Medizinische Universität Graz - Research portal
Pfragner Roswitha |
** = Publications listed in SCI/SSCI/Pubmed
2022
Full paper/article (Journal)
** Pfanzagl, B; Pfragner, R; Jensen-Jarolim, E
Histamine via histamine H1 receptor enhances the muscarinic receptor-induced calcium response to acetylcholine in an enterochromaffin cell model
CLIN EXP PHARMACOL P. 2022;
Doi: 10.1111/1440-1681.13682
[OPEN ACCESS]
Web of Science
PubMed
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2021
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** Laskaratos, FM; Levi, A; Schwach, G; Pfragner, R; Hall, A; Xia, D; von Stempel, C; Bretherton, J; Thanapirom, K; Alexander, S; Ogunbiyi, O; Watkins, J; Luong, TV; Toumpanakis, C; Mandair, D; Caplin, M; Rombouts, K
Transcriptomic Profiling of In Vitro Tumor-Stromal Cell Paracrine Crosstalk Identifies Involvement of the Integrin Signaling Pathway in the Pathogenesis of Mesenteric Fibrosis in Human Small Intestinal Neuroendocrine Neoplasms.
Front Oncol. 2021; 11(6):629665-629665
Doi: 10.3389/fonc.2021.629665
[OPEN ACCESS]
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2019
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** Ghaffari-Tabrizi-Wizsy, N; Passegger, CA; Nebel, L; Krismer, F; Herzer-Schneidhofer, G; Schwach, G; Pfragner, R
The avian chorioallantoic membrane as an alternative tool to study medullary thyroid cancer.
Endocr Connect. 2019; 8(5):462-467
Doi: 10.1530/EC-18-0431
[OPEN ACCESS]
Web of Science
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** Pfanzagl, B; Pfragner, R; Jensen-Jarolim, E
The Transient Receptor Potential Vanilloid 4 Agonist RN-1747 Inhibits the Calcium Response to Histamine.
Pharmacology. 2019; 104(3-4): 166-172.
Doi: 10.1159/000501144
Web of Science
PubMed
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** Pfanzagl, B; Zevallos, VF; Schuppan, D; Pfragner, R; Jensen-Jarolim, E
Histamine causes influx via T-type voltage-gated calcium channels in an enterochromaffin tumor cell line: potential therapeutic target in adverse food reactions.
Am J Physiol Gastrointest Liver Physiol. 2019; 316(2): G291-G303.
Doi: 10.1152/ajpgi.00261.2018
[OPEN ACCESS]
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2018
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** Alvarez, MJ; Subramaniam, PS; Tang, LH; Grunn, A; Aburi, M; Rieckhof, G; Komissarova, EV; Hagan, EA; Bodei, L; Clemons, PA; Dela Cruz, FS; Dhall, D; Diolaiti, D; Fraker, DA; Ghavami, A; Kaemmerer, D; Karan, C; Kidd, M; Kim, KM; Kim, HC; Kunju, LP; Langel, U; Li, Z; Lee, J; Li, H; LiVolsi, V; Pfragner, R; Schwach, G; Rainey, AR; Realubit, RB; Remotti, H; Regberg, J; Roses, R; Rustgi, A; Sepulveda, AR; Serra, S; Shi, CJ; Yuan, XP; Barberis, M; Bergamaschi, R; Chinnaiyan, AM; Detre, T; Ezzat, S; Frilling, A; Hommann, M; Jaeger, D; Kim, MK; Knudsen, BS; Kung, AL; Leahy, E; Metz, DC; Milsom, JW; Park, YS; Reidy-Lagunes, D; Schreiber, S; Washington, K; Wiedenmann, B; Modlin, I; Califano, A
A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors.
Nat Genet. 2018; 50(7):979-989
Doi: 10.1038/s41588-018-0138-4
[OPEN ACCESS]
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** Hofving, T; Arvidsson, Y; Almobarak, B; Inge, L; Pfragner, R; Persson, M; Stenman, G; Kristiansson, E; Johanson, V; Nilsson, O
The neuroendocrine phenotype, genomic profile and therapeutic sensitivity of GEPNET cell lines.
ENDOCR-RELAT CANCER. 2018; 25(3): 367-380.
Doi: 10.1530/ERC-17-0445
[OPEN ACCESS]
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Correction
** Hofving, T; Arvidsson, Y; Almobarak, B; Inge, L; Pfragner, R; Persson, M; Stenman, G; Kristiansson, E; Johanson, V; Nilsson, O
The neuroendocrine phenotype, genomic profile and therapeutic sensitivity of GEPNET cell lines.
Endocr Relat Cancer. 2018; 25(4):X1-X2
Doi: 10.1530/ERC-17-0445e
[OPEN ACCESS]
Web of Science
PubMed
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Abstract (Journal)
** Alvarez, MJ; Bosker, G; Pfragner, R; Kidd, M; Modlin, I; Califano, A.
Systematic, network-based, comparative analysis of differential mechanisms of action of lanreotide and octreotide in neuroendocrine tumor derived cell lines.
CANCER RES. 2018; 78(13):-Annual Meeting of the American-Association-for-Cancer-Research (AACR); APR 14-18, 2018; Chicago, IL.
Doi: 10.1158/1538-7445.AM2018-LB-061
[Oral Communication]
Web of Science
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** Hofving, T; Arvidsson, Y; Almobarak, B; Inge, L; Pfragner, R; Persson, M; Stenman, G; Johanson, V; Nilsson, O
The Neuroendocrine Phenotype, Genomic Profile, and Therapeutic Sensitivity of GEPNET Cell Lines
NEUROENDOCRINOLOGY. 2018; 106: 48-48.-15th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease; MAR 07-09, 2018; Barcelona, SPAIN.
[Oral Communication]
Web of Science
2017
Full paper/article (Journal)
** Hasenoehrl, C; Schwach, G; Ghaffari-Tabrizi-Wizsy, N; Fuchs, R; Kretschmer, N; Bauer, R; Pfragner, R
Anti-tumor effects of shikonin derivatives on human medullary thyroid carcinoma cells.
Endocr Connect. 2017; 6(2):53-62
Doi: 10.1530/EC-16-0105
[OPEN ACCESS]
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** Pfanzagl, B; Mechtcheriakova, D; Meshcheryakova, A; Aberle, SW; Pfragner, R; Jensen-Jarolim, E
Activation of the ileal neuroendocrine tumor cell line P-STS by acetylcholine is amplified by histamine: role of H3R and H4R.
Sci Rep. 2017; 7(1):1313-1313
Doi: 10.1038/s41598-017-01453-5
[OPEN ACCESS]
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** Tatzber, F; Pursch, E; Resch, U; Pfragner, R; Holasek, S; Lindschinger, M; Cvirn, G; Wonisch, W
Cultivation and Immortalization of Human B-Cells Producing a Human Monoclonal IgM Antibody Binding to MDA-LDL: Further Evidence for Formation of Atherogenic MDA-LDL Adducts in Humans In Vivo
OXID MED CELL LONGEV. 2017; 6047142
Doi: 10.1155/2017/6047142
[OPEN ACCESS]
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Abstract (Journal)
** Frampton, AE; Miller, HC; Malczewska, A; Ottaviani, S; Stronach, EA; Flora, R; Kaemmerer, D; Schwach, G; Pfragner, R; Faiz, O; Kos-Kudla, B; Hanna, GB; Stebbing, J; Castellano, L; Frilling, A.
MicroRNAs Associated with Small Bowel Neuroendocrine Tumours and Their Metastases.
NEUROENDOCRINOLOGY. .. 2017; 105: 22-22.-14th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease.; MAR 08-10, 2017; Barcelona, SPAIN..
[Oral Communication]
Web of Science
2016
Full paper/article (Journal)
** Arvidsson, Y; Johanson, V; Pfragner, R; Wängberg, B; Nilsson, O
Cytotoxic Effects of Valproic Acid on Neuroendocrine Tumour Cells.
