** = Publikationen gelistet in SCI/SSCI/Pubmed
** Allerkamp, HH; Bondarenko, AI; Tawfik, I; Kamali-Simsek, N; Horvat, Mercnik, M; Madreiter-Sokolowski, CT; Wadsack, C
In vitro Examination of Piezo1-TRPV4 Dynamics: Implications for Placental Endothelial Function in Normal and Preeclamptic Pregnancies.
Am J Physiol Cell Physiol. 2024;
Doi: 10.1152/ajpcell.00794.2024
Web of Science
PubMed
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** Juvan, ZN; Kindler, O; Kloimboeck, T; Hoebler, A; Vondra, S; Lackner, A; Feyaerts, D; Wadsack, C; Gaudilliere, B; Pollheimer, J; Kargl, J
NEUTROPHIL HETEROGENEITY AND FUNCTION IN EARLY PLACENTAL DEVELOPMENT: REGULATORS OF TROPHOBLAST INVASION?
J REPROD IMMUNOL. 2025; 167:
Doi: 10.1016/j.jri.2024.104354
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** George, M; Allerkamp, HH; Koshenov, Z; Oflaz, FE; Tam-Amersdorfer, C; Kolesnik, T; Rittchen, S; Lang, M; Fröhlich, E; Graier, W; Strobl, H; Wadsack, C
Liver X receptor activation mitigates oxysterol-induced dysfunction in fetoplacental endothelial cells.
Biochim Biophys Acta Mol Cell Biol Lipids. 2024; 1869(3):159466
Doi: 10.1016/j.bbalip.2024.159466
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** Horvat, Mercnik, M; Schliefsteiner, C; Sanchez-Duffhues, G; Wadsack, C
TGFβ signalling: a nexus between inflammation, placental health and preeclampsia throughout pregnancy.
Hum Reprod Update. 2024;
Doi: 10.1093/humupd/dmae007
[OPEN ACCESS]
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** Mercnik, MH; Wadsack, C; Schliefsteiner, C
Unlocking the secrets of Hofbauer cells in placental (patho-) physiology: Isolation and quality assessment in human term placenta.
Placenta. 2024;
Doi: 10.1016/j.placenta.2024.07.004
PubMed
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** Schliefsteiner, C; Wadsack, C; Allerkamp, HH
Exploring the Lifeline: Unpacking the Complexities of Placental Vascular Function in Normal and Preeclamptic Pregnancies.
Compr Physiol. 2024; 14(5): 5763-5787.
Doi: 10.1002/cphy.c230020
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** Allerkamp, HH; Jauch, SF; Klaritsch, P; Fluhr, H; Wadsack, C
A Fetal Genetic PIEZO1 Mutation Alters Placental Blood Vessel Density and Endothelial Barrier Functionality.
REPROD SCI. 2024; 31: 164A-164A.-71st Annual Meeting of the Society for Reproductive Investigation (SRI); MAR 12-16, 2024; Vancouver, CANADA.
[Poster]
Web of Science
** Erlandsson, L; Hirschmugl, B; Hansson, E; Mercnik, MH; Wadsack, C; Hansson, SR
PLACENTAL EXPOSURE TO URBAN AIR POLLUTION LEADS TO DISRUPTED PLACENTAL MICROARCHITECTURE AND HOFBAUER CELL POLARISATION TOWARDS A M1 PRO-INFLAMMATORY PHENOTYPE
PLACENTA. 2024; 154: E15-E15.-IFPA Annual Conference; SEP 2-6, 2024; Montreal, CANADA.
[Poster]
Web of Science
** Mihalic, Z; Kindler, O; Hoebler, AL; Wadsack, C; Pollheimer, J; Kargl, J
NEUTROPHIL DYNAMICS IN EARLY PLACENTAL DEVELOPMENT: REGULATORS OF TROPHOBLAST INVASION?
PLACENTA. 2024; 154: E76-E77.
[Poster]
Web of Science
** Berger, N; van, der, Wel, T; Hirschmugl, B; Baernthaler, T; Gindlhuber, J; Fawzy, N; Eichmann, T; Birner-Gruenberger, R; Zimmermann, R; van, der, Stelt, M; Wadsack, C
Inhibition of diacylglycerol lipase β modulates lipid and endocannabinoid levels in the ex vivo human placenta.
Front Endocrinol (Lausanne). 2023; 14: 1092024
Doi: 10.3389/fendo.2023.1092024
[OPEN ACCESS]
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** Forstner, D; Guettler, J; Brugger, BA; Lyssy, F; Neuper, L; Daxboeck, C; Cvirn, G; Fuchs, J; Kraeker, K; Frolova, A; Valdes, DS; Stern, C; Hirschmugl, B; Fluhr, H; Wadsack, C; Huppertz, B; Nonn, O; Herse, F; Gauster, M
CD39 abrogates platelet-derived factors induced IL-1β expression in the human placenta.
Front Cell Dev Biol. 2023; 11: 1183793
Doi: 10.3389/fcell.2023.1183793
[OPEN ACCESS]
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** Gajić, M; Schröder-Heurich, B; Horvat, Mercnik, M; Cervar-Zivkovic, M; Wadsack, C; von, Versen-Höynck, F; Mayer-Pickel, K
The Impact of Hydroxychloroquine on Primary Feto-Placental Endothelial Cells from Healthy and Early-Onset Preeclamptic Placentas.
INT J MOL SCI. 2023; 24(13):
Doi: 10.3390/ijms241310934
[OPEN ACCESS]
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** George, M; Lang, M; Gali, CC; Babalola, JA; Tam-Amersdorfer, C; Stracke, A; Strobl, H; Zimmermann, R; Panzenboeck, U; Wadsack, C
Liver X Receptor Activation Attenuates Oxysterol-Induced Inflammatory Responses in Fetoplacental Endothelial Cells.
CELLS-BASEL. 2023; 12(8): 1186
Doi: 10.3390/cells12081186
[OPEN ACCESS]
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** Lyssy, F; Guettler, J; Brugger, BA; Stern, C; Forstner, D; Nonn, O; Fischer, C; Herse, F; Wernitznig, S; Hirschmugl, B; Wadsack, C; Gauster, M
Platelet-derived factors dysregulate placental sphingosine-1-phosphate receptor 2 in human trophoblasts.
Reprod Biomed Online. 2023; 47(2):103215
Doi: 10.1016/j.rbmo.2023.04.006
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** Mercnik, MH; Schliefsteiner, C; Fluhr, H; Wadsack, C
Placental macrophages present distinct polarization pattern and effector functions depending on clinical onset of preeclampsia
FRONT IMMUNOL. 2023; 13: 1095879
Doi: 10.3389/fimmu.2022.1095879
[OPEN ACCESS]
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** Mihalic, ZN; Kloimböck, T; Cosic-Mujkanovic, N; Valadez-Cosmes, P; Maitz, K; Kindler, O; Wadsack, C; Heinemann, A; Marsche, G; Gauster, M; Pollheimer, J; Kargl, J
Myeloperoxidase enhances the migration and invasion of human choriocarcinoma JEG-3 cells.
Redox Biol. 2023; 67:102885
Doi: 10.1016/j.redox.2023.102885
[OPEN ACCESS]
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** Stadler, JT; Scharnagl, H; Wadsack, C; Marsche, G
Preeclampsia Affects Lipid Metabolism and HDL Function in Mothers and Their Offspring.
Antioxidants (Basel). 2023; 12(4):
Doi: 10.3390/antiox12040795
[OPEN ACCESS]
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** Stadler, JT; van, Poppel, MNM; Christoffersen, C; Hill, D; Wadsack, C; Simmons, D; Desoye, G; Marsche, G; Dali, Core, Investigator, Group
Gestational Hypertension and High-Density Lipoprotein Function: An Explorative Study in Overweight/Obese Women of the DALI Cohort.
Antioxidants (Basel). 2022; 12(1):
Doi: 10.3390/antiox12010068
[OPEN ACCESS]
Web of Science
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** Stadler, JT; van, Poppel, MNM; Wadsack, C; Holzer, M; Pammer, A; Simmons, D; Hill, D; Desoye, G; Marsche, G; Dali, Core, Investigator, Group
Obesity Affects Maternal and Neonatal HDL Metabolism and Function.
Antioxidants (Basel). 2023; 12(1):
Doi: 10.3390/antiox12010199
[OPEN ACCESS]
Web of Science
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** Allerkamp, HH; Bondarenko, O; Tawfik, I; Schaffer, S; Fluhr, H; Madreiter-Sokolowski, C; Wadsack, C
THE ION CHANNELS PIEZO1 AND TRPV4 IMPACT THE ENDOTHELIAL BARRIER OF PLACENTAS FROM NORMAL AND PREECLAMPTIC PREGNANCIES IN VITRO
PLACENTA. 2023; 140: E72-E72.-Annual Meeting of the International-Federation-of-Placenta-Associations (IFPA); SEP 05-08, 2023; Rotorua, NEW ZEALAND.
