Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Silbert-Wagner Dagmar |
** = Publikationen gelistet in SCI/SSCI/Pubmed
2024
Originalarbeit (Zeitschrift)
** Behrens, J; Braren, I; Jaeckstein, MY; Lilie, L; Heine, M; Sass, F; Sommer, J; Silbert-Wagner, D; Fuh, MM; Worthmann, A; Straub, L; Moustafa, T; Heeren, J; Scheja, L
An efficient AAV vector system of Rec2 serotype for intravenous injection to study metabolism in brown adipocytes in vivo.
Mol Metab. 2024; 101999
Doi: 10.1016/j.molmet.2024.101999
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
2013
Originalarbeit (Zeitschrift)
** Fickert, P; Krones, E; Pollheimer, MJ; Thueringer, A; Moustafa, T; Silbert, D; Halilbasic, E; Yang, M; Jaeschke, H; Stokman, G; Wells, RG; Eller, K; Rosenkranz, AR; Eggertsen, G; Wagner, CA; Langner, C; Denk, H; Trauner, M
Bile acids trigger cholemic nephropathy in common bile-duct-ligated mice.
Hepatology. 2013; 58(6):2056-2069
Doi: 10.1002/hep.26599
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
** Fickert, P; Pollheimer, MJ; Silbert, D; Moustafa, T; Halilbasic, E; Krones, E; Durchschein, F; Thüringer, A; Zollner, G; Denk, H; Trauner, M
Differential effects of norUDCA and UDCA in obstructive cholestasis in mice.
J Hepatol. 2013; 58(6):1201-1208
Doi: 10.1016/j.jhep.2013.01.026
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
2012
Originalarbeit (Zeitschrift)
** Fuchs, CD; Claudel, T; Kumari, P; Haemmerle, G; Pollheimer, MJ; Stojakovic, T; Scharnagl, H; Halilbasic, E; Gumhold, J; Silbert, D; Koefeler, H; Trauner, M
Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice.
Hepatology. 2012; 56(1):270-280
Doi: 10.1002/hep.25601
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
** Lax, S; Schauer, G; Prein, K; Kapitan, M; Silbert, D; Berghold, A; Berger, A; Trauner, M
Expression of the nuclear bile acid receptor/farnesoid X receptor is reduced in human colon carcinoma compared to nonneoplastic mucosa independent from site and may be associated with adverse prognosis.
Int J Cancer. 2012; 130(10): 2232-2239.
Doi: 10.1002/ijc.26293
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Silbert, D; Gustafsson, U; Sahlin, S; Trauner, M
Combined rifampicin and ursodeoxycholic acid treatment does not amplify rifampicin effects on hepatic detoxification and transport systems in humans.
Digestion. 2012; 86(3):244-249
Doi: 10.1159/000341420
Web of Science
PubMed
FullText
FullText_MUG
** Moustafa, T; Fickert, P; Magnes, C; Guelly, C; Thueringer, A; Frank, S; Kratky, D; Sattler, W; Reicher, H; Sinner, F; Gumhold, J; Silbert, D; Fauler, G; Höfler, G; Lass, A; Zechner, R; Trauner, M
Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.
Gastroenterology. 2012; 142(1):140-151
Doi: 10.1053/j.gastro.2011.09.051
Web of Science
PubMed
FullText
FullText_MUG
Abstract (Zeitschrift)
** Marschall, HU; Mueller, M; Wagner, M; Fickert, P; Zollner, G; Silbert, D; Lackner, C; Thorell, A; Trauner, M
HIGH LEVELS OF URSODEOXYCHOLIC ACID ACT AS FXR ANTAGONIST AND DEPLETE LIVER CHOLESTEROL DUE TO INCREASED BILE ACID SYNTHESIS IN MORBIDLY OBESE PATIENTS
J HEPATOL. . 2012; 56: S515-S515.-47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 18-22, 2012; Barcelona, SPAIN.
Doi: 10.1016/S0168-8278(12)61319-1
[Poster]
Web of Science
FullText
FullText_MUG
2011
Originalarbeit (Zeitschrift)
** Baghdasaryan, A; Claudel, T; Gumhold, J; Silbert, D; Adorini, L; Roda, A; Vecchiotti, S; Gonzalez, FJ; Schoonjans, K; Strazzabosco, M; Fickert, P; Trauner, M
Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO⁻₃ output.
