Dutta, S; Rezania, S; Lyssy, F; Lind, K; Vosberg, S; Thallinger, G; Zebisch, A; Wölfler, A; Pabst, G; Foßelteder, J; Reinisch, A; Sill, H;
Deciphering the molecular mechanism of mesenchymal stromal cell mediated drug resistance in acute myeloid leukemia.
29th European Hematology Association Congress; JUN 13-16, 2024; Madrid, SPAIN. 2024.
[Poster]
Balihodzic, A; Fernandez Hernandez, FJ; Jäger, V; Vosberg, S; Schnur, T; Kainz, G; Gallé, B; Schweintzger, N; Kühberger, S; Heitzer, E; Reinisch, A; Jost, PJ; Pichler, M; Dengler, MA
Application of genome-wide CRISPR/Cas9 screen to identify synthetic lethality with MCL-1 inhibition in lung cancer.
Proceedings of the Annual Meeting of the Austrian Society of Haematology and Medical Oncology. 2023; 16: 1-28.-OeGHO- & AHOP-Frühjahrstagung 2023; März 30-April 1, 2023; Innsbruck, AUSTRIA.
[Oral Communication]
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Balihodzic, A; Fernandez-Hernandez, FJ; Jäger, V; Vosberg, S; Tonietto, M; Schnur, T; Kainz, G; Gallé, B; Schweintzger, N; Kühberger, S; Heitzer, E; Reinisch, A; Jost, PJ; Pichler, M; Dengler, MA
Application of genome-wide CRISPR/Cas9 screen to identify synthetic lethality with MCL-1 inhibition in lung cancer
Doctoral Day of Medical University of Graz; FEB 9, 2023; Graz, AUSTRIA. 2023.
[Poster]
Dutta, S; Kerbs, P; Rothenberg-Thurley, M; Ksienzyk, B; Krebs, S; Blum, H; Spiekermann, K; Metzeler, KH; Herold, T; Dandachi, N; Vosberg, S; Greif, PA;
FREQUENT TRUNCATING MUTATIONS IN TET2 GENE AND A DISTINCT DNA METHYLATION SIGNATURE CHARACTERIZES ACUTE MYELOID LEUKEMIA WITH ISOLATED TRISOMY 4
ANN HEMATOL. 2023; 102(SUPPL 1):S26-S27.-ACUTE LEUKEMIAS XVIII .ISALXVIII
BIOLOGY AND TREATMENT STRATEGIES; March 19-20, 2023; Munich Germany.
[Poster]
Web of Science
Hilbers, F; Venet, D; Agostinetto, E; Benelli, M; Guerrero, A; Martins-Branco, D; Raimbault, A; Fimereli, D; Ferrando, L; Sommariva, S; Biagioni, C; Paoli, M; Llinas-Bertran, A; Dadiani, M; Zoppoli, G; Balic, M; Albanell, J; Vosberg, S; Irrthum, A; Salgado, R
Characterization of the immune microenvironment in matched primary and metastatic breast cancer lesions from the AURORA study: BIG 14-01
J CLIN ONCOL. 2023; 41(16):
[Poster]
Web of Science
Jäger, V; Flasch, B; Vosberg, S; Fernandez-Hernandez, F; Balihodzic, A; Kienreich, S; Stanzer, S; Herold, M; Kargl, J; Dengler, M; Jost, P
Uncovering innovative molecular targets for lung cancer therapy on the highly recurrent chromosomal gain of 1q21
OeGHO- & AHOP-Frühjahrstagung 2023; Proceedings of the Annual Meeting of the Austrian Society of Haematology and Medical Oncology; MAR 30-APR 1; Innsbruck, Austria. 2023.
[Poster]
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Jäger, V; Flasch, B; Vosberg, S; Fernandez-Hernandez, F; Balihodzic, A; Kienreich, S; Stanzer, S; Herold, M; Kargl, J; Dengler, M; Jost, P
Uncovering innovative molecular targets for lung cancer therapy on the highly recurrent chromosomal gain of 1q21
Doctoral Day of Medical University of Graz; FEB 9; Graz, AUSTRIA. 2023.
[Poster]
Jäger, V; Flasch, B; Vosberg, S; Fernandez-Hernandez, F; Tonietto M; Balihodzic, A; Kienreich, S; Stanzer, S; Herold, M; Kindler, O; Maitz, K; Kargl, J; Dengler, M; Jost, P
Oncogene or tumor-suppressor? - Functional characterization of the plasma membrane rupture mediator Ninjurin 1 in lung cancer
13th Scientific Retreat of the DK-MCD; SEP 25-27; Seggau, AUSTRIA. 2023.