[Poster]
Web of Science
** George, M; Brandl, WT; Richtig, E; Richtig, G; Wadsack, C; Hirschmugl, B
INTERPLAY BETWEEN PREGNANCY ASSOCIATED MELANOMA CELLS AND PLACENTAL TISSUE
PLACENTA. 2023; 140: E76-E76.-Annual Meeting of the International-Federation-of-Placenta-Associations (IFPA); SEP 05-08, 2023; Rotorua, NEW ZEALAND.
[Poster]
Web of Science
** Hansson, S; Mercnik, MH; Hirschmugl, B; Wadsack, C; Erlandsson, L
THE IMPACT OF AIR POLLUTION PARTICLES ON PLACENTAL STRUCTURE AND FUNCTION
PLACENTA. 2023; 140: E24-E24.-Annual Meeting of the International-Federation-of-Placenta-Associations (IFPA); SEP 05-08, 2023; Rotorua, NEW ZEALAND.
[Oral Communication]
Web of Science
** Kothari, A; Hirschmugl, B; Lee, JS; Pfaller, B; Schmidthaler, K; Szépfalusi, Z; Wadsack, C; Eiwegger, T
Diaplacental omalizumab transfer and its impact on peanut-specific responses in a human ex vivo placental perfusion model
ALLERGY. 2023; 78: 18-19.-Annual European-Academy-of-Allergy-and-Clinical-Immunology Hybrid Congress (EAACI); JUL 01-03, 2022; Prague, CZECH REPUBLIC.
[Oral Communication]
Web of Science
** Mercnik, MH; Schliefsteiner, C; Fluhr, H; Sanchez-Duffhues, G; Goumans, MJ; Wadsack, C
A PARACRINE CROSSTALK BETWEEN HOFBAUER CELLS (HBCS) AND FETO-PLACENTAL ENDOTHELIAL CELLS (FPECS) CONTRIBUTES TO THE ENDOTHELIAL TO MESENCHYMAL TRANSITION (ENDOMT) IN EARLY ONSET PREECLAMPSIA (EO PE)
PLACENTA. 2023; 140: E88-E88.-Annual Meeting of the International-Federation-of-Placenta-Associations (IFPA); SEP 05-08, 2023; Rotorua, NEW ZEALAND.
[Poster]
Web of Science
** Mercnik, MH; Telebar, F; Schaffer, S; Fluhr, H; Sanchez-Duffhues, G; Goumans, MJE; Wadsack, C
ACTIVIN RECEPTOR-LIKE-KINASE-2 (ALK2)-SNAIL PATHWAY DRIVES ENDOTHELIAL TO MESENCHYMAL TRANSITION (ENDOMT) IN FETOPLACENTAL ENDOTHELIAL CELLS (FPEC) OF EARLY ONSET PREECLAMPSIA (EO-PE)
PLACENTA. 2023; 140: E77-E77.-Annual Meeting of the International-Federation-of-Placenta-Associations (IFPA); SEP 05-08, 2023; Rotorua, NEW ZEALAND.
[Poster]
Web of Science
** Schliefsteiner, C; Horvat-Mercnik, M; Kalcher, C; Wadsack, C
HUMAN PLACENTAL HOFBAUER CELLS HAVE DISTINCT FUNCTIONAL FEATURES AND OMIT RE-POLARIZATION IN VITRO
PLACENTA. 2023; 140: E52-E52.-Annual Meeting of the International-Federation-of-Placenta-Associations (IFPA); SEP 05-08, 2023; Rotorua, NEW ZEALAND.
[Poster]
Web of Science
** Schliefsteiner, C; Strahlhofer-Augsten, M; Woelkart, G; Allerkamp, H; Lang-Olip, I; Wadsack, C
FETAL-DERIVED HDL REGULATES PLACENTAL VASCULAR TONE PREFERENTIALLY VIA ENDOTHELIAL HYPERPOLARIZATION AND NOT EXCLUSIVELY BY ENOS
PLACENTA. 2023; 140: E66-E66.-Annual Meeting of the International-Federation-of-Placenta-Associations (IFPA); SEP 05-08, 2023; Rotorua, NEW ZEALAND.
[Poster]
Web of Science
** Stadler, J; Van Poppel, M; Desoye, G; Wadsack, C; Marsche, G
OBESITY AFFECTS MATERNAL AND NEONATAL HDL METABOLISM AND FUNCTION
ATHEROSCLEROSIS. 2023; 379: S60-S60.-91st Annual Meeting of the European-Atherosclerosis-Society (EAS); MAY 21-24, 2023; Mannheim, GERMANY.
[Oral Communication]
Web of Science
** Hirschmugl, B; Wadsack, C
Transplacental transfer of venlafaxine evaluated by ex vivo perfusion.
Placenta. 2022; 117:150-153
Doi: 10.1016/j.placenta.2021.12.007
Web of Science
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** Sand, KMK; Gruber, MM; Sandlie, I; Mathiesen, L; Andersen, JT; Wadsack, C
Contribution of the ex vivo placental perfusion model in understanding transplacental immunoglobulin G transfer
PLACENTA. 2022; 127: 77-87.
Doi: 10.1016/j.placenta.2022.07.019
Web of Science
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** Schneider, H; Albrecht, C; Ahmed, MS; Broekhuizen, M; Aengenheister, L; Buerki-Thurnherr, T; Danser, AHJ; Gil, S; Hansson, SR; Greupink, R; Lewis, RM; Markert, UR; Mathiesen, L; Powles-Glover, N; Wadsack, C; Brownbill, P
Ex vivo dual perfusion of an isolated human placenta cotyledon: Towards protocol standardization and improved inter-centre comparability.
Placenta. 2022; 126: 83-89.
Doi: 10.1016/j.placenta.2022.05.003
Web of Science
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** Strahlhofer-Augsten, M; Schliefsteiner, C; Cvitic, S; George, M; Lang-Olip, I; Hirschmugl, B; Marsche, G; Lang, U; Novakovic, B; Saffery, R; Desoye, G; Wadsack, C
The Distinct Role of the HDL Receptor SR-BI in Cholesterol Homeostasis of Human Placental Arterial and Venous Endothelial Cells.
Int J Mol Sci. 2022; 23(10): 5364
Doi: 10.3390/ijms23105364
[OPEN ACCESS]
Web of Science
PubMed
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** Kothari, A; Hirschmugl, B; Lee, JS; Pfaller, B; Schmidthaler, K; Szépfalusi, Z; Wadsack, C; Eiwegger, T
The impact of maternal-fetal omalizumab transfer on peanut-specific responses in an ex vivo placental perfusion model.
Allergy. 2022;
Doi: 10.1111/all.15468
[OPEN ACCESS]
Web of Science
PubMed
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** Berger, N; Allerkamp, H; Wadsack, C
Serine Hydrolases in Lipid Homeostasis of the Placenta-Targets for Placental Function?
Int J Mol Sci. 2022; 23(12): 6851
Doi: 10.3390/ijms23126851
[OPEN ACCESS]
Web of Science
PubMed
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** Berger, N; Barnthaler, T; Gindlhuber, J; Girgis, N; Van der Wel, T; Hirschmugl, B; Birner-Gruenberger, R; Van der Stelt, M; Wadsack, C
DAGL beta Activity Determines Endocannabinoid Biosynthesis and Arachidonic Acid Supply in the Human Placenta
REPROD SCI. 2022; 29(SUPPL 1): 158-159.
[Poster]
Web of Science
** Mercnik, MH; Schliefsteiner, C; Wadsack, C
Hofbauer Cells (HBCs) Effectively Combat Inflammatory Burden in Preeclampsia (PE)
REPROD SCI. 2022; 29(SUPPL 1): 99-100.
[Poster]
Web of Science
** Atallah, R; Gindlhuber, J; Platzer, W; Bärnthaler, T; Tatzl, E; Toller, W; Strutz, J; Rittchen, S; Luschnig, P; Birner-Gruenberger, R; Wadsack, C; Heinemann, A
SUCNR1 Is Expressed in Human Placenta and Mediates Angiogenesis: Significance in Gestational Diabetes.
Int J Mol Sci. 2021; 22(21):
Doi: 10.3390/ijms222112048
[OPEN ACCESS]
Web of Science
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** Baković, P; Kesić, M; Perić, M; Bečeheli, I; Horvatiček, M; George, M; Čičin-Šain, L; Desoye, G; Wadsack, C; Panzenboeck, U; Štefulj, J
Differential Serotonin Uptake Mechanisms at the Human Maternal-Fetal Interface.
INT J MOL SCI. 2021; 22(15):
Doi: 10.3390/ijms22157807
[OPEN ACCESS]
Web of Science
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** Del, Gaudio, I; Rubinelli, L; Sasset, L; Wadsack, C; Hla, T; Di, Lorenzo, A
Endothelial Spns2 and ApoM Regulation of Vascular Tone and Hypertension Via Sphingosine-1-Phosphate.
J Am Heart Assoc. 2021; 10(14): e021261
Doi: 10.1161/JAHA.121.021261
[OPEN ACCESS]
Web of Science
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** Hirschmugl, B; Perazzolo, S; Sengers, BG; Lewis, RM; Gruber, M; Desoye, G; Wadsack, C
Placental mobilization of free fatty acids contributes to altered materno-fetal transfer in obesity.
