Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Lohberger Birgit |

** = Publikationen gelistet in SCI/SSCI/Pubmed

2025

Originalarbeit (Zeitschrift)

** Igrec, J; Jernej, L; Smolle, MA; Steiner, J; Scheipl, S; Lohberger, B; Leithner, A; Brcic, I Surgical and radiological outcomes of giant cell tumor of the bone: prognostic value of Campanacci grading and selective use of denosumab.
J Orthop Traumatol. 2025; 26(1): 27 Doi: 10.1186/s10195-025-00841-2 [OPEN ACCESS]
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2024

Originalarbeit (Zeitschrift)

** Astasov-Frauenhoffer, M; Marot, L; Sanchez, F; Steiner, R; Lohberger, B; Bornstein, MM; Wagner, RS; Kühl, S; Mukaddam, K Effects of nanomodified titanium surfaces considering bacterial colonization and viability of osteoblasts and fibroblasts.
J Biomed Mater Res A. 2024; Doi: 10.1002/jbm.a.37768
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** Etschmaier, V; Üçal, M; Lohberger, B; Weinberg, A; Schäfer, U Ex vivo organotypic bone slice culture reveals preferential chondrogenesis after sustained growth plate injury.
Cells Dev. 2024; 203927 Doi: 10.1016/j.cdev.2024.203927
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** Lohberger, B; Barna, S; Glänzer, D; Eck, N; Leithner, A; Georg, D DNA-PKcs Inhibition Sensitizes Human Chondrosarcoma Cells to Carbon Ion Irradiation via Cell Cycle Arrest and Telomere Capping Disruption.
Int J Mol Sci. 2024; 25(11): 6179 Doi: 10.3390/ijms25116179 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Weigl, L; Lohberger, B; Glanz, V; Glaenzer, D; Steinecker-Frohnwieser, B ELECTRICAL ACTIVATION OF MUSCLE CELLS INFLUENCES OA CHONDROCYTES UNDER MECHANICAL STIMULATION
OSTEOARTHR CARTILAGE. 2024; 32: S452-S453. [Poster]
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2023

Originalarbeit (Zeitschrift)

** Etschmaier, V; Glänzer, D; Eck, N; Schäfer, U; Leithner, A; Georg, D; Lohberger, B Proton and Carbon Ion Irradiation Changes the Process of Endochondral Ossification in an Ex Vivo Femur Organotypic Culture Model.
Cells. 2023; 12(18): 2301 Doi: 10.3390/cells12182301 [OPEN ACCESS]
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** Etschmaier, V; Üçal, M; Lohberger, B; Absenger-Novak, M; Kolb, D; Weinberg, A; Schäfer, U Disruption of Endochondral Ossification and Extracellular Matrix Maturation in an Ex Vivo Rat Femur Organotypic Slice Model Due to Growth Plate Injury.
Cells. 2023; 12(13): 1687 Doi: 10.3390/cells12131687 [OPEN ACCESS]
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** Hörlesberger, N; Zinggl, C; Smolle, MA; Leitner, L; Lohberger, B; Leithner, A; Sadoghi, P Mechanically aligned total knee arthroplasty with the extension-first technique does not equally restore neutral knee alignment in all preoperative knee phenotypes.
Knee Surg Sports Traumatol Arthrosc. 2023; 31(4):1405-1411 Doi: 10.1007/s00167-022-07147-4 [OPEN ACCESS]
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** Liebhauser, M; Hohenberger, G; Lohberger, B; Hauer, G; Deluca, A; Sadoghi, P Implant breakage after shoulder arthroplasty: a systematic review of data from worldwide arthroplasty registries and clinical trials.
BMC Musculoskelet Disord. 2023; 24(1): 804 Doi: 10.1186/s12891-023-06922-9 [OPEN ACCESS]
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** Lohberger, B; Glänzer, D; Eck, N; Stasny, K; Falkner, A; Leithner, A; Georg, D The ATR Inhibitor VE-821 Enhances the Radiosensitivity and Suppresses DNA Repair Mechanisms of Human Chondrosarcoma Cells.
Int J Mol Sci. 2023; 24(3): Doi: 10.3390/ijms24032315 [OPEN ACCESS]
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** Lohberger, B; Kaltenegger, H; Eck, N; Glänzer, D; Leithner, A; Kretschmer, N The Biological Assessment of Shikonin and β,β-dimethylacrylshikonin Using a Cellular Myxofibrosarcoma Tumor Heterogeneity Model.
Int J Mol Sci. 2023; 24(21): Doi: 10.3390/ijms242115910 [OPEN ACCESS]
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** Steinecker-Frohnwieser, B; Lohberger, B; Toegel, S; Windhager, R; Glanz, V; Kratschmann, C; Leithner, A; Weigl, L Activation of the Mechanosensitive Ion Channels Piezo1 and TRPV4 in Primary Human Healthy and Osteoarthritic Chondrocytes Exhibits Ion Channel Crosstalk and Modulates Gene Expression.
Int J Mol Sci. 2023; 24(9): Doi: 10.3390/ijms24097868 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Lohberger, B; Sadoghi, P; Leithner, A; Kretschmer, N; Steinecker-Frohnwieser, B NEXT GENERATION SEQUENCING AND SHIKONIN EFFECTS ON HUMAN PRIMARY ARTICULAR OSTEOARTHRITIS CHONDROCYTES
ANN RHEUM DIS. 2023; 82: 1196-1196. Doi: 10.1136/annrheumdis-2023-eular.3578 [Poster]
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** Lohberger, B; Steinecker-Frohnwieser, B; Glanz, V; Toegel, S; Weigl, L CHEMICALLY AND MECHANICALLY ACTIVATED PIEZO1 LEADS TO CHANGES IN THE EXPRESSION OF ECM-MODULATING FACTORS THAT DIFFER BETWEEN HEALTHY AND HUMAN OA CHONDROCYTES
ANN RHEUM DIS. 2023; 82: 459-459. Doi: 10.1136/annrheumdis-2023-eular.5964 [Poster]
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2022