Neuroendocrinology. 2016; 103(5):578-591
Doi: 10.1159/000441849
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** Miller, HC; Frampton, AE; Malczewska, A; Ottaviani, S; Stronach, EA; Flora, R; Kaemmerer, D; Schwach, G; Pfragner, R; Faiz, O; Kos-Kudła, B; Hanna, GB; Stebbing, J; Castellano, L; Frilling, A
MicroRNAs associated with small bowel neuroendocrine tumours and their metastases.
Endocr Relat Cancer. 2016; 23(9):711-726
Doi: 10.1530/ERC-16-0044
[OPEN ACCESS]
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Abstract (Journal)
** Errampalli, R; Reicher, A; Kleinegger, F; Hirschnock, T; Pfragner, R; Schwach, G; Schicho, R; Tabrizi-Wizsy, NG
Cannabinoids as Inhibitor of Tumour Growth and Invasiveness in Small Intestine Neuroendocrine Cancer
NEUROENDOCRINOLOGY. 2016; 103: 11-11.-13th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease; MAR 09-11, 2016; Barcelona, SPAIN.
[Poster]
Web of Science
** Pfragner, R; Schwach, G; Tabrizi-Wizsy, NG; Hoeger, H; Tam-Amersdorfer, C; Leitinger, G; Bock, E; Nebral, K; Zeitlhofer, P; Haas, OA; Niederle, B; Strobl, H
Establishment and Characterization of a Continuous Cell Line from a Human Familial Medullary Thyroid Carcinoma
NEUROENDOCRINOLOGY. 2016; 103: 117-118.-13th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease; MAR 09-11, 2016; Barcelona, SPAIN.
[Poster]
Web of Science
** Schwach, G; Wizsy, NGT; Tam-Amersdorfer, C; Meier-Allard, N; Siddiqui, ZG; Hoeger, H; Haas, OA; Speicher, M; Niederle, B; Pfragner, R
Medullary Thyroid Carcinoma Cell Lines - An Update
NEUROENDOCRINOLOGY. 2016; 103: 13-13.
[Poster]
Web of Science
2015
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** Aguiriano-Moser, V; Svejda, B; Li, ZX; Sturm, S; Stuppner, H; Ingolic, E; Höger, H; Siegl, V; Meier-Allard, N; Sadjak, A; Pfragner, R
Ursolic acid from Trailliaedoxa gracilis induces apoptosis in medullary thyroid carcinoma cells.
Mol Med Rep. 2015; 12(4):5003-5011
Doi: 10.3892/mmr.2015.4053
[OPEN ACCESS]
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** Fuchs, R; Schwach, G; Stracke, A; Meier-Allard, N; Absenger, M; Ingolic, E; Haas, HS; Pfragner, R; Sadjak, A
The anti-hypertensive drug prazosin induces apoptosis in the medullary thyroid carcinoma cell line TT.
Anticancer Res. 2015; 35(1):31-38
[OPEN ACCESS]
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** Pozo, K; Hillmann, A; Augustyn, A; Plattner, F; Hai, T; Singh, T; Ramezani, S; Sun, X; Pfragner, R; Minna, JD; Cote, GJ; Chen, H; Bibb, JA; Nwariaku, FE
Differential expression of cell cycle regulators in CDK5-dependent medullary thyroid carcinoma tumorigenesis.
Oncotarget. 2015; 6(14):12080-12093
Doi: 10.18632/oncotarget.3813
[OPEN ACCESS]
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** Zanini, S; Giovinazzo, F; Alaimo, D; Lawrence, B; Pfragner, R; Bassi, C; Modlin, I; Kidd, M
GNA15 expression in small intestinal neuroendocrine neoplasia: functional and signalling pathway analyses.
Cell Signal. 2015; 27(5):899-907
Doi: 10.1016/j.cellsig.2015.02.001
Web of Science
PubMed
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Abstract (Journal)
** Kleinegger, F; Meier-Allard, N; Fuchs, R; Holzl, M; Krump, C; Passegger, C; Pfragner, R; Tabrizi-Wizsy, NG
Cancer Stem Cells in Small Intestine Neuroendocrine Cell Line P-STS: Isolation and Molecular Characterisation.
NEUROENDOCRINOLOGY. 2015; 102(1-2):89-89.-12th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease; MAR 11-13, 2015; Barcelona, SPAIN.
[Poster]
Web of Science
** Passegger, C; Kump, P; Hayback, J; Lipp, R; Niederle, B; Pfragner, R; Sadjak, A; Schwach, G; Spindelbock, W; Tabrizi-Wizsy, NG
The Chicken Chorioallantoic Membrane Assay as a Preclinical Model for the Research of Rare Gastrointenstinal Neuroendocrine Tumours.
NEUROENDOCRINOLOGY. 2015; 102(1-2):160-160.-12th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease; MAR 11-13, 2015; Barcelona, SPAIN.
[Poster]
Web of Science
** Pfragner, R; Schwach, G; Hoeger, H; Tabrizi-Wizsy, NG; Tam-Amersdorfer, C; Leitinger, G; Bock, E; Zeitlhofer, P; Haas, OA; Beichler, C; Speicher, MR; Rinner, B; Niederle, B; Strobl, H
A Novel Human Cell Line from Familial Medullary Thyroid Carcinoma
NEUROENDOCRINOLOGY. 2015; 102(1-2):86-86.-12th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease; MAR 11-13, 2015; Barcelona, SPAIN.
[Poster]
Web of Science
** Schwach, G; Pfragner, R; Hoeger, H; Schoefberger, W; Wilfert, S; Brueggemann, O; Teasdale, I
Epirubicin Loaded Polyphosphazene; A New Agent against Small Intestinal Neuroendocrine Tumors and Medullary Thyroid Carcinomas.
NEUROENDOCRINOLOGY. 2015; 102(1-2):161-161.-12th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease; MAR 11-13, 2015; Barcelona, SPAIN.
[Poster]
Web of Science
2014
Abstract (Journal)
** Ghaffari-Tabrizi-Wizsy, N; Holzl, M; Fuchs, R; Krump, C; Pfragner, R; Kleinegger, F
Cancer stem cells in small intenstine neuroendocrine cell line P-STS: Isolation and characterisation.
WIEN KLIN WOCHENSCHR. 2014; 126: S154-S154.
[Poster]
Web of Science
** Ghaffari-Tabrizi-Wizsy; N; Passegger, CA; Kleinegger, F; Schwach, G; Schweighofer, B; Genze, F; Sadjak, A; Pfragner, R
The chick embryo chorioallantoic membrane as a tool to study medullary thyroid cancer
WIEN KLIN WOCHENSCHR. 2014; 126: S154-S154.-14th International workshop on multiple endocrine neoplasia and other rare endocrine tumors; SEP 25-27,2014; Vienna, AUSTRIA.
[Poster]
Web of Science
** Haas, HS; Rohrer, K; Tabrizi-Wizsy, NG; Pfragner, R; Schwach, G; Schwarzenberger, E; Tam-Amersdorfer, C; Allard, N; Albrecher, N; Horwath, C; Sadjak, A
Metabotropic glutamate receptor-1 (mGluR1) antagonists as targets for the treatment of neuroendocrine tumors
WIEN KLIN WOCHENSCHR. 2014; 126: S159-S159.
[Poster]
Web of Science
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** Schwach, G; Pfragner, R; Schoefberger, W; Wilfert, S; Bruggemann, O; Teasdale, I
Polyphosphazene-a new drug-delivery agent; epirubicin loaded polyphosphazenes show antitumor activity in small intestinal neuroendocrine tumor and medullary thyroid carcinoma cell lines
WIEN KLIN WOCHENSCHR. 2014; 126: S162-S162.-International Workshop on Multiple Endocrine Neoplasia and other rare endocrine tumors; SEP 25-27,2014;; SEP 25-27,2014; Vienna, AUSTRIA.
[Poster]
Web of Science
2013
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** Dammen, R; Damen, R; Haugen, M; Svejda, B; Alaimo, D; Brenna, O; Pfragner, R; Gustafsson, BI; Kidd, M
The stimulatory adenosine receptor ADORA2B regulates serotonin (5-HT) synthesis and release in oxygen-depleted EC cells in inflammatory bowel disease.
