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** = Publications listed in SCI/SSCI/Pubmed

2025

Full paper/article (Journal)

** Pedersen, ESL; Glick, S; Jong, CCMD; Ardura-Garcia, C; Jochmann, A; Casaulta, C; Hartog, K; Marangu-Boore, D; Mueller-Suter, D; Regamey, N; Singer, F; Moeller, A; Kuehni, CE Reporting of paediatric exercise-induced respiratory symptoms by physicians and parents: an observational prospective study
SWISS MED WKLY. 2025; 155(4): 3939 Doi: 10.57187/s.3939
Web of Science FullText FullText_MUG

 

Abstract (Journal)

** Schaffer, A; Mozun, R; Kentgens, AC; Zimmermann, T; Mallet, MC; Kuehni, CE; Latzin, P; Usemann, J; Möller, A; Herzog, S; Singer, F Latent classes in unselected schoolchildren: respiratory symptoms and treatment burden. The LuftiBus in the school (LUIS) study
KLIN PADIATR. 2025; 237(02): S2-S2. Doi: 10.1055/s-0045-1802480
Web of Science FullText FullText_MUG

 

2024

Full paper/article (Journal)

** Kasteler, R; Otth, M; Halbeisen, FS; Mader, L; Singer, F; Rössler, J; von, der, Weid, NX; Ansari, M; Kuehni, CE Longitudinal assessment of lung function in Swiss childhood cancer survivors-A multicenter cohort study.
Pediatr Pulmonol. 2024; 59(1):169-180 Doi: 10.1002/ppul.26738
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** Kentgens, AC; Kurz, JM; Mozun, R; Usemann, J; Pedersen, ESL; Kuehni, CE; Latzin, P; Moeller, A; Singer, F, , LuftiBus, In, the, School, (LUIS), Study, Group Evaluation of the Double-Tracer Gas Single-Breath Washout Test in a Pediatric Field Study.
Chest. 2024; 165(2):396-404 Doi: 10.1016/j.chest.2023.09.006 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Khaleva, E; Brightling, C; Eiwegger, T; Altraja, A; Bégin, P; Blumchen, K; Bossios, A; Bourdin, A; Ten, Brinke, A; Brusselle, G; Silvia, Bumbacea, R; Bush, A; Casale, TB; Clarke, GW; Chaudhuri, R; Fan, Chung, K; Coleman, C; Corren, J; Dahlén, SE; Deschildre, A; Djukanovic, R; Eger, K; Exley, A; Fleming, L; Fowler, SJ; Gaillard, EA; Gappa, M; Gupta, A; Michael, Haitchi, H; Hashimoto, S; Heaney, LG; Hedlin, G; Henderson, M; Hua, W; Jackson, DJ; Karadag, B; Helen, Katelaris, C; Koh, MS; Volkmar, Kopp, M; Koppelman, GH; Kull, I; Kurukulaaratchy, RJ; Lee, JH; Mahler, V; Mäkelä, M; Masoli, M; Mathioudakis, AG; Mazon, A; Melén, E; Milger, K; Moeller, A; Murray, CS; Nagakumar, P; Nair, P; Negus, J; Nieto, A; Papadopoulos, NG; Paton, J; Pijnenburg, MW; Pike, KC; Porsbjerg, C; Rattu, A; Rupani, H; Rusconi, F; Rutjes, NW; Saglani, S; Seddon, P; Siddiqui, S; Singer, F; Tajiri, T; Turner, S; Upham, JW; Vijverberg, SJH; Wark, PAB; Wechsler, ME; Yasinska, V; Roberts, G Patient-centred composite scores as tools for assesment of response to biological therapy for paediatric and adult severe asthma.
Eur Respir J. 2024; Doi: 10.1183/13993003.00691-2024 [OPEN ACCESS]
PubMed PUBMED Central FullText FullText_MUG

 

** Meys, R; Franssen, FME; Van, 't, Hul, AJ; Bakke, PS; Caruso, M; Dahlén, B; Fowler, SJ; Geiser, T; Howarth, PH; Horváth, I; Krug, N; Behndig, AF; Singer, F; Musial, J; Shaw, DE; Montuschi, P; Zee, AHM; Sterk, PJ; Roberts, G; Kermani, NZ; Incalzi, RA; Louis, R; Andersson, LI; Wagers, SS; Dahlén, SE; Chung, KF; Adcock, IM; Spruit, MA, , U-BIOPRED, Study, Group Clinical importance of patient-reported outcome measures in severe asthma: results from U-BIOPRED.
Health Qual Life Outcomes. 2024; 22(1): 109 Doi: 10.1186/s12955-024-02321-3 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Shahbazi, Khamas, S; Van, Dijk, Y; Abdel-Aziz, MI; Neerincx, AH; Maarten, Blankestijn, J; Vijverberg, SJH; Hashimoto, S; Bush, A; Kraneveld, AD; Hedman, AM; Toncheva, AA; Almqvist, C; Wolff, C; Murray, CS; Hedlin, G; Roberts, G; Adcock, IM; Korta-Murua, J; Bønnelykke, K; Fleming, LJ; Pino-Yanes, M; Gorenjak, M; Kabesch, M; Sardón-Prado, O; Montuschi, P; Singer, F; Elosegui, PC; Fowler, SJ; Brandstetter, S; Harner, S; Dahlén, SE; Potočnik, U; Frey, U; van, Aalderen, W; Brinkman, P; Maitland-van, der, Zee, AH, , SysPharmPediA, and, U-BIOPRED, Consortia Exhaled Volatile Organic Compounds for Asthma Control Classification in Children with Moderate to Severe Asthma: Results from the SysPharmPediA Study.
Am J Respir Crit Care Med. 2024; 210(9):1091-1100 Doi: 10.1164/rccm.202312-2270OC
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** Usemann, J; Mozun, R; Kuehni, CE; de, Hoogh, K; Flueckiger, B; Singer, F; Zwahlen, M; Moeller, A; Latzin, P, , LUIS, Study, Group Air pollution exposure during pregnancy and lung function in childhood: The LUIS study.
Pediatr Pulmonol. 2024; 59(12):3178-3189 Doi: 10.1002/ppul.27169 [OPEN ACCESS]
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Abstract (Journal)

** Carlens, J; Nyilas, S; Voskrebenzev, A; Schwerk, N; Singer, F; Ius, F; Renz, D; Vogel-Claussen, J Phase resolved functional lung (PREFUL) MRI detects ventilation and perfusion deficits in paediatric lung transplant recipients
EUR RESPIR J. 2024; 64: OA4688 Doi: 10.1183/13993003.congress-2024.OA4688 [Oral Communication]
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** Raffler, G; Schneider, C; Singer, F; Wyler, F; Moeller, A; Guengoer, T; Hauri, M; Usemann, J Pulmonary function in children after hematopoietic stem cell transplantation: a retrospective analysis
EUR RESPIR J. 2024; 64: OA2898 Doi: 10.1183/13993003.congress-2024.OA2898 [Oral Communication]
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** Schaffer, AM; Herzog, S; Latzin, P; Singer, F Clusters of lung clearance index trajectories and survival in people with cystic fibrosis
EUR RESPIR J. 2024; 64: PA562 Doi: 10.1183/13993003.congress-2024.PA562 [Poster]
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** Schaffer, AM; Latzin, P; Herzog, SA; Singer, F Lung clearance index trajectories and survival in people with cystic fibrosis
KLIN PADIATR. Abstracts. 2024; 236(02):S10-S10.-45. Jahrestagung der Gesellschaft für Pädiatrische Pneumologie; MAR 14-16, 2024; Bochum, GERMANY. Doi: 10.1055/s-0044-1779367 [Poster]
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** Schaffer, AM; Zimmermann, T; Mallet, MC; Mozun, R; Kuehni, CE; Latzin, P; Usemann, J; Möller, A; Herzog, SA; Singer, F LuftiBus in the school (LUIS): lung function classes and respiratory symptoms in schoolchildren
WIEN KLIN WOCHENSCHR. 2024; 136: S521-S522. [Poster]
Web of Science

 

2023

Full paper/article (Journal)