Hepatology. 2011; 54(4):1303-1312
Doi: 10.1002/hep.24537
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
Abstract (Zeitschrift)
** Baghdasaryan, A; Claudel, T; Gumhold, J; Silbert, D; Adorini, L; Gonzalez, F; Schoonjans, K; Fickert, P; Trauner, M
FXR BUT NOT TGR5 ACTIVATION STIMULATES HCO3-RICH BILE SECRETION AND AMELIORATES LIVER DAMAGE IN MDR2-/- (ABCB4-/-) MOUSE MODEL OF CHRONIC LIVER INJURY
HEPATOLOGY. 2011; 54: 425A-425A.-62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 04-08, 2011; San Francisco, CA.
[Oral Communication]
Web of Science
** Fickert, P; Silbert, D; Moustafa, T; Halilbasic, E; Krones, E; Durchschein, F; Thueringer, A; Pollheimer, MJ; Zollner, G; Denk, H; Trauner, M
DIFFERENTIAL EFFECTS OF NORUDCA AND UDCA IN OBSTRUCTIVE CHOLESTASIS IN MICE
HEPATOLOGY. 2011; 54: 775A-775A.-62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 04-08, 2011; San Francisco, CA.
[Poster]
Web of Science
** Fickert, P; Thueringer, A; Moustafa, T; Silbert, D; Yang, M; Jaeschke, H; Stokman, G; Wells, R; Eller, K; Rosenkranz, AR; Eggertsen, G; Denk, H; Trauner, M
TUBULOINTERSTITIAL KIDNEY FIBROSIS AND CHRONIC RENAL FAILURE IN LONG-TERM COMMON BILE-DUCT-LIGATED MICE AS A RESULT OF COLLECTING DUCT INJURY: THE ROLE OF OSTEOPONTIN, FXR, AND CYP8B1
HEPATOLOGY. 2011; 54: 1250A-1251A.-62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 04-08, 2011; San Francisco, CA.
Web of Science
** Fuchs, CD; Claudel, T; Kumari, P; Stojakovic, T; Haemmerle, G; Halilbasic, E; Gumhold, J; Silbert, D; Koefeler, H; Zechner, R; Trauner, M
ATGL (PNPLA2) KNOCKOUT MICE ARE PROTECTED FROM HEPATIC ER-STRESS VIA OLEIC ACID ACCUMULATION.
J HEPATOL. 2011; 54: S41-S42.-46th Annual Meeting of the European Association for the Study of the Liver (EASL); MAR 30-APR 3, 2011; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(11)60095-0
[Poster]
Web of Science
FullText
FullText_MUG
** Fuchs, CD; Claudel, T; Stojakovic, T; Silbert, D; Maurer, B; Trauner, M
BSEP (ABCB11) KO MICE ARE PROTECTED FROM HEPATIC INFLAMMATION IN METHIONINE CHOLINE DEFICIENT DIET INDUCED NASH.
HEPATOLOGY. 2011; 54: 1169A-1169A.-62nd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); NOV 04-08, 2011; San Francisco, USA.
[Poster]
Web of Science
2010
Originalarbeit (Zeitschrift)
** Baghdasaryan, A; Claudel, T; Kosters, A; Gumhold, J; Silbert, D; Thüringer, A; Leski, K; Fickert, P; Karpen, SJ; Trauner, M
Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation.
Gut. 2010; 59(4):521-530
Doi: 10.1136/gut.2009.186528
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
** Fickert, P; Thueringer, A; Moustafa, T; Silbert, D; Gumhold, J; Tsybrovskyy, O; Lebofsky, M; Jaeschke, H; Denk, H; Trauner, M
The role of osteopontin and tumor necrosis factor alpha receptor-1 in xenobiotic-induced cholangitis and biliary fibrosis in mice.
Lab Invest. 2010; 90(6):844-852
Doi: 10.1038/labinvest.2010.61
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
Abstract (Zeitschrift)
** Baghdasaryan, A; Claudel, T; Gumhold, J; Silbert, D; Halsegger, S; Adorini, L; Strazzabosco, M; Fickert, P; Trauner, M
THERAPEUTIC TARGETING OF NUCLEAR AND MEMBRANE BILE ACID RECEPTORS IN A MOUSE MODEL OF CHRONIC CHOLESTASIS
HEPATOLOGY. 2010; 52(4):724--The 61st Annual Meeting of the Americal Association fro teh Study of liver Diseases; OCT 29-NOV 02, 2010; Boston, MA, USA.
[Poster]
Web of Science
** Baghdasaryan, A; Claudel, T; Gumhold, J; Silbert, D; Halsegger, S; Volkl, R; Adorini, L; Fickert, P; Trauner, M
THERAPEUTIC EFFECTS OF FXR AND TGR5 ACTIVATION IN THE MDR2 (ABCB4)(-/-) MOUSE MODEL OF SCLEROSING CHOLANGITIS
J HEPATOL. 2010; 52: S354-S354.-45th Annual Meeting of the European Association for the Study of the Liver; APR 14 - 18,2010; Vienna, AUSTRIA.