PLoS One. 2013; 8(4):e62607-e62607
Doi: 10.1371/journal.pone.0062607
[OPEN ACCESS]
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** Giovinazzo, F; Schimmack, S; Svejda, B; Alaimo, D; Pfragner, R; Modlin, I; Kidd, M
Chromogranin A and its fragments as regulators of small intestinal neuroendocrine neoplasm proliferation.
PLoS One. 2013; 8(11):e81111-e81111
Doi: 10.1371/journal.pone.0081111
[OPEN ACCESS]
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** Haas, HS; Pfragner, R; Tabrizi-Wizsy, NG; Rohrer, K; Lueftenegger, I; Horwath, C; Allard, N; Rinner, B; Sadjak, A
The influence of glutamate receptors on proliferation and metabolic cell activity of neuroendocrine tumors.
Anticancer Res. 2013; 33(4): 1267-1272.
Web of Science
PubMed
** Hofer, D; Schwach, G; Ghaffari Tabrizi-Wizsy, N; Sadjak, A; Sturm, S; Stuppner, H; Pfragner, R
Christia vespertilionis plant extracts as novel antiproliferative agent against human neuroendocrine tumor cells.
Oncol Rep. 2013; 29(6):2219-2226
Doi: 10.3892/or.2013.2367
[OPEN ACCESS]
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** Pozo, K; Castro-Rivera, E; Tan, C; Plattner, F; Schwach, G; Siegl, V; Meyer, D; Guo, A; Gundara, J; Mettlach, G; Richer, E; Guevara, JA; Ning, L; Gupta, A; Hao, G; Tsai, LH; Sun, X; Antich, P; Sidhu, S; Robinson, BG; Chen, H; Nwariaku, FE; Pfragner, R; Richardson, JA; Bibb, JA
The role of Cdk5 in neuroendocrine thyroid cancer.
Cancer Cell. 2013; 24(4):499-511
Doi: 10.1016/j.ccr.2013.08.027
[OPEN ACCESS]
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PubMed
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** Svejda, B; Kidd, M; Timberlake, A; Harry, K; Kazberouk, A; Schimmack, S; Lawrence, B; Pfragner, R; Modlin, IM
Serotonin and the 5-HT7 receptor: the link between hepatocytes, IGF-1 and small intestinal neuroendocrine tumors.
Cancer Sci. 2013; 104(7):844-855
Doi: 10.1111/cas.12174
[OPEN ACCESS]
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2012
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** Chin, A; Svejda, B; Gustafsson, BI; Granlund, AB; Sandvik, AK; Timberlake, A; Sumpio, B; Pfragner, R; Modlin, IM; Kidd, M
The role of mechanical forces and adenosine in the regulation of intestinal enterochromaffin cell serotonin secretion.
AM J PHYSIOL-GASTR L. 2012; 302(3): G397-G405.
Doi: 10.1152/ajpgi.00087.2011
[OPEN ACCESS]
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** Flicker, K; Ulz, P; Höger, H; Zeitlhofer, P; Haas, OA; Behmel, A; Buchinger, W; Scheuba, C; Niederle, B; Pfragner, R; Speicher, MR
High-resolution analysis of alterations in medullary thyroid carcinoma genomes.
Int J Cancer. 2012; 131(2):E66-E73
Doi: 10.1002/ijc.26494
[OPEN ACCESS]
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** Haugen, M; Dammen, R; Svejda, B; Gustafsson, BI; Pfragner, R; Modlin, I; Kidd, M
Differential signal pathway activation and 5-HT function: the role of gut enterochromaffin cells as oxygen sensors.
AMER J PHYSIOL-GASTROINTEST L. 2012; 303(10): G1164-G1173.
Doi: 10.1152/ajpgi.00027.2012
[OPEN ACCESS]
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PubMed
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** Kalhan, A; Gharibi, B; Vazquez, M; Jasani, B; Neal, J; Kidd, M; Modlin, IM; Pfragner, R; Rees, DA; Ham, J
Adenosine A2A and A2B receptor expression in neuroendocrine tumours: potential targets for therapy.
Purinergic Signal. 2012; 8(2):265-274
Doi: 10.1007/s11302-011-9280-5
[OPEN ACCESS]
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** Rinner, B; Gallè, B; Trajanoski, S; Fischer, C; Hatz, M; Maierhofer, T; Michelitsch, G; Moinfar, F; Stelzer, I; Pfragner, R; Guelly, C
Molecular evidence for the bi-clonal origin of neuroendocrine tumor derived metastases.
BMC Genomics. 2012; 13(6):594-594
Doi: 10.1186/1471-2164-13-594
[OPEN ACCESS]
Web of Science
PubMed
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** Rokstad, AM; Gustafsson, BI; Espevik, T; Bakke, I; Pfragner, R; Svejda, B; Modlin, IM; Kidd, M
Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies.
Cancer Sci. 2012; 103(7):1230-1237
Doi: 10.1111/j.1349-7006.2012.02282.x
[OPEN ACCESS]
Web of Science
PubMed
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** Schwach, G; Thamyongkit, P; Reith, LM; Svejda, B; Knör, G; Pfragner, R; Schoefberger, W
A water soluble tri-cationic porphyrin-EDTA conjugate induces apoptosis in human neuroendocrine tumor cell lines.
Bioorg Chem. 2012; 40(1): 108-113.
Doi: 10.1016/j.bioorg.2011.09.006
[OPEN ACCESS]
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2011
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** Drozdov, I; Svejda, B; Gustafsson, BI; Mane, S; Pfragner, R; Kidd, M; Modlin, IM
Gene network inference and biochemical assessment delineates GPCR pathways and CREB targets in small intestinal neuroendocrine neoplasia.
PLoS One. 2011; 6(8):e22457-e22457
Doi: 10.1371/journal.pone.0022457
[OPEN ACCESS]
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** Svejda, B; Kidd, M; Kazberouk, A; Lawrence, B; Pfragner, R; Modlin, IM
Limitations in small intestinal neuroendocrine tumor therapy by mTor kinase inhibition reflect growth factor-mediated PI3K feedback loop activation via ERK1/2 and AKT.
CANCER-AM CANCER SOC. 2011; 117(18): 4141-4154.
Doi: 10.1002/cncr.26011
[OPEN ACCESS]
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Abstract (Journal)
** Drozdov, I; Kidd, M; Svejda, B; Gustafsson, B; Mane, S; Pfragner, R; Modlin, I
Utilization of Gene Network Graph Topology with Inference Relevance Analysis Delineates G Protein-Coupled Receptor Pathways and CREB Targets in Small Intestinal Neuroendocrine Neoplasia
NEUROENDOCRINOLOGY. 2011; 94: 3-3.
[Poster]
Web of Science
** Kidd, M; Lawrence, B; Alaimo, D; Svejda, B; Schimmack, S; Singh, D; Pfragner, R; Modlin, I
Evidence for the Role of miR196a in Regulating Small Intestinal Neuroendocrine Tumor Proliferation and Metastasis via HOX/AKT Pathway Activation
NEUROENDOCRINOLOGY. 2011; 94: 6-6.
[Poster]
Web of Science
** Lawrence, B; Kidd, M; Alaimo, D; Svejda, B; Drozdov, I; Schimmack, S; Pfragner, R; Modlin, I
Cell Cycle Phase Expression Profile Guided Selection of Proliferative Markers for Well-Differentiated Small Intestinal Neuroendocrine Neoplasms
NEUROENDOCRINOLOGY. 2011; 94: 7-7.
[Oral Communication]
Web of Science
** Svejda, B; Kidd, M; Lawrence, B; Alaimo, D; Schimmack, S; Pfragner, R; Modlin, I
Hepatic Neuroendocrine Tumor Metastasis Proliferation Is Hepatocyte Regulated via a 5HT7 Mediated Induction of an IGF 1 and HGF Feedback Loop Mediated by cAMP, PKA-Independent pAKT and pCREB
NEUROENDOCRINOLOGY. 2011; 94: 12-12.
