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1234 Publikationen des Forschungsfeldes "Molekulare Grundlagen Lipid-assoziierter Erkrankungen (Beendet 2020)":

2021

Vujić, N; Bradić, I; Goeritzer, M; Kuentzel, KB; Rainer, S; Kratky, D; Radović, B ATG7 is dispensable for LC3-PE conjugation in thioglycolate-elicited mouse peritoneal macrophages.
Autophagy. 2021; 17(11):3402-3407 Doi: 10.1080/15548627.2021.1874132 [OPEN ACCESS]
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Dalkner, N; Bengesser, S; Birner, A; Rieger, A; Seebauer, J; Platzer, M; Hamm, C; Maget, A; Queissner, R; Pilz, R; Fellendorf, FT; Reininghaus, B; Strassnig, MT; Kapfhammer, HP; Weiss, EM; Reininghaus, EZ Body Mass Index Predicts Decline in Executive Function in Bipolar Disorder: Preliminary Data of a 12-Month Follow-up Study.
Neuropsychobiology. 2021; 80(1):1-11 Doi: 10.1159/000505784
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Knuplez, E; Kienzl, M; Trakaki, A; Schicho, R; Heinemann, A; Sturm, EM; Marsche, G The anti-parasitic drug miltefosine suppresses activation of human eosinophils and ameliorates allergic inflammation in mice.
Br J Pharmacol. 2021; 178(5):1234-1248 Doi: 10.1111/bph.15368 [OPEN ACCESS]
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Züllig, T; Köfeler, HC HIGH RESOLUTION MASS SPECTROMETRY IN LIPIDOMICS.
Mass Spectrom Rev. 2021; 40(3):162-176 Doi: 10.1002/mas.21627 [OPEN ACCESS]
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Wunderling, K; Leopold, C; Jamitzky, I; Yaghmour, M; Zink, F; Kratky, D; Thiele, C Hepatic synthesis of triacylglycerols containing medium-chain fatty acids is dominated by diacylglycerol acyltransferase 1 and efficiently inhibited by etomoxir.
Mol Metab. 2020; 45: 101150-101150. Doi: 10.1016/j.molmet.2020.101150 [OPEN ACCESS]
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Panzitt, K; Fickert, P; Wagner, M Regulation of autophagy by bile acids and in cholestasis - CholestoPHAGY or CholeSTOPagy.
Biochim Biophys Acta Mol Basis Dis. 2021; 1867(2):166017-166017 Doi: 10.1016/j.bbadis.2020.166017
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Schilcher, I; Stadler, JT; Lechleitner, M; Hrzenjak, A; Berghold, A; Pregartner, G; Lhomme, M; Holzer, M; Korbelius, M; Reichmann, F; Springer, A; Wadsack, C; Madl, T; Kratky, D; Kontush, A; Marsche, G; Frank, S Endothelial Lipase Modulates Paraoxonase 1 Content and Arylesterase Activity of HDL.
Int J Mol Sci. 2021; 22(2): Doi: 10.3390/ijms22020719 [OPEN ACCESS]
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Luan, W; Hao, CZ; Li, JQ; Wei, Q; Gong, JY; Qiu, YL; Lu, Y; Shen, CH; Xia, Q; Xie, XB; Zhang, MH; Abuduxikuer, K; Li, ZD; Wang, L; Xing, QH; Knisely, AS; Wang, JS Biallelic loss-of-function ZFYVE19 mutations are associated with congenital hepatic fibrosis, sclerosing cholangiopathy and high-GGT cholestasis.
J Med Genet. 2021; 58(8):514-525 Doi: 10.1136/jmedgenet-2019-106706
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Fallah, S; Marsche, G; Mohamadinarab, M; Mohassel Azadi, S; Ghasri, H; Fadaei, R; Moradi, N Impaired cholesterol efflux capacity in patients with Helicobacter pylori infection and its relation with inflammation.
J Clin Lipidol. 2020; 15(1):218-226 Doi: 10.1016/j.jacl.2020.11.005
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Stadler, JT; Lackner, S; Mörkl, S; Trakaki, A; Scharnagl, H; Borenich, A; Wonisch, W; Mangge, H; Zelzer, S; Meier-Allard, N; Holasek, SJ; Marsche, G Obesity Affects HDL Metabolism, Composition and Subclass Distribution.
Biomedicines. 2021; 9(3): Doi: 10.3390/biomedicines9030242 [OPEN ACCESS]
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Knisely, AS; Houwen, RHJ Liver Steatosis and Diarrhea After Liver Transplantation for Progressive Familial Intrahepatic Cholestasis Type 1: Can Biliary Diversion Solve These Problems?
J Pediatr Gastroenterol Nutr. 2021; 72(3):341-342 Doi: 10.1097/MPG.0000000000002990
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Aengenheister, L; Favaro, RR; Morales-Prieto, DM; Furer, LA; Gruber, M; Wadsack, C; Markert, UR; Buerki-Thurnherr, T Research on nanoparticles in human perfused placenta: State of the art and perspectives.
Placenta. 2021; 104:199-207 Doi: 10.1016/j.placenta.2020.12.014 [OPEN ACCESS]
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Traussnigg, S; Halilbasic, E; Hofer, H; Munda, P; Stojakovic, T; Fauler, G; Kashofer, K; Krssak, M; Wolzt, M; Trauner, M Open-label phase II study evaluating safety and efficacy of the non-steroidal farnesoid X receptor agonist PX-104 in non-alcoholic fatty liver disease.
Wien Klin Wochenschr. 2021; 133(9-10):441-451 Doi: 10.1007/s00508-020-01735-5 [OPEN ACCESS]
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Niedrist, T; Mangge, H; Herrman, M Comparison of Automated Procalcitonin Immunoassays under Routine Conditions.
Clin Lab. 2021; 67(1): Doi: 10.7754/Clin.Lab.2020.200457
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2020

