Medizinische Universität Graz - Research portal
Hasenleithner Samantha |
Presentations at scientific and public conferences
Dobrić, N; Dandachi, N; Klocker, EV; Suppan, C; Graf, R; Hasenleithner, S; Jost, PJ; Heitzer, E; Balic, M
Comparison of ctDNA profiles from HR+/HER2-low and HR+/HER2-0 advanced breast cancer patients.
Proceedings of the 13th International Symposium on Circulating Nucleic Acids in Plasma and Serum (CNAPS). 2024; -13th International Symposium on Circulating Nucleic Acids in Plasma and Serum (CNAPS); MAR 4-6, 2024; Graz, AUSTRIA.
[Poster]
Dobrić, N; Dandachi, N; Klocker, EV; Suppan, C; Graf, R; Hasenleithner, S; Jost, PJ; Heitzer, E; Balic, M
ctDNA profiling of HR+/HER2-low and HR+/HER2-0 metastatic breast cancer patients.
Molecular Oncology Supplement: EACR 2024: Innovative Cancer Science. 2024; 18(S1):i-ii.-EACR 2024 Congress: Innovative Cancer Science; JUN 10-13, 2024; Rotterdam, THE NETHERLANDS.
[Poster]
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Jonas, K; Riedl, JM; Steinlechner, SM; Moik, F; Jahn, S; Hasenleitner, S; Doleschal, B; Weiss, L; Seeber, A; Rumpold, H; Winder, T; Greil, R; Höfler, G; Gerger, A; Jost, P; Heitzer, E;
Low-level variants present a challenge in the clinical interpretation of liquid-biopsy-based comprehensive genomic profiling for patients with solid tumors
EACR Liquid Biopsies Conference; NOV 12-14, 2024; Lyon, FRANCE. 2024.
[Oral Communication]
Lazzeri, I; Spiegl, BG; Hasenleithner, S; Speicher, M; Kircher, M;
LBFextract: unveiling transcription factor dynamics from liquid biopsy data
EACR - Liquid Biopsies; NOV 12-14, 2024; Lyon, FRANCE. 2024.
[Poster]
Lazzeri, I; Spiegl, BG; Hasenleithner, S; Speicher, M; Kircher, M;
LBFextract: unveiling transcription factor dynamics from liquid biopsy data
Scientific Retreat of the Diagnostic and Research Center for Molecular Biomedicine; FEB 5, 2024; Graz, Austria. 2024.
[Poster]
Lazzeri, I; Spiegl, BG; Hasenleithner, S; Speicher, M; Kircher, M;
LBFextract: unveiling condition-specific transcription factors from liquid biopsy data
Austrian Bioinformatics Workshop; JUL 3,2024; Graz, AUSTRIA. 2024.
[Poster]
Moik, F; Riedl, JM; Edlinger, L; Esterl, T; Hasenleithner, S; Kostmann, S; Cebular, L; Jahn, S; Kashofer, K; Zacharias, M; Hoefler, G; Heitzer, E; Gerger, A; Jost, PJ
Practice patterns and treatment outcomes of molecular tumour board (MTB)-based personalized cancer therapies: A single-center experience
ANN ONCOL. 2024; 35: S262-S263.
Doi: 10.1016/j.annonc.2024.08.130
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Spiegl, B; Lazzeri, I; Hasenleithner, S; Kircher, M; Heitzer, E
Chromatin Compaction in Cancer: the Link Between Nucleosome Repeat Length and DNA Fragmentation
EACR Conference Liquid Biopsies; NOV 12-14, 2024; Lyon, FRANCE. 2024.
[Poster]
Dobric, N; Dandachi, N; Klocker, EV; Suppan, C; Graf, R; Hasenleithner, S; Jost, PJ; Heitzer, E; Balic, M
Comparison of ctDNA profiles from HR+/HER2-low and HR+/HER2-0 advanced breast cancer patients
ANN ONCOL. 2023; 34: S387-S387.-Annual Meeting of the European-Society-for-Medical-Oncology (ESMO); OCT 20-24, 2023; Madrid, SPAIN.
Doi: 10.1016/j.annonc.2023.09.667
[Poster]
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Dobric, N; Dandachi, N; Klocker, EV; Suppan, C; Graf, R; Hasenleithner, S; Jost, PJ; Heitzer, E; Balic, M.
Comparison of ctDNA fraction and mutational profiles of plasma samples of HR+/HER2-low and HR+/HER2-0 advanced breast cancer patients
6th ACTC - Advances in Circulating Tumor Cells Book of Abstracts. 2023; -6th ACTC - Advances in Circulating Tumor Cells; SEP 20-23, 2023; Skiathos, GREECE.
[Poster]
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Riedl, JM; Steinlechner, SM; Moik, F; Heitzer, E; Jahn, S; Hasenleithner, S; Doleschal, B; Weiss, L; Seeber, A; Rumpold, H; Winder, T; Greil, R; Jost, PJ; Hoefler, G; Speicher, M; Gerger, A
SOUND: A phase II trial evaluating the efficacy of molecular profiling of circulating ± tumor tissue DNA for salvagetherapy matching in patients with advanced and refractory carcinoma
ANN ONCOL. 2023; 34: S1186-S1186.-Annual Meeting of the European-Society-for-Medical-Oncology (ESMO); OCT 20-24, 2023; Barcelona, SPAIN.
Doi: 10.1016/j.annonc.2023.09.1349
[Poster]
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Gerger, A; Riedl, J; Hasenleithner, SO; Höfler, G; Jahn, S; Esterl, T; Jost, PJ; Speicher, MR; Heitzer, E.
Identifizierung von Tumorprädispositionen im Rahmen von klinischen ctDNA-Tests
ÖGH Jahrestagung; Sep 29, 2022; Graz, AUSTRIA. 2022.
[Oral Communication]
Moser, T; Hasenleithner, SO; Waldispuehl-Geigl, J; Zhou, Q; Weber, S; Graf, R; Geigl, JB; Heitzer, E; Speicher, MR
It’s in our blood: Improving cancer treatment monitoring via liquid biomarkers.
Festival of Genomics & Biodata; JAN 25-28, 2022; London, ENGLAND. 2022.
[Oral Communication]
Kühberger, S; Weber, S; Graf, R; Moser, T; Spiegl, B, Hasenleithner, SO; Speicher, MR; Schuuring, E; Groen, HJM; Heitzer, E.
Genomewide copy number calling from enriched sequencing data to identify clinically relevant somatic copy number alterations
5th Advances in Circulating Tumor Cells: “Liquid Biopsy in its best” (ACTC 2021) ; SEP 22-25, 2021; Kalamata, GREECE. 2021.
[Poster]
Perakis, SO; Weber, S; Zhou, Q; Graf, R; Hojas, S; Riedl, JM; Gerger, A; Dandachi, N; Balic, M; Hoefler, G, Schuuring, E; Groen, HJM; Geigl, JB; Heiter, E; Speicher, MR
Harnessing circulating tumor DNA to inform clinical decisions
Festival of Genomics & Biodata 2021; JAN 26-29, 2021; London, ENGLAND. 2021.
[Onlinepräsentation]
Weber, S; van der Leest, P; Donker, HC; Schlange, T; Timens, W; Tamminga, M; Hasenleithner, SO; Graf, R; Moser, T; Spiegl, B; Yaspo, ML, Terstappen, LWMM; Sidorenkov, G; Hiltermann, TJN; Speicher, MR; Schuuring, E; Groen, HJM;Heitzer, E.
Dynamic changes of circulating tumor DNA predict clinical outcome in advanced non-small cell lung cancer patients treated with immune checkpoint inhibitors
5th Advances in Circulating Tumor Cells: “Liquid Biopsy in its best” (ACTC 2021) ; SEP 22-25, 2021; Kalamata, GREECE. 2021.
[Poster]
Gerger, A; Riedl, JM; Perakis, S; Pregartner, G; Scheipner, L; Posch, F; Groller, K; Kashofer, K; Jahn, SW; Bauernhofer, T; Pichler, M; Stoger, H; Berghold, A; Hofler, G; Speicher, M; Heitzer, E
Profiling of circulating tumour DNA for treatment selection in patients with advanced and refractory carcinoma: A prospective, two-stage phase II individualized cancer treatment trial.
ANN ONCOL. 2020; 31: S1095-S1096.-ESMO Virtual Congress; SEP 19-OCT 18, 2020; ELECTR NETWORK.
Doi: 10.1016/j.annonc.2020.08.1331
[Onlinepräsentation]
[OPEN ACCESS]
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Moser, T; Waldispuehl-Geigl, J; Belic, J; Perakis, S; Weber, S; Zhou, Q; Sill, H; Lax, S; Kashofer, K; Hoefler, G; Schoellnast, H; Bauernhofer, T; Heitzer, E; Geigl, JB; Speicher, MR
Early circulating tumor DNA dynamics as a real-time predictor of FOLFOX efficacy in advanced colorectal cancer patients
CANCER RES. 2020; 80(16):
Doi: 10.1158/1538-7445.AM2020-4295
[Poster]
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Moser, T; Waldispuehl-Geigl, J; Belic, J; Weber, S; Zhou, Q; Hasenleithner, S; Graf, R; Terzic, JA; Posch, F; Sill, H; Lax, S; Kashofer, K; Hoefler, G; Schoellnast, H; Bauernhofer, T; Heitzer, E; Geigl, JB; Speicher, MR
Real-time measurements of circulating tumor DNA levels during FOLFOX treatment in patients with colorectal cancer.
4th Annual Meeting of the ÖPPM; Vienna, AUSTRIA. 2020.
[Poster]
Perakis, SO; Weber, S; Graf, R; Zhou, Q; Riedl, JM; Dandachi, N; Balic, M; Gerger, A; Schuuring, E; Groen, HJ; Geigl, JB; Speicher, MR; Heitzer, E
Identification of actionable targets in advanced cancer patients from circulating tumor DNA using clinical decision support platforms
CANCER RES. 2020; 80(16):-AACR Annual Meeting; JUN 22-24, 2020; ELECTR NETWORK.
Doi: 10.1158/1538-7445.AM2020-1315
[Poster]
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Perakis, SO; Weber, S; Zhou, Q; Graf, R; Hojas, S; Riedl, JM; Gerger, A; Dandachi, N; Balic, M; Hoefler, G; Schuuring, E; Groen, HJM; Geigl, JB; Heitzer, E; Speicher, MR
Liquid biopsy profiling of advanced cancer patients for clinical decision support platform analysis.
ÖGPath Frühjahrstagung 2020; SEP 11-12, 2020; Vienna, AUSTRIA. 2020.
[Oral Communication]
Riedl, J; Perakis, S; Pregartner, G; Scheipner, L; Posch, F; Groller, K; Kashofer, K; Jahn, SW; Bauernhofer, T; Pichler, M; Stoger, H; Berghold, A; Hofler, G; Speicher, M; Heitzer, E; Gerger, A
Individualized cancer treatment based on molecular profiling of circulating tumor DNA in patients with advanced and refractory carcinoma: a prospective phase II trial.
ONCOL RES TREAT. 2020; 43(SUPPL 4):249-249.-DGHO Jahrestagung; 09.10. -11.10.2020; Basel (virtueller Kongress).
[Oral Communication]
Web of Science
Lazzeri, I; Perakis, S; Moser, T; Zhou, Q; Ulz, P; Speicher, M; Heitzer, E
Building a cell type specific signature matrix for methylation based tissue deconvolution
DOCTORAL DAY 2019; NOV 20, 2019; Graz, Austria. 2019.
[Poster]
Moser, T; Perakis, S; Pichler, M; Seles, M; Wcislo, G; Speicher, MR; Heitzer, E
Molecular profiling of circulating tumor DNA in plasma of patients with renal cancer.
30th Annual Meeting of the German Society of Humangenetics ; MAR 6-8, 2019; Weimar, GERMANY. 2019.
[Poster]
Moser, T; Smith, CG; Seles, M; Wcislo, G; Eldridge, M; Perakis, S; Mouliere, F; Lazzeri, I; Heider, K; Warren, A; Rosenfeld, N; Stewart, GD; Heitzer, E
Comprehensive characterization of cell-free tumor DNA in plasma and urine of patients with renal tumors.
CANCER RES. 2019; 79(13):-AACR Annual Meeting on Bioinformatics, Convergence Science, and Systems Biology; MAR 29-APR 03, 2019; Atlanta, GA.
Doi: 10.1158/1538-7445.AM2019-1367
[Poster]
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Moser, T; Smith, CG; Seles, M; Wcislo, G; Eldridge, M; Perakis, S; Mouliere, F; Lazzeri, I; Heider, K; Warren, A; Rosenfeld, N; Stewart GD; Heitzer, E
Comprehensive characterisation of cell-free tumour DNA in plasma and urine of patients with renal tumours.
Current Developments in Non-invasive Biomarkers for Assessment of Cancer 2. 2019; -AACR; MAR 29-APR 3, 2019; Atlanta, Georgia, USA.
[Poster]
Perakis, S; Ulz, P; Riedl, JM; Scheipner, L; Kashofer, K; Höfler, G; Geigl, JB; Speicher, MR; Heitzer, E; Gerger, A
Molecular-biological tumor profiling for drug treatment selection in patients with advanced and refractory carcinoma: A prospective, two-stage phase II individualized cancer treatment study
The Next Generation of Clinical Trials in Molecularly Driven Therapy. 2019; -AACR; MAR 29-APR 3, 2019; Atlanta, Georgia, USA.
[Oral Communication]
Perakis, SO; Speicher, MR; Heitzer, E
Moving beyond DNA sequence: genome-wide profiling of plasma DNA
31st European Congress of Pathology; SEP 7-11, 2019; Nice, France. 2019.
[Oral Communication]
Ulz, P; Perakis, S; Zhou, Q; Moser, T; Belic, J; Lazzeri, I; Wölfler, A; Zebisch, A; Gerger, A; Pristauz, G; Petru, E; White, B; Roberts, C; St. John, J; Schimek, MG; Geigl, JB; Bauernhofer, T; Sill, H; Bock, C; Heitzer, E; Speicher,M
Inference of tumor cell-specific transcription factor binding from cell-free DNA enables tumor subtype prediction
Circulating Nucleic Acids in Plasma and Serum (CNAPS); SEP 23-25, 2019; Jerusalem, Israel. 2019.
[Poster]
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Belic, J; Graf, R; Bauernhofer, T; Cherkas, Y; Peter, U; Waldispuehl-Geigl, J; Perakis, S; Gormley, M; Patel, J; Li, WM; Geigl, JB; Smirnov, D; Heitzer, E; Gross, M; Speicher, MR
Analysis of circulating tumor DNA reveals genomic alterations in metastatic prostate cancer patients treated with abiraterone acetate plus prednisone or enzalutamide
CANCER RES. 2018; 78(13):-Annual Meeting of the American-Association-for-Cancer-Research (AACR); APR 14-18, 2018; Chicago, IL.
Doi: 10.1158/1538-7445.AM2018-2959
[Oral Communication]
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Lazzeri, I; Perakis, S; Moser, T; Zhou, Q; Ulz, P; Heitzer, E; Speicher, M
Patterns of aging in diverse liquid biopsy assays
Young Investigator Retreat; 1- 4, 2018; Seeboden, AUSTRIA. 2018.
[Oral Communication]
Moser, T; Ulz, P; Zhou, Q; Perakis, Samantha; Geigl, JB; Speicher, MR; Heitzer, E
Single-stranded library preparation does not preferentially enrich circulating tumor DNA.
11th International Symposium on Minimal Residual Cancer. 2018; -ISMRC; MAY 3-5, 2018; Montpellier, FRANCE.
[Poster]
Zhou, Q; Perakis, S; Ulz, P; Pichler, M; Gerger, A; Bauernhofer, T; Geigl, JB; Heitzer, E; Speicher, MR
Role of frequent chr13 q12.2 amplification in colorectal cancer patients
Role of frequent chr13 q12.2 amplification in colorectal cancer patients. 2018; -11th International Symposium on Minimal Residual Cancer; MAY 3-5, 2018; Montpellier, FRANCE.
[Poster]
Graier, T; Auer, M; Heitzer, E; Ulz, P; Perakis, S; Speicher, MR; Geigl, JB
Rapid single-cell copy-number aberration analysis using high- throughput sequencing.
EUR J CANCER. 2017; 72: S24-S24.-ECCO European Cancer Congress; JAN 27-30, 2017; Amsterdam, NETHERLANDS.
Doi: 10.1016/S0959-8049(17)30159-4
[Poster]
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Moser, T; Ulz, P; Zhou, Q; Perakis, S; Geigl, JB; Speicher, MR; Heitzer, E
Single-stranded library preparation does not preferentially enrich circulating tumor DNA.
Doctoral Day 2017; DEC 13, 2017; Graz, AUSTRIA. 2017.
[Poster]
Perakis S, Zhuo Q, Weber S, Ulz P, Geigl JB, Speicher MR and Heitzer E
Diagnostic workflows for liquid biopsy approaches
http://journals.sagepub.com/doi/full/10.1177/1010428317742551. 2017; -ISOBM 2017
; SEP 4-7, 2017; Rio de Janerio, BRASIL.
[Oral Communication]
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Ulz P, Perakis S, Zhuo Q, Moser T, Speicher MR and Heitzer E
Nucleosome positioning as cancer biomarker
https://doi.org/10.1177/1010428317742551 . 2017; -ISOBM; SEP 4-7, 2017; Rio de Janerio, BRASIL.
[Oral Communication]
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Zhou, Q; Perakis, S; Ulz, P; Pichler, M; Gerger, A; Geigl, JB; Heitzer, E; Speicher, MR
Investigation of the role of frequent chr13 q12.2 focal amplification in
colorectal cancer patients
17. Jahrestagung der Österreichischen Gesellschaft für Humangenetik (ÖGH); SEP 29, 2017; Graz, AUSTRIA . 2017.
[Oral Communication]
Heitzer, E; Perakis, S; Auer, M; Belic, J; Ulz, P; Lafer, I; Bauernhofer, T; Petru, E; Augustin, H; Geigl, JB; Speicher, MR.
Clinical Utility of Circulating Tumor DNA Monitoring: A report of more than 400 plasma-Seqs
Medizinische Genetik. 2016; -GfH Tagung ; MAR 16-18, 2016; Lübeck, GERMANY.
[Oral Communication]
Ulz, P; Heitzer, E; Auer, M; Belic, J; Perakis, S; Geigl, JB; Speicher, MR;
Krebsdiagnostik aus dem peripheren Blut: Zirkulierende Tumor DNA (ctDNA)
Forum Spital 2016, Update Onkologie; JUN 15-16, 2016; Vösendorf, AUSTRIA. 2016.
[Oral Communication]
Zhou, Q; Perakis, S; Ulz, P; Heitzer, E; Pichler,M; Gerger, A; Bauernhofer, T; Geigl, JB; Speicher, MR
Monitoring targeted therapy response by cell-free circulating tumor DNA in metastatic colorectal cancer
Doctoral day; DEC 14, 2016; Graz, Austria. 2016.
[Poster]
Rupp, VM.; Hoffmann EM; Heitzer, E; Auer, M; Ulz; P, Perakis, S; Beichler, C; Geigl, JB; Speicher,MR
A novel adenoviral system allows highly specific tumor cell detection in blood
Medizinische Genetik, March 2015, Volume 27, Issue 1, pp 79-196. 2015; 27(1):79-196.-26. Jahrestagung der Deutschen Gesellschaft für Humangenetik
gemeinsam mit der Österreichischen Gesellschaft für Humangenetik
und der Schweizerischen Gesellschaft für Medizinische Genetik; APR 15-17, 2015; Graz.
[Oral Communication]
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V. Stiegelbauer,
A. Ress,
D. Schwarzenbacher,
A. Deutsch,
S. Perakis,
H. Ling,
C. Ivan,
G. Calin,
A. Gerger,
B. Rinner and
M. Pichler
The role of the putative tumor suppressor protein spinophilin in colorectal cancer
Ann Oncol (2015) 26 (suppl 4): iv64 doi:10.1093/annonc/mdv233.216 . 2015; -ESMO World Congress on Gastrointestinal Cancer; JUL 1-4, 2015; Barcelona, Spain.
[Poster]