[Poster]
Web of Science
2010
Full paper/article (Journal)
** Haas, HS; Linecker, A; Pfragner, R; Sadjak, A
Peripheral glutamate signaling in head and neck areas.
Head Neck. 2010; 32(11): 1554-1572.
Doi: 10.1002/hed.21438
Web of Science
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** Haeubl, M; Schuerz, S; Svejda, B; Reith, LM; Gruber, B; Pfragner, R; Schoefberger, W
Asymmetrically substituted cationic indole- and fluorene porphyrins inhibit tumor proliferation in small intestinal neuroendocrine tumors and medullary thyroid carcinomas.
Eur J Med Chem. 2010; 45(2): 760-773.
Doi: 10.1016/j.ejmech.2009.11.025
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** Schwach, G; Tschemmernegg, M; Pfragner, R; Ingolic, E; Schreiner, E; Windisch, M
Establishment of stably transfected rat neuronal cell lines expressing alpha-synuclein GFP fusion proteins.
J Mol Neurosci. 2010; 41(1): 80-88.
Doi: 10.1007/s12031-009-9289-1
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** Svejda, B; Aguiriano-Moser, V; Sturm, S; Höger, H; Ingolic, E; Siegl, V; Stuppner, H; Pfragner, R
Anticancer activity of novel plant extracts from Trailliaedoxa gracilis (W. W. Smith and Forrest) in human carcinoid KRJ-I Cells.
Anticancer Res. 2010; 30(1):55-64
Web of Science
PubMed
** Svejda, B; Kidd, M; Giovinazzo, F; Eltawil, K; Gustafsson, BI; Pfragner, R; Modlin, IM
The 5-HT2B Receptor Plays a Key Regulatory Role in Both Neuroendocrine Tumor Cell Proliferation and the Modulation of the Fibroblast Component of the Neoplastic Microenvironment
CANCER. 2010; 116(12): 2902-2912.
Doi: 10.1002/cncr.25049
[OPEN ACCESS]
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** Yao, L; Barontini, M; Niederle, B; Jech, M; Pfragner, R; Dahia, PL
Mutations of the Metabolic Genes IDH1, IDH2, and SDHAF2 Are Not Major Determinants of the Pseudohypoxic Phenotype of Sporadic Pheochromocytomas and Paragangliomas.
J Clin Endocrinol Metab. 2010; 95(3): 1469-1472.
Doi: 10.1210/jc.2009-2245
[OPEN ACCESS]
Web of Science
PubMed
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Abstract (Journal)
** Kidd, M; Giovinazzo, F; Svejda, B; Solligard, E; Pfragner, R; Modlin, IM
Chromogranin A fragments, vasostatin and chromostatin, are regulatory peptides that control small intestinal neuroendocrine tumour proliferation via AKT/mTOR signalling
REGUL PEPTIDES. 2010; 164(1):29-29.-Regulation of Petides;
Doi: 10.1016/j.regpep.2010.07.065
[Oral Communication]
Web of Science
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** Kidd, M; Kazberouk, A; Giovinazza, F; Timberlake, A; Pfragner, R; Modlin, IM
Intestinal serotonin (5-HT) signalling is hormonally regulated via glucagon-like peptide 1 (GLP1) and PKA/MAPK activation
REGUL PEPTIDES. 2010; 164(1):37-38.-Regulation of Petides;
Doi: 10.1016/j.regpep.2010.07.093
[Oral Communication]
Web of Science
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** Kidd, M; Svejda, B; Pfragner, R; Modlin, IM
Serotonin is a critical signalling molecule in the local and metastatic small intestinal neuroendocrine tumour microenvironment
REGUL PEPTIDES. 2010; 164(1):38-38.-Regulation of Peptides;
Doi: 10.1016/j.regpep.2010.07.094
[Oral Communication]
Web of Science
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2009
Full paper/article (Journal)
** Bachleitner-Hofmann, T; Friedl, J; Hassler, M; Hayden, H; Dubsky, P; Sachet, M; Rieder, E; Pfragner, R; Brostjan, C; Riss, S; Niederle, B; Gnant, M; Stift, A
Pilot trial of autologous dendritic cells loaded with tumor lysate(s) from allogeneic tumor cell lines in patients with metastatic medullary thyroid carcinoma.
ONCOL REP. 2009; 21(6): 1585-1592.
Doi: 10.3892/or_00000391
[OPEN ACCESS]
Web of Science
PubMed
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** Drozdov, I; Kidd, M; Gustafsson, BI; Svejda, B; Joseph, R; Pfragner, R; Modlin, IM
Autoregulatory effects of serotonin on proliferation and signaling pathways in lung and small intestine neuroendocrine tumor cell lines.
Cancer. 2009; 115(21): 4934-4945.
Doi: 10.1002/cncr.24533
[OPEN ACCESS]
Web of Science
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** Modlin, IM; Gustafsson, BI; Drozdov, I; Nadler, B; Pfragner, R; Kidd, M
Principal Component Analysis, Hierarchical Clustering, and Decision Tree Assessment of Plasma mRNA and Hormone Levels as an Early Detection Strategy for Small Intestinal Neuroendocrine (Carcinoid) Tumors
ANNALS SURG ONCOLOGY. 2009; 16(2): 487-498.
Doi: 10.1245/s10434-008-0251-1
Web of Science
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** Pfragner, R; Behmel, A; Höger, H; Beham, A; Ingolic, E; Stelzer, I; Svejda, B; Moser, VA; Obenauf, AC; Siegl, V; Haas, O; Niederle, B
Establishment and characterization of three novel cell lines - P-STS, L-STS, H-STS - derived from a human metastatic midgut carcinoid.
ANTICANCER RES. 2009; 29(6): 1951-1961.
[OPEN ACCESS]
Web of Science
PubMed
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** Rinner, B; Li, ZX; Haas, H; Siegl, V; Sturm, S; Stuppner, H; Pfragner, R
Antiproliferative and pro-apoptotic effects of Uncaria tomentosa in human medullary thyroid carcinoma cells.
Anticancer Res. 2009; 29(11): 4519-4528.
[OPEN ACCESS]
Web of Science
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** Siddique, ZL; Drozdov, I; Floch, J; Gustafsson, BI; Stunes, K; Pfragner, R; Kidd, M; Modlin, IM
KRJ-I and BON cell lines: defining an appropriate enterochromaffin cell neuroendocrine tumor model.
NEUROENDOCRINOLOGY. 2009; 89(4): 458-470.
Doi: 10.1159/000209330
Web of Science
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Abstract (Journal)
** Haas, HS; Pfragner, R; Siegl, V; Rinner, B; Wolf, P; Sadjak, A
Effects of peripheral glutamate receptors on tumor cell growth: liaisons of neurotransmitters and body functions.
AMINO ACIDS. 2009; 37: 99-100.-11th International Congress on Amino Acids, Peptides and Proteins; Aug 3-7; Vienna.
[Poster]
Web of Science
** Kalhan, A; Kidd, M; Modlin, I; Pfragner, R; Rees, DA; Ham, J
Adenosine A2 Receptor Signalling Mediates Chromogranin A Secretion from Neuroendocrine Tumors
NEUROENDOCRINOLOGY. 2009; 90(1):58--6th Annual ENETS Conference; March 5-7, 2009; Granada, Spain.
[Keynote lecture]
Web of Science
** Modlin, I; Kidd, M; Gustafsson, B; Pfragner, R
The EC Cell is Gut Chemo- and Mechanosensor Regulating Serotonin Release and Gastrointestinal Function
CHEM SENSES. 2009; 34(3):E9-E9.-18th Congress of the European-Chemoreception-Research-Organization; SEP 03-07, 2008; Bernardin, SLOVENIA.
[Oral Communication]
Web of Science
** Pfragner, R; Hoeger, H; Behmel, A; Beham, A; Stelzer, I; Obenauf, AC; Haas, HS; Ingolic, E; Siegl, V; Aguiriano-Moser, V; Svejda, B; Haas, O; Niederle, B
In vitro- and in vivo-models of human neuroendocrine tumors: three novel transplantable cell lines from metastatic midgut carcinoid.