Doi: 10.1016/S0168-8278(10)60914-2
[Oral Communication]
Web of Science
FullText
FullText_MUG
** Fuchs, CD; Moustafa, T; Haemmerle, G; Halilbasic, E; Gumhold, J; Silbert, D; Fickert, P; Zechner, R; Trauner, M
ADIPOSE TRIGLYCERIDE LIPASE (ATGL) IS A NOVEL MODULATOR OF HEPATIC ER-STRESS
J HEPATOL. 2010; 52: S305-S305.-45th Annual Meeting of the European Association for the Study of the Liver; APR 14 - 18,2010; Vienna, AUSTRIA.
Doi: 10.1016/S0168-8278(10)60787-8
[Oral Communication]
Web of Science
FullText
FullText_MUG
** Halilbasic, E; Claudel, T; Gumhold, J; Halsegger, S; Silbert, D; Fickert, P; Trauner, M
PREGNANCY RESOLVES LIVER FIBROSIS AND IMPROVES SCLEROSING CHOLANGITIS IN MDR2 (ABCB4) -/- MICE VIA DIRECT ANTI-INFLAMMATORY EFFECTS OF SEX HORMONES
J HEPATOL. 2010; 52: S24-S24.-45th Annual Meeting of the European Association for the Study of the Liver; APR 14 - 18,2010; Vienna, AUSTRIA.
Doi: 10.1016/S0168-8278(10)60052-9
[Oral Communication]
Web of Science
FullText
FullText_MUG
** Moustafa, T; Fickert, P; Magnes, C; Frank, S; Kratky, D; Sinner, F; Gumhold, J; Silbert, D; Halsegger, S; Trauner M
METABOLIC REPROGRAMMING OF LIPID METABOLISM BY THE SIDE-CHAIN MODIFIED BILE ACID, 24-NORURSODEOXYCHOLIC ACID, RESTORES INFLAMMATION-DRIVEN LIVER INJURY AND ABERRANT PROLIFERATION IN ABCB4-/- MICE
J HEPATOL. 2010; 52: S20-S21.-45th Annual Meeting of the European Association for the Study of the Liver; APR 14 - 18,2010; Vienna, AUSTRIA.
Doi: 10.1016/S0168-8278(10)60049-9
[Oral Communication]
Web of Science
FullText
FullText_MUG
2009
Originalarbeit (Zeitschrift)
** Fickert, P; Fuchsbichler, A; Wagner, M; Silbert, D; Zatloukal, K; Denk, H; Trauner, M
The role of the hepatocyte cytokeratin network in bile formation and resistance to bile acid challenge and cholestasis in mice.
Hepatology. 2009; 50(3):893-899
Doi: 10.1002/hep.23068
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
** Halilbasic, E; Fiorotto, R; Fickert, P; Marschall, HU; Moustafa, T; Spirli, C; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Langner, C; Maitra, U; Denk, H; Hofmann, AF; Strazzabosco, M; Trauner, M
Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice.
Hepatology. 2009; 49(6):1972-1981
Doi: 10.1002/hep.22891
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
Pressetext
Google Scholar
** Jahnel, J; Fickert, P; Langner, C; Högenauer, C; Silbert, D; Gumhold, J; Fuchsbichler, A; Trauner, M
Impact of experimental colitis on hepatobiliary transporter expression and bile duct injury in mice.
Liver Int. 2009; 29(9):1316-1325
Doi: 10.1111/j.1478-3231.2009.02044.x
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
** Loebermann, M; Sombetzki, M; Langner, C; Fuchsbichler, A; Gumhold, J; Silbert, D; Riebold, D; Holtfreter, M; Fickert, P; Nizze, H; Trauner, M; Reisinger, EC
Imbalance of pro- and antifibrogenic genes and bile duct injury in murine Schistosoma mansoni infection-induced liver fibrosis.
Trop Med Int Health. 2009; 14(11):1418-1425
Doi: 10.1111/j.1365-3156.2009.02387.x
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
Abstract (Zeitschrift)
** Jahnel, J; Claudel, T; Baghdasaryan, A; Langner, C; Fickert, P; Trauner, M; Hauer, AC; Silbert, A; Gumhold, J; Fuchsbichler, A
PHOSPHOLIPIDS AND COLITIS: IMPACT OF NUTRITIONAL AND BILIARY LACK OF PHOSPHOLIPIDS IN A COLITIS MOUSE MODEL
ACTA PAEDIAT. 2009; 98: 29-30.-50th Annual Meeting of the European Society for Paediatric Research ; October 9-12, 2009 ; Hamburg, Germany.