Originalarbeit (Zeitschrift)

** Kerschbaum-Gruber, S; Padilla-Cabal, F; Mara, E; Lohberger, B; Georg, D; Fuchs, H An external perpendicular magnetic field does not influence survival and DNA damage after proton and carbon ion irradiation in human cancer cells.
Z Med Phys. 2022; 32(3):326-333 Doi: 10.1016/j.zemedi.2021.11.001 [OPEN ACCESS]
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** Kretschmer, N; Durchschein, C; Hufner, A; Rinner, B; Lohberger, B; Bauer, R SK119, a Novel Shikonin Derivative, Leads to Apoptosis in Melanoma Cell Lines and Exhibits Synergistic Effects with Vemurafenib and Cobimetinib
INT J MOL SCI. 2022; 23(10): 5684 Doi: 10.3390/ijms23105684 [OPEN ACCESS]
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** Lohberger, B; Barna, S; Glänzer, D; Eck, N; Kerschbaum-Gruber, S; Stasny, K; Leithner, A; Georg, D Cellular and Molecular Biological Alterations after Photon, Proton, and Carbon Ions Irradiation in Human Chondrosarcoma Cells Linked with High-Quality Physics Data.
Int J Mol Sci. 2022; 23(19): Doi: 10.3390/ijms231911464 [OPEN ACCESS]
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** Lohberger, B; Glänzer, D; Kaltenegger, H; Eck, N; Leithner, A; Bauer, R; Kretschmer, N; Steinecker-Frohnwieser, B Shikonin derivatives cause apoptosis and cell cycle arrest in human chondrosarcoma cells via death receptors and MAPK regulation.
BMC Cancer. 2022; 22(1):758 Doi: 10.1186/s12885-022-09857-x [OPEN ACCESS]
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** Lohberger, B; Kaltenegger, H; Eck, N; Glänzer, D; Sadoghi, P; Leithner, A; Bauer, R; Kretschmer, N; Steinecker-Frohnwieser, B Shikonin Derivatives Inhibit Inflammation Processes and Modulate MAPK Signaling in Human Healthy and Osteoarthritis Chondrocytes.
Int J Mol Sci. 2022; 23(6): Doi: 10.3390/ijms23063396 [OPEN ACCESS]
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** Paulitsch-Fuchs, AH; Bödendorfer, B; Wolrab, L; Eck, N; Dyer, NP; Lohberger, B Effect of Cobalt-Chromium-Molybdenum Implant Surface Modifications on Biofilm Development of S. aureus and S. epidermidis.
Front Cell Infect Microbiol. 2022; 12: 837124 Doi: 10.3389/fcimb.2022.837124 [OPEN ACCESS]
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** Schadler, P; Lohberger, B; Thauerer, B; Faschingbauer, M; Kullich, W; Stradner, MH; Leithner, A; Ritschl, V; Omara, M; Steinecker-Frohnwieser, B The Association of Blood Biomarkers and Body Mass Index in Knee Osteoarthritis: A Cross-Sectional Study.
Cartilage. 2022; 13(1): 19476035211069251 Doi: 10.1177/19476035211069251 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Lohberger, B; Kaltenegger, H; Eck, N; Glanzer, D; Leithner, A; Bauer, R; Kretschmer, N; Steinecker-Frohnwieser, B THE SUPPRESSION OF INFLAMMATORY PROCESSES AND MODULATION OF MAPK SIGNALING BY SHIKONIN DERIVATIVES IN PRIMARY OA CHONDROCYTES
ANN RHEUM DIS. 2022; 81: 1159-1159. Doi: 10.1136/annrheumdis-2022-eular.1544 [Poster]
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** Steinecker, B; Lohberger, B; Kratschmann, C; Glanz, V; Cezanne, M; Kullich, W; Toegel, S; Weigl, L PIEZO1 AND TRPV4 CROSSTALK IN HUMAN PRIMARY OA CHONDROCYTES
OSTEOARTHR CARTILAGE. 2022; 30: S170-S171. [Poster]
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2021

Originalarbeit (Zeitschrift)