AMINO ACIDS. 2009; 37: 103-103.-11th International Congress on Amino Acids, Peptides and Proteins; AUG 3-7; Vienna.
[Oral Communication]
Web of Science
2008
Full paper/article (Journal)
** Dubsky, P; Hayden, H; Sachet, M; Bachleitner-Hofmann, T; Hassler, M; Pfragner, R; Gnant, M; Stift, A; Friedl, J
Allogeneic tumor lysate can serve as both antigen source and protein supplementation for dendritic cell culture.
Cancer Immunol Immunother. 2008; 57(6): 859-870.
Doi: 10.1007/s00262-007-0422-0
Web of Science
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** Kidd, M; Drozdov, I; Joseph, R; Pfragner, R; Culler, M; Modlin, I
Differential cytotoxicity of novel somatostatin and dopamine chimeric compounds on bronchopulmonary and small intestinal neuroendocrine tumor cell lines.
Cancer. 2008; 113(4): 690-700.
Doi: 10.1002/cncr.23700
[OPEN ACCESS]
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** Kidd, M; Modlin, IM; Gustafsson, BI; Drozdov, I; Hauso, O; Pfragner, R
Luminal regulation of normal and neoplastic human EC cell serotonin release is mediated by bile salts, amines, tastants, and olfactants.
Am J Physiol Gastrointest Liver Physiol. 2008; 295(2): G260-G272.
Doi: 10.1152/ajpgi.00056.2008
[OPEN ACCESS]
Web of Science
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** Kidd, M; Schally, AV; Pfragner, R; Malfertheiner, MV; Modlin, IM
Inhibition of proliferation of small intestinal and bronchopulmonary neuroendocrine cell lines by using peptide analogs targeting receptors.
Cancer. 2008; 112(6): 1404-1414.
Doi: 10.1002/cncr.23303
[OPEN ACCESS]
Web of Science
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** Li, ZX; Sturm, S; Svejda, B; Hoger, H; Schraml, E; Ingolic, E; Siegl, V; Stuppner, H; Pfragner, R
Anticancer Activity of Novel Extracts from Cautleya gracilis (Smith) Dandy: Apoptosis in Human Medullary Thyroid Carcinoma Cells
ANTICANCER RES. 2008; 28(5A): 2705-2713.
Web of Science
** Stadler, G; Wieser, M; Streubel, B; Stift, A; Friedl, J; Gnant, M; Niederle, B; Beham, A; Katinger, H; Pfragner, R; Grillari, J; Voglauer, R
Low telomerase activity: possible role in the progression of human medullary thyroid carcinoma.
Eur J Cancer. 2008; 44(6): 866-875.
Doi: 10.1016/j.ejca.2007.12.014
[OPEN ACCESS]
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Short report/Letter
** Regauer, S; Emberger, W; Reich, O; Pfragner, R
Cytogenetic analyses of two new cases of endometrial stromal sarcoma--non-random reciprocal translocation t(10;17)(q22;p13) correlates with fibrous ESS.
Histopathology. 2008; 52(6):780-783
Doi: 10.1111/j.1365-2559.2008.03022.x
(- Case Report)
Web of Science
PubMed
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Abstract (Journal)
** Leitner, J; Stift, A; Friedl, J; Pfragner, R; Steinberger, P; Pfistershammer, K
Identification of tumor antigens using antibodies induced by dendritic cell (DC) based vaccines
WIEN KLIN WOCHENSCHR. 2008; 120: 9-10.
[Oral Communication]
Web of Science
** Pfragner, R; Behmel, A; Hoeger, H; Ingolic, E; Beham, A; Siegl, V; Haas, O; Niederle, B
ESTABLISHMENT AND CHARACTERIZATION OF THREE NOVEL CELL LINES DERIVED FROM HUMAN METASTATIC NEUROENDOCRINE TUMOR (NET)
ANTICANCER RES. 2008; 28(5C):532--8th International Conference of Anticancer Research; Oct 17-22, 2008; Kos, GREECE.
[Keynote lecture]
Web of Science
2007
Full paper/article (Journal)
** Haas, HS; Pfragner, R; Siegl, V; Ingolic, E; Heintz, E; Schraml, E; Schauenstein, K
The non-competitive metabotropic glutamate receptor-1 antagonist CPCCOEt inhibits the in vitro growth of human melanoma.
Oncol Rep. 2007; 17(6): 1399-1404.
Doi: 10.3892/or.17.6.1399
Web of Science
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** Kidd, M; Eick, GN; Modlin, IM; Pfragner, R; Champaneria, MC; Murren, J
Further delineation of the continuous human neoplastic enterochromaffin cell line, KRJ-I, and the inhibitory effects of lanreotide and rapamycin.
J MOLECULAR ENDOCRINOL. 2007; 38(1-2): 181-192.
Doi: 10.1677/jme.1.02037
[OPEN ACCESS]
Web of Science
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** Kidd, M; Modlin, IM; Pfragner, R; Eick, GN; Champaneria, MC; Chan, AK; Camp, RL; Mane, SM
Small bowel carcinoid (enterochromaffin cell) neoplasia exhibits transforming growth factor-beta1-mediated regulatory abnormalities including up-regulation of C-Myc and MTA1.
CANCER. 2007; 109(12): 2420-2431.
Doi: 10.1002/cncr.22725
[OPEN ACCESS]
Web of Science
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** Kidd, M; Nadler, B; Mane, S; Eick, G; Malfertheiner, M; Champaneria, M; Pfragner, R; Modlin, I
GeneChip, geNorm, and gastrointestinal tumors: novel reference genes for real-time PCR.
PHYSIOL GENOMICS. 2007; 30(3): 363-370.
Doi: 10.1152/physiolgenomics.00251.2006
[OPEN ACCESS]
Web of Science
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** Stadler, G; Wieser, M; Steindl, F; Grillari, J; Katinger, H; Pfragner, R; Voglauer, R
Development of standardized cell culture conditions for tumor cells with potential clinical application.
Cytotherapy. 2007; 9(5): 488-498.
Doi: 10.1080/14653240701385836
Web of Science
PubMed
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** Wolf, C; Lederer, K; Pfragner, R; Schauenstein, K; Ingolic, E; Siegl, V
Biocompatibility of ultra-high molecular weight polyethylene (UHMW-PE) stabilized with alpha-tocopherol used for joint endoprostheses assessed in vitro.
J Mater Sci Mater Med. 2007; 18(6): 1247-1252.
Doi: 10.1007/s10856-006-0098-6
Web of Science
PubMed
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Abstract (Journal)
** Kidd, M; Modlin, IM; Pfragner, R; Eick, GN; Champaneria, MC; Chan, AK; Camp, RL; Mane, SM
Small bowel carcinoid (ECCell) neoplasia exhibits TGF B1-mediated regulatory abnormalities including up-regulation of C-myc and Mta1
GASTROENTEROLOGY. 2007; 132(4): A310-A310.
Web of Science
2006
Full paper/article (Journal)
** Bachleitner-Hofmann, T; Strohschneider, M; Krieger, P; Sachet, M; Dubsky, P; Hayden, H; Schoppmann, SF; Pfragner, R; Gnant, M; Friedl, J; Stift, A
Heat shock treatment of tumor lysate-pulsed dendritic cells enhances their capacity to elicit antitumor T cell responses against medullary thyroid carcinoma.
J Clin Endocrinol Metab. 2006; 91(11): 4571-4577.
Doi: 10.1210/jc.2006-0971
[OPEN ACCESS]
Web of Science
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** Modlin, IM; Kidd, M; Pfragner, R; Eick, GN; Champaneria, MC
The functional characterization of normal and neoplastic human enterochromaffin cells.