[Oral Communication]
Web of Science
Originalarbeit (Konferenzband)
** Halilbasic, E; Fickert, P; Fiorotto, R; Marschall, HU; Moustafa, T; Fuchsbichler, A; Gumhold, J; Silbert, D; Langner, C; Maitra, U; Denk, H; Strazzabosco, M; Trauner, M
Side-chain modification as critical determinant of the therapeutic properties of 24-norursodeoxycholic acid in Mdr2 (Abcb4) knockout mice
FALK SYMP. 2009; 165: 157-162.
[Oral Communication]
Web of Science
2008
Originalarbeit (Zeitschrift)
** Baghdasaryan, A; Fickert, P; Fuchsbichler, A; Silbert, D; Gumhold, J; Hörl, G; Langner, C; Moustafa, T; Halilbasic, E; Claudel, T; Trauner, M
Role of hepatic phospholipids in development of liver injury in Mdr2 (Abcb4) knockout mice.
Liver Int. 2008; 28(7):948-958
Doi: 10.1111/j.1478-3231.2008.01758.x
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
Abstract (Zeitschrift)
** Baghdasaryan, A; Kosters, A; Claudel, T; Fuchsbichler, A; Gumhold, J; Silbert, D; Leski, K; Fickert, P; Karpen, SJ; Trauner, M
Curcumin improves liver injury and biliary fibrosis in MDR2 (ABCB4) knockout mice by inducing anti-oxidative response, but not via modification of bile acid transport/metabolism
J HEPATOL. 2008; 48: S171-S171.-EASL Annual Meeting; April 2008; Milan Italy.
Doi: 10.1016/S0168-8278(08)60450-X
[Poster]
Web of Science
FullText
FullText_MUG
** Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Halilbasic, E; Trauner, MH
LOSS OF FXR ATTENUATES SCLEROSING CHOLANGITIS AND BILIARY FIBROSIS IN MDR2(-/-) AND FXR(-/-) DOUBLE KNOCKOUT MICE
HEPATOLOGY. 2008; 48(4):777--59th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; OCT 31-NOV 04, 2008; San Francisco, CA.
[Poster]
Web of Science
** Moustafa, T; Halilbasic, E; Fickert, P; Fuchsbichler, A; Gumhold, J; Silbert, D; Denk, H; Trauner, M
Side chain modified bile acids modulate endoplasmic reticulum stress in Mdr2(-/-) mice in vivo and bile duct epithelial cells in vitro
J HEPATOL. 2008; 48: S54-S55.-EASL Annula Meeting; April 2008; Milan Italy.
Doi: 10.1016/S0168-8278(08)60127-0
[Oral Communication]
Web of Science
FullText
FullText_MUG
** Sombetzki, M; Fickert, P; Loebermann, M; Holtfreter, M; Fuchsbichler, A; Gumhold, J; Silbert, D; Langner, C; Reisinger, EC; Trauner, M
24-nor-ursodeoxycholic acid as novel therapeutic strategy for inflammation-induced liver fibrosis in a murine model of schistosoma mansoni infection
J HEPATOL. 2008; 48: S21-S22.-Annual Meeting, EASL; April 2008; Mailand, Italien.
Doi: 10.1016/S0168-8278(08)60052-5
[Oral Communication]
Web of Science
FullText
FullText_MUG
2007
Originalarbeit (Zeitschrift)
** Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Gujral, JS; Zatloukal, K; Denk, H; Jaeschke, H; Trauner, M
Hepatobiliary transporter expression in intercellular adhesion molecule 1 knockout and Fas receptor-deficient mice after common bile duct ligation is independent of the degree of inflammation and oxidative stress.
Drug Metab Dispos. 2007; 35(9):1694-1699
Doi: 10.1124/dmd.107.015610
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
** Zollner, G; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Zatloukal, K; Denk, H; Trauner, M
Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis.
Liver Int. 2007; 27(7):920-929
Doi: 10.1111/j.1478-3231.2007.01506.x
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
Abstract (Zeitschrift)
** Halilbasic, E; Fickert, P; Fuchbichler, A; Langner, C; Gumhold, J; Silbert, D; Maitra, U; Zatloukal, K; Denk, H; Trauner, M
Taurine-conjugation critically determines the therapeutic effectiveness of 24-nor-ursodeoxycholic acid (norUDCA) in the treatment of sclerosing cholangitis in Mdr2 (ABCB4) knockout mice
J HEPATOL. 2007; 46: S51-S51.-EASL; April 11-15, 2007;
Doi: 10.1016/S0168-8278(07)61714-0
[Oral Communication]
Web of Science
FullText
FullText_MUG
** Jahnel, J; Wagner, M; Langner, C; Hoegenauer, C; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Denk, H; Trauner, M
Impact of colitis on bile secretion and hepatobiliary transporter expression in mice possible implications for pathogenesis of sclerosing cholangitis
J HEPATOL. 2007; 46: S122-S122.