** Abdel-Aziz, MI; Thorsen, J; Hashimoto, S; Vijverberg, SJH; Neerincx, AH; Brinkman, P; van, Aalderen, W; Stokholm, J; Rasmussen, MA; Roggenbuck-Wedemeyer, M; Vissing, NH; Mortensen, MS; Brejnrod, AD; Fleming, LJ; Murray, CS; Fowler, SJ; Frey, U; Bush, A; Singer, F; Hedlin, G; Nordlund, B; Shaw, DE; Chung, KF; Adcock, IM; Djukanovic, R; Auffray, C; Bansal, AT; Sousa, AR; Wagers, SS; Chawes, BL; Bønnelykke, K; Sørensen, SJ; Kraneveld, AD; Sterk, PJ; Roberts, G; Bisgaard, H; Maitland-van, der, Zee, AH, , U-BIOPRED, Study, Group Oropharyngeal Microbiota Clusters in Children with Asthma or Wheeze Associate with Allergy, Blood Transcriptomic Immune Pathways, and Exacerbation Risk.
Am J Respir Crit Care Med. 2023; 208(2):142-154 Doi: 10.1164/rccm.202211-2107OC
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** Ardura-Garcia, C; Mallet, MC; Berger, DO; Hoyler, K; Jochmann, A; Kuhn, A; Moeller, A; Regamey, N; Singer, F; Pedersen, ESL; Kuehni, CE, , SPAC, Study, Team Predictors of asthma control differ from predictors of asthma attacks in children: The Swiss Paediatric Airway Cohort.
Clin Exp Allergy. 2023; Doi: 10.1111/cea.14390
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** Brandsma, J; Schofield, JPR; Yang, X; Strazzeri, F; Barber, C; Goss, VM; Koster, G; Bakke, PS; Caruso, M; Chanez, P; Dahlén, SE; Fowler, SJ; Horváth, I; Krug, N; Montuschi, P; Sanak, M; Sandström, T; Shaw, DE; Chung, KF; Singer, F; Fleming, LJ; Adcock, IM; Pandis, I; Bansal, AT; Corfield, J; Sousa, AR; Sterk, PJ; Sánchez-García, RJ; Skipp, PJ; Postle, AD; Djukanović, R, , U-BIOPRED, Study, Group Stratification of asthma by lipidomic profiling of induced sputum supernatant.
J Allergy Clin Immunol. 2023; 152(1):117-125 Doi: 10.1016/j.jaci.2023.02.032
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** de, Jong, CCM; Ardura-Garcia, C; Pedersen, ESL; Mallet, MC; Mueller-Suter, D; Jochmann, A; Singer, F; Casaulta, CA; Regamey, N; Moeller, A; Goutaki, M; Kuehni, CE Standardization of Reporting Obstructive Airway Disease in Children: A National Delphi Process.
J Allergy Clin Immunol Pract. 2023; 11(1): 187-194.e6. Doi: 10.1016/j.jaip.2022.08.050
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** Khaleva, E; Rattu, A; Brightling, C; Bush, A; Bossios, A; Bourdin, A; Chung, KF; Chaudhuri, R; Coleman, C; Dahlén, SE; Djukanovic, R; Deschildre, A; Fleming, L; Fowler, SJ; Gupta, A; Hamelmann, E; Hashimoto, S; Hedlin, G; Koppelman, GH; Melén, E; Murray, CS; Pilette, C; Porsbjerg, C; Pike, KC; Rusconi, F; Williams, C; Ahrens, B; Alter, P; Anckers, F; van, den, Berge, M; Blumchen, K; Brusselle, G; Clarke, GW; Cunoosamy, D; Dahlén, B; Dixey, P; Exley, A; Frey, U; Gaillard, EA; Giovannini-Chami, L; Grigg, J; Hartenstein, D; Heaney, LG; Karadag, B; Kaul, S; Kull, I; Licari, A; Maitland-van, der, Zee, AH; Mahler, V; Schoos, AM; Nagakumar, P; Negus, J; Nielsen, H; Paton, J; Pijnenburg, M; Ramiconi, V; Romagosa, Vilarnau, S; Principe, S; Rutjes, N; Saglani, S; Seddon, P; Singer, F; Staudinger, H; Turner, S; Vijverberg, S; Winders, T; Yasinska, V; Roberts, G, , COMSA, Working, Group, in, the, 3TR, Consortium Development of Core Outcome Measures sets for paediatric and adult Severe Asthma (COMSA).
Eur Respir J. 2023; 61(4): 2200606 Doi: 10.1183/13993003.00606-2022 [OPEN ACCESS]
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** Khaleva, E; Rattu, A; Brightling, C; Bush, A; Bourdin, A; Bossios, A; Chung, KF; Chaudhuri, R; Coleman, C; Djukanovic, R; Dahlén, SE; Exley, A; Fleming, L; Fowler, SJ; Gupta, A; Hamelmann, E; Koppelman, GH; Melén, E; Mahler, V; Seddon, P; Singer, F; Porsbjerg, C; Ramiconi, V; Rusconi, F; Yasinska, V; Roberts, G Definitions of non-response and response to biological therapy for severe asthma: a systematic review.
ERJ Open Res. 2023; 9(3): Doi: 10.1183/23120541.00444-2022 [OPEN ACCESS]
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** Mallet, MC; Mozun, R; Ardura-Garcia, C; Pedersen, ESL; Jurca, M; Latzin, P; Moeller, A; Kuehni, CE, , LUIS, Study, Group Phenotypic characteristics, healthcare use, and treatment in children with night cough compared with children with wheeze.
Pediatr Pulmonol. 2023; Doi: 10.1002/ppul.26626
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** Mallet, MC; Mozun, R; Pedersen, ESL; Ardura-Garcia, C; Gaillard, EA; Latzin, P; Moelller, A; Kuehni, CE, , LUIS, study, group, , LUIS, study, group Prevalence of childhood cough in epidemiological studies depends on the question used: findings from two population-based studies.
Swiss Med Wkly. 2023; 153: 40044 Doi: 10.57187/smw.2023.40044
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** Versi, A; Ivan, FX; Abdel-Aziz, MI; Bates, S; Riley, J; Baribaud, F; Kermani, NZ; Montuschi, P; Dahlen, SE; Djukanovic, R; Sterk, P; Maitland-Van, Der, Zee, AH; Chotirmall, SH; Howarth, P; Adcock, IM; Chung, KF, , U-BIOPRED, consortium Haemophilus influenzae and Moraxella catarrhalis in sputum of severe asthma with inflammasome and neutrophil activation.
Allergy. 2023; Doi: 10.1111/all.15776
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** Yasinska, V; Gómez, C; Kolmert, J; Ericsson, M; Pohanka, A; James, A; Andersson, LI; Sparreman-Mikus, M; Sousa, AR; Riley, JH; Bates, S; Bakke, PS; Zounemat, Kermani, N; Caruso, M; Chanez, P; Fowler, SJ; Geiser, T; Howarth, PH; Horváth, I; Krug, N; Montuschi, P; Sanak, M; Behndig, A; Shaw, DE; Knowles, RG; Dahlén, B; Maitland-van, der, Zee, AH; Sterk, PJ; Djukanovic, R; Adcock, IM; Chung, KF; Wheelock, CE; Dahlén, SE; Wikström, Jonsson, E, , U-BIOPRED, Study, Group, Low levels of endogenous anabolic androgenic steroids in females with severe asthma taking corticosteroids.
ERJ Open Res. 2023; 9(5): Doi: 10.1183/23120541.00269-2023 [OPEN ACCESS]
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Abstract (Journal)

** Schlagenhaufen, S; Pfleger, A; Maier, A; Brcic, L; Singer, F; Eber, E A girl with pneumonia and an eye-catching chest x-ray
WIEN KLIN WOCHENSCHR. 2023; 135(19-20): 583-583. [Poster]
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2022

Full paper/article (Journal)