J Clin Endocrinol Metab. 2006; 91(6):2340-2348
Doi: 10.1210/jc.2006-0110
[OPEN ACCESS]
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Correction
** Pfragner, R; Skofitsch, G; Hoger, H; Jech, M; Rinner, B; Siegl, V; Niederle, B; Gnant, M; Friedl, J; Stift, A
Medullary thyroid carcinoma: Autologous tumor cell lines for dendritic cell vaccination (vol 25, pg 4225, 2005)
ANTICANCER RES. 2006; 26(1A): 445-445.
Web of Science
Abstract (Journal)
** Eick, GN; Pfragner, R; Kidd, M; Champaneria, MC; Murren, JR; Modlin, IM
Characterization of a human neoplastic enterochromaffin (EC) cell line, KRJ-1 and the anti-proliferative effects of lanreotide and rapamycin
GASTROENTEROLOGY. 2006; 130(4): A534-A534.
Web of Science
** Modlin, IM; Kidd, M; Eick, GN; Champaneria, MC; Pfragner, R
The transcriptome and function of normal and neoplastic human EC cells
GASTROENTEROLOGY. 2006; 130(4): A704-A704.
Web of Science
2005
Full paper/article (Journal)
** Haas, HS; Pfragner, R; Siegl, V; Ingolic, E; Heintz, E; Schauenstein, K
Glutamate receptor-mediated effects on growth and morphology of human histiocytic lymphoma cells.
INT J ONCOL. 2005; 27(3): 867-874.
Web of Science
PubMed
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** Pfragner, R; Skofitsch, G; Höger, H; Jech, M; Rinner, B; Siegl, V; Niederle, B; Gnant, M; Friedl, J; Stift, A
Medullary thyroid carcinoma: autologous tumor cell lines for dendritic cell vaccination.
ANTICANCER RES. 2005; 25(6B): 4225-4230.
[OPEN ACCESS]
Web of Science
PubMed
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** Rockenstein, E; Schwach, G; Ingolic, E; Adame, A; Crews, L; Mante, M; Pfragner, R; Schreiner, E; Windisch, M; Masliah, E
Lysosomal pathology associated with alpha-synuclein accumulation in transgenic models using an eGFP fusion protein.
J NEUROSCI RES. 2005; 80(2): 247-259.
Doi: 10.1002/jnr.20446
Web of Science
PubMed
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** Voglauer, R; Grillari, J; Fortschegger, K; Wieser, M; Sterovsky, T; Gunsberg, P; Katinger, H; Pfragner, R
Establishment of human fibroma cell lines from a MEN1 patient by introduction of either hTERT or SV40 early region.
INT J ONCOL. 2005; 26(4): 961-970.
Doi: 10.3892/ijo.26.4.961
Web of Science
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Abstract (Journal)
** Emberger, W; Regauer, S; Sodial, S; Reich, O; Zierler, H; Wagner, K; Pfragner, R
Endometrial stromal sarcoma: cytogenetic and molecular cytogenetic analyses
EUR J CELL BIOL 2005 84: 17-17.
Web of Science
** Jech, M; Hutter-Paier, B; Ingolic, E; Hoger, H; Grygar, E; Porta, S; Poncza, B; Windisch, M; Pfragner, R
Characterization of two pheochromocytoma cell lines - In vitro models as new test systems for neuroendocrine research
EUR J CELL BIOL 2005 84: 22-22.
Web of Science
** Rinner, B; Greger, H; Brem, B; Purstner, P; Porta, S; Siegl, V; Pfragner, R
Alternative therapy with domestic plants against medullary thryroid carcinoma
EUR J CELL BIOL. 2005; 84: 111-111.-Annual Meeting of the Deutsche-Gesellschaft-fur-Zellbiologie; MAR 16-19, 2005; Heidelberg, GERMANY.
[Poster]
Web of Science
Full paper/article (Proceedings)
** Stadler, G; Voglauer, R; Wieser, M; Katinger, H; Pfragner, R
Establishment and characterization of human medullary thyroid carcinoma cell lines for immunotherapy
In: Godia, F, Fussenegger, M. editors(s). Animal Cell Technology Meets Genomics; 245-248. (ISBN: 1-4020-2791-5) ( Presented at: 18th Meeting of the European-Society-of-Animal-Cell-Technology (ESACT), Granada, SPAIN, MAY 11-14, 2003)
Web of Science
2004
Full paper/article (Journal)
** Kaczirek, K; Schindl, M; Weinhäusel, A; Scheuba, C; Passler, C; Prager, G; Raderer, M; Hamilton, G; Mittlböck, M; Siegl, V; Pfragner, R; Niederle, B
Cytotoxic activity of camptothecin and paclitaxel in newly established continuous human medullary thyroid carcinoma cell lines.
J CLIN ENDOCRINOL METAB. 2004; 89(5): 2397-2401.
Doi: 10.1210%2Fjc.2003-031314
[OPEN ACCESS]
Web of Science
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** Rinner, B; Siegl, V; Pürstner, P; Efferth, T; Brem, B; Greger, H; Pfragner, R
Activity of novel plant extracts against medullary thyroid carcinoma cells.
ANTICANCER RES. 2004; 24(2A): 495-500.
Doi: 10.1240/sav_gbm_2004_h_000597
[OPEN ACCESS]
Web of Science
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** Stift, A; Sachet, M; Yagubian, R; Bittermann, C; Dubsky, P; Brostjan, C; Pfragner, R; Niederle, B; Jakesz, R; Gnant, M; Friedl, J
Dendritic cell vaccination in medullary thyroid carcinoma.
CLIN CANCER RES. 2004; 10(9): 2944-2953.
Doi: 10.1158/1078-0432.CCR-03-0698
[OPEN ACCESS]
Web of Science
PubMed
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Abstract (Journal)
** Jech, M; Hutter-Paier, B; Ingolic, E; Hoeger, H; Grygar, E; Windisch, M; Pfragner, R
Pheochromocytoma cell lines of mouse and man
J INTERN MED. .. 2004; 255: 729-729.-9th Workshop on Multiple Endocrine Neoplasia; JUN 20-22, 2004; Bethesda, MD.
[Poster]
Web of Science
** Pfragner, R; Friedl, J; Stift, A; Niederle, B; Gnant, M
MEDULLARY THYROID CARCINOMAS: AUTOLOGOUS TUMOR CELL LINES FOR DENDRITIC CELL VACCINATION
ANTICANCER RES. 2004; 24(5D):398--7th International Conference of Anticancer Research; OCT 25-30, 2004; Corfu, GREECE.
Web of Science
** Pfragner, R; Voglauer, R; Stadler, G; Stift, A; Friedl, J; Niederle, B; Gnant, M
Medullary thyroid carcinoma cell lines for dendritic cell-based immunotherapy
J INTERN MED. 2004; 255(6):P1007--Nineth International Workshop on Multiple Endocrine Neoplasia (MEN 2004); JUN 20-22, 2004; Bethesda, MD.
[Poster]
Web of Science
** Regauer, S; Emberger, W; Reich, O; Liegl, B; Pfragner, R
Cytogenetic characterization of mucosa-associated malignant melanomas
J INVEST DERMATOL 2004 122: A156-A156.
Web of Science
** Rinner, B; Brem, B; Greger, H; Efferth, T; Puerstner, P; Siegl, V; Pfragner, R
Biological activity of plant extracts in medullary thyroid carcinoma
J INTERN MED. .. 2004; 255: 714-714.-9th Workshop on Multiple Endocrine Neoplasia; JUN 20-22, 2004; Bethesda, MD.
[Poster]
Web of Science
2003
Review
** Weinhäusel, A; Behmel, A; Ponder, BA; Haas, OA; Niederle, B; Gessl, A; Vierhapper, H; Pfragner, R
Long-term follow up of a sporadic unilateral pheochromocytoma revealing multiple endocrine neoplasia MEN2A-2 in an elderly woman.
Endocr Pathol. 2003; 14(4):375-382
Doi: 10.1385%2FEP%3A14%3A4%3A375
(- Case Report)
Web of Science
PubMed
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2002
Full paper/article (Journal)
** Bachleitner-Hofmann, T; Stift, A; Friedl, J; Pfragner, R; Radelbauer, K; Dubsky, P; Schüller, G; Benkö, T; Niederle, B; Brostjan, C; Jakesz, R; Gnant, M
Stimulation of autologous antitumor T-cell responses against medullary thyroid carcinoma using tumor lysate-pulsed dendritic cells.