Int J Obes (Lond). 2021; 45(5): 1114-1123.
Doi: 10.1038/s41366-021-00781-x
[OPEN ACCESS]
Web of Science
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** Nonn, O; Fischer, C; Geisberger, S; El-Heliebi, A; Kroneis, T; Forstner, D; Desoye, G; Staff, AC; Sugulle, M; Dechend, R; Pecks, U; Kollmann, M; Stern, C; Cartwright, JE; Whitley, GS; Thilaganathan, B; Wadsack, C; Huppertz, B; Herse, F; Gauster, M
Maternal Angiotensin Increases Placental Leptin in Early Gestation via an Alternative Renin-Angiotensin System Pathway: Suggesting a Link to Preeclampsia.
Hypertension. 2021; 77(5):1723-1736
Doi: 10.1161/HYPERTENSIONAHA.120.16425
[OPEN ACCESS]
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** Schilcher, I; Stadler, JT; Lechleitner, M; Hrzenjak, A; Berghold, A; Pregartner, G; Lhomme, M; Holzer, M; Korbelius, M; Reichmann, F; Springer, A; Wadsack, C; Madl, T; Kratky, D; Kontush, A; Marsche, G; Frank, S
Endothelial Lipase Modulates Paraoxonase 1 Content and Arylesterase Activity of HDL.
Int J Mol Sci. 2021; 22(2):
Doi: 10.3390/ijms22020719
[OPEN ACCESS]
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** Schrom, S; Hebesberger, T; Wallner, SA; Anders, I; Richtig, E; Brandl, W; Hirschmugl, B; Garofalo, M; Bernecker, C; Schlenke, P; Kashofer, K; Wadsack, C; Aigelsreiter, A; Heitzer, E; Riedl, S; Zweytick, D; Kretschmer, N; Richtig, G; Rinner, B
MUG Mel3 Cell Lines Reflect Heterogeneity in Melanoma and Represent a Robust Model for Melanoma in Pregnancy.
Int J Mol Sci. 2021; 22(21):
Doi: 10.3390/ijms222111318
[OPEN ACCESS]
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** Uhl, O; Lewis, RM; Hirschmugl, B; Crozier, S; Inskip, H; Gazquez, A; Harvey, NC; Cooper, C; Desoye, G; Koletzko, B; Wadsack, C; Demmelmair, H; Godfrey, KM
Placental polar lipid composition is associated with placental gene expression and neonatal body composition.
Biochim Biophys Acta Mol Cell Biol Lipids. 2021; 1866(9): 158971
Doi: 10.1016/j.bbalip.2021.158971
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** Sconocchia, T; Del, Gaudio, I; Meshcheryakova, A; Mechtcheriakova, D; Wadsack, C; Strobl, H
Induction of the sphingosine-1-phosphate signaling pathway by TGF-β1 during Langerhans-type dendritic cell differentiation.
Eur J Immunol. 2021; 51(7): 1854-1856.
Doi: 10.1002/eji.202049013
[OPEN ACCESS]
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** Aengenheister, L; Favaro, RR; Morales-Prieto, DM; Furer, LA; Gruber, M; Wadsack, C; Markert, UR; Buerki-Thurnherr, T
Research on nanoparticles in human perfused placenta: State of the art and perspectives.
Placenta. 2021; 104:199-207
Doi: 10.1016/j.placenta.2020.12.014
[OPEN ACCESS]
Web of Science
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** Stadler, JT; Wadsack, C; Marsche, G
Fetal High-Density Lipoproteins: Current Knowledge on Particle Metabolism, Composition and Function in Health and Disease.
Biomedicines. 2021; 9(4):
Doi: 10.3390/biomedicines9040349
[OPEN ACCESS]
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** Berger, N; Barnthaler, T; Gindlhuber, J; Girgis, N; Hirschmugl, B; van der Wel, T; Zimmermann, R; Birner-Gruenberger, R; van der Stelt, M; Wadsack, C;
PLACENTAL DAGL beta REGULATES 2-ARACHIDONOYLGLYCEROL (2-AG) LEVELS AND IS INVOLVED IN PREGNANCY INDUCED INFLAMMATION.
PLACENTA. 2021; 112: E41-E42.
[Onlinepräsentation]
Web of Science
** Berger, N; Barnthaler, T; Gindlhuber, J; Girgis, N; van der Wel, T; Hirschmugl, B; Birner-Gruenberger, R; van der Stelt, M; Zimmermann, R; Wadsack, C;
Placental DAGLbeta Regulates 2-arachidonoylglycerol Levels and Is Involved in Pregnancy Induced Inflammation.
REPROD SCI. 2021; 28(SUPPL 1):279A-280A.
[Onlinepräsentation]
Web of Science
** Gajic, M; Wadsack, C; Cervar-Zivkovic, M; Mayer-Pickel, K
Hydroxychloroquine Effect on Healthy and Activated Fetoplacental Endothelial Cells In Vitro.
REPROD SCI. 2021; 28(SUPPL 1):287A-287A.
[Onlinepräsentation]
Web of Science
** Gajic, M; Wadsack, C; Zivkovic, MC; Pickel, KM
HYDROXYCHLOROQUINE: EFFECT ON FETOPLACENTAL ENDOTHELIAL ACTIVATION IN VITRO
PLACENTA. Abstracts. 2021; 112: E54-E55.
[Poster]
Web of Science
** Geroge, M; Lang, M; Tam-Amersdorfer, C; Joshua, B; Wadsack, C
LIVER-X RECEPTOR ACTIVATION ATTENUATES OXYSTEROL INDUCED INFLAMMATORY RESPONSE IN HUMAN FETO-PLACENTAL ENDOTHELIAL CELLS IN GESTATIONAL DIABETES MELLITUS
PLACENTA. Abstracts. 2021; 112: E37-E37.
[Poster]
Web of Science
** Hirschmugl, B; Wachutka, J; Meitz, S; Tamussino, K; Wadsack, C
CANNABINOID RECEPTOR EXPRESSION IN THE PLACENTA AND THEIR POTENTIAL ROLE IN ENERGY HOMEOSTASIS SIGNALLING
PLACENTA. Abstracts. 2021; 112: E73-E73.
[Poster]
Web of Science
** Kuentzel, KB; Korbelius, M; Bradic, I; Vujic, N; Gauster, M; Wadsack, C; Kratky, D
HOW DOES THE LOSS OF INTRACELLULAR LIPASES AFFECT MOUSE PLACENTA AND FETUS?
PLACENTA. 2021; 112: E73-E73.-IFPA 2021; AUG 30 - SEP 2, 2021; Amsterdam, Netherlands.
[Onlinepräsentation]
Web of Science
** Mercnik, MH; Schliefsteiner, C; Wadsack, C
SIGNAL TRANSDUCTION OF TRANSFORMING GROWTH FACTOR BETA (TGF-beta)/SMAD3 PATHWAY MODULATES THE FUNCTIONALITY OF HOFBAUER CELLS (HBC) IN PREECLAMPSIA
PLACENTA. 2021; 112: E84-E84.
[Poster]
Web of Science
** Mercnik, MH; Schliefsteiner, C; Wadsack, C
Impact of Preeclampsia on Polarization and Functionality of Hofbauer Cells.
REPROD SCI. 2021; 28(SUPPL 1):74A-74A.
[Poster]
Web of Science
** Mihalic, ZN; Raftopoulou, SN; Santiso Sanchez, A; Maitz, KS; Kindler, O; Valadez-Cosmes, P; Heinemann, A; Wadsack, C; Kargl, J
Immune cell composition at the feto-maternal interface in health and disease
J IMMUNOL. 2021; 206: -IMMUNOLOGY2021; MAY 10-15, 2021; USA.
[Poster]
Web of Science
** Nonn, O; Fischer, C; Geisberger, S; El-Heliebi, A; Kroneis, T; Forstner, D; Desoye, G; Staff, AC; Sugulle, M; Dechend, R; Pecks, U; Kollmann, M; Stern, C; Cartwright, JE; Whitley, GS; Thilaganathan, B; Wadsack, C; Huppertz, B; Herse, F; Gauster, M
MATERNAL ANGIOTENSIN INCREASES PLACENTAL LEPTIN IN EARLY GESTATION VIA AN ALTERNATIVE RAS-PATHWAY - SUGGESTING A LINK TO PRE-ECLAMPSIA
PLACENTA. 2021; 112: E25-E25.-IFPA 2021; AUG 30 - SEP 2, 2021; Amsterdam, Netherlands.
[Onlinepräsentation]
Web of Science
** Cantalupo, A; Sasset, L; Gargiulo, A; Rubinelli, L; Del Gaudio, I; Benvenuto, D; Wadsack, C; Jiang, XC; Bucci, MR; Di Lorenzo, A
Endothelial Sphingolipid De Novo Synthesis Controls Blood Pressure by Regulating Signal Transduction and NO via Ceramide.
Hypertension. 2020; 75(5):1279-1288
Doi: 10.1161/HYPERTENSIONAHA.119.14507
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** Cvitic, S; Strutz, J; Appel, HM; Weiß, E; Brandl, WT; Thüringer, A; Bernhart, EM; Lassance, L; Wadsack, C; Schliefsteiner, C; Sreckovic, I; Kashofer, K; Hiden, U
Sexual dimorphism of miRNA signatures in feto-placental endothelial cells is associated with altered barrier function and actin organization.