[Oral Communication]
Shahbaz, W; Jurinovic, V; Batcha, AMN; Rausch, C; Rothenberg-Thurley, M; Dufour, AM; Ksienzyk, B; Schneider, S; Neusser, M; Sauerland, MC; Görlich, D; Berdel, WE; Woermann, BJ; Krug, U; Braess, J; Hiddemann, W; Mansmann, U; Vosberg, S; Greif, PA; Spiekermann, K; Metzeler, KH; Herold, T
D DX41-Low Expression Mimics Germline DDX41-Phenotype in Acute Myeloid Leukemia
BLOOD. 2023; 142:
Doi: 10.1182/blood-2023-187419
Web of Science
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Vosberg, S; Ohnmacht, A; Moser, C; Arneth, A; Jurinovic, V; Metzeler, KH; Amler, S; Sauerland, MC; Görlich, D; Berdel, WE; Braess, J; Hiddemann, W; Spiekermann, K; Oakes, CC; Menden, MP; Herold, T; Greif, PA
REFINING THE PROGNOSTIC CLASSIFICATION OF ACUTE MYELOID LEUKEMIA BASED ON DNA METHYLATION PROFILING
ANN HEMATOL. 2023; 102(SUPPL 1): S42-S43.
[Poster]
Web of Science
Allmendinger, F; Agrawal, D; Dietzen, M; Vosberg, S; Munkhbaatar, E; McGranahan, N; Jost, P
Inflammatory cell death acts as tumor suppressor in lung adenocarcinoma
INTERNIST. 2022; 63(SUPPL 3):338-339.
[Oral Communication]
Web of Science
Dutta, S; Kerbs, P; Rothenberg-Thurley, M; Ksienzyk, B; Krebs, S; Blum, H; Spiekermann, K; Metzeler, KH; Herold, T; Vosberg, S; Greif, PA
Acute Myeloid Leukemia with Isolated Trisomy 4 Is Characterized By Frequent Mutations of TET2 and a Distinct DNA Methylation Signature
BLOOD. 2022; 140: 8912-8913.-64th American Society of Hematology Annual Meeting and Exposition; December 10-13, 2022; New Orleans USA.
Doi: 10.1182/blood-2022-168939
[Poster]
Web of Science
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Ruhnke, L; Frimmel, J; Rollig, C; Mohr, B; Altmann, H; Poitz, D; Zukunft, S; Schranz, K; Vosberg, S; Spiekermann, K; von Bergwelt, M; Jost, E; Dressler, S; Schafer-Eckart, K; Chavakis, T; Aust, D; Johrens, K; Baretton, G; Bornhauser, M; Greif, PA; Stolzel, F; Herold, S; Wagenfuhr, L
Prevalence, Clinical and Molecular Features, and Prognostic Value of Tetraploidy/Near-Tetraploidy in Patients with Acute Myeloid Leukemia
BLOOD. 2022; 140: 3454-3455.
Doi: 10.1182/blood-2022-166271
Web of Science
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Vosberg, S
Longitudinal (epi-)genomics of human cancers: Identifying evolutionary patterns during therapy.
Festival of Genomics and Biodata; JAN 25-28, 2022; London, ENGLAND. 2022.
[Oral Communication]
Vosberg, S; Kerbs, P; Spiekermann, K; Greif, P
DNA methylation profling reveal mechanisms of relapse specifc gene expression in acute myeloid leukemia
memo - Magazine of European Medical Oncology volume 15, pages37–67 (2022). 2022; -Annual Meeting of the Austrian Society of Haematology and Medical Oncology; APR 8-10, 2022; Graz.
[Poster]
Vosberg, S; Ohnmacht, A; Moser, C; Arneth, A; Jurinovic, V; Metzeler, KH; Sauerland, MC; Görlich, D; Berdel, WE; Braess, J; Amler, S; Krug, U; Hiddemann, W; Spiekermann, K; Oakes, CC; Menden, MP; Herold, T; Greif, PA
DNA Methylation Profiling Refines The Prognostic Classification Of Acute Myeloid Leukemia Patients Treated With Intensive Chemotherapy
Hemasphere. 2022 Jun; 6(Suppl ): 1-4130.. 2022; -27th Annual Meeting of the European Hematology Association; JUN 9-12, 2022; Wien.
[Poster]
Allmendinger, F; Agrawal, D; Dietzen, M; Vosberg, S; Munkhbaatar, E; Branca, C; McGranahan, N; Jost, PJ
RIPK3 downregulation in lung cancer alters the tumor immune micro-environment supporting tumor progression
ONCOL RES TREAT. 2021; 44: 51-52.