** Kretschmer, N; Hufner, A; Durchschein, C; Popodi, K; Rinner, B; Lohberger, B; Bauer, R Synthesis and Pharmacological In Vitro Investigations of Novel Shikonin Derivatives with a Special Focus on Cyclopropane Bearing Derivatives.
Int J Mol Sci. 2021; 22(5): Doi: 10.3390/ijms22052774 [OPEN ACCESS]
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** Lohberger, B; Eck, N; Glaenzer, D; Kaltenegger, H; Leithner, A Surface Modifications of Titanium Aluminium Vanadium Improve Biocompatibility and Osteogenic Differentiation Potential.
Materials (Basel). 2021; 14(6): Doi: 10.3390/ma14061574 [OPEN ACCESS]
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** Lohberger, B; Glaenzer, D; Eck, N; Steinecker-Frohnwieser, B; Leithner, A; Rinner, B; Kerschbaum-Gruber, S; Georg, D Effects of a combined therapy of bortezomib and ionizing radiation on chondrosarcoma three-dimensional spheroid cultures.
Oncol Lett. 2021; 21(6): 428-428. Doi: 10.3892/ol.2021.12689 [OPEN ACCESS]
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** Lohberger, B; Glänzer, D; Eck, N; Kerschbaum-Gruber, S; Mara, E; Deycmar, S; Madl, T; Kashofer, K; Georg, P; Leithner, A; Georg, D Activation of efficient DNA repair mechanisms after photon and proton irradiation of human chondrosarcoma cells.
Sci Rep. 2021; 11(1): 24116 Doi: 10.1038/s41598-021-03529-9 [OPEN ACCESS]
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** Lohberger, B; Scheipl, S; Heitzer, E; Quehenberger, F; de, Jong, D; Szuhai, K; Liegl-Atzwanger, B; Rinner, B Higher cMET dependence of sacral compared to clival chordoma cells: contributing to a better understanding of cMET in chordoma.
Sci Rep. 2021; 11(1): 12466 Doi: 10.1038/s41598-021-92018-0 [OPEN ACCESS]
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** Paulitsch-Fuchs, AH; Wolrab, L; Eck, N; Dyer, NP; Bödendorfer, B; Lohberger, B TiAl6V4 Alloy Surface Modifications and Their Impact on Biofilm Development of S. aureus and S. epidermidis.
J Funct Biomater. 2021; 12(2): Doi: 10.3390/jfb12020036 [OPEN ACCESS]
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** Schadler, P; Lohberger, B; Stündl, N; Stradner, MH; Glänzer, D; Sadoghi, P; Leithner, A; Steinecker-Frohnwieser, B The Effect of Body Mass Index and Metformin on Matrix Gene Expression in Arthritic Primary Human Chondrocytes.
Cartilage. 2021; 13(2_suppl):1004S-1018S Doi: 10.1177/1947603520962558 [OPEN ACCESS]
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** Schadler, P; Lohberger, B; Thauerer, B; Faschingbauer, M; Kullich, W; Stradner, MH; Husic, R; Leithner, A; Steinecker-Frohnwieser, B Fatty Acid-Binding Protein 4 (FABP4) Is Associated with Cartilage Thickness in End-Stage Knee Osteoarthritis.
Cartilage. 2021; 13(2_suppl):1165S-1173S Doi: 10.1177/19476035211011520 [OPEN ACCESS]
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** Scheipl, S; Barnard, M; Lohberger, B; Zettl, R; Brcic, I; Liegl-Atzwanger, B; Rinner, B; Meindl, C; Fröhlich, E Drug combination screening as a translational approach toward an improved drug therapy for chordoma.
Cell Oncol (Dordr). 2021; 44(6):1231-1242 Doi: 10.1007/s13402-021-00632-x [OPEN ACCESS]
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** Steinecker-Frohnwieser, B; Lohberger, B; Eck, N; Mann, A; Kratschmann, C; Leithner, A; Kullich, W; Weigl, L Nuclear Magnetic Resonance Therapy Modulates the miRNA Profile in Human Primary OA Chondrocytes and Antagonizes Inflammation in Tc28/2a Cells.
Int J Mol Sci. 2021; 22(11): 5959 Doi: 10.3390/ijms22115959 [OPEN ACCESS]
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2020

Originalarbeit (Zeitschrift)

** Djalinac, N; Ljubojevic-Holzer, S; Matzer, I; Kolesnik, E; Jandl, K; Lohberger, B; Rainer, P; Heinemann, A; Sedej, S; von, Lewinski, D; Bisping, E The role of stretch, tachycardia and sodium-calcium exchanger in induction of early cardiac remodelling.
J Cell Mol Med. 2020; 24(15):8732-8743 Doi: 10.1111/jcmm.15504 [OPEN ACCESS]
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** Krukiewicz, K; Putzer, D; Stuendl, N; Lohberger, B; Awaja, F Enhanced Osteogenic Differentiation of Human Primary Mesenchymal Stem and Progenitor Cultures on Graphene Oxide/Poly(methyl methacrylate) Composite Scaffolds.
Materials (Basel). 2020; 13(13): 2991 Doi: 10.3390/ma13132991 [OPEN ACCESS]
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** Lohberger, B; Bernhart, E; Stuendl, N; Glaenzer, D; Leithner, A; Rinner, B; Bauer, R; Kretschmer, N Periplocin mediates TRAIL-induced apoptosis and cell cycle arrest in human myxofibrosarcoma cells via the ERK/p38/JNK pathway.
Phytomedicine. 2020; 76: 153262-153262. Doi: 10.1016/j.phymed.2020.153262 [OPEN ACCESS]
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** Lohberger, B; Eck, N; Glaenzer, D; Lichtenegger, H; Ploszczanski, L; Leithner, A Cobalt Chromium Molybdenum Surface Modifications Alter the Osteogenic Differentiation Potential of Human Mesenchymal Stem Cells.
Materials (Basel). 2020; 13(19): Doi: 10.3390/ma13194292 [OPEN ACCESS]
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** Lohberger, B; Stuendl, N; Glaenzer, D; Rinner, B; Donohue, N; Lichtenegger, HC; Ploszczanski, L; Leithner, A CoCrMo surface modifications affect biocompatibility, adhesion, and inflammation in human osteoblasts.
Sci Rep. 2020; 10(1): 1682-1682. Doi: 10.1038/s41598-020-58742-9 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Lohberger, B; Stuendl, N; Glaenzer, D; Leithner, A; Steinecker-Frohnwieser, B COBALD CHROMIUM MOLYBDENUM SURFACE MODIFICATIONS ALTER THE OSTEOGENIC DIFFERENTIATION POTENTIAL OF HUMAN MESENCHYMAL STEM CELLS
OSTEOPOROSIS INT. Abstracts. 2020; 31(SUPPL 1):S520-S520.-WCO-IOF-ESCEO 2020 -World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases; AUG 20-22, 2020; Virtuell. [Poster]
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2019

Originalarbeit (Zeitschrift)