Clin Sci (Lond). 2020; 134(1): 39-51.
Doi: 10.1042/CS20190379
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** Del Gaudio, I; Sasset, L; Lorenzo, AD; Wadsack, C
Sphingolipid Signature of Human Feto-Placental Vasculature in Preeclampsia.
Int J Mol Sci. 2020; 21(3):
Doi: 10.3390/ijms21031019
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** Del Gaudio, I; Sreckovic, I; Zardoya-Laguardia, P; Bernhart, E; Christoffersen, C; Frank, S; Marsche, G; Illanes, SE; Wadsack, C
Circulating cord blood HDL-S1P complex preserves the integrity of the feto-placental vasculature.
Biochim Biophys Acta Mol Cell Biol Lipids. 2020; 1865(4):158632-158632
Doi: 10.1016/j.bbalip.2020.158632
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** Gaudio, ID; Hendrix, S; Christoffersen, C; Wadsack, C
Neonatal HDL Counteracts Placental Vascular Inflammation via S1P-S1PR1 Axis.
Int J Mol Sci. 2020; 21(3):
Doi: 10.3390/ijms21030789
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** Gruber, MM; Hirschmugl, B; Berger, N; Holter, M; Radulović, S; Leitinger, G; Liesinger, L; Berghold, A; Roblegg, E; Birner-Gruenberger, R; Bjelic-Radisic, V; Wadsack, C
Plasma proteins facilitates placental transfer of polystyrene particles.
J Nanobiotechnology. 2020; 18(1): 128-128.
Doi: 10.1186/s12951-020-00676-5
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** Schliefsteiner, C; Ibesich, S; Wadsack, C
Placental Hofbauer Cell Polarization Resists Inflammatory Cues In Vitro.
Int J Mol Sci. 2020; 21(3):
Doi: 10.3390/ijms21030736
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** Tupova, L; Hirschmugl, B; Sucha, S; Pilarova, V; Székely, V; Bakos, É; Novakova, L; Özvegy-Laczka, C; Wadsack, C; Ceckova, M
Interplay of drug transporters P-glycoprotein (MDR1), MRP1, OATP1A2 and OATP1B3 in passage of maraviroc across human placenta.
Biomed Pharmacother. 2020; 129(11):110506-110506
Doi: 10.1016/j.biopha.2020.110506
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** George, M; Gali, CC; Tam-Amersdorfer, C; Stracke, A; Strutz, J; Wadsack, C; Panzenboeck, U; Zimmermann, R; Leopold, B
Nuclear receptors regulating inflammatory mediators in fetoplacental endothelial cells in gestational diabetes.
DIABETOLOGIA. 2020; 63(SUPPL 1):S206-S206.-56th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD); SEP 21-25, 2020; ELECTR NETWORK.
[Poster]
Web of Science
** Bhat, VK; Bernhart, E; Plastira, I; Fan, K; Ghaffari-Tabrizi-Wizsy, N; Wadsack, C; Rechberger, G; Eichmann, T; Asslaber, M; Spassova, I; Verhaegen, ME; Malle, E; Becker, JC; Sattler, W
Pharmacological Inhibition of Serine Palmitoyl Transferase and Sphingosine Kinase-1/-2 Inhibits Merkel Cell Carcinoma Cell Proliferation.
J Invest Dermatol. 2019; 139(4):807-817
Doi: 10.1016/j.jid.2018.10.024
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** Hirschmugl, B; Brandl, W; Csapo, B; van Poppel, M; Köfeler, H; Desoye, G; Wadsack, C; Jantscher-Krenn, E
Evidence of Human Milk Oligosaccharides in Cord Blood and Maternal-to-Fetal Transport across the Placenta.
Nutrients. 2019; 11(11): 2640
Doi: 10.3390/nu11112640
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** Kiskova, T; Mytsko, Y; Schepelmann, M; Helmer, H; Fuchs, R; Miedl, H; Wadsack, C; Ellinger, I
Expression of the neonatal Fc-receptor in placental-fetal endothelium and in cells of the placental immune system.
PLACENTA. 2019; 78(4): 36-43.
Doi: 10.1016/j.placenta.2019.02.012
Web of Science
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** Schilcher, I; Ledinski, G; Radulović, S; Hallström, S; Eichmann, T; Madl, T; Zhang, F; Leitinger, G; Kolb-Lenz, D; Darnhofer, B; Birner-Gruenberger, R; Wadsack, C; Kratky, D; Marsche, G; Frank, S; Cvirn, G
Endothelial lipase increases antioxidative capacity of high-density lipoprotein.
Biochim Biophys Acta Mol Cell Biol Lipids. 2019; 1864(10):1363-1374
Doi: 10.1016/j.bbalip.2019.06.011
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** Trieb, M; Wolf, P; Knuplez, E; Weger, W; Schuster, C; Peinhaupt, M; Holzer, M; Trakaki, A; Eichmann, T; Lass, A; Wadsack, C; Schuligoi, R; Heinemann, A; Marsche, G
Abnormal composition and function of high-density lipoproteins in atopic dermatitis patients.
Allergy. 2019; 74(2):398-402
Doi: 10.1111/all.13620
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** Del Gaudio, I; Hendrix, S; Lang, U; Wadsack, C
SPHINGOSINE-1-PHOSPHATE METABOLISM AND SIGNALING ATTENUATES VASCULAR DYSFUNCTION AT THE FETO-PLACENTAL ENDOTHELIUM
PLACENTA. 2019; 83: E50-E50.-Meeting of the International-Federation-of-Placenta-Associations (IFPA); SEP 21-24, 2018; Tokyo, JAPAN.
Doi: 10.1016/j.placenta.2019.06.162
[Oral Communication]
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** Hirschmugl, B; Fawzy, N; Grill, M; Schicho, R; Lang, U; Zimmermann, R; Wadsack, C
MONOACYLGLYCEROL LIPASE MOBILISES INTRACELLULAR LIPID STORES IN THE HUMAN TERM PLACENTA
PLACENTA. 2019; 83: E60-E60.-Meeting of the International-Federation-of-Placenta-Associations (IFPA); SEP 21-24, 2018; Tokyo, JAPAN.
Doi: 10.1016/j.placenta.2019.06.197
[Poster]
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** Wadsack, C
Doctoral Program: Inflammatory Disorders in Pregnancy Medical University of researches Pregnancy Complications
PADIATR PADOL. 2019; 54(2): 52-52.
Web of Science
** Contreras-Duarte, S; Chen, P; Andía, M; Uribe, S; Irarrázaval, P; Kopp, S; Kern, S; Marsche, G; Busso, D; Wadsack, C; Rigotti, A
Attenuation of atherogenic apo B-48-dependent hyperlipidemia and high density lipoprotein remodeling induced by vitamin C and E combination and their beneficial effect on lethal ischemic heart disease in mice.
Biol Res. 2018; 51(1): 34-34.
Doi: 10.1186/s40659-018-0183-6
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** Hirschmugl, B; Crozier, S; Matthews, N; Kitzinger, E; Klymiuk, I; Inskip, HM; Harvey, NC; Cooper, C; Sibley, CP; Glazier, J; Wadsack, C; Godfrey, KM; Desoye, G; Lewis, RM
Relation of placental alkaline phosphatase expression in human term placenta with maternal and offspring fat mass.
Int J Obes (Lond). 2018;
Doi: 10.1038/s41366-018-0136-8
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** Lewis, RM; Wadsack, C; Desoye, G
Placental fatty acid transfer.
Curr Opin Clin Nutr Metab Care. 2018; 21(2):78-82
Doi: 10.1097/MCO.0000000000000443
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** Stirm, L; Kovárová, M; Perschbacher, S; Michlmaier, R; Fritsche, L; Siegel-Axel, D; Schleicher, E; Peter, A; Pauluschke-Fröhlich, J; Brucker, S; Abele, H; Wallwiener, D; Preissl, H; Wadsack, C; Häring, HU; Fritsche, A; Ensenauer, R; Desoye, G; Staiger, H
BMI-independent effects of gestational diabetes on human placenta.
J Clin Endocrinol Metab. 2018;
Doi: 10.1210/jc.2018-00397
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** Sun, Y; Kopp, S; Strutz, J; Gali, CC; Zandl-Lang, M; Fanaee-Danesh, E; Kirsch, A; Cvitic, S; Frank, S; Saffery, R; Björkhem, I; Desoye, G; Wadsack, C; Panzenboeck, U
Gestational diabetes mellitus modulates cholesterol homeostasis in human fetoplacental endothelium.
Biochim Biophys Acta. 2018; 1863(9):968-979
Doi: 10.1016/j.bbalip.2018.05.005
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** Zardoya-Laguardia, P; Blaschitz, A; Hirschmugl, B; Lang, I; Herzog, SA; Nikitina, L; Gauster, M; Häusler, M; Cervar-Zivkovic, M; Karpf, E; Maghzal, GJ; Stanley, CP; Stocker, R; Wadsack, C; Frank, S; Sedlmayr, P
Endothelial indoleamine 2,3-dioxygenase-1 regulates the placental vascular tone and is deficient in intrauterine growth restriction and pre-eclampsia.