J Clin Endocrinol Metab. 2002; 87(3):1098-1104
Doi: 10.1210%2Fjc.87.3.1098
[OPEN ACCESS]
Web of Science
PubMed
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** Heiser, M; Hutter-Paier, B; Jerkovic, L; Pfragner, R; Windisch, M; Becker-André, M; Dieplinger, H
Vitamin E binding protein afamin protects neuronal cells in vitro.
J Neural Transm Suppl. 2002; 14(62):337-345
Doi: 10.1007/978-3-7091-6139-5_32
Web of Science
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** Pfragner, R; Wirnsberger, GH; Ingolic, E; Niederle, B
Medullary thyroid carcinomas in cell culture--models for future therapies.
Wien Klin Wochenschr. 2002; 114(7):279-283
Web of Science
PubMed
** Pourani, J; Kaserer, K; Pfragner, R
Cytogenetic and molecular analyses of multiple endocrine neoplasias of the MEN1 syndrome.
Int J Oncol. 2002; 20(5):971-976
Doi: 10.3892/ijo.20.5.971
Web of Science
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Abstract (Journal)
** Derler, B; Schreiner, E; Tschemmernegg, M; Windisch, M; Koraimann, G; Pfragner, R
Establishment of a stably transfected neuronal cell line using an ecdysone inducible mammalian expression system carrying recombinant, mutant hAPP
NEUROBIOL AGING 2002 23: S19-S19.
Web of Science
Full paper/article (Proceedings)
** Heiser, M; Hutter-Paier, B; Jerkovic, L; Pfragner, R; Windisch, M; Becker-Andre, M; Dieplinger, H
Vitamin E binding protein Afamin protects neuronal cells in vitro
. 2002; 337-345.
Web of Science
2001
Full paper/article (Journal)
** Pfragner, R; Ullmann, R; Behmel, A; Popper, HH
Comparative genomic hybridization and cytogenetic analysis in a bronchial adenoma: three clones with different chromosomal aberrations.
Int J Oncol. 2001; 18(5):923-928
Doi: 10.3892/ijo.18.5.923
Web of Science
PubMed
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** Vrecko, K; Pfragner, R; Siegl, V; Schauenstein, K; Reibnegger, G
Effect of interferon-gamma and LPS on tetrahydrobiopterin in rat PC 12 and human KNA cells
PTERIDINES 2001 12: 167-171.
Doi: 10.1515/pteridines.2001.12.4.167
Web of Science
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Abstract (Journal)
** Weinhaeusel, AS; Waldner, P; Pfragner, R; Niederle, B; Haas, OA
Monoallelic expression of the paternal mutated allele in the pheochromocytoma of a patient with hereditary paraganglioma (PGL1) and a constitutional SDHD-gene mutation.
AMER J HUM GENET 2001 69: 256-256.
Web of Science
2000
Full paper/article (Journal)
** Egger, G; Pfragner, R; Siegl, V; Zatloukal, K; Glasner, A; Bader, A; Steindorfer, P
The affinity of MCF7 breast cancer cells to hyaluronan substrates of different molecular weight and concentrations in an in vitro model.
Int J Oncol. 2000; 17(5):1019-1023
Doi: 10.3892/ijo.17.5.1019
Web of Science
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Google Scholar
1999
Full paper/article (Journal)
** Sigl, E; Behmel, A; Henn, T; Wirnsberger, G; Weinhausl, A; Kaserer, K; Niederle, B; Pfragner, R
Cytogenetic and CGH studies of four neuroendocrine tumors and tumor-derived cell lines of a patient with multiple endocrine neoplasia type 1.
Int J Oncol. 1999; 15(1):41-51
Doi: 10.3892/ijo.15.1.41
(- Case Report)
Web of Science
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Short report/Letter
** Wirnsberger, GH; Pfragner, R
Comment on Efficacy of azithromycin in the treatment of cyclosporine-induced gingival hyperplasia in renal transplant recipients by Nash and Zaltzman.
Transplantation. 1999; 67(9):1289-1291
Doi: 10.1097%2F00007890-199905150-00018
Web of Science
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** Wirnsberger, GH; Pfragner, R; Holzer, H
Chronic bacterial inflammation of the gum: the main risk factor for posttransplant gingival hyperplasia?
Clin Nephrol. 1999; 51(1):63-64
Web of Science
PubMed
1998
Full paper/article (Journal)
** Pfragner, R; Behmel, A; Smith, DP; Ponder, BA; Wirnsberger, G; Rinner, I; Porta, S; Henn, T; Niederle, B
First continuous human pheochromocytoma cell line: KNA. Biological, cytogenetic and molecular characterization of KNA cells.
J Neurocytol. 1998; 27(3):175-186
Doi: 10.1023%2FA%3A1006959625068
Web of Science
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** Wirnsberger, GH; Pfragner, R; Mauric, A; Zach, R; Bogiatzis, A; Holzer, H
Effect of antibiotic treatment with azithromycin on cyclosporine A-induced gingival hyperplasia among renal transplant recipients.
TRANSPLANT PROC. 1998; 30(5): 2117-2119.
Doi: 10.1016%2FS0041-1345%2898%2900558-2
Web of Science
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1996
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** Pfragner, R; Wirnsberger, G; Niederle, B; Behmel, A; Rinner, I; Mandl, A; Wawrina, F; Luo, JS; Adamiker, D; Hoger, H; Ingolic, E; Schauenstein, K
Establishment of a Continuous Cell-Line from a Human Carcinoid of the Small-Intestine (KRJ-I) - Characterization and Effects of 5-Azacytidine on Proliferation
INT J ONCOL. 1996; 8: 513-520.
Doi: 10.3892/ijo.8.3.513
Web of Science
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1995
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** Eng, C; Mulligan, LM; Smith, DP; Healey, CS; Frilling, A; Raue, F; Neumann, HP; Pfragner, R; Behmel, A; Lorenzo, MJ
Mutation of the RET protooncogene in sporadic medullary thyroid carcinoma.
Genes Chromosomes Cancer. 1995; 12(3):209-212
Doi: 10.1002/gcc.2870120308
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** PFRAGNER, R; WIRNSBERGER, G; BEHMEL, A; NIEDERLE, B
MULTIPLE ENDOCRINE NEOPLASIA (MEN2A) APPROACHED BY CELL-CULTURE
J EXP CLIN CANCER RES. 1995; 14(1): 200-202.
Web of Science
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** SMEJKALJAGAR, L; PFRAGNER, R; BORANIC, M; SCHAUENSTEIN, K
EFFECT OF SEROTONIN AND SEROTONINERGIC AGENTS ON THE PROLIFERATION OF RAT LYMPHOID-CELLS AND CELL-LINES
J EXP CLIN CANCER RES. 1995; 14(1): 20-21.
Web of Science
1993
Full paper/article (Journal)
** Pfragner, R; Wirnsberger, G; Behmel, A; Wolf, G; Passath, A; Ingolic, E; Adamiker, D; Schauenstein, K
New Continuous Cell-Line from Human Medullary-Thyroid Carcinoma - SINJ - Phenotypic Analysis and Invivo Carcinogenesis
INT J ONCOL. 1993; 2: 831-836.
Doi: 10.3892/ijo.2.5.831
Web of Science
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** Popper, HH; Gamperl, R; Pongratz, MG; Kullnig, P; Jüttner-Smolle, FM; Pfragner, R
Chromosome typing in lymphangioleiomyomatosis of the lung with and without tuberous sclerosis.
Eur Respir J. 1993; 6(5):753-759
(- Case Report)
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1992
Full paper/article (Journal)
** Pfragner, R; Wirnsberger, G; Behmel, A; Niederle, B; Längle, F; Roka, R; Mandl, A; Pürstner, P; Auner, J; Tatzber, F
Biologic and cytogenetic characterization of three human medullary thyroid carcinomas in culture.