** Ardura-Garcia, C; Pedersen, ESL; Mallet, MC; de, Jong, CCM; Barben, J; Jochmann, A; Jung, A; Mueller-Suter, D; Regamey, N; Singer, F; Kuehni, CE; SPAC Study Team Treatment Decisions in Children With Asthma in a Real-Life Clinical Setting: The Swiss Paediatric Airway Cohort.
J Allergy Clin Immunol Pract. 2022; 10(4):1038-1046.e8 Doi: 10.1016/j.jaip.2021.10.026
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** Badi, YE; Pavel, AB; Pavlidis, S; Riley, JH; Bates, S; Kermani, NZ; Knowles, R; Kolmert, J; Wheelock, CE; Worsley, S; Uddin, M; Alving, K; Bakke, PS; Behndig, A; Caruso, M; Chanez, P; Fleming, LJ; Fowler, SJ; Frey, U; Howarth, P; Horváth, I; Krug, N; Maitland-van, der, Zee, AH; Montuschi, P; Roberts, G; Sanak, M; Shaw, DE; Singer, F; Sterk, PJ; Djukanovic, R; Dahlen, SE; Guo, YK; Chung, KF; Guttman-Yassky, E; Adcock, IM, , U-BIOPRED, Study, Group Mapping atopic dermatitis and anti-IL-22 response signatures to type 2-low severe neutrophilic asthma.
J Allergy Clin Immunol. 2022; 149(1):89-101 Doi: 10.1016/j.jaci.2021.04.010
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** Berger, DO; Pedersen, ESL; Mallet, MC; de, Jong, CCM; Usemann, J; Regamey, N; Spycher, BD; Ardura-Garcia, C; Kuehni, CE, , SPAC, Study, Team External validation of the Predicting Asthma Risk in Children tool in a clinical cohort.
Pediatr Pulmonol. 2022; 57(11): 2715-2723. Doi: 10.1002/ppul.26088 [OPEN ACCESS]
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** Hoda, U; Pavlidis, S; Bansal, AT; Takahashi, K; Hu, S; Ng, Kee, Kwong, F; Rossios, C; Sun, K; Bhavsar, P; Loza, M; Baribaud, F; Chanez, P; Fowler, SJ; Horvath, I; Montuschi, P; Singer, F; Musial, J; Dahlen, B; Krug, N; Sandstrom, T; Shaw, DE; Lutter, R; Fleming, LJ; Howarth, PH; Caruso, M; Sousa, AR; Corfield, J; Auffray, C; De, Meulder, B; Lefaudeux, D; Dahlen, SE; Djukanovic, R; Sterk, PJ; Guo, Y; Adcock, IM; Chung, KF, , U-BIOPRED, study, group Clinical and transcriptomic features of persistent exacerbation-prone severe asthma in U-BIOPRED cohort.
Clin Transl Med. 2022; 12(4):e816 Doi: 10.1002/ctm2.816 [OPEN ACCESS]
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** Kurz, JM; Ramsey, KA; Rodriguez, R; Spycher, B; Fischer, Biner, R; Latzin, P; Singer, F Association of lung clearance index with survival in individuals with cystic fibrosis.
Eur Respir J. 2022; 59(3): Doi: 10.1183/13993003.00432-2021
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** Mozun, R; Ardura-Garcia, C; Pedersen, ESL; Usemann, J; Singer, F; Latzin, P; Moeller, A; Kuehni, CE Age and body mass index affect fit of spirometry Global Lung Function Initiative references in schoolchildren.
ERJ Open Res. 2022; 8(2): Doi: 10.1183/23120541.00618-2021 [OPEN ACCESS]
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** Nyilas, S; Bauman, G; Korten, I; Pusterla, O; Singer, F; Ith, M; Groen, C; Schoeni, A; Heverhagen, JT; Christe, A; Rodondi, N; Bieri, O; Geiser, T; Auer, R; Funke-Chambour, M; Ebner, L MRI Shows Lung Perfusion Changes after Vaping and Smoking.
Radiology. 2022; 304(1): 195-204. Doi: 10.1148/radiol.211327
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** Reinke, SN; Naz, S; Chaleckis, R; Gallart-Ayala, H; Kolmert, J; Kermani, NZ; Tiotiu, A; Broadhurst, DI; Lundqvist, A; Olsson, H; Ström, M; Wheelock, ÅM; Gómez, C; Ericsson, M; Sousa, AR; Riley, JH; Bates, S; Scholfield, J; Loza, M; Baribaud, F; Bakke, PS; Caruso, M; Chanez, P; Fowler, SJ; Geiser, T; Howarth, P; Horváth, I; Krug, N; Montuschi, P; Behndig, A; Singer, F; Musial, J; Shaw, DE; Dahlén, B; Hu, S; Lasky-Su, J; Sterk, PJ; Chung, KF; Djukanovic, R; Dahlén, SE; Adcock, IM; Wheelock, CE, , U-BIOPRED, Study, Group Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study.
Eur Respir J. 2022; 59(6): Doi: 10.1183/13993003.01733-2021 [OPEN ACCESS]
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** Thorsen, J; Stokholm, J; Rasmussen, MA; Roggenbuck-Wedemeyer, M; Vissing, NH; Mortensen, MS; Brejnrod, AD; Fleming, L; Bush, A; Roberts, G; Singer, F; Frey, U; Hedlin, G; Nordlund, B; Murray, CS; Abdel-Aziz, MI; Hashimoto, S; van, Aalderen, W; Maitland-van, der, Zee, AH; Shaw, D; Fowler, SJ; Sousa, A; Sterk, PJ; Chung, KF; Adcock, IM; Djukanovic, R; Auffray, C; Bansal, AT; Wagers, S; Chawes, B; Bønnelykke, K; Sørensen, SJ; Bisgaard, H Asthma and Wheeze Severity and the Oropharyngeal Microbiota in Children and Adolescents.
Ann Am Thorac Soc. 2022; 19(12):2031-2043 Doi: 10.1513/AnnalsATS.202110-1152OC
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Short report/Letter

** Kentgens, AC; Latzin, P; Anagnostopoulou, P; Jensen, R; Stahl, M; Harper, A; Yammine, S; Foong, RE; Hall, GL; Singer, F; Stanojevic, S; Mall, MA; Ratjen, F; Ramsey, KA Normative multiple-breath washout data in school-aged children corrected for sensor error.
Eur Respir J. 2022; 60(2): Doi: 10.1183/13993003.02398-2021
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Abstract (Journal)

** Abdel-Aziz, MI; Thorsen, J; Hashimoto, S; Vijverberg, SJH; Neerincx, AH; Brinkman, P; Aalderen, W; Stokholm, J; Roggenbuck-Wedemeyer, M; Vissing, NH; Mortensen, MS; Brejnrod, AD; Fleming, LJ; Murray, CS; Fowler, SJ; Frey, U; Bush, A; Singer, F; Hedlin, G; Nordlund, B; Shaw, E; Chung, KF; Adcock, IM; Djukanovic, R; Auffray, C; Bansal, AT; Sousa, AR; Wagers, SS; Chawes, BL; Bønnelykke, K; Sørensen, SJ; Kraneveld, AD; Sterk, PJ; Roberts, G; Bisgaard, H; Maitland-Van Der Zee, AH Identification of oropharyngeal microbiome-driven asthma and wheezing clusters in children
European Respiratory Journal. 2022; 60(66):-ERS International Congress ; SEP 4-6, 2022; Barcelona, SPAIN. Doi: 10.1183/13993003.congress-2022.688 [Oral Communication]
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** Ardura-Garcia, C; Mallet, MC; Berger, DO; Pedersen, ESL; Hoyler, K; Jochmann, A; Kuhn, A; Moeller, A; Regamey, N; Singer, F; Kuehni, CE Predictors of suboptimal asthma control and of asthma attacks differ: the Swiss Paediatric Airway Cohort (SPAC).
European Respiratory Journal. 2022; 60(66):-ERS International Congress 2022; SEP 4-6, 2022; Barcelona, SPAIN. Doi: 10.1183/13993003.congress-2022.3283 [Oral Communication]
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** Kentgens, AC; Kurz, JM; Mozun, R; Pedersen, ESL; Usemann, J; Kuehni, CE; Latzin, P; Moeller, A; Singer, F Alterations in ventilation inhomogeneity in school-aged children with wheeze - the LUftibus in the school study (LUIS)
KLIN PADIATR. 2022; 234(05):328-328.-43. Jahrestagung der Gesellschaft für Pädiatrische Pneumologie; SEPT 28-30, 2022; Bern, Schweiz. Doi: 10.1055/s-0042-1754478
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** Usemann, J; Mozun, R; Kuehni, C; De Hoog, K; Singer, F; Möller, A; Latzin, P Exposure to air pollution and lung development during childhood: the LUIS Study.
European Respiratory Journal. 2022; 60(66):-ERS International Congress 2022 ; SEP 4-6, 2022; Barcelona, SPAIN. Doi: 10.1183/13993003.congress-2022.2338 [Oral Communication]
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** Usemann, J; Mozún, R; Kuehni, CE; de Hoogh, K; Flückinger, B; Singer, F; Moeller, A; Latzin, P Air pollution exposure during pregnancy and lung development during childhood: the LUIS study.
Klinische Pädiatrie. 2022; 234(5):328--43. Jahrestagung der Gesellschaft für Pädiatrische Pneumologie; SEP 28-30, 2022; Bern, SWITZERLAND. Doi: 10.1055/s-0042-1754477 [Onlinepräsentation]
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Comment

** Mozun, R; Berger, F; Singer, F One size does not fit all-Why do pediatric spirometry estimates vary across populations "down under"?
Pediatr Pulmonol. 2022; 57(2):345-346 Doi: 10.1002/ppul.25751
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2021

Full paper/article (Journal)