Sci Rep. 2018; 8(1): 5488-5488.
Doi: 10.1038/s41598-018-23896-0
[OPEN ACCESS]
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** Contreras-Duarte, S; Santander, N; Birner-Gruenberger, R; Wadsack, C; Rigotti, A; Busso, D
High density lipoprotein cholesterol and proteome in SR-B1 KO mice: lost in precipitation.
J Transl Med. 2018; 16(1): 309-309.
Doi: 10.1186/s12967-018-1683-4
[OPEN ACCESS]
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** Gruber, M; Lang, U; Wadsack, C
EFFECTS OF HUMAN SERUM ALBUMIN COMPARED TO PLASMA PROTEINS ON NANOPARTICLE TRANSPORT AT THE PLACENTAL BARRIER
PLACENTA. 2018; 69: E86-E86.-Meeting of the International-Federation-of-Placenta-Associations (IFPA); SEP 21-24, 2018; Tokyo, JAPAN.
[Poster]
Web of Science
** Hirschmugl, B; Desoye, G; Catalano, P; Klymiuk, I; Scharnagl, H; Payr, S; Kitzinger, E; Schliefsteiner, C; Lang, U; Wadsack, C; Hauguel-de Mouzon, S
Maternal obesity modulates intracellular lipid turnover in the human term placenta.
Int J Obes (Lond). 2017; 41(2):317-323
Doi: 10.1038/ijo.2016.188
[OPEN ACCESS]
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** Perazzolo, S; Hirschmugl, B; Wadsack, C; Desoye, G; Lewis, RM; Sengers, BG
The influence of placental metabolism on fatty acid transfer to the fetus.
J Lipid Res. 2017; 58(2):443-454
Doi: 10.1194/jlr.P072355
[OPEN ACCESS]
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** Schliefsteiner, C; Hirschmugl, B; Kopp, S; Curcic, S; Bernhart, EM; Marsche, G; Lang, U; Desoye, G; Wadsack, C
Maternal Gestational Diabetes Mellitus increases placental and foetal lipoprotein-associated Phospholipase A2 which might exert protective functions against oxidative stress.
Sci Rep. 2017; 7(1):12628-12628
Doi: 10.1038/s41598-017-13051-6
[OPEN ACCESS]
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** Schliefsteiner, C; Peinhaupt, M; Kopp, S; Lögl, J; Lang-Olip, I; Hiden, U; Heinemann, A; Desoye, G; Wadsack, C
Human Placental Hofbauer Cells Maintain an Anti-inflammatory M2 Phenotype despite the Presence of Gestational Diabetes Mellitus.
Front Immunol. 2017; 8(5):888-888
Doi: 10.3389/fimmu.2017.00888
[OPEN ACCESS]
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** Gruber, M; Birner-Grunberger, R; Wadsack, C
ALTERED KINETICS OF NANOPARTICLES IN THE PRESENCE OF PLASMA PROTEINS AT THE HUMAN PLACENTAL BARRIER. AN EX-VIVO PLACENTAL PERFUSION AND PROTEOMICS APPROACH
PLACENTA. 2017; 57: 294-295.-Meeting of the International-Federation-of-Placenta-Associations (IFPA); AUG 30-SEP 02, 2017; Manchester, ENGLAND.
Doi: 10.1016/j.placenta.2017.07.224
[Poster]
Web of Science
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** Hirschmugl, B; Gruber, M; Lang, U; Desoye, G; Wadsack, C
PLACENTAL TRANSFER OF LONG-CHAIN POLYUNSATURATED FATTY ACIDS IS ELEVATED IN OBESE PREGNANCIES
PLACENTA. 2017; 57: 293-293.-Meeting of the International-Federation-of-Placenta-Associations (IFPA); AUG 30-SEP 02, 2017; Manchester, ENGLAND.
Doi: 10.1016/j.placenta.2017.07.220
[Poster]
Web of Science
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** Kumble, VB; Bernhart, E; Fan, K; Wadsack, C; Rechberger, G; Becker, J; Sattler, W
Interference with sphingosine 1-phosphate synthesis affects Merkel cell carcinoma proliferation in vitro
J INVEST DERMATOL. 2017; 137(10):S296-S296.-47th Annual Meeting of the European-Society-for-Dermatological-Research (ESDR); SEP 27-30, 2017; Salzburg, AUSTRIA.
[Poster]
Web of Science
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** Sun, Y; Kopp, S; Gali, CC; Zandl, M; Fanaee-Danesh, E; Bjorkhem, I; Desoye, G; Wadsack, C; Panzenboeck, U
Gestational diabetes modulates cholesterol homeostasis in human fetoplacental endothelium
DIABETOLOGIA. 2017; 60: S430-S430.-53rd Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD); SEP 11-15, 2017; Lisbon, PORTUGAL.
[Poster]
Web of Science
** Sun, YD; Kopp, S; Gali, CC; Zandl, M; Fanaee-Dane, E; Bjorkhem, I; Desoye, G; Wadsack, C; Panzenboeck, U
GESTATIONAL DIABETES MELLITUS MODULATES CHOLESTEROL METABOLISM IN HUMAN FETOPLACENTAL ENDOTHELIAL CELLS
ATHEROSCLEROSIS. 2017; 263: E74-E75.-85th Congress of the European-Atherosclerosis-Society (EAS); APR 23-26, 2017; Prague, CZECH REPUBLIC.
Doi: 10.1016/j.atherosclerosis.2017.06.247
[Oral Communication]
Web of Science
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** Zardoya-Laguardia, P; Blaschitz, A; Hirschmugl, B; Lang, I; Herzog, S; Nikitina, L; Gauster, M; Hausler, M; Cervar-Zivkovic, M; Karpf, E; Maghzal, G; Stanley, C; Stocker, R; Wadsack, C; Frank, S; Sedlmayr, P
A NOVEL TRYPTOPHAN-BASED MECHANISM REGULATING THE PLACENTAL VASCULAR TONE POTENTIAL CONTRIBUTION TO INTRAUTERINE GROWTH RESTRICTION AND PREECLAMPSIA
PLACENTA. 2017; 57: 270-270.-Meeting of the International-Federation-of-Placenta-Associations (IFPA); AUG 30-SEP 02, 2017; Manchester, ENGLAND.
Doi: 10.1016/j.placenta.2017.07.154
[Oral Communication]
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** Eder, M; Csapo, B; Wadsack, C; Haas, J; Catalano, PM; Desoye, G; van Poppel, MN
Sex differences in the association of cord blood insulin with subcutaneous adipose tissue in neonates.
Int J Obes (Lond). 2016; 40(3):538-542
Doi: 10.1038/ijo.2015.185
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** Loegl, J; Hiden, U; Nussbaumer, E; Schliefsteiner, C; Cvitic, S; Lang, I; Wadsack, C; Huppertz, B; Desoye, G
Hofbauer cells of M2a, M2b and M2c polarization may regulate feto-placental angiogenesis.
Reproduction. 2016; 152(5):447-455
Doi: 10.1530/REP-16-0159
[OPEN ACCESS]
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** Besenboeck, C; Cvitic, S; Lang, U; Desoye, G; Wadsack, C
Going into labor and beyond: phospholipase A2 in pregnancy.
Reproduction. 2016; 151(6):R91-R102
Doi: 10.1530/REP-15-0519
[OPEN ACCESS]
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** Bhat Kumble, V; Bernhart, E; Plastira, I; Kogelnik, N; Goritzer, M; Fan, K; Wadsack, C; Rechberger, G; Becker, J; Sattler, W
Merkel cell carcinoma proliferation is regulated by sphingosine-1-phosphate-mediated pathways in vitro.
J INVEST DERMATOL. 2016; 136(9):S243-S243.-Annual Meeting of the European-Society-for-Dermatological-Research (ESDR); SEP 07-10, 2016; Munich, GERMANY.
[Poster]
Web of Science
** Radisic, VB; Gruber, MM; Hirschmugl, B; Wadsack, C
Transfer of Trastuzumab (R) across the human placenta barrier
CANCER RES. 2016; 76: -38th Annual CTRC-AACR San Antonio Breast Cancer Symposium; DEC 08-12, 2015; San Antonio, TX.
Doi: 10.1158/1538-7445.SABCS15-P4-08-05
[Poster]
Web of Science
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** Wadsack, C
LpPLA2 IN GESTATIONAL DIABETES MELLITUS - A PROTECTIVE SYSTEM FOR PLACENTA AND FETUS?
ATHEROSCLEROSIS. 2016; 252: E145-E145.-Congress of the European-Atherosclerosis-Society (EAS); MAY 29-JUN 01, 2016; Innsbruck, AUSTRIA.
Doi: 10.1016/j.atherosclerosis.2016.07.716
[Poster]
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** Albrecht, C; Caniggia, I; Clifton, V; Göhner, C; Harris, L; Hemmings, D; Jawerbaum, A; Johnstone, E; Jones, H; Keelan, J; Lewis, R; Mitchell, M; Murthi, P; Powell, T; Saffery, R; Smith, R; Vaillancourt, C; Wadsack, C; Salomon, C
IFPA meeting 2015 workshop report III: nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid.