** Fedel, M; Wong, TT; Speranza, G; Lohberger, B; Nogler, M; Awaja, F Hybrid graphene oxide/amorphous carbon coatings and their effect on the viability and toxicity of different cell types
SURF COAT TECH. 2019; 374: 95-102. Doi: 10.1016/j.surfcoat.2019.05.057
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** Heitzer, E; Groenewoud, A; Meditz, K; Lohberger, B; Liegl-Atzwanger, B; Prokesch, A; Kashofer, K; Behrens, D; Haybaeck, J; Kolb-Lenz, D; Koefeler, H; Riedl, S; Schaider, H; Fischer, C; Snaar-Jagalska, BE; de'Jong, D; Szuhai, K; Zweytick, D; Rinner, B Human melanoma brain metastases cell line MUG-Mel1, isolated clones and their detailed characterization.
Sci Rep. 2019; 9(1):4096-4096 Doi: 10.1038/s41598-019-40570-1 [OPEN ACCESS]
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** Leitner, L; Gruber, G; Lohberger, B; Kaltenegger, H; Leithner, A; Sadoghi, P [Clinical administration of platelet-rich plasma and growth factors to the musculoskeletal system].
Orthopade. 2019; 48(1):105-116 Doi: 10.1007/s00132-018-3643-3
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** Lohberger, B; Kaltenegger, H; Weigl, L; Mann, A; Kullich, W; Stuendl, N; Leithner, A; Steinecker-Frohnwieser, B Mechanical exposure and diacerein treatment modulates integrin-FAK-MAPKs mechanotransduction in human osteoarthritis chondrocytes.
Cell Signal. 2019; 56(2):23-30 Doi: 10.1016/j.cellsig.2018.12.010 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Lohberger, B; Weigl, L; Stuendl, N; Mann, A; Leithner, A; Kullich, W; Steinecker-Frohnwieser, B CHANGES IN THE MIRNA PROFILE AND HYPOXIC BEHAVIOUR OF HUMAN CHONDROCYTES BY THERAPEUTIC NUCLEAR MAGNETIC RESONANCE THERAPY (NMRT)
ANN RHEUM DIS. 2019; 78: 1514-1514. Doi: 10.1136/annrheumdis-2019-eular.7855 [Poster] [OPEN ACCESS]
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** Weigl, L; Lohberger, B; Kaltenegger, H; Kratschmann, C; Glanz, V; Leithner, A; Kullich, W; Steinecker-Frohnwieser, B INFLUENCE OF DIACEREIN ON THE MECHANOSENSITIVE SIGNAL-TRANSDUCTION AND PIEZO1 IN CHONDROCYTES
OSTEOPOROSIS INT. 2019; 30: S527-S528. [Poster]
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2018

Originalarbeit (Zeitschrift)

** Awaja, F; Speranza, G; Kaltenegger, H; Coraça-Huber, D; Lohberger, B Surface modification and characterization of GO/polymer thin coatings as excellent bio-active platforms for tissue regeneration.
Mater Sci Eng C Mater Biol Appl. 2018; 84: 130-139. Doi: 10.1016/j.msec.2017.11.030
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** Durchschein, C; Hufner, A; Rinner, B; Stallinger, A; Deutsch, A; Lohberger, B; Bauer, R; Kretschmer, N Synthesis of Novel Shikonin Derivatives and Pharmacological Effects of Cyclopropylacetylshikonin on Melanoma Cells.
Molecules. 2018; 23(11): Doi: 10.3390/molecules23112820 [OPEN ACCESS]
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** Jahanafrooz, Z; Stallinger, A; Anders, I; Kleinegger, F; Lohberger, B; Durchschein, C; Bauer, R; Deutsch, A; Rinner, B; Kretschmer, N Influence of silibinin and β-β-dimethylacrylshikonin on chordoma cells.
Phytomedicine. 2018; 49(11):32-40 Doi: 10.1016/j.phymed.2018.06.005
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** Kolb-Lenz, D; Fuchs, R; Lohberger, B; Heitzer, E; Meditz, K; Pernitsch, D; Pritz, E; Groselj-Strele, A; Leithner, A; Liegl-Atzwanger, B; Rinner, B Characterization of the endolysosomal system in human chordoma cell lines: is there a role of lysosomes in chemoresistance of this rare bone tumor?
Histochem Cell Biol. 2018; 150(1): 83-92. Doi: 10.1007/s00418-018-1673-x [OPEN ACCESS]
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** Kretschmer, N; Deutsch, A; Durchschein, C; Rinner, B; Stallinger, A; Higareda-Almaraz, JC; Scheideler, M; Lohberger, B; Bauer, R Comparative Gene Expression Analysis in WM164 Melanoma Cells Revealed That β-β-Dimethylacrylshikonin Leads to ROS Generation, Loss of Mitochondrial Membrane Potential, and Autophagy Induction.
Molecules. 2018; 23(11): Doi: 10.3390/molecules23112823 [OPEN ACCESS]
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** Lohberger, B; Wagner, S; Wohlmuther, J; Kaltenegger, H; Stuendl, N; Leithner, A; Rinner, B; Kunert, O; Bauer, R; Kretschmer, N Periplocin, the most anti-proliferative constituent of Periploca sepium, specifically kills liposarcoma cells by death receptor mediated apoptosis.
Phytomedicine. 2018; 51:162-170 Doi: 10.1016/j.phymed.2018.10.008
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Abstract (Zeitschrift)

** Lohberger, B; Weigl, L; Kullich, W; Leithner, A; Steinecker-Frohnwieser, B CYCLIC TENSILE STRAIN AND PHARMACOLOGICAL TREATMENT AFFECTS HUMAN CHONDROCYTES UNDER INFLAMMATORY AND NON-INFLAMMATORY CONDITIONS
OSTEOARTHR CARTILAGE. 2018; 26: S86-S87. Doi: 10.1016/j.joca.2018.02.186 [Poster]
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** Lohberger, B; Weigl, L; Mann, A; Kullich, W; Leithner, A; Steinecker-Frohnwieser, B MECHANICAL EXPOSURE AND DIACEREIN TREATMENT MODULATES INTEGRIN-FAK-MAPKS MECHANOTRANSDUCTION IN HUMAN OSTEOARTHRITIS CHONDROCYTES
ANN RHEUM DIS. 2018; 77: 1241-1242. Doi: 10.1136/annrheumdis-2018-eular.6810 [Poster]
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2017

Originalarbeit (Zeitschrift)