** Alahmadi, FH; Simpson, AJ; Gomez, C; Ericsson, M; Thörngren, JO; Wheelock, CE; Shaw, DE; Fleming, LJ; Roberts, G; Riley, J; Bates, S; Sousa, AR; Knowles, R; Bansal, AT; Corfield, J; Pandis, I; Sun, K; Bakke, PS; Caruso, M; Chanez, P; Dahlén, B; Horvath, I; Krug, N; Montuschi, P; Singer, F; Wagers, S; Adcock, IM; Djukanovic, R; Chung, KF; Sterk, PJ; Dahlen, SE; Fowler, SJ, , U-BIOPRED, Study, Group Medication Adherence in Patients With Severe Asthma Prescribed Oral Corticosteroids in the U-BIOPRED Cohort.
Chest. 2021; 160(1):53-64 Doi: 10.1016/j.chest.2021.02.023
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** Bernasconi, N; Kieninger, E; Shaw, M; Kurz, J; Moeller, A; Ratjen, F; Rochat, I; Stanojevic, S; Singer, F CFTR-function and ventilation inhomogeneity in individuals with cystic fibrosis.
J Cyst Fibros. 2021; 20(4):641-647 Doi: 10.1016/j.jcf.2020.12.009
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** Kolmert, J; Gómez, C; Balgoma, D; Sjödin, M; Bood, J; Konradsen, JR; Ericsson, M; Thörngren, JO; James, A; Mikus, M; Sousa, AR; Riley, JH; Bates, S; Bakke, PS; Pandis, I; Caruso, M; Chanez, P; Fowler, SJ; Geiser, T; Howarth, P; Horváth, I; Krug, N; Montuschi, P; Sanak, M; Behndig, A; Shaw, DE; Knowles, RG; Holweg, CTJ; Wheelock, ÅM; Dahlén, B; Nordlund, B; Alving, K; Hedlin, G; Chung, KF; Adcock, IM; Sterk, PJ; Djukanovic, R; Dahlén, SE; Wheelock, CE, , U-BIOPRED, Study, Group, on, behalf, of, the, U-BIOPRED, Study, Group Urinary Leukotriene E4 and Prostaglandin D2 Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation. A Clinical Observational Study.
Am J Respir Crit Care Med. 2021; 203(1):37-53 Doi: 10.1164/rccm.201909-1869OC [OPEN ACCESS]
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** Korten, I; Oestreich, MA; Frey, U; Moeller, A; Jung, A; Spinas, R; Mueller-Suter, D; Trachsel, D; Rochat, I; Spycher, B; Latzin, P; Casaulta, C; Ramsey, K, , SCILD, and, BILD, study, group Respiratory symptoms do not reflect functional impairment in early CF lung disease.
J Cyst Fibros. 2021; 20(6):957-964 Doi: 10.1016/j.jcf.2021.04.006
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** Mozun, R; Ardura-Garcia, C; Pedersen, ESL; Goutaki, M; Usemann, J; Singer, F; Latzin, P; Moeller, A; Kuehni, CE, , LUIS, study, group Agreement of parent- and child-reported wheeze and its association with measurable asthma traits.
Pediatr Pulmonol. 2021; 56(12):3813-3821 Doi: 10.1002/ppul.25690 [OPEN ACCESS]
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** Mozun, R; Kuehni, CE; Pedersen, ESL; Goutaki, M; Kurz, JM; de, Hoogh, K; Usemann, J; Singer, F; Latzin, P; Moeller, A; On, Behalf, Of, The, Luis, Study, Group LuftiBus in the school (LUIS): a population-based study on respiratory health in schoolchildren.
Swiss Med Wkly. 2021; 151:w20544 Doi: 10.4414/smw.2021.20544
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** Pedersen, ESL; Ardura-Garcia, C; de, Jong, CCM; Jochmann, A; Moeller, A; Mueller-Suter, D; Regamey, N; Singer, F; Goutaki, M; Kuehni, CE Diagnosis in children with exercise-induced respiratory symptoms: A multi-center study.
Pediatr Pulmonol. 2021; 56(1):217-225 Doi: 10.1002/ppul.25126
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** Pedersen, ESL; de, Jong, CCM; Ardura-Garcia, C; Mallet, MC; Barben, J; Casaulta, C; Hoyler, K; Jochmann, A; Moeller, A; Mueller-Suter, D; Regamey, N; Singer, F; Goutaki, M; Kuehni, CE Reported Symptoms Differentiate Diagnoses in Children with Exercise-Induced Respiratory Problems: Findings from the Swiss Paediatric Airway Cohort (SPAC).
J Allergy Clin Immunol Pract. 2021; 9(2):881-889.e3 Doi: 10.1016/j.jaip.2020.09.012
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** Singer, F; Schlegtendal, A; Nyilas, S; Vermeulen, F; Boon, M; Koerner-Rettberg, C Lung clearance index predicts pulmonary exacerbations in individuals with primary ciliary dyskinesia: a multicentre cohort study.
Thorax. 2021; 76(7):681-688 Doi: 10.1136/thoraxjnl-2020-215504
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Short report/Letter

** Gorlanova, O; Tischhauser, E; Adcock, IM; Chung, KF; Fleming, L; Meier, D; Sterk, PJ; Roberts, G; Roberts, A; Singer, F; Sousa, AR; Uddin, M; Frey, U, , U-BIOPRED, Study, Group Discordant use of short-acting β2 agonists in children and adults with severe, uncontrolled asthma from the U-BIOPRED cohort.
Pediatr Pulmonol. 2021; 56(2):338-340 Doi: 10.1002/ppul.25171
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** Kurz, JM; Frey, J; Auer, R; Rodondi, N; Nyilas, S; Pavlov, N; Funke-Chambour, M; Singer, F Influence of ventilation inhomogeneity on diffusing capacity of carbon monoxide in smokers without COPD.
ERJ Open Res. 2021; 7(1): Doi: 10.1183/23120541.00706-2020 [OPEN ACCESS]
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2020

Full paper/article (Journal)

** Abdel-Aziz, MI; Brinkman, P; Vijverberg, SJH; Neerincx, AH; de, Vries, R; Dagelet, YWF; Riley, JH; Hashimoto, S; Montuschi, P; Chung, KF; Djukanovic, R; Fleming, LJ; Murray, CS; Frey, U; Bush, A; Singer, F; Hedlin, G; Roberts, G; Dahlén, SE; Adcock, IM; Fowler, SJ; Knipping, K; Sterk, PJ; Kraneveld, AD; Maitland-van, der, Zee, AH, , U-BIOPRED, Study, Group;Amsterdam, UMC, Breath, Research, Group eNose breath prints as a surrogate biomarker for classifying patients with asthma by atopy.
J Allergy Clin Immunol. 2020; 146(5):1045-1055 Doi: 10.1016/j.jaci.2020.05.038
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** Anagnostopoulou, P; Latzin, P; Jensen, R; Stahl, M; Harper, A; Yammine, S; Usemann, J; Foong, RE; Spycher, B; Hall, GL; Singer, F; Stanojevic, S; Mall, MA; Ratjen, F; Ramsey, KA Normative data for multiple breath washout outcomes in school-aged Caucasian children.
Eur Respir J. 2020; 55(4): Doi: 10.1183/13993003.01302-2019
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** Cruz, AA; Riley, JH; Bansal, AT; Ponte, EV; Souza-Machado, A; Almeida, PCA; Biao-Lima, V; Davis, M; Bates, S; Adcock, IM; Sterk, PJ; Chung, KF, , ProAR, Study, Group;U-BIOPRED, Study, Groups, , ProAR, Study, Group;U-BIOPRED, Study, Groups Asthma similarities across ProAR (Brazil) and U-BIOPRED (Europe) adult cohorts of contrasting locations, ethnicity and socioeconomic status.
Respir Med. 2020; 161:105817 Doi: 10.1016/j.rmed.2019.105817
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** de, Jong, CCM; Pedersen, ESL; Mozun, R; Müller-Suter, D; Jochmann, A; Singer, F; Casaulta, C; Regamey, N; Moeller, A; Ardura-Garcia, C; Kuehni, CE Diagnosis of asthma in children: findings from the Swiss Paediatric Airway Cohort.
Eur Respir J. 2020; 56(5): Doi: 10.1183/13993003.00132-2020
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** Isaac, SM; Jensen, R; Anagnostopoulou, P; Davies, JC; Gappa, M; Latzin, P; Saunders, C; Short, C; Singer, F; Stanojevic, S; Zwitserloot, A; Ratjen, F Evaluation of a multiple breath nitrogen washout system in children.
Pediatr Pulmonol. 2020; 55(8):2108-2114 Doi: 10.1002/ppul.24862
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** Mozun, R; Ardura-Garcia, C; de, Jong, CCM; Goutaki, M; Usemann, J; Singer, F; Latzin, P; Kuehni, CE; Moeller, A Cigarette, shisha, and electronic smoking and respiratory symptoms in Swiss children: The LUIS study.
Pediatr Pulmonol. 2020; 55(10):2806-2815 Doi: 10.1002/ppul.24985
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** Roberts, G; Fontanella, S; Selby, A; Howard, R; Filippi, S; Hedlin, G; Nordlund, B; Howarth, P; Hashimoto, S; Brinkman, P; Fleming, LJ; Murray, C; Bush, A; Frey, U; Singer, F; Schoos, AM; van, Aalderen, W; Djukanovic, R; Chung, KF; Sterk, PJ; Adnan, C, , U-BIOPRED, Consortium Connectivity patterns between multiple allergen specific IgE antibodies and their association with severe asthma.
J Allergy Clin Immunol. 2020; 146(4):821-830 Doi: 10.1016/j.jaci.2020.02.031
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2019