Web of Science
Allmendinger, F; Agrawal, D; Dietzen, M; Vosberg, S; Munkhbaatar, E; McGranahan, N; Jost, PJ
Necroptosis establishes an inflammatory tumor immune microenvironment acting as tumor suppressor in lung adenocarcinoma
ANN ONCOL. 2021; 32: S945-S945.
Doi: 10.1016/j.annonc.2021.08.1788
[Poster]
Web of Science
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Vosberg, S; Kerbs, P; Spiekermann, K; Greif, PA
Evolution of acute myeloid leukemia from diagnosis to relapse: integrating genomics, transcriptomics, and epigenomics.
12th Annual Meeting of the Austrian Association of Molecular Life Science and Biotechnology; 2021.
[Oral Communication]
Vosberg, S; Jurinovic, V; Kerbs, P; Metzeler, KH; Amler, S; Sauerland, MC; Görlich, G; Berdel, WE; Braess, J; Rothenberg-Thurley, M; Ksienzyk, B; Dufour, A; Schneider, S; Hiddemann, W; Spiekermann, K; Herold, T; Greif, PA
DNA methylation profiling enables prognostic classification of intensively treated Acute Myeloid Leukemia patients.
EHA Open Access Library. 2020; -25th Annual Meeting of the European Hematology Association; JUN 11 - OCT 15, 202; The Hague, The Netherlands.
[Poster]
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Vosberg, S; Kerbs, P; Spiekermann, K; Greif, PA
Evolution of acute myeloid leukemia from diagnosis to relapse: integrating genomics, epigenomics and transcriptomics
27th Congress of the European Association for Cancer Research; 2020.
[Poster]
Vosberg, S; Kerbs, P; Jurinovic, V; Metzeler, KH; Amler, S; Sauerland, C; Görlich, G; Berdel, WE; Braess, J; Hiddemann, W; Spiekermann, K; Herold, T; Greif, PA
DNA methylation profiling of AML reveals epigenetic subgroups with distinct clinical outcome.
Blood. 2019; 134: -61st Annual Meeting of the American Society of Hematology; DEC 11-14, 2019; Orlando, USA.
[Poster]
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Dutta S, Kerbs P, Vosberg S, Rothenberg-Thurley M, Ksienzyk B, Krebs,S Blum H, Hiddemann W Spiekermann K, Metzeler KH, Herold T, Greif PA
Acute Myeloid Leukemia with Isolated Trisomy 4 is Characterized by Frequent Mutations of TET2
SFB 1243 International Symposium: Cancer Evolution; March 1-3, 2018; Munich. 2018.
[Poster]
Vosberg, S; Hartmann, L; Metzeler, KH; Konstandin, NP; Schneider, S; Varadharajan, A; Hauser, A; Krebs, S; Blum, H; Bohlander, SK; Hiddemann, W; Tischer, J; Spiekermann, K; Greif, PA
Relapse of acute myeloid leukemia after allogeneic stem cell transplantation is associated with gain of WT1 alterations and high mutation load.
10th International Symposium Stem Cells and Cancer; Heidelberg, Germany. 2018.
[Oral Communication]
Vosberg, S; Hartmann, L; Metzeler, KH; Schumacher, D; Pastore, F; Bräundl, K; Zellmeier, E; Ksienzyk, B; Konstandin, NP; Schneider, S; Graf, A; Krebs, S; Blum, H; Neumann, M; Baldus, CD; Bohlander, SK; Wolf, S; Hiddemann, W; Spiekermann, K; Greif, PA
Evolutionary Patterns of Cytogenetically Normal Acute Myeloid Leukemia Correlate with Time to Relapse.
Annals of Hematology. 2017; 96: -Acute Leukemias Meeting XVI; FEB 19–22, 2017; Munich, Germany.
[Poster]
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Vosberg, S; Hartmann, L; Metzeler, KH; Schumacher, D; Pastore, F; Bräundl, K; Zellmeier, E; Ksienzyk, B; Konstandin, NP; Schneider, S; Graf, A; Krebs, S; Blum, H; Neumann, M; Baldus, CD; Bohlander, SK; Wolf, S; Hiddemann, W; Spiekermann, K; Greif, PA
Gain of Mutations Is Associated with Longer Time to Relapse in Acute Myeloid Leukemia
4th International Conference on Acute Myeloid Leukemia; Estoril, Portugal. 2017.