** Awaja, F; Cools, P; Lohberger, B; Nikiforov, AY; Speranza, G; Morent, R Functionalized, biocompatible, and impermeable nanoscale coatings for PEEK.
Mater Sci Eng C Mater Biol Appl. 2017; 76:865-870 Doi: 10.1016/j.msec.2017.03.153
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** Bernhart, E; Stuendl, N; Kaltenegger, H; Windpassinger, C; Donohue, N; Leithner, A; Lohberger, B Histone deacetylase inhibitors vorinostat and panobinostat induce G1 cell cycle arrest and apoptosis in multidrug resistant sarcoma cell lines.
Oncotarget. 2017; 8(44):77254-77267 Doi: 10.18632/oncotarget.20460 [OPEN ACCESS]
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** Bubik, S; Payer, M; Arnetzl, G; Kaltenegger, H; Leithner, A; Klampfl, A; Lohberger, B Attachment and growth of human osteoblasts on different biomaterial surfaces.
Int J Comput Dent. 2017; 20(3):229-243
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** Heitzer, E; Sunitsch, S; Gilg, MM; Lohberger, B; Rinner, B; Kashofer, K; Stündl, N; Ulz, P; Szkandera, J; Leithner, A; Liegl-Atzwanger, B Expanded molecular profiling of myxofibrosarcoma reveals potentially actionable targets.
Mod Pathol. 2017; 30(12):1698-1709 Doi: 10.1038/modpathol.2017.94 [OPEN ACCESS]
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** Lohberger, B; Stuendl, N; Leithner, A; Rinner, B; Sauer, S; Kashofer, K; Liegl-Atzwanger, B Establishment of a novel cellular model for myxofibrosarcoma heterogeneity.
Sci Rep. 2017; 7(9):44700-44700 Doi: 10.1038/srep44700 [OPEN ACCESS]
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** Plastira, I; Bernhart, E; Goeritzer, M; DeVaney, T; Reicher, H; Hammer, A; Lohberger, B; Wintersperger, A; Zucol, B; Graier, WF; Kratky, D; Malle, E; Sattler, W Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype.
J Neuroinflammation. 2017; 14(1):253-253 Doi: 10.1186/s12974-017-1024-1 [OPEN ACCESS]
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** Rinner, B; Gandolfi, G; Meditz, K; Frisch, MT; Wagner, K; Ciarrocchi, A; Torricelli, F; Koivuniemi, R; Niklander, J; Liegl-Atzwanger, B; Lohberger, B; Heitzer, E; Ghaffari-Tabrizi-Wizsy, N; Zweytick, D; Zalaudek, I MUG-Mel2, a novel highly pigmented and well characterized NRAS mutated human melanoma cell line.
Sci Rep. 2017; 7(1):2098-2098 Doi: 10.1038/s41598-017-02197-y [OPEN ACCESS]
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** Steinecker-Frohnwieser, B; Kaltenegger, H; Weigl, L; Mann, A; Kullich, W; Leithner, A; Lohberger, B Pharmacological treatment with diacerein combined with mechanical stimulation affects the expression of growth factors in human chondrocytes.
Biochem Biophys Rep. 2017; 11(10):154-160 Doi: 10.1016/j.bbrep.2017.06.006 [OPEN ACCESS]
PubMed PUBMED Central FullText FullText_MUG

 

Abstract (Zeitschrift)

** Lohberger, B; Kaltenegger, H; Leithner, A; Kullich, W; Steinecker-Frohnwieser, B THE EFFECT OF THE DMOAD DIACEREINONMAPK PHOSPHORYLATION AND THEIR DOWNSTREAM PATHWAYS IN HUMAN CHONDROCYTES
OSTEOPOROSIS INT. 2017; 28: S437-S437.-WCO-IOF-ESCEO World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases; MAR 23-26, 2017; Florence, ITALY. [Poster]
Web of Science

 

** Steinecker-Frohnwieser, B; Kaltenegger, H; Weigl, L; Mann, A; Kullich, W; Leithner, A; Lohberger, B MODERATE MECHANICAL STIMULATION MODULATES CHONDROCYTES AFFECTED BY THE TRIGGER DIACEREIN UNDER INFLAMMATORY AND NON-INFLAMMATORY CONDITIONS
OSTEOPOROSIS INT. 2017; 28: S383-S384. [Poster]
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2016

Originalarbeit (Zeitschrift)

** Gellner, V; Tomazic, PV; Lohberger, B; Meditz, K; Heitzer, E; Mokry, M; Koele, W; Leithner, A; Liegl-Atzwanger, B; Rinner, B Establishment of clival chordoma cell line MUG-CC1 and lymphoblastoid cells as a model for potential new treatment strategies.
Sci Rep. 2016; 6(7):24195-24195 Doi: 10.1038/srep24195 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Lohberger, B; Kaltenegger, H; Stuendl, N; Rinner, B; Leithner, A; Sadoghi, P Impact of cyclic mechanical stimulation on the expression of extracellular matrix proteins in human primary rotator cuff fibroblasts.
Knee Surg Sports Traumatol Arthrosc. 2016; 24(12):3884-3891 Doi: 10.1007/s00167-015-3790-6 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

** Lohberger, B; Steinecker-Frohnwieser, B; Stuendl, N; Kaltenegger, H; Leithner, A; Rinner, B The Proteasome Inhibitor Bortezomib Affects Chondrosarcoma Cells via the Mitochondria-Caspase Dependent Pathway and Enhances Death Receptor Expression and Autophagy.
PLoS One. 2016; 11(12):e0168193-e0168193 Doi: 10.1371/journal.pone.0168193 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Abstract (Zeitschrift)

** Djalinac, N; Kaltenegger, H; Lohberger, B; Thon-Gutschi, EM; Herbst, V; Sedej, S; Bisping, E Tachycardia versus stretch: differential pattern of early cardiac remodeling
EUR HEART J. .. 2016; 37: 308-308.-Congress of the European-Society-of-Cardiology (ESC); AUG 27-31, 2016; Rome, ITALY. [Poster]
Web of Science