Full paper/article (Journal)

** Anagnostopoulou, P; Vomsattel, S; Kentgens, AC; Guidi, M; Binggeli, S; Kohler, L; Singer, F; Latzin, P; Obrist, D An innovative lung model for multiple breath washout testing in health and disease.
Clin Biomech (Bristol, Avon). 2019; 66:74-80 Doi: 10.1016/j.clinbiomech.2017.11.002
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** Jevnikar, Z; Östling, J; Ax, E; Calvén, J; Thörn, K; Israelsson, E; Öberg, L; Singhania, A; Lau, LCK; Wilson, SJ; Ward, JA; Chauhan, A; Sousa, AR; De, Meulder, B; Loza, MJ; Baribaud, F; Sterk, PJ; Chung, KF; Sun, K; Guo, Y; Adcock, IM; Payne, D; Dahlen, B; Chanez, P; Shaw, DE; Krug, N; Hohlfeld, JM; Sandström, T; Djukanovic, R; James, A; Hinks, TSC; Howarth, PH; Vaarala, O; van, Geest, M; Olsson, H, , Unbiased, Biomarkers, in, Prediction, of, Respiratory, Disease, Outcomes, study, group Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation.
J Allergy Clin Immunol. 2019; 143(2):577-590 Doi: 10.1016/j.jaci.2018.05.026
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** Korten, I; Kieninger, E; Yammine, S; Cangiano, G; Nyilas, S; Anagnostopoulou, P; Singer, F; Kuehni, CE; Regamey, N; Frey, U; Casaulta, C; Spycher, BD; Latzin, P, , SCILD;BILD, study, group Respiratory rate in infants with cystic fibrosis throughout the first year of life and association with lung clearance index measured shortly after birth.
J Cyst Fibros. 2019; 18(1):118-126 Doi: 10.1016/j.jcf.2018.07.002
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** Nyilas, S; Bauman, G; Pusterla, O; Ramsey, K; Singer, F; Stranzinger, E; Yammine, S; Casaulta, C; Bieri, O; Latzin, P Ventilation and perfusion assessed by functional MRI in children with CF: reproducibility in comparison to lung function.
J Cyst Fibros. 2019; 18(4):543-550 Doi: 10.1016/j.jcf.2018.10.003
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** Östling, J; van, Geest, M; Schofield, JPR; Jevnikar, Z; Wilson, S; Ward, J; Lutter, R; Shaw, DE; Bakke, PS; Caruso, M; Dahlen, SE; Fowler, SJ; Horváth, I; Krug, N; Montuschi, P; Sanak, M; Sandström, T; Sun, K; Pandis, I; Auffray, C; Sousa, AR; Guo, Y; Adcock, IM; Howarth, P; Chung, KF; Bigler, J; Sterk, PJ; Skipp, PJ; Djukanović, R; Vaarala, O, , U-BIOPRED, Study, Group IL-17-high asthma with features of a psoriasis immunophenotype.
J Allergy Clin Immunol. 2019; 144(5):1198-1213 Doi: 10.1016/j.jaci.2019.03.027
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** Stöberl, AS; Gaisl, T; Giunta, C; Sievi, NA; Singer, F; Möller, A; Rohrbach, M; Kohler, M Obstructive Sleep Apnoea in Children and Adolescents with Ehlers-Danlos Syndrome.
Respiration. 2019; 97(4): 284-291. Doi: 10.1159/000494328
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Short report/Letter

** Perotin, JM; Schofield, JPR; Wilson, SJ; Ward, J; Brandsma, J; Strazzeri, F; Bansal, A; Yang, X; Rowe, A; Corfield, J; Lutter, R; Shaw, DE; Bakke, PS; Caruso, M; Dahlén, B; Fowler, SJ; Horváth, I; Howarth, P; Krug, N; Montuschi, P; Sanak, M; Sandström, T; Sun, K; Pandis, I; Auffray, C; De, Meulder, B; Lefaudeux, D; Riley, JH; Sousa, AR; Dahlen, SE; Adcock, IM; Chung, KF; Sterk, PJ; Skipp, PJ; Collins, JE; Davies, DE; Djukanović, R, , U-BIOPRED, Study, Group;U-BIOPRED: Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux.
Eur Respir J. 2019; 53(6): Doi: 10.1183/13993003.00453-2019 [OPEN ACCESS]
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** Simpson, AJ; Hekking, PP; Shaw, DE; Fleming, LJ; Roberts, G; Riley, JH; Bates, S; Sousa, AR; Bansal, AT; Pandis, I; Sun, K; Bakke, PS; Caruso, M; Dahlén, B; Dahlén, SE; Horvath, I; Krug, N; Montuschi, P; Sandstrom, T; Singer, F; Adcock, IM; Wagers, SS; Djukanovic, R; Chung, KF; Sterk, PJ; Fowler, SJ, , U-BIOPRED, Study, Group Treatable traits in the European U-BIOPRED adult asthma cohorts.
Allergy. 2019; 74(2):406-411 Doi: 10.1111/all.13629 [OPEN ACCESS]
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2018

Full paper/article (Journal)

