Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Osto Elena |

** = Publikationen gelistet in SCI/SSCI/Pubmed

2025

Originalarbeit (Zeitschrift)

** Burrello, J; Gonzalez, Melo, M; Taheri, A; Nagler, M; Airale, L; Burrello, A; Goi, J; Kraljević, M; Tarik, D; Dietrich, E; Koestler, T; Mattiello, D; Zingg, U; Lutz, TA; Barile, L; Osto, E Extracellular vesicle signature is associated with cardio-metabolic improvement after bariatric surgery.
Eur J Prev Cardiol. 2025; Doi: 10.1093/eurjpc/zwaf561
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** Conte, E; Perone, F; Cosyns, B; Dweck, MR; Donal, E; Goncalves, I; Ibanez, B; Kaski, JC; Maurovich-Horvat, P; Onuma, Y; Osto, E; Bittencourt, MS; Serruys, PW; Andreini, D Therapies leading to coronary atherosclerosis plaque regression: a scientific statement of the European Association of Preventive Cardiology, the European Association of Cardiovascular Imaging of the ESC, the ESC Working Group on Atherosclerosis and Vascular Biology, and the ESC Working Group on Cardiovascular Pharmacotherapy Part 1: Atherosclerosis Pathophysiology and Imaging Evaluation
EUR J PREV CARDIOL. 2025; Doi: 10.1093/eurjpc/zwaf594
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** Conte, E; Perone, F; Cosyns, B; Dweck, MR; Donal, E; Goncalves, I; Ibanez, B; Kaski, JC; Maurovich-Horvat, P; Onuma, Y; Osto, E; Bittencourt, MS; Serruys, PW; Andreini, D Therapies leading to coronary atherosclerosis plaque regression: a scientific statement of the European Association of Preventive Cardiology, the European Association of Cardiovascular Imaging of the ESC, the ESC Working Group on Atherosclerosis and Vascular Biology, and the ESC Working Group on Cardiovascular Pharmacotherapy Part 2-drugs' specific effect on atherosclerosis
EUR J PREV CARDIOL. 2025; Doi: 10.1093/eurjpc/zwaf654
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** Lin, J; Liu, X; Li, Q; Ge, F; Ma, J; Ng, X; Pan, Q; Wei, X; Jiang, Q; Jin, J; Ma, S; He, Y; Li, Y; Jiang, N; Hou, Y; Yu, Y; Lin, X; Jin, Q; Xu, C; Wang, X; Zhi, X; Liang, Q; Jiang, L; Osto, E; Guo, J; Wang, XJ; Meng, D A BACH1 Inhibitor Ameliorates Myocardial Infarction and Limb Ischemia in Mice.
Mol Ther. 2025; Doi: 10.1016/j.ymthe.2025.07.008
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** Pedretti, RFE; Asteggiano, R; Gevaert, AB; Bowen, TS; Caselli, S; Cornelissen, VA; Christodorescu, R; Derosa, G; Dievart, F; Kurpas, D; Osto, E; Richter, D; Semb, AG; Steca, P; Guasti, L; Ferrini, M Cardiovascular risk factors management in older adults: a clinical consensus statement from the European Association of Preventive Cardiology of the ESC and the ESC Council for Cardiology Practice
EUR J PREV CARDIOL. 2025; Doi: 10.1093/eurjpc/zwaf175
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** Wang, YJ; Gaul, DS; Gorica, E; Pahla, J; Wang, Z; Mohammed, SA; Dahlby, T; Dietrich, E; Osto, E; Gariani, K; Costantino, S; Winnik, S; Stein, S; Hazen, SL; Ruschitzka, F; Auwerx, J; Matter, CM NAD+ boosting increases atherosclerotic plaques and inflammation in Apoe knockout mice.
Atherosclerosis. 2025; 404:119188 Doi: 10.1016/j.atherosclerosis.2025.119188 [OPEN ACCESS]
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** Weiser-Fuchs, MT; Jantscher, A; Tischler, S; Osto, E; Balayan, L; Scharnagl, H; Jäger, G; Amtmann, B; Kulovic-Sissawo, A; Puster, S; Fluhr, H; Obermayer-Pietsch, B; Stern, C; Hiden, U; Jantscher-Krenn, E Pregnancy shifts endothelial progenitor cell morphology and function: Role of metabolism, pro-inflammatory cytokines and fetal sex.
J Physiol. 2025; Doi: 10.1113/JP288038
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Kurzbericht/Letter

** Glatz, U; Müller, A; Moser, O; Aberer, F; Niedrist, T; Herrmann, M; Zelzer, S; Jaruan, O; Sourij, C; Osto, E; Oettl, K; Paar, M; Pieber, T; Pferschy, P; Tripolt, N; Aziz, F; Sourij, H Acute and prolonged effects of aerobic endurance training on N-lactoyl-phenylalanine and inflammatory markers in individuals with type 1 diabetes: An exploratory analysis of the ULTRAFLEXI-1 study.
Diabetes Obes Metab. 2025; Doi: 10.1111/dom.70236
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Übersichtsarbeit