 

** Djalinac, N; Mhatre, K; Kaltenegger, H; Lohberger, B; Thon-Gutschi, EM; Herbst, V; Sedej, S; Heinzel, F; Bisping, E Differential characteristics of hypertrophy induced by tachycardia, neurohumoral activation or stretch
WIEN KLIN WOCHENSCHR. 2016; 128: S312-S312. [Poster]
Web of Science

 

** Lohberger, B; Leithner, A; Stuendl, N; Kaltenegger, H; Kullich, W; Steinecker-Frohnwieser, B DIACEREIN RETARDS CELL GROWTH OF CHONDROSARCOMA CELLS AT THE G2/M CELL CYCLE CHECKPOINT VIA CYCLIN B1/CDK1 AND CDK2 DOWNREGULATION
OSTEOPOROSIS INT. 2016; 27: S142-S142. [Poster]
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2015

Originalarbeit (Zeitschrift)

** Fischer, C; Scheipl, S; Zopf, A; Niklas, N; Deutsch, A; Jorgensen, M; Lohberger, B; Froehlich, EV; Leithner, A; Gabriel, C; Liegl-Atzwanger, B; Rinner, B Mutation Analysis of Nine Chordoma Specimens by Targeted Next-Generation Cancer Panel Sequencing.
J Cancer. 2015; 6(10):984-989 Doi: 10.7150/jca.11371 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Froehlich, EV; Rinner, B; Deutsch, AJ; Meditz, K; Knausz, H; Troppan, K; Scheipl, S; Wibmer, C; Leithner, A; Liegl, B; Lohberger, B Examination of survivin expression in 50 chordoma specimens--A histological and in vitro study.
J Orthop Res. 2015; 33(5):771-778 Doi: 10.1002/jor.22819 [OPEN ACCESS]
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** Lohberger, B; Kretschmer, N; Bernhart, E; Rinner, B; Stuendl, N; Kaltenegger, H; Kahl, S; Bauer, R; Leithner, A 25-O-acetyl-23,24-dihydro-cucurbitacin F induces cell cycle G2/M arrest and apoptosis in human soft tissue sarcoma cells.
J Ethnopharmacol. 2015; 164(36):265-272 Doi: 10.1016/j.jep.2015.02.023
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** Lohberger, B; Leithner, A; Stuendl, N; Kaltenegger, H; Kullich, W; Steinecker-Frohnwieser, B Diacerein retards cell growth of chondrosarcoma cells at the G2/M cell cycle checkpoint via cyclin B1/CDK1 and CDK2 downregulation.
BMC Cancer. 2015; 15(3):891-891 Doi: 10.1186/s12885-015-1915-4 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Abstract (Zeitschrift)

** Kretschmer, N; Lohberger, B; Bernhart, E; Rinner, B; Stuendl, N; Kaltenegger, H; Kahl, S; Bauer, R; Leithner, A Effects of 25-O-acetyl-23,24-dihydro-cucurbitacin F on cell viability, cell cycle distribution and apoptosis induction in human soft tissue sarcoma cells
PLANTA MED. . 2015; 81(16):1482-1482.-63rd International Congress and Annual Meeting of the Society-for-Medicinal-Plant-and-Natural-Product-Research (GA); AUG 23-27, 2015; Budapest, HUNGARY. [Oral Communication]
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2014

Originalarbeit (Zeitschrift)

** Kolb, D; Pritz, E; Steinecker-Frohnwieser, B; Lohberger, B; Deutsch, A; Kroneis, T; El-Heliebi, A; Dohr, G; Meditz, K; Wagner, K; Koefeler, H; Leitinger, G; Leithner, A; Liegl-Atzwanger, B; Zweytick, D; Rinner, B Extended ultrastructural characterization of chordoma cells: the link to new therapeutic options.
PLoS One. 2014; 9(12):e114251 Doi: 10.1371/journal.pone.0114251 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Lohberger, B; Kaltenegger, H; Stuendl, N; Payer, M; Rinner, B; Leithner, A Effect of cyclic mechanical stimulation on the expression of osteogenesis genes in human intraoral mesenchymal stromal and progenitor cells.
Biomed Res Int. 2014; 2014(Pt 13):189516-189516 Doi: 10.1155/2014/189516 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Moazedi-Fuerst, FC; Hofner, M; Gruber, G; Weinhaeusel, A; Stradner, MH; Angerer, H; Peischler, D; Lohberger, B; Glehr, M; Leithner, A; Sonntagbauer, M; Graninger, WB Epigenetic differences in human cartilage between mild and severe OA.
J Orthop Res. 2014; 32(12):1636-1645 Doi: 10.1002/jor.22722 [OPEN ACCESS]
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** Payer, M; Lohberger, B; Strunk, D; Reich, KM; Acham, S; Jakse, N Effects of directly autotransplanted tibial bone marrow aspirates on bone regeneration and osseointegration of dental implants.
Clin Oral Implants Res. 2014; 25(4):468-474 Doi: 10.1111/clr.12172
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** Steinecker-Frohnwieser, B; Weigl, L; Kullich, W; Lohberger, B The disease modifying osteoarthritis drug diacerein is able to antagonize pro inflammatory state of chondrocytes under mild mechanical stimuli.
Osteoarthritis Cartilage. 2014; 22(7):1044-1052 Doi: 10.1016/j.joca.2014.05.008 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Scheipl, S; Fischer, C; Zopf, A; Deutsch, A; Jorgensen, M; Carvalho, D; Lohberger, B; Froehlich, EV; Leithner, A; Liegl, B; Rinner, B Mutation analysis of nine chordoma specimens by targeted next generation cancer panel sequencing
VIRCHOWS ARCH. 2014; 465: S326-S326. [Poster]
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** Steinecker-Frohnwieser, B; Weigl, L; Lohberger, B; Kress, HG; Kullich, W THE DISEASE MODIFYING OSTEOARTHRITIS DRUG DIACEREIN IS ABLE TO ANTAGONIZE PRO INFLAMMATORY STATE OF CHONDROCYTES UNDER MILD MECHANICAL STIMULI
ANN RHEUM DIS. 2014; 73: 823-823. Doi: 10.1136/annrheumdis-2014-eular.2900
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2013