Placenta. 2016; 48 Suppl 1(2):S12-S16
Doi: 10.1016/j.placenta.2016.01.003
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** Bernhart, E; Damm, S; Wintersperger, A; Nusshold, C; Brunner, AM; Plastira, I; Rechberger, G; Reicher, H; Wadsack, C; Zimmer, A; Malle, E; Sattler, W
Interference with distinct steps of sphingolipid synthesis and signaling attenuates proliferation of U87MG glioma cells.
Biochem Pharmacol. 2015; 96(2): 119-130.
Doi: 10.1016/j.bcp.2015.05.007
[OPEN ACCESS]
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** Besenbock, C; Bilic, J; Hirschmugl, B; Desoye, G; Lang, U; Wadsack, C
Neonatal LpPLA2 and Placental SIRT1 Is Regulated by Maternal Hyperglycemia
DIABETES. . 2015; 64: A175-A175.-75th Scientific Sessions of the American-Diabetes-Association; JUN 05-09, 2015; Boston, MA.
[Oral Communication]
Web of Science
** Desoye, G; Lang, I; Wadsack, C; Scholler, M; Panzenboeck, U; Gauster, M; Lassance, L; Tokic, S; Loegl, J; Huppertz, B; Nussbaumer, E; Hiden, U
FETO-PLACENTAL ENDOTHELIUM IN PREGNANCY DISEASE
PLACENTA. 2015; 36(4): 471-471.
Doi: 10.1016/j.placenta.2015.01.385
[Oral Communication]
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** Hiden, U; Sommer, YE; Wohlfahrter, E; Lang, I; Wadsack, C; Desoye, G
THE FETAL HYPDXIC ENVIRONMENT OF GDM ALTERS VEGF AND FGF2 RECEPTORS IN THE VENOUS BUT NOT ARTERIAL FETO-PLACENTAL VASCULATURE
PLACENTA. 2015; 36(4):476-476.-6th Latin American Symposium on Maternal-Fetal Interaction and Placenta / 5th Latin American Symposium on Reproductive Immunology; APR 13-16, 2015; Mar del Plata, ARGENTINA.
Doi: 10.1016/j.placenta.2015.01.404
[Oral Communication]
Web of Science
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** Sreckovic, I; Sommer, NG; Bernhart, E; Lang, U; Desoye, G; Christian, W
FETAL HDL IN GESTATIONAL DIABETES MELLITUS (GDM) AFFECTS FETOPLACENTAL ENDOTHELIAL BARRIER INTEGRITY: RELATIONSHIP WITH HDL-ASSOCIATED SIP-APO COMPLEX
PLACENTA. 2015; 36(4): 475-475.
Doi: 10.1016/j.placenta.2015.01.402
[Keynote lecture]
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** Zardoya Laguardia, P; Blaschitz, A; Lang, I; Gauster, M; Frank, S; Wadsack, C; Haeusler, M; Cervar-Zivkovic, M; Sedlmayr, P
Tryptophan regulates the chorionic vascular tone and chorionic endothelial indoleamine 2,3-dioxygenase-1 is deficient in intrauterine growth restriction and preeclampsia
J REPROD IMMUNOL. 2015; 111: 17-17.-Annual Meeting of the European-Society-for-Reproductive-Immunology; SEP 21-24, 2015; Oxford, ENGLAND.
Doi: 10.1016/j.jri.2015.06.088
[Oral Communication]
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** El-Gamal, D; Rao, SP; Holzer, M; Hallström, S; Haybaeck, J; Gauster, M; Wadsack, C; Kozina, A; Frank, S; Schicho, R; Schuligoi, R; Heinemann, A; Marsche, G
The urea decomposition product cyanate promotes endothelial dysfunction.
Kidney Int. 2014; 86(5):923-931
Doi: 10.1038/ki.2014.218
[OPEN ACCESS]
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** Sreckovic, I; Birner-Gruenberger, R; Besenboeck, C; Miljkovic, M; Stojakovic, T; Scharnagl, H; Marsche, G; Lang, U; Kotur-Stevuljevic, J; Jelic-Ivanovic, Z; Desoye, G; Wadsack, C
Gestational diabetes mellitus modulates neonatal high-density lipoprotein composition and its functional heterogeneity.
Biochim Biophys Acta. 2014; 1841(11):1619-1627
Doi: 10.1016/j.bbalip.2014.07.021
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** van Poppel, MN; Zeck, W; Ulrich, D; Schest, EC; Hirschmugl, B; Lang, U; Wadsack, C; Desoye, G
Cord blood chemerin: differential effects of gestational diabetes mellitus and maternal obesity.
Clin Endocrinol (Oxf). 2014; 80(1):65-72
Doi: 10.1111/cen.12140
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** Besenboeck, C; Hirschmugl, B; Bilic, J; Desoye, G; Wadsack, C
LPPLA(2) AND SIRT1-NOVEL REGULATORS OF INFLAMMATION IN PLACENTAL TISSUE IN DIABETES AND OBESITY?
PLACENTA. 2014; 35(9):A28-A28.-International-Federation-of-Placenta-Associations (IFPA)/EPG Meeting; SEP 09-12, 2014; Paris, FRANCE.
Doi: 10.1016/j.placenta.2014.06.094
[Poster]
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** Frank, S; Opresnik, S; Rao, SP; Hrzenjak, A; Hallstrom, S; Kozina, A; Sreckovic, I; Wadsack, CH; Holzer, M; Marsche, G; Birner-Gruenberger, R; Stojakovic, T; Scharnagl, H
ENDOTHELIAL LIPASE ATTENUATES VASORELAXING CAPACITY OF HDL
ATHEROSCLEROSIS. 2014; 235(2): E45-E45.
Doi: 10.1016/j.atherosclerosis.2014.05.102
[Poster]
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** Nikitina, L; Blaschitz, A; Gauster, M; Besenbock, C; Wadsack, C; Desoye, G; Sedlmayr, P
EXPRESSION AND LOCALIZATION OF THE TRYPTOPHAN-DEGRADING ENZYMES TRYPTOPHAN 2,3-DIOXYGENASE AND INDOLEAMINE 2,3-DIOXYGENASE-2 IN THE HUMAN PLACENTA
PLACENTA. 2014; 35(9): A68-A69.
Doi: 10.1016/j.placenta.2014.06.222
[Poster]
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** Abumaree, MH; Brownbill, P; Burton, G; Castillo, C; Chamley, L; Croy, BA; Drewlo, S; Dunk, C; Girard, S; Hansson, S; Jones, S; Jurisicova, A; Lewis, R; Letarte, M; Parast, M; Pehrson, C; Rappolee, D; Schneider, H; Tannetta, D; Varmuza, S; Wadsack, C; Wallace, AE; Zenerino, C; Lash, GE
IFPA Meeting 2013 Workshop Report III: maternal placental immunological interactions, novel determinants of trophoblast cell fate, dual ex vivo perfusion of the human placenta.
Placenta. 2014; 35 Suppl(3):S15-S19
Doi: 10.1016/j.placenta.2013.11.009
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** Holzer, M; Trieb, M; Konya, V; Wadsack, C; Heinemann, A; Marsche, G
Aging affects high-density lipoprotein composition and function.
Biochim Biophys Acta. 2013; 1831(9):1442-1448
Doi: 10.1016/j.bbalip.2013.06.004
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** Sreckovic, I; Birner-Gruenberger, R; Obrist, B; Stojakovic, T; Scharnagl, H; Holzer, M; Scholler, M; Philipose, S; Marsche, G; Lang, U; Desoye, G; Wadsack, C
Distinct composition of human fetal HDL attenuates its anti-oxidative capacity.
Biochim Biophys Acta. 2013; 1831(4):737-746
Doi: 10.1016/j.bbalip.2012.12.015
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** Sreckovic, I; Sommer, N; Bernhart, E; Lang, U; Desoye, G; Wadsack, C
Fetal HDL-Associated ApoM-S1P Complex Mediates Vasoprotective Action on the Feto-Placental Endothelium. In Gestational Diabetes Mellitus (GDM) Endothelial Barrier Integrity Is Impaired
REPROD SCI. 2013; 20(S3):249A-249A.-60th Annual Scientific Meeting of the Society-for-Gynecologic-Investigation (SGI); MAR 20-23, 2013; Orlando, FL.
[Poster]
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** Sreckovic, I; Sommer, NG; Bernhart, E; Sattler, W; Desoye, G; Lang, U; Wadsack, C;
FETAL HDL-ASSOCIATED APOM-S1P COMPLEX MEDIATES VASO-PROTECTIVE ACTION ON THE FETO-PLACENTAL ENDOTHELIUM. IN GESTATIONAL DIABETES MELLITUS (GDM) ENDOTHELIAL BARRIER INTEGRITY IS IMPAIRED.
PLACENTA. 2013; 34(9):A19-A19.-Meeting of the International-Federation-of-Placenta-Associations (IFPA); SEP 11-14, 2013; Whistler, CANADA.
