPEN ACCESS]
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2019

Full paper/article (Journal)

** Haider, A; Possner, M; Messerli, M; Bengs, S; Osto, E; Maredziak, M; Portmann, A; Fiechter, M; Giannopoulos, AA; Treyer, V; Gaisl, T; von, Felten, E; Patriki, D; Benz, DC; Fuchs, TA; Gräni, C; Pazhenkottil, AP; Buechel, RR; Kaufmann, PA; Gebhard, C Quantification of intrathoracic fat adds prognostic value in women undergoing myocardial perfusion imaging.
Int J Cardiol. 2019; 292:258-264 Doi: 10.1016/j.ijcard.2019.04.092
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** Kerkhof, PLM; Osto, E; Tona, F; Heyndrickx, GR; Handly, N Sex-Specific Interpretation of Coronary Flow Reserve and Fractional Flow Reserve Metrics, Including Their Companions.
Annu Int Conf IEEE Eng Med Biol Soc. 2019; 2019: 7006-7009. Doi: 10.1109/EMBC.2019.8857589
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** Piaserico, S; Osto, E; Famoso, G; Montisci, R; De, Michieli, L; Zanetti, I; Iliceto, S; Tona, F Long-term prognostic value of coronary flow reserve in psoriasis patients.
Atherosclerosis. 2019; 289:57-63 Doi: 10.1016/j.atherosclerosis.2019.08.009
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Review

** Dal, Lin, C; Tona, F; Osto, E The crosstalk between the cardiovascular and the immune system.
Vasc Biol. 2019; 1(1): H83-H88. Doi: 10.1530/VB-19-0023 [OPEN ACCESS]
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** Jomard, A; Osto, E [Metabolism and Function of High-Density Lipoproteins (HDL)].
Praxis (Bern 1994). 2019; 108(7): 477-486. Doi: 10.1024/1661-8157/a003241
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2018

Full paper/article (Journal)

** Kerkhof, PLM; Osto, E Women and Men in the History of Western Cardiology: Some Notes on Their Position as Patients, Role as Investigational Study Subjects, and Impact as Professionals.
Adv Exp Med Biol. 2018; 1065:1-30 Doi: 10.1007/978-3-319-77932-4_1
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** Tellatin, S; Maffei, P; Osto, E; Dassie, F; Famoso, G; Montisci, R; Martini, C; Fallo, F; Marra, MP; Mioni, R; Iliceto, S; Vettor, R; Tona, F Coronary microvascular dysfunction may be related to IGF-1 in acromegalic patients and can be restored by therapy.
Atherosclerosis. 2018; 269:100-105 Doi: 10.1016/j.atherosclerosis.2017.12.019
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Review

** Dal, Lin, C; Tona, F; Osto, E The Heart as a Psychoneuroendocrine and Immunoregulatory Organ.
Adv Exp Med Biol. 2018; 1065:225-239 Doi: 10.1007/978-3-319-77932-4_15
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** Previato, M; Osto, E; Kerkhof, PLM; Parry, G; Tona, F Heart Transplantation Survival and Sex-Related Differences.
Adv Exp Med Biol. 2018; 1065:379-388 Doi: 10.1007/978-3-319-77932-4_24
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2017

Full paper/article (Journal)