** Anagnostopoulou, P; Kranz, N; Wolfensberger, J; Guidi, M; Nyilas, S; Koerner-Rettberg, C; Yammine, S; Singer, F; Latzin, P Comparison of different analysis algorithms to calculate multiple-breath washout outcomes.
ERJ Open Res. 2018; 4(3): Doi: 10.1183/23120541.00021-2017 [OPEN ACCESS]
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** Brandsma, J; Goss, VM; Yang, X; Bakke, PS; Caruso, M; Chanez, P; Dahlén, SE; Fowler, SJ; Horvath, I; Krug, N; Montuschi, P; Sanak, M; Sandström, T; Shaw, DE; Chung, KF; Singer, F; Fleming, LJ; Sousa, AR; Pandis, I; Bansal, AT; Sterk, PJ; Djukanović, R; Postle, AD, , U-BIOPRED, Study, Group Lipid phenotyping of lung epithelial lining fluid in healthy human volunteers.
Metabolomics. 2018; 14(10):123 Doi: 10.1007/s11306-018-1412-2 [OPEN ACCESS]
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** Burg, D; Schofield, JPR; Brandsma, J; Staykova, D; Folisi, C; Bansal, A; Nicholas, B; Xian, Y; Rowe, A; Corfield, J; Wilson, S; Ward, J; Lutter, R; Fleming, L; Shaw, DE; Bakke, PS; Caruso, M; Dahlen, SE; Fowler, SJ; Hashimoto, S; Horváth, I; Howarth, P; Krug, N; Montuschi, P; Sanak, M; Sandström, T; Singer, F; Sun, K; Pandis, I; Auffray, C; Sousa, AR; Adcock, IM; Chung, KF; Sterk, PJ; Djukanović, R; Skipp, PJ; The, U-Biopred, Study, Group Large-Scale Label-Free Quantitative Mapping of the Sputum Proteome.
J Proteome Res. 2018; 17(6):2072-2091 Doi: 10.1021/acs.jproteome.8b00018
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** Emma, R; Bansal, AT; Kolmert, J; Wheelock, CE; Dahlen, SE; Loza, MJ; De, Meulder, B; Lefaudeux, D; Auffray, C; Dahlen, B; Bakke, PS; Chanez, P; Fowler, SJ; Horvath, I; Montuschi, P; Krug, N; Sanak, M; Sandstrom, T; Shaw, DE; Fleming, LJ; Djukanovic, R; Howarth, PH; Singer, F; Sousa, AR; Sterk, PJ; Corfield, J; Pandis, I; Chung, KF; Adcock, IM; Lutter, R; Fabbella, L; Caruso, M, , U-BIOPRED, Study, Group Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort.
PLoS One. 2018; 13(9):e0203874 Doi: 10.1371/journal.pone.0203874 [OPEN ACCESS]
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** Gaisl, T; Bregy, L; Stebler, N; Gaugg, MT; Bruderer, T; García-Gómez, D; Moeller, A; Singer, F; Schwarz, EI; Benden, C; M-L, Sinues, P; Zenobi, R; Kohler, M Real-time exhaled breath analysis in patients with cystic fibrosis and controls.
J Breath Res. 2018; 12(3):036013 Doi: 10.1088/1752-7163/aab7fd
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** Hekking, PP; Loza, MJ; Pavlidis, S; de, Meulder, B; Lefaudeux, D; Baribaud, F; Auffray, C; Wagener, AH; Brinkman, P; Lutter, R; Bansal, AT; Sousa, AR; Bates, SA; Pandis, Y; Fleming, LJ; Shaw, DE; Fowler, SJ; Guo, Y; Meiser, A; Sun, K; Corfield, J; Howarth, PH; Bel, EH; Adcock, IM; Chung, KF; Djukanovic, R; Sterk, PJ, , U-BIOPRED, Study, Group, , U-BIOPRED, Study, Group Pathway discovery using transcriptomic profiles in adult-onset severe asthma.
J Allergy Clin Immunol. 2018; 141(4):1280-1290 Doi: 10.1016/j.jaci.2017.06.037
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** Kasteler, R; Kam, LMH; Weiss, A; Waespe, N; Sommer, G; Singer, F; von, der, Weid, NX; Ansari, M; Kuehni, CE, , Swiss, Pediatric, Oncology, Group, (SPOG) Monitoring pulmonary health in Swiss childhood cancer survivors.
Pediatr Blood Cancer. 2018; 65(10):e27255 Doi: 10.1002/pbc.27255
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** Kentgens, AC; Guidi, M; Korten, I; Kohler, L; Binggeli, S; Singer, F; Latzin, P; Anagnostopoulou, P Infant multiple breath washout using a new commercially available device: Ready to replace the previous setup?
Pediatr Pulmonol. 2018; 53(5):628-635 Doi: 10.1002/ppul.23959
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** Korten, I; Liechti, M; Singer, F; Hafen, G; Rochat, I; Anagnostopoulou, P; Müller-Suter, D; Usemann, J; Moeller, A; Frey, U; Latzin, P; Casaulta, C, , SCILD, and, BILD, study, group Lower exhaled nitric oxide in infants with Cystic Fibrosis compared to healthy controls.
J Cyst Fibros. 2018; 17(1):105-108 Doi: 10.1016/j.jcf.2017.05.005
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** Lenherr, N; Ramsey, KA; Jost, K; Hornwall, L; Singer, F; Yammine, S; Latzin, P Leaks during multiple-breath washout: characterisation and influence on outcomes.
ERJ Open Res. 2018; 4(1): Doi: 10.1183/23120541.00012-2017 [OPEN ACCESS]
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** Nyilas, S; Bauman, G; Pusterla, O; Sommer, G; Singer, F; Stranzinger, E; Heyer, C; Ramsey, K; Schlegtendal, A; Benzrath, S; Casaulta, C; Goutaki, M; Kuehni, CE; Bieri, O; Koerner-Rettberg, C; Latzin, P Structural and Functional Lung Impairment in Primary Ciliary Dyskinesia. Assessment with Magnetic Resonance Imaging and Multiple Breath Washout in Comparison to Spirometry.
Ann Am Thorac Soc. 2018; 15(12):1434-1442 Doi: 10.1513/AnnalsATS.201712-967OC
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** Nyilas, S; Baumeler, L; Tamm, M; Halter, JP; Savic, S; Korten, I; Meyer, A; Singer, F; Passweg, JR; Latzin, P; Stolz, D Inert Gas Washout in Bronchiolitis Obliterans Following Hematopoietic Cell Transplantation.
Chest. 2018; 154(1):157-168 Doi: 10.1016/j.chest.2017.12.009
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** Nyilas, S; Bigler, A; Yammine, S; Kieninger, E; Rochat, I; Ramsey, K; Casaulta, C; Moeller, A; Latzin, P; Singer, F Alternate gas washout indices: Assessment of ventilation inhomogeneity in mild to moderate pediatric cystic fibrosis lung disease.
Pediatr Pulmonol. 2018; 53(11):1485-1491 Doi: 10.1002/ppul.24149
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** Nyilas, S; Carlens, J; Price, T; Singer, F; Müller, C; Hansen, G; Warnecke, G; Latzin, P; Schwerk, N Multiple breath washout in pediatric patients after lung transplantation.
Am J Transplant. 2018; 18(1):145-153 Doi: 10.1111/ajt.14432
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** Pedersen, ESL; de, Jong, CCM; Ardura-Garcia, C; Barben, J; Casaulta, C; Frey, U; Jochmann, A; Latzin, P; Moeller, A; Regamey, N; Singer, F; Spycher, B; Sutter, O; Goutaki, M; Kuehni, CE The Swiss Paediatric Airway Cohort (SPAC).
ERJ Open Res. 2018; 4(4): Doi: 10.1183/23120541.00050-2018 [OPEN ACCESS]
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** Roethlisberger, K; Nyilas, S; Riedel, T; Wolfensberger, J; Singer, F; Latzin, P Short-Term Effects of Elastic Chest Wall Restriction on Pulmonary Function in Children with Cystic Fibrosis.
Respiration. 2018; 96(6): 535-542. Doi: 10.1159/000491094
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** Takahashi, K; Pavlidis, S; Ng, Kee, Kwong, F; Hoda, U; Rossios, C; Sun, K; Loza, M; Baribaud, F; Chanez, P; Fowler, SJ; Horvath, I; Montuschi, P; Singer, F; Musial, J; Dahlen, B; Dahlen, SE; Krug, N; Sandstrom, T; Shaw, DE; Lutter, R; Bakke, P; Fleming, LJ; Howarth, PH; Caruso, M; Sousa, AR; Corfield, J; Auffray, C; De, Meulder, B; Lefaudeux, D; Djukanovic, R; Sterk, PJ; Guo, Y; Adcock, IM; Chung, KF, , , on, behalf, of, the, U-BIOPRED, study, group Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis.
Eur Respir J. 2018; 51(5): Doi: 10.1183/13993003.02173-2017
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Comment

** Singer, F; Ramsey, K; Latzin, P Effect of intermittent inspiratory leaks on measurement of lung clearance index using nitrogen and sulfur hexafluoride.
ERJ Open Res. 2018; 4(4): Doi: 10.1183/23120541.00140-2018 [OPEN ACCESS]
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Guideline

** Robinson, PD; Latzin, P; Ramsey, KA; Stanojevic, S; Aurora, P; Davis, SD; Gappa, M; Hall, GL; Horsley, A; Jensen, R; Lum, S; Milla, C; Nielsen, KG; Pittman, JE; Rosenfeld, M; Singer, F; Subbarao, P; Gustafsson, PM; Ratjen, F, , ATS, Assembly, on, Pediatrics Preschool Multiple-Breath Washout Testing. An Official American Thoracic Society Technical Statement.
Am J Respir Crit Care Med. 2018; 197(5):e1-e19 Doi: 10.1164/rccm.201801-0074ST
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2017

Full paper/article (Journal)

** Kieninger, E; Yammine, S; Korten, I; Anagnostopoulou, P; Singer, F; Frey, U; Mornand, A; Zanolari, M; Rochat, I; Trachsel, D; Mueller-Suter, D; Moeller, A; Casaulta, C; Latzin, P, , SCILD, study, group;BILD, study, group Elevated lung clearance index in infants with cystic fibrosis shortly after birth.
Eur Respir J. 2017; 50(5): Doi: 10.1183/13993003.00580-2017
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** Lefaudeux, D; De, Meulder, B; Loza, MJ; Peffer, N; Rowe, A; Baribaud, F; Bansal, AT; Lutter, R; Sousa, AR; Corfield, J; Pandis, I; Bakke, PS; Caruso, M; Chanez, P; Dahlén, SE; Fleming, LJ; Fowler, SJ; Horvath, I; Krug, N; Montuschi, P; Sanak, M; Sandstrom, T; Shaw, DE; Singer, F; Sterk, PJ; Roberts, G; Adcock, IM; Djukanovic, R; Auffray, C; Chung, KF, , U-BIOPRED, Study, Group U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics.
J Allergy Clin Immunol. 2017; 139(6):1797-1807 Doi: 10.1016/j.jaci.2016.08.048
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** Nyilas, S; Bauman, G; Sommer, G; Stranzinger, E; Pusterla, O; Frey, U; Korten, I; Singer, F; Casaulta, C; Bieri, O; Latzin, P Novel magnetic resonance technique for functional imaging of cystic fibrosis lung disease.
Eur Respir J. 2017; 50(6): Doi: 10.1183/13993003.01464-2017
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** Nyilas, S; Schlegtendal, A; Singer, F; Goutaki, M; Kuehni, CE; Casaulta, C; Latzin, P; Koerner-Rettberg, C Alternative inert gas washout outcomes in patients with primary ciliary dyskinesia.
Eur Respir J. 2017; 49(1): Doi: 10.1183/13993003.00466-2016
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** Poncin, W; Singer, F; Aubriot, AS; Lebecque, P Agreement between multiple-breath nitrogen washout systems in children and adults.
J Cyst Fibros. 2017; 16(2):258-266 Doi: 10.1016/j.jcf.2016.11.004
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** Port, J; Tao, Z; Junger, A; Joppek, C; Tempel, P; Husemann, K; Singer, F; Latzin, P; Yammine, S; Nagel, JH; Kohlhäufl, M A simple method to reconstruct the molar mass signal of respiratory gas to assess small airways with a double-tracer gas single-breath washout.
Med Biol Eng Comput. 2017; 55(11):1975-1987 Doi: 10.1007/s11517-017-1633-y
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Short report/Letter