Doi: 10.1016/j.placenta.2013.06.058
[Poster]
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** El-Gamal, D; Holzer, M; Gauster, M; Schicho, R; Binder, V; Konya, V; Wadsack, C; Schuligoi, R; Heinemann, A; Marsche, G
Cyanate is a novel inducer of endothelial icam-1 expression.
Antioxid Redox Signal. 2012; 16(2): 129-137.
Doi: 10.1089/ars.2011.4090
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** Holzer, M; Wolf, P; Curcic, S; Birner-Gruenberger, R; Weger, W; Inzinger, M; El-Gamal, D; Wadsack, C; Heinemann, A; Marsche, G
Psoriasis alters HDL composition and cholesterol efflux capacity.
J Lipid Res. 2012; 53(8):1618-1624
Doi: 10.1194/jlr.M027367
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** Scholler, M; Wadsack, C; Lang, I; Etschmaier, K; Schweinzer, C; Marsche, G; Dieber-Rotheneder, M; Desoye, G; Panzenboeck, U
Phospholipid transfer protein in the placental endothelium is affected by gestational diabetes mellitus.
J Clin Endocrinol Metab. 2012; 97(2): 437-445.
Doi: 10.1210/jc.2011-1942
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** Scholler, M; Wadsack, C; Metso, J; Chirackal Manavalan, AP; Sreckovic, I; Schweinzer, C; Hiden, U; Jauhiainen, M; Desoye, G; Panzenboeck, U
Phospholipid Transfer Protein Is Differentially Expressed in Human Arterial and Venous Placental Endothelial Cells and Enhances Cholesterol Efflux to Fetal HDL.
J Clin Endocrinol Metab. 2012; 97(7):2466-2474
Doi: 10.1210/jc.2011-2969
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** Ulrich, D; Desoye, G; Wadsack, C; Haas, J; Csapo, B; Holzapfel-Bauer, M; Lang, U; Schlembach, D
Fetal anterior wall thickness and amniotic fluid insulin levels: an interdependence?
Ultraschall Med. 2012; 33(7):E108-E113
Doi: 10.1055/s-0029-1245926
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** Wadsack, C; Desoye, G; Hiden, U
The feto-placental endothelium in pregnancy pathologies.
Wien Med Wochenschr. 2012; 162(9-10):220-224
Doi: 10.1007/s10354-012-0075-2
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** Acharya, G; Albrecht, C; Benton, SJ; Cotechini, T; Dechend, R; Dilworth, MR; Duttaroy, AK; Grotmol, T; Heazell, AE; Jansson, T; Johnstone, ED; Jones, HN; Jones, RL; Lager, S; Laine, K; Nagirnaja, L; Nystad, M; Powell, T; Redman, C; Sadovsky, Y; Sibley, C; Troisi, R; Wadsack, C; Westwood, M; Lash, GE
IFPA Meeting 2011 workshop report I: Placenta: Predicting future health; roles of lipids in the growth and development of feto-placental unit; placental nutrient sensing; placental research to solve clinical problems--a translational approach.
Placenta. 2012; 33 Suppl(3):S4-S8
Doi: 10.1016/j.placenta.2011.11.015
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** Augsten, M; Hackl, H; Ebner, B; Chemelli, A; Glatter, O; Marsche, G; Lang, U; Desoye, G; Wadsack, C
Fetal HDL/apoE: a novel regulator of gene expression in human placental endothelial cells.
Physiol Genomics. 2011; 43(22):1255-1262
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** Gauster, M; Hiden, U; Vanpoppel, M; Frank, S; Wadsack, C; Hauguel-de Mouzon, S; Desoye, G
Dysregulation of placental endothelial lipase in obese women with gestational diabetes mellitus.
Diabetes. 2011; 60(10): 2457-2464.
Doi: 10.2337/db10-1434
[OPEN ACCESS]
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** Holzer, M; Birner-Gruenberger, R; Stojakovic, T; El-Gamal, D; Binder, V; Wadsack, C; Heinemann, A; Marsche, G
Uremia Alters HDL Composition and Function.
J Am Soc Nephrol. 2011; 22(9):1631-1641
Doi: 10.1681/ASN.2010111144
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** Holzer, M; Gauster, M; Pfeifer, T; Wadsack, C; Fauler, G; Stiegler, P; Koefeler, H; Beubler, E; Schuligoi, R; Heinemann, A; Marsche, G
Protein carbamylation renders high-density lipoprotein dysfunctional.
Antioxid Redox Signal. 2011; 14(12): 2337-2346.
Doi: 10.1089/ars.2010.3640
[OPEN ACCESS]
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** Korgun, ET; Unek, G; Herrera, E; Jones, CJ; Wadsack, C; Kipmen-Korgun, D; Desoye, G
Mapping of CIP/KIP inhibitors, G1 cyclins D1, D3, E and p53 proteins in the rat term placenta.
Histochem Cell Biol. 2011; 136(3):267-278
Doi: 10.1007/s00418-011-0841-z
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** Moertl, M; Friedrich, S; Kraschl, J; Wadsack, C; Lang, U; Schlembach, D
Haemodynamic effects of carbetocin and oxytocin given as intravenous bolus on women undergoing caesarean delivery: a randomised trial.
BJOG. 2011; 118(11): 1349-1356.
Doi: 10.1111/j.1471-0528.2011.03022.x
[OPEN ACCESS]
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** Desoye, G; Gauster, M; Wadsack, C
Placental transport in pregnancy pathologies.
Am J Clin Nutr. 2011; 94(6 Suppl):1896S-11902
Doi: 10.3945/ajcn.110.000851
[OPEN ACCESS]
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** Moertl, MG; Friedrich, S; Kraschl, J; Wadsack, C; Lang, U; Schlembach, D
Haemodynamic effects of carbetocin and oxytocin given as intravenous bolus on women undergoing caesarean delivery: a randomised trial (vol 118, pg 1349, 2011)
BJOG-INT J OBSTET GY. 2011; 118(12): 1549-1549.
Doi: 10.1111/j.1471-0528.2011.03148.x
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** Sreckovic, I; Birner-Gruenberger, R; Philipose, S; Holzer, M; Marsche, G; Desoye, G; Lang, U; Wadsack, C
APOLIPOPROTEINS (APO) ACCOUNTS FOR THE ANTI-INFLAMMATORY FUNCTION OF FETAL HDL
PLACENTA. 2011; 32(9):A112-A112.-Meeting of the International-Federation-of-Placenta-Associations (IFPA); SEP 14-17, 2011; Geilo, NORWAY.
[Poster]
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** Augsten, M; Wolkart, G; Schmidt, K; Mayer, B; Desoye, G; Wadsack, C
HIGH DENSITY LIPOPROTEIN (HDL) REGULATES PLACENTAL VASCULAR TONE INDEPENDENT OF ENDOTHELIAL NITRIC OXIDE SYNTHASE (ENOS)
PLACENTA. 2010; 31(9): A10-A10.
[Poster]
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** Holzer, M; Gauster, M; Wadsack, C; Marsche, G
Cyanate selectively disrupts anti-atherogenic activities of high-density lipoprotein in human atherosclerotic lesions
EUR HEART J. 2010; 31: 250-250.
[Poster]
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** Scholler, M; Wadsack, C; Lang, I; Etschmaier, K; Schweinzer, C; Becker, T; Björkhem, I; Desoye, G; Panzenböck, U
PHOSPHOLIPID TRANSFER PROTEIN IS EXPRESSED AND ACTIVE IN HUMAN PLACENTAL ENDOTHELIAL CELLS
PLACENTA. 2010; 31(9): A130-A130.
[Poster]
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** Ulrich, D; Moertl, M; Holzapfel-Bauer, M; Desoye, G; Wadsack, C; Mayer-Pickel, K; Eder, M; Lang, U; Schlembach, D
Fetal Anterior Abdominal Wall Thickness and Amniotic Fluid Insulin Levels - An Interdependence?
REPROD SCI. 2010; 17(3): 505
[Poster]
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** Marsche, G; Frank, S; Hrzenjak, A; Holzer, M; Dirnberger, S; Wadsack, C; Scharnagl, H; Stojakovic, T; Heinemann, A; Oettl, K
Plasma-advanced oxidation protein products are potent high-density lipoprotein receptor antagonists in vivo.
Circ Res. 2009; 104(6): 750-757.
Doi: 10.1161/CIRCRESAHA.108.193169
[OPEN ACCESS]
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** Stefulj, J; Panzenboeck, U; Becker, T; Hirschmugl, B; Schweinzer, C; Lang, I; Marsche, G; Sadjak, A; Lang, U; Desoye, G; Wadsack, C
Human endothelial cells of the placental barrier efficiently deliver cholesterol to the fetal circulation via ABCA1 and ABCG1.
Circ Res. 2009; 104(5):600-608
Doi: 10.1161/CIRCRESAHA.108.185066
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** Hiden, U; Glitzner, E; Ivanisevic, M; Djelmis, J; Wadsack, C; Lang, U; Desoye, G
MT1-MMP expression in first-trimester placental tissue is upregulated in type 1 diabetes as a result of elevated insulin and tumor necrosis factor-alpha levels.