** Blyszczuk, P; Müller-Edenborn, B; Valenta, T; Osto, E; Stellato, M; Behnke, S; Glatz, K; Basler, K; Lüscher, TF; Distler, O; Eriksson, U; Kania, G Transforming growth factor-β-dependent Wnt secretion controls myofibroblast formation and myocardial fibrosis progression in experimental autoimmune myocarditis.
Eur Heart J. 2017; 38(18):1413-1425 Doi: 10.1093/eurheartj/ehw116
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** Doytcheva, P; Bächler, T; Tarasco, E; Marzolla, V; Engeli, M; Pellegrini, G; Stivala, S; Rohrer, L; Tona, F; Camici, GG; Vanhoutte, PM; Matter, CM; Lutz, TA; Lüscher, TF; Osto, E Inhibition of Vascular c-Jun N-Terminal Kinase 2 Improves Obesity-Induced Endothelial Dysfunction After Roux-en-Y Gastric Bypass.
J Am Heart Assoc. 2017; 6(11): Doi: 10.1161/JAHA.117.006441 [OPEN ACCESS]
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** Kraljević, M; Delko, T; Köstler, T; Osto, E; Lutz, T; Thommen, S; Droeser, RA; Rothwell, L; Oertli, D; Zingg, U Laparoscopic Roux-en-Y gastric bypass versus laparoscopic mini gastric bypass in the treatment of obesity: study protocol for a randomized controlled trial.
Trials. 2017; 18(1):226 Doi: 10.1186/s13063-017-1957-9 [OPEN ACCESS]
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** Simic, B; Mocharla, P; Crucet, M; Osto, E; Kratzer, A; Stivala, S; Kühnast, S; Speer, T; Doycheva, P; Princen, HM; van, der, Hoorn, JW; Jukema, JW; Giral, H; Tailleux, A; Landmesser, U; Staels, B; Lüscher, TF Anacetrapib, but not evacetrapib, impairs endothelial function in CETP-transgenic mice in spite of marked HDL-C increase.
Atherosclerosis. 2017; 257:186-194 Doi: 10.1016/j.atherosclerosis.2017.01.011
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2016

Full paper/article (Journal)

** Müller-Edenborn, B; Kania, G; Osto, E; Jakob, P; Krasniqi, N; Beck-Schimmer, B; Blyszczuk, P; Eriksson, U Lidocaine Enhances Contractile Function of Ischemic Myocardial Regions in Mouse Model of Sustained Myocardial Ischemia.
PLoS One. 2016; 11(5):e0154699 Doi: 10.1371/journal.pone.0154699 [OPEN ACCESS]
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** Piaserico, S; Osto, E; Famoso, G; Zanetti, I; Gregori, D; Poretto, A; Iliceto, S; Peserico, A; Tona, F Treatment with tumor necrosis factor inhibitors restores coronary microvascular function in young patients with severe psoriasis.
Atherosclerosis. 2016; 251:25-30 Doi: 10.1016/j.atherosclerosis.2016.05.036
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** Spinelli, V; Lalloyer, F; Baud, G; Osto, E; Kouach, M; Daoudi, M; Vallez, E; Raverdy, V; Goossens, JF; Descat, A; Doytcheva, P; Hubert, T; Lutz, TA; Lestavel, S; Staels, B; Pattou, F; Tailleux, A Influence of Roux-en-Y gastric bypass on plasma bile acid profiles: a comparative study between rats, pigs and humans.
Int J Obes (Lond). 2016; 40(8):1260-7 Doi: 10.1038/ijo.2016.46
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Review

** Lutz, TA; Osto, E Glucagon-like peptide-1, glucagon-like peptide-2, and lipid metabolism.
Curr Opin Lipidol. 2016; 27(3):257-63 Doi: 10.1097/MOL.0000000000000293
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2015

Full paper/article (Journal)