** Kirsch, A; Gindlhuber, J; Zabini, D; Osto, E Bile acids and incretins as modulators of obesity-associated atherosclerosis
FRONT CARDIOVASC MED. 2025; 11: 1510148 Doi: 10.3389/fcvm.2024.1510148 [OPEN ACCESS]
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** Liberale, L; Tual-Chalot, S; Sedej, S; Ministrini, S; Georgiopoulos, G; Grunewald, M; Bäck, M; Bochaton-Piallat, ML; Boon, RA; Ramos, GC; de, Winther, MPJ; Drosatos, K; Evans, PC; Ferguson, JF; Forslund-Startceva, SK; Goettsch, C; Giacca, M; Haendeler, J; Kallikourdis, M; Ketelhuth, DFJ; Koenen, RR; Lacolley, P; Lutgens, E; Maffia, P; Miwa, S; Monaco, C; Montecucco, F; Norata, GD; Osto, E; Richardson, GD; Riksen, NP; Soehnlein, O; Spyridopoulos, I; Van, Linthout, S; Vilahur, G; Wentzel, JJ; Andrés, V; Badimon, L; Benetos, A; Binder, CJ; Brandes, RP; Crea, F; Furman, D; Gorbunova, V; Guzik, TJ; Hill, JA; Lüscher, TF; Mittelbrunn, M; Nencioni, A; Netea, MG; Passos, JF; Stamatelopoulos, KS; Tavernarakis, N; Ungvari, Z; Wu, JC; Kirkland, JL; Camici, GG; Dimmeler, S; Kroemer, G; Abdellatif, M; Stellos, K Roadmap for alleviating the manifestations of ageing in the cardiovascular system.
Nat Rev Cardiol. 2025; 22(8):577-605 Doi: 10.1038/s41569-025-01130-5
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** Muralikrishnan, AS; Biasin, V; Zabini, D; Osto, E Immune and Vascular Function in Cardiometabolic Disorders: Interplay With Sex Differences and Impact on Incretin Therapy.
Acta Physiol (Oxf). 2025; 241(9):e70091 Doi: 10.1111/apha.70091 [OPEN ACCESS]
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Editorial

** Piani, F; Liberale, L; Osto, E Inflammaging and vascular ageing: untangling the threads of arterial stiffness and systemic inflammation
EUR J PREV CARDIOL. 2025; Doi: 10.1093/eurjpc/zwaf499
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2024

Originalarbeit (Zeitschrift)

** Burrello, J; Goi, J; Burrello, A; Vacchi, E; Rendon-Angel, A; Lazzarini, E; Bianco, G; Limongelli, V; Vassalli, G; Cereda, CW; Monticone, S; Mulatero, P; Bussolati, B; Alimonti, A; Camici, GG; Melli, G; Osto, E; Pedrazzini, G; Lucio, B Age- and sex-related variations in extracellular vesicle profiling for the assessment of cardiovascular risk: the EVaging index.
NPJ Aging. 2024; 10(1): 63 Doi: 10.1038/s41514-024-00189-7 [OPEN ACCESS]
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** Delko, T; Kraljević, M; Lazaridis, II; Köstler, T; Jomard, A; Taheri, A; Lutz, TA; Osto, E; Zingg, U Laparoscopic Roux-Y-gastric bypass versus laparoscopic one-anastomosis gastric bypass for obesity: clinical & metabolic results of a prospective randomized controlled trial.
Surg Endosc. 2024; Doi: 10.1007/s00464-024-10907-7
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** Pirri, D; Tian, S; Tardajos-Ayllon, B; Irving, S; Donati, F; Allen, SP; Mammoto, T; Vilahur, G; Kabir, L; Bennett, J; Rasool, Y; Pericleous, C; Mazzei, G; McAllan, L; Scott, WR; Koestler, T; Zingg, U; Birdsey, G; Miller, C; Schenkel, T; Chambers, EV; Dunning, M; Serbanovic-Canic, J; Botrè, F; Mammoto, A; Xu, S; Osto, E; Han, W; Fragiadaki, M; Evans, PC EPAS1 Attenuates Atherosclerosis Initiation at Disturbed Flow Sites Through Endothelial Fatty Acid Uptake.
Circ Res. 2024; Doi: 10.1161/CIRCRESAHA.123.324054 [OPEN ACCESS]
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** Simonenko, M; Hansen, D; Niebauer, J; Volterrani, M; Adamopoulos, S; Amarelli, C; Ambrosetti, M; Anker, SD; Bayes-Genis, A; Ben, Gal, T; Bowen, TS; Cacciatore, F; Caminiti, G; Cavarretta, E; Chioncel, O; Coats, AJS; Cohen-Solal, A; D'Ascenzi, F; de, Pablo, Zarzosa, C; Gevaert, AB; Gustafsson, F; Kemps, H; Hill, L; Jaarsma, T; Jankowska, E; Joyce, E; Krankel, N; Lainscak, M; Lund, LH; Moura, B; Nytrøen, K; Osto, E; Piepoli, M; Potena, L; Rakisheva, A; Rosano, G; Savarese, G; Seferovic, PM; Thompson, DR; Thum, T; Van, Craenenbroeck, EM Prevention and Rehabilitation After Heart Transplantation: A Clinical Consensus Statement of the European Association of Preventive Cardiology, Heart Failure Association of the ESC, and the European Cardio Thoracic Transplant Association, a Section of ESOT.
Transpl Int. 2024; 37: 13191 Doi: 10.3389/ti.2024.13191 [OPEN ACCESS]
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** Simonenko, M; Hansen, D; Niebauer, J; Volterrani, M; Adamopoulos, S; Amarelli, C; Ambrosetti, M; Anker, SD; Bayes-Genis, A; Gal, TB; Bowen, TS; Cacciatore, F; Caminiti, G; Cavaretta, E; Chioncel, O; Coats, AJS; Cohen-Solal, A; D'Ascenzi, F; de, Pablo, Zarzosa, C; Gevaert, AB; Gustafsson, F; Kemps, H; Hill, L; Jaarsma, T; Jankowska, E; Joyce, E; Krankel, N; Lainscak, M; Lund, LH; Moura, B; Nytrøen, K; Osto, E; Piepoli, M; Potena, L; Rakisheva, A; Rosano, G; Savarese, G; Seferovic, PM; Thompson, DR; Thum, T; Van, Craenenbroeck, EM Prevention and rehabilitation after heart transplantation: A clinical consensus statement of the European Association of Preventive Cardiology, Heart Failure Association of the ESC, and the European Cardio Thoracic Transplant Association, a section of ESOT.
Eur J Prev Cardiol. 2024; Doi: 10.1093/eurjpc/zwae179
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** Simonenko, M; Hansen, D; Niebauer, J; Volterrani, M; Adamopoulos, S; Amarelli, C; Ambrosetti, M; Anker, SD; Bayes-Genis, A; Gal, TB; Bowen, TS; Cacciatore, F; Caminiti, G; Cavaretta, E; Chioncel, O; Coats, AJS; Cohen-Solal, A; D'Ascenzi, F; Zarzosa, CD; Gevaert, AB; Gustafsson, F; Kemps, H; Hill, L; Jaarsma, T; Jankowska, E; Joyce, E; Krankel, N; Lainscak, M; Lund, LH; Moura, B; Nytroen, K; Osto, E; Piepoli, M; Potena, L; Rakisheva, A; Rosano, G; Savarese, G; Seferovic, PM; Thompson, DR; Thum, T; Van Craenenbroeck, EM Prevention and rehabilitation after heart transplantation: A clinical consensus statement of the European Association of Preventive Cardiology, Heart Failure Association of the ESC, and the European Cardio Thoracic Transplant Association, a section of ESOT
EUR J HEART FAIL. 2024; Doi: 10.1002/ejhf.3185
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Übersichtsarbeit