Doi: 10.1016/S0168-8278(07)61907-2
[Poster]
Web of Science
FullText
FullText_MUG
** Moustafa, T; Fickert, P; Vesely, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Denk, H; Guelly, C; Trauner, M
Retention of toxic bile acids activate the mTOR, p70S6k/rps6 signaling pathway in mouse models of cholestatic liver injury
J HEPATOL. 2007; 46: S23-S23.
Doi: 10.1016/S0168-8278(07)61646-8
[Oral Communication]
Web of Science
FullText
FullText_MUG
** Wagner, M; Moustafa, T; Fickert, P; Zollner, G; Gumhold, J; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M
Absence of FXR protects mice from bile-infarcts in biliary obstruction by reduction of bile acid-independent bile flow: Implications for targeting FXR in treatment of cholestasis?
J HEPATOL. 2007; 46: S5-S5.-42th Annual Meeting, European Association for the Study of the Liver; April, 11-15, 2007; Barcelona, Spain.
Doi: 10.1016/S0168-8278(07)61603-1
[Oral Communication]
Web of Science
FullText
FullText_MUG
** Zollner, G; Caligiuri, A; Fickert, P; Wagner, M; Silbert, D; Pinzani, M; Trauner, M
Expression of bile acid transport and detoxification systems and their regulatory nuclear receptors in human hepatic stellate cells
J HEPATOL. 2007; 46: S135-S135.-42th Annual Meeting, European Association for the Study of the Liver ; April 11-15, 2007; Barcelona, Spain.
Doi: 10.1016/S0168-8278(07)61944-8
[Poster]
Web of Science
FullText
FullText_MUG
2006
Originalarbeit (Zeitschrift)
** Marschall, HU; Wagner, M; Bodin, K; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Sjövall, J; Trauner, M
Fxr(-/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids.
J Lipid Res. 2006; 47(3):582-592
Doi: 10.1194/jlr.M500427-JLR200
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
** Zollner, G; Wagner, M; Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Halilbasic, E; Denk, H; Marschall, HU; Trauner, M
Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids.
Am J Physiol Gastrointest Liver Physiol. 2006; 290(5):G923-G932
Doi: 10.1152/ajpgi.00490.2005
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
Abstract (Zeitschrift)
** Moustafa, T; Fickert, P; Guelly, C; Silbert, D; Gumhold, J; Fuchsbichler, A; Denk, H; Trauner, M
24-nor-ursodeoxycholic acid abolishes enhanced cellular proliferation in Mdr2 (abcb4) knockout mice by modulation of mTOR, p70s6k and rps6 signaling
HEPATOLOGY. 44(4):602A-603A.
[Poster]
Web of Science
** Moustafa, T; Fickert, P; Guelly, C; Silbert, D; Gumhold, J; Fuchsbichler, A; Denk, H; Trauner, M
Transcriptional profiling of Mdr2 knockout (Mdr2-/-) mice treated with nor-UDCA reveals global anti-inflammatory and anti-fibrotic effects
J HEPATOL. 2006; 44: S42-S42.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA.
Doi: 10.1016/S0168-8278(06)80095-4
[Poster]
Web of Science
FullText
FullText_MUG
** Moustafa, T; Fickert, P; Prokesch, A; Wagner, M; Fuchsbichler, A; Silbert, D; Gumhold, J; Denk, H; Trajanoski, Z; Trauner, M
Common bile-duct-ligation of FXR knockout mice results in severe hepatic steatosis due to enhancement in lipogenic gene expression
J HEPATOL. 44: S28-S28.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA.
Doi: 10.1016/S0168-8278(06)80063-2
[Poster]
Web of Science
FullText
FullText_MUG
** Stoger, U; Fickert, P; Fuchsbichler, A; Moustafa, T; Gumhold, J; Silbert, D; Zatlouka, K; Denk, H; Trauner, M
3.5-diethoxycarbonyl-1.4-dihydrocollidine (DDC) feeding induces cholestasis, chronic inflammatory bile duct damage and biliary fibrosis in mice
J HEPATOL. 44: S123-S124.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA.