** Osto, E; Doytcheva, P; Corteville, C; Bueter, M; Dörig, C; Stivala, S; Buhmann, H; Colin, S; Rohrer, L; Hasballa, R; Tailleux, A; Wolfrum, C; Tona, F; Manz, J; Vetter, D; Spliethoff, K; Vanhoutte, PM; Landmesser, U; Pattou, F; Staels, B; Matter, CM; Lutz, TA; Lüscher, TF Rapid and body weight-independent improvement of endothelial and high-density lipoprotein function after Roux-en-Y gastric bypass: role of glucagon-like peptide-1.
Circulation. 2015; 131(10):871-81 Doi: 10.1161/CIRCULATIONAHA.114.011791
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** Tona, F; Osto, E; Famoso, G; Previato, M; Fedrigo, M; Vecchiati, A; Perazzolo, Marra, M; Tellatin, S; Bellu, R; Tarantini, G; Feltrin, G; Angelini, A; Thiene, G; Gerosa, G; Iliceto, S Coronary microvascular dysfunction correlates with the new onset of cardiac allograft vasculopathy in heart transplant patients with normal coronary angiography.
Am J Transplant. 2015; 15(5):1400-6 Doi: 10.1111/ajt.13108
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** Vianello, F; Cella, G; Osto, E; Ballin, A; Famoso, G; Tellatin, S; Iliceto, S; Cucchini, U; Saggiorato, G; Omenetto, E; Tona, F Coronary microvascular dysfunction due to essential thrombocythemia and policythemia vera: the missing piece in the puzzle of their increased cardiovascular risk?
Am J Hematol. 2015; 90(2):109-13 Doi: 10.1002/ajh.23881
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Review

** Dal, Lin, C; Tona, F; Osto, E Coronary Microvascular Function and Beyond: The Crosstalk between Hormones, Cytokines, and Neurotransmitters.
Int J Endocrinol. 2015; 2015:312848 Doi: 10.1155/2015/312848 [OPEN ACCESS]
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2014

Full paper/article (Journal)

** Tona, F; Serra, R; Di, Ascenzo, L; Osto, E; Scarda, A; Fabris, R; Montisci, R; Famoso, G; Tellatin, S; Foletto, M; Giovagnoni, A; Iliceto, S; Vettor, R Systemic inflammation is related to coronary microvascular dysfunction in obese patients without obstructive coronary disease.
Nutr Metab Cardiovasc Dis. 2014; 24(4):447-53 Doi: 10.1016/j.numecd.2013.09.021
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2013

Full paper/article (Journal)

** Paneni, F; Osto, E; Costantino, S; Mateescu, B; Briand, S; Coppolino, G; Perna, E; Mocharla, P; Akhmedov, A; Kubant, R; Rohrer, L; Malinski, T; Camici, GG; Matter, CM; Mechta-Grigoriou, F; Volpe, M; Lüscher, TF; Cosentino, F Deletion of the activated protein-1 transcription factor JunD induces oxidative stress and accelerates age-related endothelial dysfunction.
Circulation. 2013; 127(11):1229-40, e1-21 Doi: 10.1161/CIRCULATIONAHA.112.000826
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2012

Full paper/article (Journal)

** Osto, E; Fallo, F; Pelizzo, MR; Maddalozzo, A; Sorgato, N; Corbetti, F; Montisci, R; Famoso, G; Bellu, R; Lüscher, TF; Iliceto, S; Tona, F Coronary microvascular dysfunction induced by primary hyperparathyroidism is restored after parathyroidectomy.
Circulation. 2012; 126(9):1031-9 Doi: 10.1161/CIRCULATIONAHA.111.081307
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** Osto, E; Piaserico, S; Maddalozzo, A; Forchetti, G; Montisci, R; Famoso, G; Giovagnoni, A; Peserico, A; Iliceto, S; Tona, F Impaired coronary flow reserve in young patients affected by severe psoriasis.
Atherosclerosis. 2012; 221(1):113-7 Doi: 10.1016/j.atherosclerosis.2011.12.015
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** Paneni, F; Mocharla, P; Akhmedov, A; Costantino, S; Osto, E; Volpe, M; Lüscher, TF; Cosentino, F Gene silencing of the mitochondrial adaptor p66(Shc) suppresses vascular hyperglycemic memory in diabetes.
Circ Res. 2012; 111(3):278-89 Doi: 10.1161/CIRCRESAHA.112.266593
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2011

Full paper/article (Journal)