** Kentgens, AC; Anagnostopoulou, P; Singer, F; Latzin, P Unexpected results in infant multiple breath washout: Is the truth hidden in the washin?
Pediatr Pulmonol. 2017; 52(6):717-719 Doi: 10.1002/ppul.23655
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Review

** Usemann, J; Yammine, S; Singer, F; Latzin, P Inert gas washout: background and application in various lung diseases.
Swiss Med Wkly. 2017; 147:w14483 Doi: 10.4414/smw.2017.14483
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Comment

** Jost, K; Egger, B; Kieninger, E; Singer, F; Frey, U; Latzin, P Changes in minute ventilation after exposure to 4% sulfur hexafluoride (SF6 ) in infants.
Pediatr Pulmonol. 2017; 52(2):151-153 Doi: 10.1002/ppul.23557
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2016

Full paper/article (Journal)

** Egger, B; Jost, K; Anagnostopoulou, P; Yammine, S; Singer, F; Casaulta, C; Frey, U; Latzin, P Lung clearance index and moment ratios at different cut-off values in infant multiple-breath washout measurements.
Pediatr Pulmonol. 2016; 51(12):1373-1381 Doi: 10.1002/ppul.23483
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** Jost, K; Lenherr, N; Singer, F; Schulzke, SM; Frey, U; Latzin, P; Yammine, S Changes in breathing pattern upon 100% oxygen in children at early school age.
Respir Physiol Neurobiol. 2016; 228:9-15 Doi: 10.1016/j.resp.2016.03.006
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** Loza, MJ; Djukanovic, R; Chung, KF; Horowitz, D; Ma, K; Branigan, P; Barnathan, ES; Susulic, VS; Silkoff, PE; Sterk, PJ; Baribaud, F, , ADEPT, (Airways, Disease, Endotyping, for, Personalized, Therapeutics), and, U-BIOPRED, (Unbiased, Biomarkers, for, the, Prediction, of, Respiratory, Disease, Outcome, Consortium), investigators Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study.
Respir Res. 2016; 17(1):165 Doi: 10.1186/s12931-016-0482-9 [OPEN ACCESS]
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** Nyilas, S; Singer, F; Kumar, N; Yammine, S; Meier-Girard, D; Koerner-Rettberg, C; Casaulta, C; Frey, U; Latzin, P Physiological phenotyping of pediatric chronic obstructive airway diseases.
J Appl Physiol (1985). 2016; 121(1):324-32 Doi: 10.1152/japplphysiol.00086.2016
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** Yammine, S; Schmidt, A; Sutter, O; Fouzas, S; Singer, F; Frey, U; Latzin, P Functional evidence for continued alveolarisation in former preterms at school age?
Eur Respir J. 2016; 47(1):147-55 Doi: 10.1183/13993003.00478-2015
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** Yammine, S; Summermatter, S; Singer, F; Lauener, R; Latzin, P Feasibility of nitrogen multiple-breath washout in inexperienced children younger than 7 years.
Pediatr Pulmonol. 2016; 51(11):1183-1190 Doi: 10.1002/ppul.23431
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Comment

** Singer, F; Casaulta, C; Latzin, P How to Monitor Early Cystic Fibrosis Lung Disease. By Multiple-Breath Washout, Chest Computed Tomography, or Both?
Am J Respir Crit Care Med. 2016; 193(1):7-8 Doi: 10.1164/rccm.201509-1862ED
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** Yammine, S; Singer, F; Latzin, P CFTR modulation for young children with cystic fibrosis.
Lancet Respir Med. 2016; 4(2):84-5 Doi: 10.1016/S2213-2600(16)00009-6
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2015

Full paper/article (Journal)

** Bigler, A; Yammine, S; Singer, F; Riedel, T; Latzin, P Feasibility of automated slope III and Scond analysis in children.
Pediatr Pulmonol. 2015; 50(8):805-13 Doi: 10.1002/ppul.23080
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** Fleming, L; Murray, C; Bansal, AT; Hashimoto, S; Bisgaard, H; Bush, A; Frey, U; Hedlin, G; Singer, F; van, Aalderen, WM; Vissing, NH; Zolkipli, Z; Selby, A; Fowler, S; Shaw, D; Chung, KF; Sousa, AR; Wagers, S; Corfield, J; Pandis, I; Rowe, A; Formaggio, E; Sterk, PJ; Roberts, G, , U-BIOPRED, Study, Group The burden of severe asthma in childhood and adolescence: results from the paediatric U-BIOPRED cohorts.
Eur Respir J. 2015; 46(5):1322-33 Doi: 10.1183/13993003.00780-2015
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** Schmidt, A; Yammine, S; Proietti, E; Frey, U; Latzin, P; Riedel, T; Singer, F Validation of multiple-breath washout equipment for infants and young children.
Pediatr Pulmonol. 2015; 50(6):607-14 Doi: 10.1002/ppul.23010
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** Shaw, DE; Sousa, AR; Fowler, SJ; Fleming, LJ; Roberts, G; Corfield, J; Pandis, I; Bansal, AT; Bel, EH; Auffray, C; Compton, CH; Bisgaard, H; Bucchioni, E; Caruso, M; Chanez, P; Dahlén, B; Dahlen, SE; Dyson, K; Frey, U; Geiser, T; Gerhardsson, de, Verdier, M; Gibeon, D; Guo, YK; Hashimoto, S; Hedlin, G; Jeyasingham, E; Hekking, PP; Higenbottam, T; Horváth, I; Knox, AJ; Krug, N; Erpenbeck, VJ; Larsson, LX; Lazarinis, N; Matthews, JG; Middelveld, R; Montuschi, P; Musial, J; Myles, D; Pahus, L; Sandström, T; Seibold, W; Singer, F; Strandberg, K; Vestbo, J; Vissing, N; von, Garnier, C; Adcock, IM; Wagers, S; Rowe, A; Howarth, P; Wagener, AH; Djukanovic, R; Sterk, PJ; Chung, KF, , U-BIOPRED, Study, Group Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort.
Eur Respir J. 2015; 46(5):1308-21 Doi: 10.1183/13993003.00779-2015
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** Stanojevic, S; Jensen, R; Sundaralingam, D; Salazar, JG; Yammine, S; Singer, F; Latzin, P; Amin, R; Subbarao, P; Gustafsson, P; Ratjen, F Alternative outcomes for the multiple breath washout in children with CF.
J Cyst Fibros. 2015; 14(4):490-6 Doi: 10.1016/j.jcf.2014.12.008
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** Steinmann, M; Abbas, C; Singer, F; Casaulta, C; Regamey, N; Haffner, D; Fischer, DC; Simonetti, GD Arterial stiffness is increased in asthmatic children.
Eur J Pediatr. 2015; 174(4):519-23 Doi: 10.1007/s00431-014-2423-2
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** Subbarao, P; Milla, C; Aurora, P; Davies, JC; Davis, SD; Hall, GL; Heltshe, S; Latzin, P; Lindblad, A; Pittman, JE; Robinson, PD; Rosenfeld, M; Singer, F; Starner, TD; Ratjen, F; Morgan, W Multiple-Breath Washout as a Lung Function Test in Cystic Fibrosis. A Cystic Fibrosis Foundation Workshop Report.
Ann Am Thorac Soc. 2015; 12(6):932-9 Doi: 10.1513/AnnalsATS.201501-021FR [OPEN ACCESS]
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** Summermatter, S; Singer, F; Latzin, P; Yammine, S Impact of Software Settings on Multiple-Breath Washout Outcomes.
PLoS One. 2015; 10(7):e0132250 Doi: 10.1371/journal.pone.0132250 [OPEN ACCESS]
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Short report/Letter

** Yammine, S; Lenherr, N; Nyilas, S; Singer, F; Latzin, P Using the same cut-off for sulfur hexafluoride and nitrogen multiple-breath washout may not be appropriate.
J Appl Physiol (1985). 2015; 119(12): 1510-2. Doi: 10.1152/japplphysiol.00333.2015
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Comment

** Yammine, S; Lenherr, N; Nyilas, S; Singer, F; Latzin, P Last Word on Viewpoint: Using the same cut-off for sulfur hexafluoride and nitrogen multiple-breath washout may not be appropriate.
J Appl Physiol (1985). 2015; 119(12):1515 Doi: 10.1152/japplphysiol.00764.2015
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2014

Full paper/article (Journal)