Doi: 10.1016/S0168-8278(06)80321-1
[Poster]
Web of Science
FullText
FullText_MUG
** Zollner, G; Wagner, M; Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Helmut, D; Marschall, HU; Trauner, M
Role of nuclear bile acid receptor FXR in regulation of bile acid detoxification and organic solute transporter (OST-alpha/beta) expression in bile acid-fed mice
J HEPATOL. 44: S124-S124.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA.
Doi: 10.1016/S0168-8278(06)80322-3
[Poster]
Web of Science
FullText
FullText_MUG
2005
Originalarbeit (Zeitschrift)
** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Diczfalusy, U; Gumhold, J; Silbert, D; Fuchsbichler, A; Benthin, L; Grundström, R; Gustafsson, U; Sahlin, S; Einarsson, C; Trauner, M
Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in humans.
Gastroenterology. 2005; 129(2):476-485
Doi: 10.1016/j.gastro.2005.05.009
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
** Zollner, G; Wagner, M; Fickert, P; Geier, A; Fuchsbichler, A; Silbert, D; Gumhold, J; Zatloukal, K; Kaser, A; Tilg, H; Denk, H; Trauner, M
Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver.
Am J Physiol Gastrointest Liver Physiol. 2005; 289(5):G798-G805
Doi: 10.1152/ajpgi.00319.2004
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
** Zollner, G; Wagner, M; Fickert, P; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M
Hepatobiliary transporter expression in human hepatocellular carcinoma.
Liver Int. 2005; 25(2):367-379
Doi: 10.1111/j.1478-3231.2005.01033.x
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
Abstract (Zeitschrift)
** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundstrom, R; Gustafsson, U; Sahlin, S; Einarsson, C; Trauner, M
Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in human liver
GASTROENTEROLOGY. 2005; 128: A755-A755.
Web of Science
** Marschall, HU; Wagnr, M; Bodin, K; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Sjovall, J; Trauner, M
Fxr -/- mice adapt to obstructive cholestasis by enhanced phase I detoxification and renal elimination of bile acids
J HEPATOL. 2005; 42: 114-115.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
Web of Science
** Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Gujral, J; Zatloukal, K; Jaeschke, H; Deck, H; Trauner, M
Role of inflammation for hepatobiliary transporter expression in ICAM-/- and lpr mice after common bile duct ligation
GASTROENTEROLOGY. 2005; 128: A89-A89.
Web of Science
** Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Gujral, JS; Zatloukal, K; Denk, H; Jaeschke, H; Trauner, M
Alterations of hepatobiliary transporter expression in response to common bile duct ligation in mice are independent of ICAM-1 and FAS-receptor expression
J HEPATOL. 2005; 42: 115-115.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
Web of Science
** Zollner, G; Wagner, M; Fickert, P; Gumhold, J; Silbert, D; Marschall, HU; Denk, H; Trauner, M
Expression of key bile acid detoxification enzymes and the alternative bile acid export pump MRP4 in primary biliary cirrhosis
J HEPATOL. 2005; 42: 240-240.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
Web of Science
** Zollner, G; Wagner, M; Fickert, P; Gumhold, J; Silbert, D; Marschall, HU; Denk, H; Trauner, M
Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis
GASTROENTEROLOGY. 2005; 128: A691-A691.
Web of Science
2004
Abstract (Zeitschrift)
** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundstrom, R; Sahlin, S; Einarsson, C; Trauner, M
Comprehensive study of the effects of rifampicin and ursodeoxycholic acid on genes and proteins involved in regulation, transport and detoxification of biliary compounds in gallstone patients
GASTROENTEROLOGY. 2004; 126: A746-A746.
Web of Science
** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumholdt, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundstrom, R; Sahlin, S; Einarsson, C; Trauner, M
Comprehensive study of the effects of rifampicin and ursodeoxycholic acid on genes and proteins involved in regulation, transport and detoxification of biliary compounds in gallstone patients
J HEPATOL. 2004; 40: 93-93.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(04)90303-0
Web of Science
FullText
FullText_MUG
** Wagner, M; Fickert, P; Marschall, HU; Zollner, G; Silbert, D; Fuchsbichler, A; Gumhold, J; Schuetz, JD; Gonzalez, FJ; Zatloukal, K; Denk, H; Trauner, M
Alternative exretory routes for accumulating bile acids via adaptive renal ABC transporter expression in common bile duct-ligated (CBDL) mice
GASTROENTEROLOGY. 2004; 126: A129-A130.