** Osto, E; Castellani, C; Fadini, GP; Baesso, I; Gambino, A; Agostini, C; Avogaro, A; Gerosa, G; Thiene, G; Iliceto, S; Angelini, A; Tona, F Impaired endothelial progenitor cell recruitment may contribute to heart transplant microvasculopathy.
J Heart Lung Transplant. 2011; 30(1):70-6 Doi: 10.1016/j.healun.2010.07.004
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2010

Full paper/article (Journal)

** Tarantini, G; Napodano, M; Gasparetto, N; Favaretto, E; Marra, MP; Cacciavillani, L; Bilato, C; Osto, E; Cademartiri, F; Musumeci, G; Corbetti, F; Razzolini, R; Iliceto, S Impact of multivessel coronary artery disease on early ischemic injury, late clinical outcome, and remodeling in patients with acute myocardial infarction treated by primary coronary angioplasty.
Coron Artery Dis. 2010; 21(2):78-86 Doi: 10.1097/MCA.0b013e328335a074
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** Tona, F; Osto, E; Tarantini, G; Gambino, A; Cavallin, F; Feltrin, G; Montisci, R; Caforio, AL; Gerosa, G; Iliceto, S Coronary flow reserve by transthoracic echocardiography predicts epicardial intimal thickening in cardiac allograft vasculopathy.
Am J Transplant. 2010; 10(7):1668-76 Doi: 10.1111/j.1600-6143.2010.03160.x
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Review

** Osto, E; Tona, F; De, Bon, E; Iliceto, S; Cella, G Endothelial dysfunction in cardiac allograft vasculopathy: potential pharmacological interventions.
Curr Vasc Pharmacol. 2010; 8(2):169-88 Doi: 10.2174/157016110790886992
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2009

Full paper/article (Journal)

** Osto, E; Tona, F; Angelini, A; Montisci, R; Ruscazio, M; Vinci, A; Tarantini, G; Ramondo, A; Gambino, A; Thiene, G; Caforio, AL; Gerosa, G; Iliceto, S Determinants of coronary flow reserve in heart transplantation: a study performed with contrast-enhanced echocardiography.
J Heart Lung Transplant. 2009; 28(5):453-60 Doi: 10.1016/j.healun.2009.02.008
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2008

Full paper/article (Journal)

** Delli, Gatti, C; Osto, E; Kouroedov, A; Eto, M; Shaw, S; Volpe, M; Lüscher, TF; Cosentino, F Pulsatile stretch induces release of angiotensin II and oxidative stress in human endothelial cells: effects of ACE inhibition and AT1 receptor antagonism.
Clin Exp Hypertens. 2008; 30(7):616-27 Doi: 10.1080/10641960802443183
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** Osto, E; Kouroedov, A; Mocharla, P; Akhmedov, A; Besler, C; Rohrer, L; von, Eckardstein, A; Iliceto, S; Volpe, M; Lüscher, TF; Cosentino, F Inhibition of protein kinase Cbeta prevents foam cell formation by reducing scavenger receptor A expression in human macrophages.
Circulation. 2008; 118(21):2174-82 Doi: 10.1161/CIRCULATIONAHA.108.789537
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** Osto, E; Matter, CM; Kouroedov, A; Malinski, T; Bachschmid, M; Camici, GG; Kilic, U; Stallmach, T; Boren, J; Iliceto, S; Lüscher, TF; Cosentino, F c-Jun N-terminal kinase 2 deficiency protects against hypercholesterolemia-induced endothelial dysfunction and oxidative stress.
Circulation. 2008; 118(20):2073-80 Doi: 10.1161/CIRCULATIONAHA.108.765032
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2007

Review

** Cosentino, F; Osto, E Aging and endothelial dysfunction.
Clin Hemorheol Microcirc. 2007; 37(1-2):143-7
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** Osto, E; Coppolino, G; Volpe, M; Cosentino, F Restoring the dysfunctional endothelium.
Curr Pharm Des. 2007; 13(10):1053-68 Doi: 10.2174/138161207780487566
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