** Madreiter-Sokolowski, CT; Hiden, U; Krstic, J; Panzitt, K; Wagner, M; Enzinger, C; Khalil, M; Abdellatif, M; Malle, E; Madl, T; Osto, E; Schosserer, M; Binder, CJ; Olschewski, A Targeting organ-specific mitochondrial dysfunction to improve biological aging.
Pharmacol Ther. 2024; 262:108710 Doi: 10.1016/j.pharmthera.2024.108710
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Abstract (Zeitschrift)

** Osto, E Vascular function in cardiometabolic disorders.
ACTA PHYSIOL. 2024; 240: 7-7.-XXIII FEPS Meeting; SEP 4-6, 2024; Granada,SPAIN;. [Keynote lecture]
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Kommentar

** Kerkhof, PLM; Osto, E; Handly, N What characterizes device-related thrombosis following LAAC, if ejection fraction fails to shine?
ECHOCARDIOGR-J CARD. 2024; 41(8): e15902 Doi: 10.1111/echo.15902
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** Lutz, TA; Osto, E Deadly Sweet.
Eur J Prev Cardiol. 2024; Doi: 10.1093/eurjpc/zwae387
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2023

Originalarbeit (Zeitschrift)

** Civieri, G; Masiero, G; Osto, E; Gambino, A; Angelini, A; Fraiese, A; Fedrigo, M; Toscano, G; Bottio, T; Perazzolo, Marra, M; Iliceto, S; Gerosa, G; Tona, F Coronary Collateral Circulation: A New Predictor of Mortality in Heart Transplant Recipients With Allograft Vasculopathy.
Transplant Direct. 2023; 9(5): e1470 Doi: 10.1097/TXD.0000000000001470 [OPEN ACCESS]
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** Guo, J; Qiu, J; Jia, M; Li, Q; Wei, X; Li, L; Pan, Q; Jin, J; Ge, F; Ma, S; He, Y; Lin, J; Li, Y; Ma, J; Jiang, N; Zhi, X; Jiang, L; Zhang, J; Osto, E; Jing, Q; Wang, X; Meng, D BACH1 deficiency prevents neointima formation and maintains the differentiated phenotype of vascular smooth muscle cells by regulating chromatin accessibility.
Nucleic Acids Res. 2023; 51(9):4284-4301 Doi: 10.1093/nar/gkad120 [OPEN ACCESS]
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** He, Y; Guo, J; Yu, Y; Jin, J; Jiang, Q; Li, Q; Ma, S; Pan, Q; Lin, J; Jiang, N; Ma, J; Li, Y; Hou, Y; Zhi, X; Jiang, L; Qu, L; Osto, E; Wang, X; Wei, X; Meng, D BACH1 regulates the differentiation of vascular smooth muscle cells from human embryonic stem cells via CARM1-mediated methylation of H3R17.
Cell Rep. 2023; 42(12): 113468 Doi: 10.1016/j.celrep.2023.113468
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** Huwiler, S; Carro-Domínguez, M; Stich, FM; Sala, R; Aziri, F; Trippel, A; Ryf, T; Markendorf, S; Niederseer, D; Bohm, P; Stoll, G; Laubscher, L; Thevan, J; Spengler, CM; Gawinecka, J; Osto, E; Huber, R; Wenderoth, N; Schmied, C; Lustenberger, C Auditory stimulation of sleep slow waves enhances left ventricular function in humans.
Eur Heart J. 2023; 44(40): 4288-4291. Doi: 10.1093/eurheartj/ehad630 [OPEN ACCESS]
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** Jin, J; He, Y; Guo, J; Pan, Q; Wei, X; Xu, C; Qi, Z; Li, Q; Ma, S; Lin, J; Jiang, N; Ma, J; Wang, X; Jiang, L; Ding, Q; Osto, E; Zhi, X; Meng, D BACH1 controls hepatic insulin signaling and glucose homeostasis in mice.
Nat Commun. 2023; 14(1): 8428 Doi: 10.1038/s41467-023-44088-z [OPEN ACCESS]
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** Osto, E; Bonacina, F; Pirillo, A; Norata, GD Neutral effect of SGLT2 inhibitors on lipoprotein metabolism: From clinical evidence to molecular mechanisms.
Pharmacol Res. 2023; 188: 106667 Doi: 10.1016/j.phrs.2023.106667
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** Pedretti, RFE; Hansen, D; Ambrosetti, M; Back, M; Berger, T; Ferreira, MC; Cornelissen, V; Davos, CH; Doehner, W; de, Pablo, Y, Zarzosa, C; Frederix, I; Greco, A; Kurpas, D; Michal, M; Osto, E; Pedersen, SS; Salvador, RE; Simonenko, M; Steca, P; Thompson, DR; Wilhelm, M; Abreu, A How to optimize the adherence to a guideline-directed medical therapy in the secondary prevention of cardiovascular diseases: a clinical consensus statement from the European Association of Preventive Cardiology.
Eur J Prev Cardiol. 2023; 30(2): 149-166. Doi: 10.1093/eurjpc/zwac204
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** Stellato, M; Dewenter, M; Rudnik, M; Hukara, A; Özsoy, Ç; Renoux, F; Pachera, E; Gantenbein, F; Seebeck, P; Uhtjaerv, S; Osto, E; Razansky, D; Klingel, K; Henes, J; Distler, O; Błyszczuk, P; Kania, G The AP-1 transcription factor Fosl-2 drives cardiac fibrosis and arrhythmias under immunofibrotic conditions.
Commun Biol. 2023; 6(1): 161 Doi: 10.1038/s42003-023-04534-6 [OPEN ACCESS]
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** Wei, X; Jin, J; Wu, J; He, Y; Guo, J; Yang, Z; Chen, L; Hu, K; Li, L; Jia, M; Li, Q; Lv, X; Ge, F; Ma, S; Wu, H; Zhi, X; Wang, X; Jiang, L; Osto, E; Zhang, J; Meng, D Cardiac-specific BACH1 ablation attenuates pathological cardiac hypertrophy by inhibiting the Ang II type 1 receptor expression and the Ca2+/CaMKII pathway.
Cardiovasc Res. 2023; 119(9): 1842-1855. Doi: 10.1093/cvr/cvad086
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Übersichtsarbeit