** Gonem, S; Singer, F; Corkill, S; Singapuri, A; Siddiqui, S; Gustafsson, P Validation of a photoacoustic gas analyser for the measurement of functional residual capacity using multiple-breath inert gas washout.
Respiration. 2014; 87(6):462-8 Doi: 10.1159/000357786
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** Husemann, K; Berg, N; Engel, J; Port, J; Joppek, C; Tao, Z; Singer, F; Schulz, H; Kohlhäufl, M Double tracer gas single-breath washout: reproducibility in healthy subjects and COPD.
Eur Respir J. 2014; 44(5):1210-22 Doi: 10.1183/09031936.00085713
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** Proietti, E; Riedel, T; Fuchs, O; Pramana, I; Singer, F; Schmidt, A; Kuehni, C; Latzin, P; Frey, U Can infant lung function predict respiratory morbidity during the first year of life in preterm infants?
Eur Respir J. 2014; 43(6):1642-51 Doi: 10.1183/09031936.00149213
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** Singer, F; Abbas, C; Yammine, S; Casaulta, C; Frey, U; Latzin, P Abnormal small airways function in children with mild asthma.
Chest. 2014; 145(3):492-499 Doi: 10.1378/chest.13-0784
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** Singer, F; Yammine, S; Schmidt, A; Proietti, E; Kieninger, E; Barben, J; Casaulta, C; Regamey, N; Gustafsson, P; Frey, U; Latzin, P Ventilatory response to nitrogen multiple-breath washout in infants.
Pediatr Pulmonol. 2014; 49(4):342-7 Doi: 10.1002/ppul.22841
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** Yammine, S; Singer, F; Gustafsson, P; Latzin, P Impact of different breathing protocols on multiple-breath washout outcomes in children.
J Cyst Fibros. 2014; 13(2):190-7 Doi: 10.1016/j.jcf.2013.08.010
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Comment

** Yammine, S; Bigler, A; Casaulta, C; Singer, F; Latzin, P Reasons for heterogeneous change in LCI in children with cystic fibrosis after antibiotic treatment.
Thorax. 2014; 69(2):183 Doi: 10.1136/thoraxjnl-2013-204283
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2013

Full paper/article (Journal)

** Abbas, C; Singer, F; Yammine, S; Casaulta, C; Latzin, P Treatment response of airway clearance assessed by single-breath washout in children with cystic fibrosis.
J Cyst Fibros. 2013; 12(6):567-74 Doi: 10.1016/j.jcf.2013.05.010
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** Kieninger, E; Singer, F; Tapparel, C; Alves, MP; Latzin, P; Tan, HL; Bossley, C; Casaulta, C; Bush, A; Davies, JC; Kaiser, L; Regamey, N High rhinovirus burden in lower airways of children with cystic fibrosis.
Chest. 2013; 143(3):782-790 Doi: 10.1378/chest.12-0954
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** Robinson, PD; Latzin, P; Verbanck, S; Hall, GL; Horsley, A; Gappa, M; Thamrin, C; Arets, HG; Aurora, P; Fuchs, SI; King, GG; Lum, S; Macleod, K; Paiva, M; Pillow, JJ; Ranganathan, S; Ranganathan, S; Ratjen, F; Singer, F; Sonnappa, S; Stocks, J; Subbarao, P; Thompson, BR; Gustafsson, PM Consensus statement for inert gas washout measurement using multiple- and single- breath tests.
Eur Respir J. 2013; 41(3):507-22 Doi: 10.1183/09031936.00069712
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** Singer, F; Kieninger, E; Abbas, C; Yammine, S; Fuchs, O; Proietti, E; Regamey, N; Casaulta, C; Frey, U; Latzin, P Practicability of nitrogen multiple-breath washout measurements in a pediatric cystic fibrosis outpatient setting.
Pediatr Pulmonol. 2013; 48(8):739-46 Doi: 10.1002/ppul.22651
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** Singer, F; Luchsinger, I; Inci, D; Knauer, N; Latzin, P; Wildhaber, JH; Moeller, A Exhaled nitric oxide in symptomatic children at preschool age predicts later asthma.
Allergy. 2013; 68(4):531-8 Doi: 10.1111/all.12127
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** Singer, F; Stern, G; Thamrin, C; Abbas, C; Casaulta, C; Frey, U; Latzin, P A new double-tracer gas single-breath washout to assess early cystic fibrosis lung disease.
Eur Respir J. 2013; 41(2):339-45 Doi: 10.1183/09031936.00044312
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Short report/Letter

** Borer, D; Yammine, S; Singer, F; Rösgen, T; Latzin, P; Obrist, D A Computer Model for Single-Breath Washout with Double-Tracer Gas to Help Understanding Ventilation Inhomogeneity.
Biomed Tech (Berl). 2013; 58 Suppl 1: Doi: 10.1515/bmt-2013-4327
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** Yammine, S; Singer, F; Abbas, C; Roos, M; Latzin, P Multiple-breath washout measurements can be significantly shortened in children.
Thorax. 2013; 68(6):586-7 Doi: 10.1136/thoraxjnl-2012-202345
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2012

Full paper/article (Journal)

** Fuchs, O; Latzin, P; Singer, F; Petrus, N; Proietti, E; Kieninger, E; Casaulta, C; Frey, U Comparison of online single-breath vs. online multiple-breath exhaled nitric oxide in school-age children.
Pediatr Res. 2012; 71(5):605-11 Doi: 10.1038/pr.2012.13
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** Singer, F; Houltz, B; Latzin, P; Robinson, P; Gustafsson, P A realistic validation study of a new nitrogen multiple-breath washout system.
PLoS One. 2012; 7(4):e36083 Doi: 10.1371/journal.pone.0036083 [OPEN ACCESS]
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Short report/Letter

** Buehler, T; Steinmann, M; Singer, F; Regamey, N; Casaulta, C; Schoeni, MH; Simonetti, GD Increased arterial stiffness in children with cystic fibrosis.
Eur Respir J. 2012; 39(6):1536-7 Doi: 10.1183/09031936.00212511
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2011

Full paper/article (Journal)

** Fuchs, O; Latzin, P; Thamrin, C; Stern, G; Frischknecht, P; Singer, F; Kieninger, E; Proietti, E; Riedel, T; Frey, U Normative data for lung function and exhaled nitric oxide in unsedated healthy infants.
Eur Respir J. 2011; 37(5):1208-16 Doi: 10.1183/09031936.00125510
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** Kieninger, E; Singer, F; Fuchs, O; Abbas, C; Frey, U; Regamey, N; Casaulta, C; Latzin, P Long-term course of lung clearance index between infancy and school-age in cystic fibrosis subjects.
J Cyst Fibros. 2011; 10(6):487-90 Doi: 10.1016/j.jcf.2011.07.006
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** Singer, F; Stern, G; Thamrin, C; Fuchs, O; Riedel, T; Gustafsson, P; Frey, U; Latzin, P Tidal volume single breath washout of two tracer gases--a practical and promising lung function test.
PLoS One. 2011; 6(3):e17588 Doi: 10.1371/journal.pone.0017588 [OPEN ACCESS]
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2008

Full paper/article (Journal)

** Fleischhackl, R; Roessler, B; Domanovits, H; Singer, F; Fleischhackl, S; Foitik, G; Czech, G; Mittlboeck, M; Malzer, R; Eisenburger, P; Hoerauf, K Results from Austria's nationwide public access defibrillation (ANPAD) programme collected over 2 years.
Resuscitation. 2008; 77(2):195-200 Doi: 10.1016/j.resuscitation.2007.11.019
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** Singer, F; Horak, F; Friesenbichler, W; Schneider, B; Szépfalusi, Z; Frischer, T Cysteinyl-leukotrienes in nasal lavage fluid in children with asthma.
Pediatr Allergy Immunol. 2008; 19(3):227-32 Doi: 10.1111/j.1399-3038.2007.00614.x
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2007

Full paper/article (Journal)

** Horak, F; Moeller, A; Singer, F; Straub, D; Höller, B; Helbich, TH; Schneider, B; Eichler, I; Wildhaber, JH; Hall, GL Longitudinal monitoring of pediatric cystic fibrosis lung disease using nitrite in exhaled breath condensate.
Pediatr Pulmonol. 2007; 42(12):1198-206 Doi: 10.1002/ppul.20719
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2006

Full paper/article (Journal)

** Fleischhackl, R; Singer, F; Nitsche, W; Gamperl, G; Roessler, B; Arrich, J; Fleischhackl, S; Losert, H; Sterz, F; Mittlboeck, M; Hoerauf, K Influence of electromagnetic fields on function of automated external defibrillators.
Acad Emerg Med. 2006; 13(1):1-6 Doi: 10.1197/j.aem.2005.07.036
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** Fleischhackl, R; Singer, F; Roessler, B; Arrich, J; Fleischhackl, S; Losert, H; Uray, T; Koehler, K; Sterz, F; Mittlboeck, M; Hoerauf, K Automated external defibrillators do not recommend false positive shocks under the influence of electromagnetic fields present at public locations.
Anesth Analg. 2006; 103(6):1485-8 Doi: 10.1213/01.ane.0000244477.15072.16
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