Henry Ford Hosp Med J. 1992; 40(3-4):299-302
PubMed
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** Pfragner, R; Wirnsberger, G; Mandl, A; Schauenstein, K
Production of CGRP in three continuous cell lines from human medullary thyroid carcinomas.
ANN N Y ACAD SCI. 1992; 657(1): 499-501.
Doi: 10.1111/j.1749-6632.1992.tb22812.x
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** Telenius, H; Pelmear, AH; Tunnacliffe, A; Carter, NP; Behmel, A; Ferguson-Smith, MA; Nordenskjöld, M; Pfragner, R; Ponder, BA
Cytogenetic analysis by chromosome painting using DOP-PCR amplified flow-sorted chromosomes.
GENE CHROMOSOME CANCER. 1992; 4(3): 257-263.
Doi: 10.1002/gcc.2870040311
Web of Science
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1990
Full paper/article (Journal)
** Pfragner, R; Höfler, H; Behmel, A; Ingolic, E; Walser, V
Establishment and characterization of continuous cell line MTC-SK derived from a human medullary thyroid carcinoma.
CANCER RES. 1990; 50(13): 4160-4166.
[OPEN ACCESS]
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1989
Abstract (Journal)
** BEHMEL, A; PFRAGNER, R
CHROMOSOMES IN CELL-LINES OF A HUMAN MEDULLARY-THYROID CARCINOMA
CANCER GENET CYTOGENET. 1989; 38(2): 191-191.
Doi: 10.1016/0165-4608(89)90628-6
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1988
Abstract (Journal)
** JAKSE, R; TILZ, G; PFRAGNER, R
DETECTION OF TRANSPLANTATION ANTIGENS IN AURICULAR CARTILAGE
ARCH OTO-RHINO-LARYNGOL. 1988; 245(6): 389-389.
Web of Science
Note
** Klimpfinger, M; Ruhri, C; Pütz, B; Pfragner, R; Wirnsberger, G; Höfler, H
Oncogene expression in a medullary thyroid carcinoma.
VIRCHOWS ARCH B CELL PATH. 1988; 54(4): 256-259.
Doi: 10.1007/BF02899220
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1987
Full paper/article (Journal)
** Kärcher, H; McNally, NJ; Wilson, G; Kärcher, KH; Pfragner, R
In-vivo marking of human tumors using BUDR for flow-cytometry determination of kinetic cell parameters
Strahlenther Onkol. 1987; 163(3): 195-200.
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Abstract (Journal)
** HOFLER, H; KLIMPFINGER, M; RUHRI, C; PFRAGNER, R; SPINDEL, ER; PUTZ, B; WIRNSBERGER, G
MEDULLARY-THYROID CARCINOMA - CHARACTERIZATION OF NEUROENDOCRINE GENE AND ONCOGENE EXPRESSION
LAB INVEST. 1987; 56(1): A31-A31.
Web of Science
** PFRAGNER, R; HOFLER, H; BEHMEL, A; FUGER, GF; INGOLIC, E; WALSER, V; WIRNSBERGER, G; RUHRI, C
ESTABLISHMENT AND CHARACTERIZATION OF A HUMAN MEDULLARY-THYROID CARCINOMA CELL-LINE - FUNCTIONAL AND MORPHOLOGICAL EFFECTS OF GROWTH-FACTORS
ANTICANCER RES. 1987; 7(5): 883-883.
Web of Science
1986
Abstract (Journal)
** TILLIAN, HM; KORSATKO, W; PFRAGNER, R
TESTING THE CYTOSTATIC EFFICIENCY IN THE EXAMPLE OF MICHAEL ADDUCTS OF ALPHA,BETA-UNSATURATED ALDEHYDES - EXTRACORPOREAL STUDY OF CELL DIVISIBILITY IN LONG-TERM THERAPY USING DELAYED ACTION IMPLANTATION TABLETS
Z VERSUCHSTIERK. 1986; 28(5): 238-238.
Web of Science
1985
Full paper/article (Journal)
** Kärcher, H; McNally, NJ; Wilson, G; Kärcher, KH; Pfragner, R
Flow cytometric measurements of in vivo incorporated bromodeoxy- uridine into the DNA of experimental and human tumors
WIEN KLIN WOCHENSCHR. 1985; 97(22): 850-855.
Web of Science
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** Kärcher, H; McNally, NJ; Wilson, G; Pfragner, R
Flow cytometry studies of incorporated bromodeoxyuridine (BUdR) in carcinoma of the oral cavity. A new method
Dtsch Z Mund Kiefer Gesichtschir. 1985; 9(5): 327-330.
PubMed
** Wilson, GD; McNally, NJ; Dunphy, E; Kärcher, H; Pfragner, R
The labelling index of human and mouse tumours assessed by bromodeoxyuridine staining in vitro and in vivo and flow cytometry.
CYTOMETRY. 1985; 6(6): 641-647.
Doi: 10.1002/cyto.990060621
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1984
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** KORSATKO, W; WABNEGG, B; TILLIAN, HM; EGGER, G; PFRAGNER, R; WALSER, V
POLY-D(-)-3-HYDROXYBUTYRIC ACID (POLY-HBA) - A BIODEGRADABLE FORMER FOR LONG-TERM MEDICATION DOSAGE .3. STUDIES ON COMPATIBILITY OF POLY-HBA - IMPLANTATION TABLETS IN TISSUE-CULTURE AND ANIMALS
PHARMAZ IND. 1984; 46(9): 952-954.
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** Pfragner, R; Sadjak, A; Walser, V
The effect of nerve growth factor (NGF) on the catecholamine contents of two human pheochromocytomas in tissue culture.
EXP PATHOL. 1984; 26(1): 21-31.
Doi: 10.1016/S0232-1513(84)80065-1
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Abstract (Journal)
** PFRAGNER, R; HÖFLER, H; DENK, H; INGOLIC, E; WALSER, V
LONG-TERM CULTIVATION OF A HUMAN BRONCHUS CARCINOID - ELECTRONMICROSCOPICAL AND IMMUNOHISTOCHEMICAL STUDIES
BIO CELL. 1984; 52(1):A50-A50.-European Tissue Culture Society 32nd Meeting; SEP 10 - 13, 1984; Milano, Italy.
Web of Science
1982
Full paper/article (Journal)
** Sadjak, A; Pfragner, R; Klingenberg, HG; Eskici, A; Tilz, GP
Antibody determination in homologous tooth transplants.
EXP PATHOL. 1982; 22(4): 253-255.
Doi: 10.1016/S0232-1513(82)80016-9
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1981
Full paper/article (Journal)
** Pfragner, R; Sadjak, A; Eskici, A; Walser, V
Pretransplantation treatment of human teeth in tissue culture combined with storage in liquid nitrogen. A scanning electron microscopic study.
EXP PATHOL. 1981; 20(2): 128-132.
Web of Science
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1980
Full paper/article (Journal)
** Pfragner, R; Porta, S; Walser, V; Korsatko, W
Effects of adrenaline-tablets on rat heart cells in tissue culture at normal and raised temperature.
EXP PATHOL-JENA. 1980; 18(6): 341-345.
Web of Science
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** Pfragner, R; Walser, V
Long-term tissue culture of human pheochromocytomas.
EXP PATHOL-JENA. 1980; 18(7-8): 423-429.
Doi: 10.1016/S0014-4908(80)80043-3
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Abstract (Journal)
** PFRAGNER, R; WALSER, V
CATECHOLAMINE - DETERMINATIONS IN HUMAN PHEOCHROMOCYTOMAS IN LONG-TERM TISSUE-CULTURE
EUR J CELL BIOL. 1980; 22(1): 606-606.
Web of Science
1971
Full paper/article (Journal)
** Kellner, G; Pfragner, R; Kronberger, L
Experimental cytologic study of the effect of potassium-magnesium-aspartate on human fibroblasts and HeLa cells in tissue culture
Z Krebsforsch. 1971; 75(4): 269-276.
Doi: 10.1007/BF00641958
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