Originalarbeit (Zeitschrift)

** Glehr, M; Breisach, M; Walzer, S; Lohberger, B; Fürst, F; Friesenbichler, J; Rinner, B; Avian, A; Windhager, R; Leithner, A The influence of resveratrol on the synovial expression of matrix metalloproteinases and receptor activator of NF-kappaB ligand in rheumatoid arthritis fibroblast-like synoviocytes.
Z Naturforsch C. 2013; 68(7-8):336-342 Doi: 10.5560/ZNC.2013.68c0336
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** Glehr, M; Fritsch-Breisach, M; Lohberger, B; Walzer, SM; Moazedi-Fuerst, F; Rinner, B; Gruber, G; Graninger, W; Leithner, A; Windhager, R Influence of resveratrol on rheumatoid fibroblast-like synoviocytes analysed with gene chip transcription.
Phytomedicine. 2013; 20(3-4):310-318 Doi: 10.1016/j.phymed.2012.09.020
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** Lohberger, B; Payer, M; Rinner, B; Kaltenegger, H; Wolf, E; Schallmoser, K; Strunk, D; Rohde, E; Berghold, A; Pekovits, K; Wildburger, A; Leithner, A; Windhager, R; Jakse, N Tri-lineage potential of intraoral tissue-derived mesenchymal stromal cells.
J Craniomaxillofac Surg. 2013; 41(2):110-118 Doi: 10.1016/j.jcms.2012.06.001
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** Lohberger, B; Rinner, B; Stuendl, N; Kaltenegger, H; Steinecker-Frohnwieser, B; Bernhart, E; Bonyadi Rad, E; Weinberg, AM; Leithner, A; Bauer, R; Kretschmer, N Sesquiterpene lactones downregulate G2/M cell cycle regulator proteins and affect the invasive potential of human soft tissue sarcoma cells.
PLoS One. 2013; 8(6):e66300-e66300 Doi: 10.1371/journal.pone.0066300 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

** Lohberger, B; Stuendl, N; Wolf, E; Liegl-Atzwanger, B; Leithner, A; Rinner, B The novel myxofibrosarcoma cell line MUG-Myx1 expresses a tumourigenic stem-like cell population with high aldehyde dehydrogenase 1 activity.
BMC Cancer. 2013; 13(1):563-563 Doi: 10.1186/1471-2407-13-563 [OPEN ACCESS]
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** Rinner, B; Weinhaeusel, A; Lohberger, B; Froehlich, EV; Pulverer, W; Fischer, C; Meditz, K; Scheipl, S; Trajanoski, S; Guelly, C; Leithner, A; Liegl, B Chordoma characterization of significant changes of the DNA methylation pattern.
PLoS One. 2013; 8(3):e56609-e56609 Doi: 10.1371/journal.pone.0056609 [OPEN ACCESS]
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** Sadoghi, P; Lohberger, B; Aigner, B; Kaltenegger, H; Friesenbichler, J; Wolf, M; Sununu, T; Leithner, A; Vavken, P Effect of platelet-rich plasma on the biologic activity of the human rotator-cuff fibroblasts: A controlled in vitro study.
J Orthop Res. 2013; 31(8):1249-1253 Doi: 10.1002/jor.22360 [OPEN ACCESS]
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** Scheipl, S; Lohberger, B; Rinner, B; Froehlich, EV; Beham, A; Quehenberger, F; Lazáry, A; Pal Varga, P; Haybaeck, J; Leithner, A; Liegl, B Histone deacetylase inhibitors as potential therapeutic approaches for chordoma: an immunohistochemical and functional analysis.
J Orthop Res. 2013; 31(12):1999-2005 Doi: 10.1002/jor.22447 [OPEN ACCESS]
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Abstract (Zeitschrift)

** Kretschmer, N; Rinner, B; Deutsch, A; Lohberger, B; Schaider, H; Bauer, R In vitro effects of dimethylacrylshikonin on melanoma cells
J DTSCH DERMATOL GES. . 2013; 11: 92-92. [Poster]
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** Scheipl, S; Lohberger, B; Froehlich, EV; Rinner, B; Beham, A; Quehenberger, F; Varga, PP; Lazary, A; Haybaeck, J; Leithner, A; Liegl, B; Histone deacetylase inhibitors as potential therapeutic approaches for chordoma: An immunohistochemical and functional analysis in MUG-chor1.
VIRCHOWS ARCHIV. 2013; 463(2):104-104.-25th European Congress of Pathology; AUG 31 - SEP 4, 2013; Lisbon. [Oral Communication]
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2012

Originalarbeit (Zeitschrift)