Web of Science
** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Gu, GL; Marschall, HU; Denk, H; Trauner, M
Role of adaptive hepatobiliary transporter expression and regulation of bile acid synthetic enzymes in MDR2-/- mice: A model for chronic cholestatic liver disease due to sclerosing cholangitis
J HEPATOL. 2004; 40: 163-163.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(04)90557-0
Web of Science
FullText
FullText_MUG
** Wagner, M; Fickert, P; Zollner, G; Silbert, D; Fuchsbichler, A; Gumhold, J; Schuetz, JD; Gonzalez, FJ; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M
Adaptive renal ABC transporter expression in common bile duct-ligated mice
J HEPATOL. 2004; 40: 26-26.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(04)90073-6
Web of Science
FullText
FullText_MUG
** Wagner, M; Fickert, P; Zollner, G; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M
Gender and pregnancy affect hepatic and renal ABC transporter expression in mice
J HEPATOL. 2004; 40: 94-94.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(04)90307-8
Web of Science
FullText
FullText_MUG
** Wagner, M; Fickert, P; Zollner, G; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M
Hepatic and renal ABC transporter expression in mice depends on gender and changes in pregnancy
GASTROENTEROLOGY. 2004; 126: A130-A130.
Web of Science
** Wagner, M; Halilbasic, E; Fickert, P; Zollner, G; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Denk, H; Trauner, M
Nuclear receptor (PXR, CAR) agonists induce adaptive hepatic transporter and enzyme expression in mouse liver
J HEPATOL. 2004; 40: 25-25.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
Doi: 10.1016/S0168-8278(04)90069-4
Web of Science
FullText
FullText_MUG
** Wagner, M; Halilbasic, E; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M
Xenobiotic nuclear receptor (PXR, CAR) agonists coordinately stimulate a spectrum of detoxification enzymes and transport systems involved in the adaptive response to cholestasis in vivo.
HEPATOLOGY. 2004; 40: 489A-489A.-55th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); OCT 29-NOV 02, 2004; Boston, MA.
Web of Science
** Zollner, G; Halilbasic, E; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M
Cholic acid (CA) and ursodeoxycholic acid (UDCA) exert different effects on hepatic and renal expression of Mrp4 and Mrp6, two novel ABC transporters
GASTROENTEROLOGY. 2004; 126: A16-A16.
Web of Science
** Zollner, G; Halilbasic, E; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M
Differential effects of ursodeoxycholic acid (UDCA) and cholic acid (CA) on hepatic and renal expression of MRP4 and MRP6, two novel abc transporters, in mice
J HEPATOL. 2004; 40: 25-25.
Doi: 10.1016/S0168-8278(04)90070-0
Web of Science
FullText
FullText_MUG
** Zollner, G; Wagner, M; Fickert, P; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Guo, GL; Marschall, HU; Denk, H; Trauner, M
Mdr2(-/-) mice with sclerosing cholangitis: A model of chronic cholestasis to study the role of the adaptive response of hepatobiliary transport systems and bile acid synthetic enzymes
GASTROENTEROLOGY. 2004; 126: A751-A751.
Web of Science
2003
Originalarbeit (Zeitschrift)
** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Silbert, D; Tsybrovskyy, O; Zatloukal, K; Guo, GL; Schuetz, JD; Gonzalez, FJ; Marschall, HU; Denk, H; Trauner, M
Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice.
Gastroenterology. 2003; 125(3):825-838
Doi: 10.1016/S0016-5085(03)01068-0
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
** Zollner, G; Fickert, P; Fuchsbichler, A; Silbert, D; Wagner, M; Arbeiter, S; Gonzalez, FJ; Marschall, HU; Zatloukal, K; Denk, H; Trauner, M
Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine.
J Hepatol. 2003; 39(4):480-488
Doi: 10.1016/S0168-8278(03)00228-9
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Marschall, HU; Zatloukal, K; Denk, H; Trauner, M
Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis.
J Hepatol. 2003; 38(6):717-727
Doi: 10.1016/S0168-8278(03)00096-5
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
Abstract (Zeitschrift)
** Wagner, M; Fickert, P; Fuchsbichler, A; Silbert, D; Gumhold, J; Zollner, G; Zatloukal, K; Marschall, HU; Schuetz, JD; Gonzalez, FJ; Denk, H; Trauner, M
Hepatic and renal ABC transporter expression as critical determinants of ursodeoxycholic acid-induced bile infarcts in bile duct-ligated mice.
HEPATOLOGY 2003 38: 688A-689A.
Web of Science
** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Silbert, D; Marschall, HU; Gonzalez, FJ; Zatloukal, K; Denk, H; Trauner, M
The role of the bile acid receptor FXR in determining ATP-binding cassette (ABC) transporter expression and liver injury in common bile duct ligated (CBDL) mice
J HEPATOL 2003 38: 190-190.