[Poster]
Vosberg, S; Hartmann, L; Metzeler, KH; Schumacher, D; Pastore, F; Bräundl, K; Zellmeier, E; Ksienzyk, B; Konstandin, NP; Schneider, S; Graf, A; Krebs, S; Blum, H; Neumann, M; Baldus, CD; Bohlander, SK; Wolf, S; Hiddemann, W; Spiekermann, K; Greif, PA
Evolutionary Patterns of Cytogenetically Normal Acute Myeloid Leukemia Correlate with Time to Relapse.
Blood (2016) . 2016; -58th Annual Meeting of the American Society of Hematology; DEC 3-6, 2016; San Diego, USA.
[Oral Communication]
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Vosberg, S; Greif, PA; Hartmann, L; Metzeler, KH; Schumacher, D; Pastore, F; Bräundl, K; Zellmeier, E; Ksienzyk, B; Konstandin, NP; Schneider, S; Graf, A; Krebs, S; Blum, H; Neumann, M; Baldus, CD; Bohlander, SK; Assenov, Y; Plass, C; Wolf, S; Wiemann, S; Hiddemann, W; Spiekermann, K
Genetic and Epigenetic Evolution during the Progression of Cytogenetically Normal Acute Myeloid Leukemia (CN-AML).
EHA Open Access Library. 2015; -20th Annual Meeting of the European Hematology Association; JUN 11-14, 2015; Vienna, Austria.
[Poster]
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Vosberg, S; Hartmann, L; Schneider, S; Metzeler, KH; Ksienzyk, B; Bräundl, K; Neumann, M; Baldus, CD; Graf, A; Krebs, S; Blum, H; Spiekermann, K; Bohlander, SK; Mansmann, U; Greif, PA
Detection of Chromosomal Aberrations in Acute Myeloid Leukemia By Copy Number Alteration Analysis of Exome Sequencing Data.
Blood. 2015; 126(23):-57th Annual Meeting of the American Society of Hematology; DEC 5-8, 2015; Orlando, USA.
[Poster]
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Vosberg, S; Herold, T; Metzeler, KH; Schneider, S; Ksienzyk, B; Graf, A; Krebs, S; Blum, H; Spiekermann, K; Bohlander, SK; Hiddemann, W; Mansmann, U; Greif, PA
Detection of Chromosome 9q Deletion in Acute Myeloid Leukemia (AML) Patients Using Targeted Sequencing Data.
Annals of Hematology. 2015; 94: -Acute Leukemias Meeting XV; FEB 22 – 25, 2015; Munich, Germany.
[Poster]
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Dutta S, Krause A, Vosberg S, Herold T, Ksienzyk B, Quintanilla-Fend L, Tizazu B, Graf A, Krebs S, Blum H, Greif PA, Schneider M, Dahlhof M, Spiekermann K, Zimber-Strobl U, Wolf E, Bohlander SK
Analysis of the Tissue-Specific Expression Requirements and Identification of Cooperating Mutations for Leukemogenesis in an Inducible CALM/AF10 Knock-in Mouse Model
Blood Journal Volume 124, Issue 21 . 2014; -56th ASH Annual meeting (American Society of Hematology) ; Dec 6-9, 2014; San Francisco, USA.
[Oral Communication]
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Vosberg, S
Exome Sequencing of Mice and Men: Discovery of Leukemia Drivers.
Genes, Genetics & Genomics Symposium; Prague, Czech Republic. 2014.
[Oral Communication]
Vosberg, S; Herold, T; Metzeler, KH; Schneider, S; Ksienzyk, B; Graf, A; Krebs, S; Blum, H; Spiekermann, K; Bohlander, SK; Mansmann, U; Greif, PA
Copy Number Alteration (CNA) Analysis in Targeted Sequencing Data from Acute Myeloid Leukemia (AML) Patients with Chromosome 9q Deletion.
Blood. 2014; 124(21):-56th Annual Meeting of the American Society of Hematology; DEC 6-9, 2014; San Francisco, USA.
[Poster]
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Vosberg, S; Herold, T; Sandhöfer, N; Göhring,, G; Graf, A; Krebs, S; Blum, H; Schlegelberger, B; Spiekermann, K; Bohlander, SK; Greif, PA
Detecting Chromosomal Alterations in Acute Myeloid Leukemia (AML) Patients by Exome Sequencing: a Copy Number Approach.
Galaxy Community Conference; Oslo, Norway. 2013.
[Poster]
Vosberg, S; Herold, T; Sandhöfer, N; Graf, A; Krebs, S; Blum, H; Spiekermann, K; Bohlander, SK; Greif, PA
Detection of Copy Number Alterations (CNAs) in Exome Sequence Data Sets of Acute Myeloid Leukemia (AML).
Annals of Hematology. 2013; 92: -Acute Leukemias Meeting XIV; FEB 24-27, 2013; Munich, Germany.
[Poster]
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