** Kretschmer, N; Rinner, B; Deutsch, AJ; Lohberger, B; Knausz, H; Kunert, O; Blunder, M; Boechzelt, H; Schaider, H; Bauer, R Naphthoquinones from Onosma paniculata induce cell-cycle arrest and apoptosis in melanoma Cells.
J Nat Prod. 2012; 75(5):865-869 Doi: 10.1021/np2006499 [OPEN ACCESS]
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** Kretschmer, N; Rinner, B; Stuendl, N; Kaltenegger, H; Wolf, E; Kunert, O; Boechzelt, H; Leithner, A; Bauer, R; Lohberger, B Effect of costunolide and dehydrocostus lactone on cell cycle, apoptosis, and ABC transporter expression in human soft tissue sarcoma cells.
Planta Med. 2012; 78(16):1749-1756 Doi: 10.1055/s-0032-1315385 [OPEN ACCESS]
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** Lohberger, B; Payer, M; Rinner, B; Bartmann, C; Stadelmeyer, E; Traunwieser, E; DeVaney, T; Jakse, N; Leithner, A; Windhager, R Human intraoral harvested mesenchymal stem cells: characterization, multilineage differentiation analysis, and 3-dimensional migration of natural bone mineral and tricalcium phosphate scaffolds.
J Oral Maxillofac Surg. 2012; 70(10):2309-2315 Doi: 10.1016/j.joms.2011.06.216
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** Lohberger, B; Rinner, B; Stuendl, N; Absenger, M; Liegl-Atzwanger, B; Walzer, SM; Windhager, R; Leithner, A Aldehyde dehydrogenase 1, a potential marker for cancer stem cells in human sarcoma.
PLoS One. 2012; 7(8):e43664-e43664 Doi: 10.1371/journal.pone.0043664 [OPEN ACCESS]
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** Rinner, B; Froehlich, EV; Buerger, K; Knausz, H; Lohberger, B; Scheipl, S; Fischer, C; Leithner, A; Guelly, C; Trajanoski, S; Szuhai, K; Liegl, B Establishment and detailed functional and molecular genetic characterisation of a novel sacral chordoma cell line, MUG-Chor1.
Int J Oncol. 2012; 40(2): 443-451. Doi: 10.3892/ijo.2011.1235 [OPEN ACCESS]
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2010

Originalarbeit (Zeitschrift)

** Payer, M; Lohberger, B; Stadelmeyer, E; Bartmann, C; Windhager, R; Jakse, N Behaviour of multipotent maxillary bone-derived cells on beta-tricalcium phosphate and highly porous bovine bone mineral.
Clin Oral Implants Res. 2010; 21(7):699-708 Doi: 10.1111/j.1600-0501.2009.01856.x
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2008

Originalarbeit (Zeitschrift)

** Windpassinger, C; Schoser, B; Straub, V; Hochmeister, S; Noor, A; Lohberger, B; Farra, N; Petek, E; Schwarzbraun, T; Ofner, L; Löscher, WN; Wagner, K; Lochmüller, H; Vincent, JB; Quasthoff, S An X-linked myopathy with postural muscle atrophy and generalized hypertrophy, termed XMPMA, is caused by mutations in FHL1.
Am J Hum Genet. 2008; 82(1): 88-99. Doi: 10.1016/j.ajhg.2007.09.004 [OPEN ACCESS]
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Abstract (Konferenzband)

** Quasthoff, S; Windpassinger C; Schoser B; Hochmeister S; Straub V; Lohberger B; Petek E; Schwarzbraun T; Wagner K, Löscher WN; Lochmüller H; Farra N; Ofner L; Mikhailov A; Vincent JB FHL1 Gene mutation associated myopathy: a novel class of inherited myopathies.
. 2008; 255(2): 33-33. [Oral Communication]
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2007

Originalarbeit (Zeitschrift)

** Rosker, C; Lohberger, B; Hofer, D; Steinecker, B; Quasthoff, S; Schreibmayer, W The TTX metabolite 4,9-anhydro-TTX is a highly specific blocker of the Na(v1.6) voltage-dependent sodium channel.
Am J Physiol Cell Physiol. 2007; 293(2): C783-C789. Doi: 10.1152/ajpcell.00070.2007 [OPEN ACCESS]
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2006

Originalarbeit (Zeitschrift)

** Hofer, D; Lohberger, B; Steinecker, B; Schmidt, K; Quasthoff, S; Schreibmayer, W A comparative study of the action of tolperisone on seven different voltage dependent sodium channel isoforms.
EUR J PHARMACOL. 2006; 538(1-3): 5-14. Doi: 10.1016/j.ejphar.2006.03.034
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2004

Abstract (Zeitschrift)

** Hofer, D; Lohberger, B; Steinecker-Frohnwieser, B; Schreibmayer, W A comparative study of the action of tolperison on different voltage dependent sodium channel isoforms.
BIOPHYS J 2004 86: 118A-118A.
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** Lohberger, B; Schmidt, K; Schreibmayer, W; Steinecker-Fohnwieser, B Studying the role of the cytoplasmic domain ID I-II of the human Nav1.5 on the beta adenergic regulation of sodium currents
BIOPHYS J 2004 86: 422A-422A.
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** Steinecker-Frohnwieser, B; Lohberger, B; Schreibmayer, W; Schmidt, K Functional role of the cytoplasmic loop IDI-II in beta 2-adrenergic regulation and modulation of cardiac voltage-gated sodium channel Na-v1.5
J MOL CELL CARDIOL 2004 36: 756-756.
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2002

Abstract (Zeitschrift)

** Lohberger, B; Steinecker-Frohnwieser, B; Schreibmayer, W Functional consequenses of the in-vitro PKA phosphorylation sites in the intracellular ID I-II loop of the human cardiac sodium channel alpha subunit
BIOPHYS J 2002 82: 92A-92A.
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2001

Abstract (Zeitschrift)

** Lohberger, B; Steinecker-Frohnwieser, B; Groschner, K; Schreibmayer, W Role of b2-subunit and ID I-II in the regulation of the human cardiac sodium channel a-subunit by PKA.
BIOPHYS J 2001 80: 224A-224A.
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2000

Originalarbeit (Zeitschrift)

** Lohberger, B; Groschner, K; Tritthart, H; Schreibmayer, W IK.ACh activation by arachidonic acid occurs via a G-protein-independent pathway mediated by the GIRK1 subunit.
Pflugers Arch. 2000; 441(2-3):251-256 Doi: 10.1007/s004240000405
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Abstract (Zeitschrift)

** Lohberger, B; Lorenz, C; Groschner, K; Schreibmayer, W Susceptibity of IKACh to activation by arachidonic acid derivatives is conferred by the GIRK1 subunit.
BIOPHYS J 2000 78: 464A-464A.
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