Doi: 10.1016/S0168-8278(03)80031-4
Web of Science
FullText
FullText_MUG
** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Silbert, D; Tsybrovskyy, O; Gonzalez, FJ; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M
Role of nuclear bile acid receptor, FXR, in determining ATP-binding cassette (ABC) transporter expression and cholestatic liver injury in common bile duct-ligated mice
GASTROENTEROLOGY 2003 124: A697-A698.
Doi: 10.1016/S0016-5085(03)83527-8
Web of Science
FullText
FullText_MUG
** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Wagner, M; Guo, G; Gonzalez, FJ; Zatloukal, K; Denk, H; Trauner, M
Role of nuclear bile salt receptors Fxr and Pxr in mediating adaptive hepatobiliary transporter response to cholic acid (CA) in mouse liver
GASTROENTEROLOGY 2003 124: A59-A59.
Doi: 10.1016/S0016-5085(03)80292-5
Web of Science
FullText
FullText_MUG
** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Wagner, M; Zatloukal, K; Denk, H; Trauner, M
Regulation of the Na+/taurocholate cotransporter Ntcp via short heterodimer partner (SHP)-dependent or SHP-independent mechanims depends on the type of cholestatic injury
GASTROENTEROLOGY 2003 124: A730-A730.
Doi: 10.1016/S0016-5085(03)83688-0
Web of Science
FullText
FullText_MUG
** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Wagner, M; Zatloukal, K; Denk, H; Trauner, M
Role of short heterodimer partner (SHP) -dependent and -independent pathways for regulation of Na+/taurocholate cotransporter (NTCP) expression in cholestatic mouse models.
J HEPATOL. 2003; 38(2):9-10.-38th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; MAR 29-APR 01, 2003; ISTANBUL, TURKEY.
Doi: 10.1016/S0168-8278(03)80442-7
Web of Science
PubMed
FullText
FullText_MUG
** Zollner, G; Fickert, P; Wagner, M; Fuchsbichler, A; Silbert, D; Gumhold, J; Zatloukal, K; Denk, H; Trauner, M
Induction of intestinal multidrug resistance-associated proteins 2 and 3 (Mrp2, Mrp3) by cholic acid (CA) and ursodeoxycholic acid (UDCA) in mice.
HEPATOLOGY 2003 38: 689A-689A.
Web of Science
2002
Originalarbeit (Zeitschrift)
** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Stumptner, C; Zatloukal, K; Denk, H; Trauner, M
Induction of short heterodimer partner 1 precedes downregulation of Ntcp in bile duct-ligated mice.
Am J Physiol Gastrointest Liver Physiol. 2002; 282(1):G184-G191
Doi: 10.1152/ajpgi.00215.2001
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
Abstract (Zeitschrift)
** Fickert, P; Zollner, G; Silbert, D; Fuchsbichler, A; Arbeiter, S; Gonzalez, F; Denk, H; Trauner, M
Adaptive hepatic and renal transporter regulation in cholic acid (CA)-fed mice: Role of nuclear bile acid receptor (FXR).
HEPATOLOGY 2002 36: 454A-454A.
Web of Science
** Zollner, G; Fickert, P; Arbeiter, S; Silbert, D; Fuchsbichler, A; Gonzalez, F; Zatloukal, K; Denk, H; Trauner, M
Ursodeoxycholic acid (UDCA) feeding induces adaptive hepatic and renal ABC-transporter expression in mice.
HEPATOLOGY 2002 36: 454A-454A.
Web of Science
** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Stumptner, C; Neuberger, J; Zatloukal, K; Denk, H; Trauner, M
Alterations of hepatobiliary transporter expression in primary biliary cirrhosis (PBC)
J HEPATOL 2002 36: 28-29.
Doi: 10.1016/S0168-8278(02)80086-1
Web of Science
FullText
FullText_MUG
** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M
Messenger RNA expression of nuclear, orphan receptors and hepatocyte nuclear factor 1 alpha (HNF-1 alpha) in inflammation-associated cholestasis (IC) and primary biliary cirrhosis
HEPATOLOGY 2002 36: 454A-454A.
Web of Science
2001
Abstract (Zeitschrift)
** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Stumptner, C; Ott, P; Zatloukal, K; Denk, H; Trauner, M
Expression of multidrug resistance p-glycoproteins (MDR), multidrug resistance-associated proteins (MRP) and bile acid transporters in human hepatocellular carcinomas (HCC).
HEPATOLOGY 2001 34: 665A-665A.
Web of Science
** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M; Franzens, K
Induction of the transcriptional repressor short heterodimer partner 1 precedes down-regulation of the Na+/taurocholate cotransporter in bile duct-ligated mice.
HEPATOLOGY 2001 34: 469A-469A.
Web of Science