Kleber, ME; Delgado, GE; März, W LDL receptor traffic: in the fast lane.
Eur Heart J. 2020; 41(9):1054-1056 Doi: 10.1093/eurheartj/ehz866
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Paschoal, VA; Walenta, E; Talukdar, S; Pessentheiner, AR; Osborn, O; Hah, N; Chi, TJ; Tye, GL; Armando, AM; Evans, RM; Chi, NW; Quehenberger, O; Olefsky, JM; Oh, DY Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin Sensitivity.
Cell Metab. 2020; 31(6): 1173-1188. Doi: 10.1016/j.cmet.2020.04.020 [OPEN ACCESS]
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Smole, U; Gour, N; Phelan, J; Hofer, G; Köhler, C; Kratzer, B; Tauber, PA; Xiao, X; Yao, N; Dvorak, J; Caraballo, L; Puerta, L; Rosskopf, S; Chakir, J; Malle, E; Lane, AP; Pickl, WF; Lajoie, S; Wills-Karp, M Serum amyloid A is a soluble pattern recognition receptor that drives type 2 immunity.
Nat Immunol. 2020; 21(7):756-765 Doi: 10.1038/s41590-020-0698-1 [OPEN ACCESS]
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Zewinger, S; Reiser, J; Jankowski, V; Alansary, D; Hahm, E; Triem, S; Klug, M; Schunk, SJ; Schmit, D; Kramann, R; Körbel, C; Ampofo, E; Laschke, MW; Selejan, SR; Paschen, A; Herter, T; Schuster, S; Silbernagel, G; Sester, M; Sester, U; Aßmann, G; Bals, R; Kostner, G; Jahnen-Dechent, W; Menger, MD; Rohrer, L; März, W; Böhm, M; Jankowski, J; Kopf, M; Latz, E; Niemeyer, BA; Fliser, D; Laufs, U; Speer, T Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation.
Nat Immunol. 2020; 21(1): 30-41. Doi: 10.1038/s41590-019-0548-1
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Norel, X; Sugimoto, Y; Ozen, G; Abdelazeem, H; Amgoud, Y; Bouhadoun, A; Bassiouni, W; Goepp, M; Mani, S; Manikpurage, HD; Senbel, A; Longrois, D; