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Moustafa Tarek |

Presentations at scientific and public conferences

Steiner, A; Rieder, A; Strutz, J; Amtmann, B; Weiß, E; Moustafa, T; Tocantins, C; Hiden, U; Kulovic-Sissawo, A Gestational Diabetes Mellitus (GDM) Alters Umbilical Cord Blood Liver Parameters
Doctoral Day 2025; FEB 13, 2025; Graz, AUSTRIA. 2025. [Poster]

 

Steiner, A; Rieder, A; Strutz, J; Amtmann, B; Weiß, E; Moustafa, T; Tocantins, C; Hiden, U; Kulovic-Sissawo, A Gestational Diabetes Alters Neonatal GGT: Links to Neonatal Metaflammation and Metabolic Health.
European Journal of Clinical Investigation. 2025; 55(S2):81-82.-59th Annual Scientific Meeting of the European Society for Clinical Investigation; MAY 21-23, 2025; Genoa, ITALY. [Oral Communication]
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Evangelakos, I; Scheja, L; Moustafa, T; Heeren, J THE SYNTHETIC BILE ACID DERIVATIVE NORUDCA IMPAIRS MITOCHONDRIAL FUNCTION AND ADAPTIVE THERMOGENESIS
ATHEROSCLEROSIS. 2024; 395: -92nd EAS Congress; MAY 26-29, 2024; Lyon, FRANCE. [Oral Communication]
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Vargek, M; Reynders, M; Sommer, J; Silbert-Wagner, D; Fickert, P; Moustafa, T; FIBROBLAST GROWTH FACTORS 15 AND 21 ARE BOTH REQUIRED TO MAINTAIN hepatic and adipose METABOLISM
European lipoprotein club: report of the 46th ELC annual conference. Tutzing, 11–14 September 2023; Atherosclerosis 2003. 2023; -46th Annual Scientific Meeting of the European Lipoprotein Club; September 11-14, 2023; Tutzing, Germany. [Oral Communication]
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Zaufel, A; Sommer, J; Silbert-Wagner, D; Racedo, S; Fauler, G; Efeyan, A; Sun, W; Wolfrum, C; Fickert, P; Moustafa, T The lysosomal LAMTOR/Ragulator complex regulates hepatocellular metabolism and liver cell fate.
https://www.lipidmeeting.de/. 2021; -XXII LIPID MEETING ; Dez 9-11,2021; Leipzig, Deutschland. [Poster]

 

Tarek Moustafa, Tobias Madl, Dagmar Kratky, Sarah Stryeck, Thomas Eichmann, Judith Gumhold, Silvia Racedo, Dagmar Silbert, Thomas Hitch, Kern Charlotte, Anna Worthmann, Thomas Clavel, Schoonjans Kristina, Joerg Heeren, Peter Fickert and Michael Trauner Targeting biliary and microbial choline metabolism improves NAFLD and atherosclerosis in ApoE deficient animals.
https://meetings.embo.org/event/19-organ-crosstalk. 2019; -EMBO Meeting on Organ crosstalk in energy balance and metabolic disease; 08 – 11 April 2019; Spain . [Poster]

 

T. Moustafa, T. Madl, D. Kratky, S. Stryeck, T. Eichmann, J. Gumhold, S. Racedo, D. Silbert, T. Hitch, C. Kern, T. Clavel, K. Schoonjans, P. Fickert, M. Trauner Targeting host and microbial choline metabolism by a semi-synthetic bile acid suppresses TMA/TMAO formation and ameliorates atherosclerosis and NASH in mice.
http://www.falk-foundation-symposia.org/uploads/tx_tocfpshoperw/GS211e.pdf. 2018; -XXIV International Bile Acid Meeting: Bile Acids in Health and Disease; July 6–7, 2018 ; Dublin, Ireland. [Oral Communication]

 

Moustafa, T; Fickert, P Kongressbericht zum Keystone Bile Acid Receptor Meeting
Keystone Bile Acid Receptor Meeting; MAR 3-7, 2017; Monterey, USA. 2017.

 

Moustafa, T; Zaufel, A; Eichmann, T; Kolb-Lenz, D; Trauner, M; Fickert, P Regulation of the mechanistic target of rapamycin complex 1 (mTORC1) - nuclear hormone receptor signaling by bile acids
J HEPATOL. 2017; 66(1):S111-S111.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS. Doi: 10.1016/S0168-8278(17)30481-6 [Poster]
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Tarek Moustafa, Thomas Eichmann, Kathrin A. Zierler, Heimo Wolinski, Kolb Dagmar, Judith Gumhold, Peter Fickert, Michael Trauner Bile acid-dependent regulation of lysosomal biogenesis and function
XXIV International Bile Acid Meeting: Bile Acids in Health and Disease; June 17 - 18, 2016; Düsseldorf, Germany. 2016. [Poster]

 

Leithner, K; Hrzenjak, A; Trötzmüller, M; Moustafa, T; Köfeler, HC; Wohlkoenig, C; Stacher, E; Harris, AL; Olschewski, A; Olschewski, H Role of the gluconeogenic enzyme phosphoenolpyruvate carboxykinase in lung cancer
European Journal of Cancer . 2014; 50 Supplement 5: S84-S84.-23rd Biennial Congress of the European Association for Cancer Research; JULY 5-8, 2014; Munich, Germany. [Poster]

 

Leithner, K; Hrzenjak, A; Trotzmuller, M; Moustafa, T; Kofeler, HC; Wohlkoenig, C; Stacher, E; Harris, AL; Olschewski, A; Olschewski, H; Role of the gluconeogenic enzyme phosphoenolpyruvate carboxykinase in lung cancer.
EUR J CANCER. 2014; 50: S84-S84.-EACR 23; Doi: 10.1016/S0959-8049(14)50315-2 [Poster]
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Leithner, K; Hrzenjak, A; Trötzmüller, M; Moustafa, T; Köfeler, HC; Wohlkoenig, C; Stacher, E; Lindenmann, J; Harris, AL; Olschewski, A; Olschewski, H The gluconeogenic enzyme PCK2 mediates an adaptive response to glucose depletion in lung cancer
Abstract book. 2014; (X6):2015--Keystone Symposium Tumor Metabolism; March 16-21, 2014; Whistler, CANADA. [Poster]

 

Fickert, P; Silbert, D; Moustafa, T; Halilbasic, E; Krones, E; Durchschein, F; Thueringer, A; Pollheimer, MJ; Zollner, G; Denk, H; Trauner, M DIFFERENTIAL EFFECTS OF NORUDCA AND UDCA IN OBSTRUCTIVE CHOLESTASIS IN MICE
HEPATOLOGY. 2011; 54: 775A-775A.-62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 04-08, 2011; San Francisco, CA. [Poster]
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Fickert, P; Thueringer, A; Moustafa, T; Silbert, D; Yang, M; Jaeschke, H; Stokman, G; Wells, R; Eller, K; Rosenkranz, AR; Eggertsen, G; Denk, H; Trauner, M TUBULOINTERSTITIAL KIDNEY FIBROSIS AND CHRONIC RENAL FAILURE IN LONG-TERM COMMON BILE-DUCT-LIGATED MICE AS A RESULT OF COLLECTING DUCT INJURY: THE ROLE OF OSTEOPONTIN, FXR, AND CYP8B1
HEPATOLOGY. 2011; 54: 1250A-1251A.-62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 04-08, 2011; San Francisco, CA.
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Fickert, P; Thueringer, A; Moustafa, T; Yang, M; Jaeschke, H; Wells, RG; Stokman, G; Denk, H; Trauner, M LONG-TERM COMMON BILE DUCT-LIGATION IN MICE INDUCES TUBULOINTERSTITIAL KIDNEY FIBROSIS AND CHRONIC RENAL FAILURE: ROLE OF BILE ACID NUCLEAR RECEPTOR FXR AND OSTEOPONTIN
J HEPATOL. 2011; 54: S244-S244.-46th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); 2011; Berlin, GERMANY. Doi: 10.1016/S0168-8278(11)60602-8
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Fuchs, CD; Moustafa, T; Haemmerle, G; Halilbasic, E; Gumhold, J; Silbert, D; Fickert, P; Zechner, R; Trauner, M ADIPOSE TRIGLYCERIDE LIPASE (ATGL) IS A NOVEL MODULATOR OF HEPATIC ER-STRESS
J HEPATOL. 2010; 52: S305-S305.-45th Annual Meeting of the European Association for the Study of the Liver; APR 14 - 18,2010; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(10)60787-8 [Oral Communication]
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Moustafa, T; Fickert, P; Magnes, C; Frank, S; Kratky, D; Sinner, F; Gumhold, J; Silbert, D; Halsegger, S; Trauner M METABOLIC REPROGRAMMING OF LIPID METABOLISM BY THE SIDE-CHAIN MODIFIED BILE ACID, 24-NORURSODEOXYCHOLIC ACID, RESTORES INFLAMMATION-DRIVEN LIVER INJURY AND ABERRANT PROLIFERATION IN ABCB4-/- MICE
J HEPATOL. 2010; 52: S20-S21.-45th Annual Meeting of the European Association for the Study of the Liver; APR 14 - 18,2010; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(10)60049-9 [Oral Communication]
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Farzi, A; Fickert, P; Moustafa, T; Silbert, D; Trauner, M mTOR signaling in chronic cholestatic liver injury.
Book of Abstracts and Conference Proceedings of the 1st annual meeting . 2009; -ÖGMBT (Austrian Association of Molecular Life Sciences and Biotechnology) Annual Meeting ; SEP 21-23, 2009; Innsbruck, AUSTRIA. [Poster]

 

Moustafa, T; Fickert, P; Magnes, CH; Halilbasic, E; Fuchsbichler, A; Sinner, F; Fauler, G; Vesely, P; Frank, S; Kratky, D; Gumhold, J; Silbert, D; Denk, H; Guelli, CH; Trauner, M 24-norursodeoxycholic acid, a side-chain modified bile acid targets inflammation, oxidative stress and lipid metabolism in chronic liver injury.
keine2009; -ZMF & Doctoral Day; Nov, 2009; Graz, AUSTRIA. [Poster]

 

Fickert, P; Moustafa, T; Fuchsbichler, A; Claudel, T; Kratky, D; Denk, H; Trauner, M Differential effects of norUDCA and UDCA in the treatment of fatty liver disease and atherosclerosis.
keine2008; -ZMF Day; NOV, 2008; Graz, AUSTRIA. [Poster]

 

Fickert, P; Moustafa, T; Fuchsbichler, A; Claudel, T; Halilbasic, E; Zatloukal, K; Denk, H; Trauner, M Differential effects of nor UDCA and UDCA in the treatment of fatty liver and arteriosclerosis in western chow-fed ApoE knock out mice
J HEPATOL. 2008; 48: S42-S42.-Annual Meeting, EASL; April 2008; Milann, Italy. Doi: 10.1016/S0168-8278(08)60100-2 [Oral Communication]
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Moustafa, T; Fickert, P; Fuchsbichler, A; Fauler, G; Streith, I; Vesely, P; Silbert, D; Gumhold, J; Denk, H; Trauner, M Side-chain modification of Ursodeoxycholic acid alters cellular hyper-proliferation and lipid homeostasis in a mouse model of chronic cholestatic liver injury.
keine2008; -ZMF Day; NOV, 2008; Graz, AUSTRIA. [Oral Communication]

 

Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Halilbasic, E; Trauner, MH LOSS OF FXR ATTENUATES SCLEROSING CHOLANGITIS AND BILIARY FIBROSIS IN MDR2(-/-) AND FXR(-/-) DOUBLE KNOCKOUT MICE
HEPATOLOGY. 2008; 48(4):777--59th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; OCT 31-NOV 04, 2008; San Francisco, CA. [Poster]
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Moustafa, T; Halilbasic, E; Fickert, P; Fuchsbichler, A; Gumhold, J; Silbert, D; Denk, H; Trauner, M Side chain modified bile acids modulate endoplasmic reticulum stress in Mdr2(-/-) mice in vivo and bile duct epithelial cells in vitro
J HEPATOL. 2008; 48: S54-S55.-EASL Annula Meeting; April 2008; Milan Italy. Doi: 10.1016/S0168-8278(08)60127-0 [Oral Communication]
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Halilbasic, E; Fickert, P; Fuchsbichler, A; Moustafa, T; Stoeger, U; Ueno, Y; Denk, H; Trauner, M TNF alpha and LPS but not bile acids play a key role in the induction of reactive phenotype in bile duct epithelial cells in vitro
J HEPATOL. 2007; 46: S121-S121.-EASL; April 11-15, 2007; Barcelona/Spain. Doi: 10.1016/S0168-8278(07)61905-9 [Poster]
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Moustafa, T; Fickert, P; Vesely, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Denk, H; Guelly, C; Trauner, M Retention of toxic bile acids activate the mTOR, p70S6k/rps6 signaling pathway in mouse models of cholestatic liver injury
J HEPATOL. 2007; 46: S23-S23. Doi: 10.1016/S0168-8278(07)61646-8 [Oral Communication]
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Wagner, M; Moustafa, T; Fickert, P; Zollner, G; Gumhold, J; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Absence of FXR protects mice from bile-infarcts in biliary obstruction by reduction of bile acid-independent bile flow: Implications for targeting FXR in treatment of cholestasis?
J HEPATOL. 2007; 46: S5-S5.-42th Annual Meeting, European Association for the Study of the Liver; April, 11-15, 2007; Barcelona, Spain. Doi: 10.1016/S0168-8278(07)61603-1 [Oral Communication]
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Moustafa, T; Fickert, P; Fuchsbichler, A; Vesely, P; Silbert, D; Gumhold, J; Denk, H; Guelly, CH; Trauner, M he side-chain shortened bile acid 24-norUDCA reverses biliary fibrosis and alters cellular hyperproliferation in a mouse model of chronic cholestatic liver injury.
keine2006; -ZMF Day; NOV, 2006; Graz, AUSTRIA. [Oral Communication]

 

Moustafa, T; Fickert, P; Guelly, C; Silbert, D; Gumhold, J; Fuchsbichler, A; Denk, H; Trauner, M Transcriptional profiling of Mdr2 knockout (Mdr2-/-) mice treated with nor-UDCA reveals global anti-inflammatory and anti-fibrotic effects
J HEPATOL. 2006; 44: S42-S42.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(06)80095-4 [Poster]
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Moustafa, T; Fickert, P; Guelly, C; Silbert, D; Gumhold, J; Fuchsbichler, A; Denk, H; Trauner, M 24-nor-ursodeoxycholic acid abolishes enhanced cellular proliferation in Mdr2 (abcb4) knockout mice by modulation of mTOR, p70s6k and rps6 signaling
HEPATOLOGY. 44(4):602A-603A. [Poster]
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Moustafa, T; Fickert, P; Kratky, D; Prokesch, A; Trajanoski, Z; Trauner, M The nuclear bile acid receptor FXR is required to balance intra-hepatic lipid synthesis, storage and utilization in a mouse model of cholestatic liver injury.
keine2006; -Keystone Symposium; JAN, 2006; Colorado, USA. [Poster]

 

Moustafa, T; Fickert, P; Prokesch, A; Wagner, M; Fuchsbichler, A; Silbert, D; Gumhold, J; Denk, H; Trajanoski, Z; Trauner, M Common bile-duct-ligation of FXR knockout mice results in severe hepatic steatosis due to enhancement in lipogenic gene expression
J HEPATOL. 44: S28-S28.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(06)80063-2 [Poster]
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Stoger, U; Fickert, P; Fuchsbichler, A; Moustafa, T; Gumhold, J; Silbert, D; Zatlouka, K; Denk, H; Trauner, M 3.5-diethoxycarbonyl-1.4-dihydrocollidine (DDC) feeding induces cholestasis, chronic inflammatory bile duct damage and biliary fibrosis in mice
J HEPATOL. 44: S123-S124.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(06)80321-1 [Poster]
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Zollner, G; Wagner, M; Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Helmut, D; Marschall, HU; Trauner, M Role of nuclear bile acid receptor FXR in regulation of bile acid detoxification and organic solute transporter (OST-alpha/beta) expression in bile acid-fed mice
J HEPATOL. 44: S124-S124.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(06)80322-3 [Poster]
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Panzitt, K; Strohmaier, HM; Moustafa, T; Stradner, M; Gully, C; Buck, CR; Denk, H; Zatloukal, K A non-protein-coding RNA is a major deregulated gene in hepatocellular carcinoma and may act as a general modulator of gene expression
HEPATOLOGY 2004 40: 253A-253A.
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Strohmaier, HM; Panzitt, K; Moustafa, T; Stradner, M; Gülly, C; Buck, CR; Zatloukal, K A novel non-coding RNA implicated in liver cancer.
Proceedings of the 95th Annual Meeting of the American Association for Cancer Research. 2004; -95th Annual Meeting of the American Association for Cancer Research; MAR 27-31, 2004; Orlando, FL, USA. [Poster]

 

Panzitt, K; Moustafa, T; Stradner, M; Guelly, C; Strohmaier, H; Buck, CR; Zatloukal, K Non-coding RNA in disease.
Jahrestagung der ÖGBM, ÖGGGT und ANGT; SEP 21-24, 2003; Graz, AUSTRIA. 2003. [Poster]

 

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