** de, Winther, MPJ; Bäck, M; Evans, P; Gomez, D; Goncalves, I; Jørgensen, HF; Koenen, RR; Lutgens, E; Norata, GD; Osto, E; Dib, L; Simons, M; Stellos, K; Ylä-Herttuala, S; Winkels, H; Bochaton-Piallat, ML; Monaco, C Translational opportunities of single-cell biology in atherosclerosis.
Eur Heart J. 2023; 44(14): 1216-1230. Doi: 10.1093/eurheartj/ehac686 [OPEN ACCESS]
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Editorial

** Osto, E; Roeters, van, Lennep, JE; Tokgözoğlu, L; Öörni, K Influence of sex and gender on the biology of atherosclerotic cardiovascular disease: Special issue.
Atherosclerosis. 2023; 384: 117297 Doi: 10.1016/j.atherosclerosis.2023.117297
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Korrektur

** Stellato, M; Dewenter, M; Rudnik, M; Hukara, A; Özsoy, Ç; Renoux, F; Pachera, E; Gantenbein, F; Seebeck, P; Uhtjaerv, S; Osto, E; Razansky, D; Klingel, K; Henes, J; Distler, O; Błyszczuk, P; Kania, G Author Correction: The AP-1 transcription factor Fosl-2 drives cardiac fibrosis and arrhythmias under immunofibrotic conditions.
Commun Biol. 2023; 6(1): 213 Doi: 10.1038/s42003-023-04600-z [OPEN ACCESS]
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News-Item

** Lutgens, E; Osto, E; Bochaton-Piallat, ML The European Society of Cardiology working group on atherosclerosis and vascular biology.
Eur Heart J. 2023; Doi: 10.1093/eurheartj/ehad536
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2022

Originalarbeit (Zeitschrift)

** Cecere, A; Kerkhof, PLM; Civieri, G; Angelini, A; Gambino, A; Fraiese, A; Bottio, T; Osto, E; Famoso, G; Fedrigo, M; Giacomin, E; Toscano, G; Montisci, R; Iliceto, S; Gerosa, G; Tona, F Coronary Flow Evaluation in Heart Transplant Patients Compared to Healthy Controls Documents the Superiority of Coronary Flow Velocity Reserve Companion as Diagnostic and Prognostic Tool.
Front Cardiovasc Med. 2022; 9: 887370 Doi: 10.3389/fcvm.2022.887370 [OPEN ACCESS]
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** Jia, M; Li, Q; Guo, J; Shi, W; Zhu, L; Huang, Y; Li, Y; Wang, L; Ma, S; Zhuang, T; Wang, X; Pan, Q; Wei, X; Qin, Y; Li, X; Jin, J; Zhi, X; Tang, J; Jing, Q; Li, S; Jiang, L; Qu, L; Osto, E; Zhang, J; Wang, X; Yu, B; Meng, D Deletion of BACH1 Attenuates Atherosclerosis by Reducing Endothelial Inflammation.
Circ Res. 2022; 130(7): 1038-1055. Doi: 10.1161/CIRCRESAHA.121.319540
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** Jomard, A; Liberale, L; Doytcheva, P; Reiner, MF; Müller, D; Visentin, M; Bueter, M; Lüscher, TF; Vettor, R; Lutz, TA; Camici, GG; Osto, E Effects of acute administration of trimethylamine N-oxide on endothelial function: a translational study.
Sci Rep. 2022; 12(1): 8664 Doi: 10.1038/s41598-022-12720-5 [OPEN ACCESS]
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** Koskinas, KC; Dendale, P; Halle, M; Caselli, S; Cornelissen, V; Kavousi, M; Kurpas, D; Osto, E; Raupach, T; Semb, AG; Pedretti, RFE Introducing the new Task Force on Cardiovascular Risk Factors of the European Association of Preventive Cardiology.
Eur J Prev Cardiol. 2022; 29(13): 1718-1720. Doi: 10.1093/eurjpc/zwac118
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** Sudano, I; Osto, E; Ruschitzka, F Blood Pressure-Lowering Therapy.
Handb Exp Pharmacol. 2022; 270: 25-45. Doi: 10.1007/164_2020_372
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** Tona, F; Osto, E; Kerkhof, PLM; Montisci, R; Famoso, G; Lorenzoni, G; De, Michieli, L; Cecere, A; Zanetti, I; Civieri, G; Iliceto, S; Piaserico, S Multiparametric analysis of coronary flow in psoriasis using a coronary flow reserve companion.
Eur J Clin Invest. 2022; 52(4): e13711 Doi: 10.1111/eci.13711 [OPEN ACCESS]
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Übersichtsarbeit

** Dietrich, E; Jomard, A; Osto, E Crosstalk between high-density lipoproteins and endothelial cells in health and disease: Insights into sex-dependent modulation.
Front Cardiovasc Med. 2022; 9: 989428 Doi: 10.3389/fcvm.2022.989428 [OPEN ACCESS]
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** Evans, PC; Davidson, SM; Wojta, J; Bäck, M; Bollini, S; Brittan, M; Catapano, AL; Chaudhry, B; Cluitmans, M; Gnecchi, M; Guzik, TJ; Hoefer, I; Madonna, R; Monteiro, JP; Morawietz, H; Osto, E; Padró, T; Sluimer, JC; Tocchetti, CG; Van, der, Heiden, K; Vilahur, G; Waltenberger, J; Weber, C From novel discovery tools and biomarkers to precision medicine-basic cardiovascular science highlights of 2021/22.
Cardiovasc Res. 2022; 118(13): 2754-2767. Doi: 10.1093/cvr/cvac114 [OPEN ACCESS]
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** Gevaert, AB; Wood, N; Boen, JRA; Davos, CH; Hansen, D; Hanssen, H; Krenning, G; Moholdt, T; Osto, E; Paneni, F; Pedretti, RFE; Plösch, T; Simonenko, M; Bowen, TS Epigenetics in the primary and secondary prevention of cardiovascular disease: influence of exercise and nutrition.
Eur J Prev Cardiol. 2022; 29(17): 2183-2199. Doi: 10.1093/eurjpc/zwac179
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Korrektur

** Sudano, I; Osto, E; Ruschitzka, F Correction to: Blood Pressure-Lowering Therapy.
Handb Exp Pharmacol. 2022; 270: 537-538. Doi: 10.1007/164_2020_410
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Kommentar

** Osto, E The promise of the gut metabolite propionate for a novel and personalized lipid-lowering treatment.
Eur Heart J. 2022; 43(6): 534-537. Doi: 10.1093/eurheartj/ehab723 [OPEN ACCESS]
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2021

Originalarbeit (Zeitschrift)

** Bengs, S; Haider, A; Warnock, GI; Fiechter, M; Pargaetzi, Y; Rampidis, G; Etter, D; Wijnen, WJ; Portmann, A; Osto, E; Treyer, V; Benz, DC; Meisel, A; Fuchs, TA; Gräni, C; Buechel, RR; Kaufmann, PA; Pazhenkottil, AP; Gebhard, C Quantification of perivascular inflammation does not provide incremental prognostic value over myocardial perfusion imaging and calcium scoring.
Eur J Nucl Med Mol Imaging. 2021; 48(6):1806-1812 Doi: 10.1007/s00259-020-05106-0 [OPEN ACCESS]
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** Bonetti, NR; Liberale, L; Akhmedov, A; Pasterk, L; Gobbato, S; Puspitasari, YM; Vukolic, A; Saeedi, Saravi, SS; Coester, B; Horvath, C; Osto, E; Montecucco, F; Lüscher, TF; Beer, JH; Camici, GG Long-term dietary supplementation with plant-derived omega-3 fatty acid improves outcome in experimental ischemic stroke.
Atherosclerosis. 2021; 325:89-98 Doi: 10.1016/j.atherosclerosis.2021.04.005
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** Ge, F; Pan, Q; Qin, Y; Jia, M; Ruan, C; Wei, X; Jing, Q; Zhi, X; Wang, X; Jiang, L; Osto, E; Guo, J; Meng, D Single-Cell Analysis Identify Transcription Factor BACH1 as a Master Regulator Gene in Vascular Cells During Aging.
Front Cell Dev Biol. 2021; 9: 786496 Doi: 10.3389/fcell.2021.786496 [OPEN ACCESS]
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Übersichtsarbeit

** Alexander, Y; Osto, E; Schmidt-Trucksäss, A; Shechter, M; Trifunovic, D; Duncker, DJ; Aboyans, V; Bäck, M; Badimon, L; Cosentino, F; De, Carlo, M; Dorobantu, M; Harrison, DG; Guzik, TJ; Hoefer, I; Morris, PD; Norata, GD; Suades, R; Taddei, S; Vilahur, G; Waltenberger, J; Weber, C; Wilkinson, F; Bochaton-Piallat, ML; Evans, PC Endothelial function in cardiovascular medicine: a consensus paper of the European Society of Cardiology Working Groups on Atherosclerosis and Vascular Biology, Aorta and Peripheral Vascular Diseases, Coronary Pathophysiology and Microcirculation, and Thrombosis.
Cardiovasc Res. 2021; 117(1):29-42 Doi: 10.1093/cvr/cvaa085 [OPEN ACCESS]
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** Robert, J; Osto, E; von, Eckardstein, A The Endothelium Is Both a Target and a Barrier of HDL's Protective Functions.
Cells. 2021; 10(5): Doi: 10.3390/cells10051041 [OPEN ACCESS]
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2020

Originalarbeit (Zeitschrift)

** Oppi, S; Nusser-Stein, S; Blyszczuk, P; Wang, X; Jomard, A; Marzolla, V; Yang, K; Velagapudi, S; Ward, LJ; Yuan, XM; Geiger, MA; Guillaumon, AT; Othman, A; Hornemann, T; Rancic, Z; Ryu, D; Oosterveer, MH; Osto, E; Lüscher, TF; Stein, S Macrophage NCOR1 protects from atherosclerosis by repressing a pro-atherogenic PPARγ signature.
Eur Heart J. 2020; 41(9):995-1005 Doi: 10.1093/eurheartj/ehz667
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** Osto, E A portrait of the ESC Working Group Atherosclerosis and Vascular Biology.
Eur Heart J. 2020; 41(24):2233-2235 Doi: 10.1093/eurheartj/ehaa304
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Übersichtsarbeit

** Evans, PC; Rainger, GE; Mason, JC; Guzik, TJ; Osto, E; Stamataki, Z; Neil, D; Hoefer, IE; Fragiadaki, M; Waltenberger, J; Weber, C; Bochaton-Piallat, ML; Bäck, M Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic Cardiovascular Science.
Cardiovasc Res. 2020; 116(14):2177-2184 Doi: 10.1093/cvr/cvaa230 [OPEN ACCESS]
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** Haider, A; Bengs, S; Luu, J; Osto, E; Siller-Matula, JM; Muka, T; Gebhard, C Sex and gender in cardiovascular medicine: presentation and outcomes of acute coronary syndrome.
Eur Heart J. 2020; 41(13):1328-1336 Doi: 10.1093/eurheartj/ehz898
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** Jomard, A; Osto, E High Density Lipoproteins: Metabolism, Function, and Therapeutic Potential.
Front Cardiovasc Med. 2020; 7:39 Doi: 10.3389/fcvm.2020.00039 [OPEN ACCESS]
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Abstract (Konferenzband)

** Jomard, A; Chavez-Talavera, O; Doytcheva, P; Tailleux, A; Wolfrum, C; Lutz, T; Ruschitzka, F; von, Eckardstein, A; Staels, B; Osto, E Best Poster Award - Second Prize: Bile Acids as Novel Vascular Signalling Molecules and Therapeutic Target.
Eur Cardiol. European Cardiology Review 2020. 2020; 15: e25--24th Annual Scientific Meeting of the International Society of Cardiovascular Pharmacotherapy; MAY 9-10, 2019; Lugano, Switzerland. Doi: 10.15420/ecr.2020.15.1.PO2 [Poster] [OPEN ACCESS]
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2019

Originalarbeit (Zeitschrift)

** Haider, A; Possner, M; Messerli, M; Bengs, S; Osto, E; Maredziak, M; Portmann, A; Fiechter, M; Giannopoulos, AA; Treyer, V; Gaisl, T; von, Felten, E; Patriki, D; Benz, DC; Fuchs, TA; Gräni, C; Pazhenkottil, AP; Buechel, RR; Kaufmann, PA; Gebhard, C Quantification of intrathoracic fat adds prognostic value in women undergoing myocardial perfusion imaging.
Int J Cardiol. 2019; 292:258-264 Doi: 10.1016/j.ijcard.2019.04.092
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** Kerkhof, PLM; Osto, E; Tona, F; Heyndrickx, GR; Handly, N Sex-Specific Interpretation of Coronary Flow Reserve and Fractional Flow Reserve Metrics, Including Their Companions.
Annu Int Conf IEEE Eng Med Biol Soc. 2019; 2019: 7006-7009. Doi: 10.1109/EMBC.2019.8857589
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** Piaserico, S; Osto, E; Famoso, G; Montisci, R; De, Michieli, L; Zanetti, I; Iliceto, S; Tona, F Long-term prognostic value of coronary flow reserve in psoriasis patients.
Atherosclerosis. 2019; 289:57-63 Doi: 10.1016/j.atherosclerosis.2019.08.009
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Übersichtsarbeit

** Dal, Lin, C; Tona, F; Osto, E The crosstalk between the cardiovascular and the immune system.
Vasc Biol. 2019; 1(1): H83-H88. Doi: 10.1530/VB-19-0023 [OPEN ACCESS]
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** Jomard, A; Osto, E [Metabolism and Function of High-Density Lipoproteins (HDL)].
Praxis (Bern 1994). 2019; 108(7): 477-486. Doi: 10.1024/1661-8157/a003241
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2018

Originalarbeit (Zeitschrift)

** Kerkhof, PLM; Osto, E Women and Men in the History of Western Cardiology: Some Notes on Their Position as Patients, Role as Investigational Study Subjects, and Impact as Professionals.
Adv Exp Med Biol. 2018; 1065:1-30 Doi: 10.1007/978-3-319-77932-4_1
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** Tellatin, S; Maffei, P; Osto, E; Dassie, F; Famoso, G; Montisci, R; Martini, C; Fallo, F; Marra, MP; Mioni, R; Iliceto, S; Vettor, R; Tona, F Coronary microvascular dysfunction may be related to IGF-1 in acromegalic patients and can be restored by therapy.
Atherosclerosis. 2018; 269:100-105 Doi: 10.1016/j.atherosclerosis.2017.12.019
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Übersichtsarbeit

** Dal, Lin, C; Tona, F; Osto, E The Heart as a Psychoneuroendocrine and Immunoregulatory Organ.
Adv Exp Med Biol. 2018; 1065:225-239 Doi: 10.1007/978-3-319-77932-4_15
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** Previato, M; Osto, E; Kerkhof, PLM; Parry, G; Tona, F Heart Transplantation Survival and Sex-Related Differences.
Adv Exp Med Biol. 2018; 1065:379-388 Doi: 10.1007/978-3-319-77932-4_24
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2017

Originalarbeit (Zeitschrift)

** Blyszczuk, P; Müller-Edenborn, B; Valenta, T; Osto, E; Stellato, M; Behnke, S; Glatz, K; Basler, K; Lüscher, TF; Distler, O; Eriksson, U; Kania, G Transforming growth factor-β-dependent Wnt secretion controls myofibroblast formation and myocardial fibrosis progression in experimental autoimmune myocarditis.
Eur Heart J. 2017; 38(18):1413-1425 Doi: 10.1093/eurheartj/ehw116
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** Doytcheva, P; Bächler, T; Tarasco, E; Marzolla, V; Engeli, M; Pellegrini, G; Stivala, S; Rohrer, L; Tona, F; Camici, GG; Vanhoutte, PM; Matter, CM; Lutz, TA; Lüscher, TF; Osto, E Inhibition of Vascular c-Jun N-Terminal Kinase 2 Improves Obesity-Induced Endothelial Dysfunction After Roux-en-Y Gastric Bypass.
J Am Heart Assoc. 2017; 6(11): Doi: 10.1161/JAHA.117.006441 [OPEN ACCESS]
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** Kraljević, M; Delko, T; Köstler, T; Osto, E; Lutz, T; Thommen, S; Droeser, RA; Rothwell, L; Oertli, D; Zingg, U Laparoscopic Roux-en-Y gastric bypass versus laparoscopic mini gastric bypass in the treatment of obesity: study protocol for a randomized controlled trial.
Trials. 2017; 18(1):226 Doi: 10.1186/s13063-017-1957-9 [OPEN ACCESS]
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** Simic, B; Mocharla, P; Crucet, M; Osto, E; Kratzer, A; Stivala, S; Kühnast, S; Speer, T; Doycheva, P; Princen, HM; van, der, Hoorn, JW; Jukema, JW; Giral, H; Tailleux, A; Landmesser, U; Staels, B; Lüscher, TF Anacetrapib, but not evacetrapib, impairs endothelial function in CETP-transgenic mice in spite of marked HDL-C increase.
Atherosclerosis. 2017; 257:186-194 Doi: 10.1016/j.atherosclerosis.2017.01.011
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2016

Originalarbeit (Zeitschrift)

** Müller-Edenborn, B; Kania, G; Osto, E; Jakob, P; Krasniqi, N; Beck-Schimmer, B; Blyszczuk, P; Eriksson, U Lidocaine Enhances Contractile Function of Ischemic Myocardial Regions in Mouse Model of Sustained Myocardial Ischemia.
PLoS One. 2016; 11(5):e0154699 Doi: 10.1371/journal.pone.0154699 [OPEN ACCESS]
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** Piaserico, S; Osto, E; Famoso, G; Zanetti, I; Gregori, D; Poretto, A; Iliceto, S; Peserico, A; Tona, F Treatment with tumor necrosis factor inhibitors restores coronary microvascular function in young patients with severe psoriasis.
Atherosclerosis. 2016; 251:25-30 Doi: 10.1016/j.atherosclerosis.2016.05.036
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** Spinelli, V; Lalloyer, F; Baud, G; Osto, E; Kouach, M; Daoudi, M; Vallez, E; Raverdy, V; Goossens, JF; Descat, A; Doytcheva, P; Hubert, T; Lutz, TA; Lestavel, S; Staels, B; Pattou, F; Tailleux, A Influence of Roux-en-Y gastric bypass on plasma bile acid profiles: a comparative study between rats, pigs and humans.
Int J Obes (Lond). 2016; 40(8):1260-7 Doi: 10.1038/ijo.2016.46
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Übersichtsarbeit

** Lutz, TA; Osto, E Glucagon-like peptide-1, glucagon-like peptide-2, and lipid metabolism.
Curr Opin Lipidol. 2016; 27(3):257-63 Doi: 10.1097/MOL.0000000000000293
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2015

Originalarbeit (Zeitschrift)

** Osto, E; Doytcheva, P; Corteville, C; Bueter, M; Dörig, C; Stivala, S; Buhmann, H; Colin, S; Rohrer, L; Hasballa, R; Tailleux, A; Wolfrum, C; Tona, F; Manz, J; Vetter, D; Spliethoff, K; Vanhoutte, PM; Landmesser, U; Pattou, F; Staels, B; Matter, CM; Lutz, TA; Lüscher, TF Rapid and body weight-independent improvement of endothelial and high-density lipoprotein function after Roux-en-Y gastric bypass: role of glucagon-like peptide-1.
Circulation. 2015; 131(10):871-81 Doi: 10.1161/CIRCULATIONAHA.114.011791
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** Tona, F; Osto, E; Famoso, G; Previato, M; Fedrigo, M; Vecchiati, A; Perazzolo, Marra, M; Tellatin, S; Bellu, R; Tarantini, G; Feltrin, G; Angelini, A; Thiene, G; Gerosa, G; Iliceto, S Coronary microvascular dysfunction correlates with the new onset of cardiac allograft vasculopathy in heart transplant patients with normal coronary angiography.
Am J Transplant. 2015; 15(5):1400-6 Doi: 10.1111/ajt.13108
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** Vianello, F; Cella, G; Osto, E; Ballin, A; Famoso, G; Tellatin, S; Iliceto, S; Cucchini, U; Saggiorato, G; Omenetto, E; Tona, F Coronary microvascular dysfunction due to essential thrombocythemia and policythemia vera: the missing piece in the puzzle of their increased cardiovascular risk?
Am J Hematol. 2015; 90(2):109-13 Doi: 10.1002/ajh.23881
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Übersichtsarbeit

** Dal, Lin, C; Tona, F; Osto, E Coronary Microvascular Function and Beyond: The Crosstalk between Hormones, Cytokines, and Neurotransmitters.
Int J Endocrinol. 2015; 2015:312848 Doi: 10.1155/2015/312848 [OPEN ACCESS]
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2014

Originalarbeit (Zeitschrift)

** Tona, F; Serra, R; Di, Ascenzo, L; Osto, E; Scarda, A; Fabris, R; Montisci, R; Famoso, G; Tellatin, S; Foletto, M; Giovagnoni, A; Iliceto, S; Vettor, R Systemic inflammation is related to coronary microvascular dysfunction in obese patients without obstructive coronary disease.
Nutr Metab Cardiovasc Dis. 2014; 24(4):447-53 Doi: 10.1016/j.numecd.2013.09.021
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2013

Originalarbeit (Zeitschrift)

** Paneni, F; Osto, E; Costantino, S; Mateescu, B; Briand, S; Coppolino, G; Perna, E; Mocharla, P; Akhmedov, A; Kubant, R; Rohrer, L; Malinski, T; Camici, GG; Matter, CM; Mechta-Grigoriou, F; Volpe, M; Lüscher, TF; Cosentino, F Deletion of the activated protein-1 transcription factor JunD induces oxidative stress and accelerates age-related endothelial dysfunction.
Circulation. 2013; 127(11):1229-40, e1-21 Doi: 10.1161/CIRCULATIONAHA.112.000826
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2012

Originalarbeit (Zeitschrift)

** Osto, E; Fallo, F; Pelizzo, MR; Maddalozzo, A; Sorgato, N; Corbetti, F; Montisci, R; Famoso, G; Bellu, R; Lüscher, TF; Iliceto, S; Tona, F Coronary microvascular dysfunction induced by primary hyperparathyroidism is restored after parathyroidectomy.
Circulation. 2012; 126(9):1031-9 Doi: 10.1161/CIRCULATIONAHA.111.081307
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** Osto, E; Piaserico, S; Maddalozzo, A; Forchetti, G; Montisci, R; Famoso, G; Giovagnoni, A; Peserico, A; Iliceto, S; Tona, F Impaired coronary flow reserve in young patients affected by severe psoriasis.
Atherosclerosis. 2012; 221(1):113-7 Doi: 10.1016/j.atherosclerosis.2011.12.015
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** Paneni, F; Mocharla, P; Akhmedov, A; Costantino, S; Osto, E; Volpe, M; Lüscher, TF; Cosentino, F Gene silencing of the mitochondrial adaptor p66(Shc) suppresses vascular hyperglycemic memory in diabetes.
Circ Res. 2012; 111(3):278-89 Doi: 10.1161/CIRCRESAHA.112.266593
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2011

Originalarbeit (Zeitschrift)

** Osto, E; Castellani, C; Fadini, GP; Baesso, I; Gambino, A; Agostini, C; Avogaro, A; Gerosa, G; Thiene, G; Iliceto, S; Angelini, A; Tona, F Impaired endothelial progenitor cell recruitment may contribute to heart transplant microvasculopathy.
J Heart Lung Transplant. 2011; 30(1):70-6 Doi: 10.1016/j.healun.2010.07.004
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2010

Originalarbeit (Zeitschrift)

** Tarantini, G; Napodano, M; Gasparetto, N; Favaretto, E; Marra, MP; Cacciavillani, L; Bilato, C; Osto, E; Cademartiri, F; Musumeci, G; Corbetti, F; Razzolini, R; Iliceto, S Impact of multivessel coronary artery disease on early ischemic injury, late clinical outcome, and remodeling in patients with acute myocardial infarction treated by primary coronary angioplasty.
Coron Artery Dis. 2010; 21(2):78-86 Doi: 10.1097/MCA.0b013e328335a074
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** Tona, F; Osto, E; Tarantini, G; Gambino, A; Cavallin, F; Feltrin, G; Montisci, R; Caforio, AL; Gerosa, G; Iliceto, S Coronary flow reserve by transthoracic echocardiography predicts epicardial intimal thickening in cardiac allograft vasculopathy.
Am J Transplant. 2010; 10(7):1668-76 Doi: 10.1111/j.1600-6143.2010.03160.x
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Übersichtsarbeit

** Osto, E; Tona, F; De, Bon, E; Iliceto, S; Cella, G Endothelial dysfunction in cardiac allograft vasculopathy: potential pharmacological interventions.
Curr Vasc Pharmacol. 2010; 8(2):169-88 Doi: 10.2174/157016110790886992
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2009

Originalarbeit (Zeitschrift)

** Osto, E; Tona, F; Angelini, A; Montisci, R; Ruscazio, M; Vinci, A; Tarantini, G; Ramondo, A; Gambino, A; Thiene, G; Caforio, AL; Gerosa, G; Iliceto, S Determinants of coronary flow reserve in heart transplantation: a study performed with contrast-enhanced echocardiography.
J Heart Lung Transplant. 2009; 28(5):453-60 Doi: 10.1016/j.healun.2009.02.008
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2008

Originalarbeit (Zeitschrift)

** Delli, Gatti, C; Osto, E; Kouroedov, A; Eto, M; Shaw, S; Volpe, M; Lüscher, TF; Cosentino, F Pulsatile stretch induces release of angiotensin II and oxidative stress in human endothelial cells: effects of ACE inhibition and AT1 receptor antagonism.
Clin Exp Hypertens. 2008; 30(7):616-27 Doi: 10.1080/10641960802443183
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** Osto, E; Kouroedov, A; Mocharla, P; Akhmedov, A; Besler, C; Rohrer, L; von, Eckardstein, A; Iliceto, S; Volpe, M; Lüscher, TF; Cosentino, F Inhibition of protein kinase Cbeta prevents foam cell formation by reducing scavenger receptor A expression in human macrophages.
Circulation. 2008; 118(21):2174-82 Doi: 10.1161/CIRCULATIONAHA.108.789537
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** Osto, E; Matter, CM; Kouroedov, A; Malinski, T; Bachschmid, M; Camici, GG; Kilic, U; Stallmach, T; Boren, J; Iliceto, S; Lüscher, TF; Cosentino, F c-Jun N-terminal kinase 2 deficiency protects against hypercholesterolemia-induced endothelial dysfunction and oxidative stress.
Circulation. 2008; 118(20):2073-80 Doi: 10.1161/CIRCULATIONAHA.108.765032
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2007

Übersichtsarbeit

** Cosentino, F; Osto, E Aging and endothelial dysfunction.
Clin Hemorheol Microcirc. 2007; 37(1-2):143-7
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** Osto, E; Coppolino, G; Volpe, M; Cosentino, F Restoring the dysfunctional endothelium.
Curr Pharm Des. 2007; 13(10):1053-68 Doi: 10.2174/138161207780487566
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