Diabetes. 2008; 57(1): 150-157.
Doi: 10.2337/db07-0903
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** Eder, M, Pickel, MEK; Ulrich, D; Giuliani, A; Moeller, R; Horejsi, R; Wadsack, C; Desoye, G; Reiterer, F; Lang, U; Schlembach, D
SUBCUTANEOUS ADIPOSE TISSUE TOPOGRAPHY IN NEONATES
AMER J OBSTET GYNECOL. 2008; 199(6):345--28th Annual Meeting of the Society-for-Maternal-Fetal-Medicine; JAN 28-FEB 02, 2008; Dallas, TX.
Doi: 10.1016/j.ajog.2008.09.373
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** Panzenboeck, U; Becker, T; Stefulj, J; Hirschmugl, B; Schweinzer, C; Marsche, G; Lang, U; Desoye, G; Wadsack C
ATP-binding cassette transporters A1 and G1 promote cholesterol efflux from fetal endothelial cells of human placenta.
Placenta. 2008; 29(8):A11--European Placenta Group Meeting
14th IFPA Congress; SEP 10-13; Seggau Castle Austria.
[Poster]
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** Panzenboeck, U; Stefulj, J; Schweinzer, C; Wadsack, C; Moertl, M; Desoye, G
Cholesterol efflux mechanisms in endothelial cells of the human placenta
REPROD SCI. 2008; 15(2): 92A-92A.
[Poster]
Web of Science
** Wadsack, C; Augsten, M; Guelly, C; Hiden, U; Lang, I; Moert, M; Lang, U; Desoye, G.
Differential expression of scavenger receptor class B type-I between arterial and venous placental endothelial cells is not the result of epigenetic regulation.
REPROD SCI. 2008; 15(2): 204A-204A.
[Oral Communication]
Web of Science
** Gauster, M; Hiden, U; Blaschitz, A; Frank, S; Lang, U; Alvino, G; Cetin, I; Desoye, G; Wadsack, C
Dysregulation of placental endothelial lipase and lipoprotein lipase in intrauterine growth-restricted pregnancies.
J Clin Endocrinol Metab. 2007; 92(6):2256-2263
Doi: 10.1210/jc.2006-2403
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** Hiden, U; Wadsack, C; Prutsch, N; Gauster, M; Weiss, U; Frank, HG; Schmitz, U; Fast-Hirsch, C; Hengstschlager, M; Potgens, A; Ruben, A; Knofler, M; Haslinger, P; Huppertz, B; Bilban, M; Kaufmann, P; Desoye, G
The first trimester human trophoblast cell line ACH-3P: a novel tool to study autocrine/paracrine regulatory loops of human trophoblast subpopulations--TNF-alpha stimulates MMP15 expression.
BMC Dev Biol. 2007; 7(6): 137-137.
Doi: 10.1186/1471-213X-7-137
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** Wadsack, C; Tabano, S; Maier, A; Hiden, U; Alvino, G; Cozzi, V; Hüttinger, M; Schneider, WJ; Lang, U; Cetin, I; Desoye, G
Intrauterine growth restriction is associated with alterations in placental lipoprotein receptors and maternal lipoprotein composition.
Am J Physiol Endocrinol Metab. 2007; 292(2): E476-E484.
Doi: 10.1152/ajpendo.00547.2005
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** Desoye, G; Stefujl, J; Schweinzer, C; Panzenboeck, U; Wadsack, C;
Cholesterol Efflux In Human Placental Endothelial Cells.
Placenta2007; 28(8-9):A26-A26.-International Federation of Placenta Association Meeting ; AUG 17-22, 2007; Kingston, Ontario, CANADA.
[Poster]
Web of Science
** Stangl, H; Pagler, T; Golsabahi, S; Laggner, H; Lohininger, A; Rhode, S; Schutz, GJ; Pavelka, M; Wadsack, C; Strobl, W
A Chinese hamster ovarian cell line imports cholesterol by high density lipoprotein degradation
FEBS J. 2007; 274: 269-269.
[Poster]
Web of Science
** Hiden, U; Maier, A; Bilban, M; Ghaffari-Tabrizi, N; Wadsack, C; Lang, I; Dohr, G; Desoye, G
Insulin control of placental gene expression shifts from mother to foetus over the course of pregnancy.
DIABETOLOGIA. 2006; 49(1): 123-131.
Doi: 10.1007/s00125-005-0054-x
[OPEN ACCESS]
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** Pagler, TA; Golsabahi, S; Doringer, M; Rhode, S; Schütz, GJ; Pavelka, M; Wadsack, C; Gauster, M; Lohninger, A; Laggner, H; Strobl, W; Stangl, H
A Chinese hamster ovarian cell line imports cholesterol by high density lipoprotein degradation.
J Biol Chem. 2006; 281(50): 38159-38171.
Doi: 10.1074/jbc.M603334200
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** Hiden, U; Wadsack, C; Tabano, S; Radaelli, T; Cetin, I; Desoye, G
Differential insulin receptor splicing in trophoblast vs endothelial cells
PLACENTA. 2006; 27(9-10):A17-A17.
[Oral Communication]
Web of Science
** Hiden, U; Maier, A; Ghaffari-Tabrizi, N; Wadsack, C; Desoye, G
Differential insulin receptor expression causes differential insulin signalling in the two interfaces of the human placenta.
PLACENTA 2005 26: A9-A9.
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** Hiden, U; Maier, A; Ghaffari-Tabrizzi, N; Wadsack, C; Desoye, G
Differential insulin signalling in placental trophoblasts and endothelial cells is the result of differences in their insulin receptor isoform expression.
J SOC GYNECOL INVESTIGATION 2005 12: 179A-179A.
Web of Science
** Hiden, U; Maier, A; Michelmaier, R; Prutsch, N; Wadsack, C; Lang, I; Desoye, G
Insulin activation of different signalling pathways in cells of the maternal and fetal surface of the human placenta correlates with different insulin receptor isoforms
DIABETES. 2005; 54: A460-A460.
Web of Science
** Wadsack, C; Hirschmugl, B; Maier, A; Hiden, U; Desoye, G
The placental scavenger receptor class B type-I (SR-BI) undergoes spatio-developmental changes in human pregnancy.
PLACENTA 2005 26: A49-A49.
Web of Science
** Wadsack, C; Tabano, S; Alvino, G; Cozzi, V; Desoye, G; Cetin, I
Severe intrauterine growth restriction (IUGR) is associated with impaired lipoprotein receptor expression levels in human placenta.
J SOC GYNECOL INVESTIGATION. 2005; 12: 112A-112A.-52nd Annual Meeting of the Society-for-Gynecologic-Investigation; MAR 23-26, 2005; Los Angeles, CA.
Web of Science
** Tabano, S; Wadsack, C; ALvino, G; Desoye, G; Cetin, I
Only severe intrauterine growth restriction (IUGR) alters expression levels of low density lipoprotein receptor-related protein (LRP) and scavenger receptor class B type I (SR-BI)
PLACENTA 2004 25: A12-A12.
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** Wadsack, C; Prutsch, N; Frank, HG; Schmitz, U; Weiss, U; Kaufmann, R; Desoye, G
Ach-3P: A continuous cell line derived from first trimester human trophoblast
PLACENTA 2004 25: A61-A61.
Web of Science
** Wadsack, C; Tabano, S; Alvino, G; Ortega, H; Herrera, E; Cetin, I; Desoye, G
Gestational diabetes modifies scavenger receptor class B type I receptor (SR-BI) expression in human placental tissue
PLACENTA 2004 25: A61-A61.
Web of Science
** Wadsack, C; Hammer, A; Levak-Frank, S; Desoye, G; Kozarsky, KF; Hirschmugl, B; Sattler, W; Malle, E
Selective cholesteryl ester uptake from high density lipoprotein by human first trimester and term villous trophoblast cells.
Placenta. 2003; 24(2-3):131-143
Doi: 10.1053/plac.2002.0912
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** Wadsack, C; Hirschmugl, B; Hammer, A; Levak-Frank, S; Kozarsky, KF; Sattler, W; Malle, E
Scavenger receptor class B, type I on non-malignant and malignant human epithelial cells mediates cholesteryl ester-uptake from high density lipoproteins.
Int J Biochem Cell Biol. 2003; 35(4):441-454
Doi: 10.1016/S1357-2725(02)00272-8
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** Wadsack, C; Hrzenjak, A; Hammer, A; Hirschmugl, B; Levak-Frank, S; Desoye, G; Sattler, W; Malle, E
Trophoblast-like human choriocarcinoma cells serve as a suitable in vitro model for selective cholesteryl ester uptake from high density lipoproteins.
Eur J Biochem. 2003; 270(3):451-462
Doi: 10.1046%2Fj.1432-1033.2003.03394.x
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** Wadsack, C; Hammer, A; Levak-Frank, S; Sattler, W; Desoye, G; Malle, E
Scavenger receptor class B type I represents an efficient route for supplying cholesterol esters from maternal lipoproteins to developing embryonic tissues
MOL BIOL CELL 2002 13: 640-640.
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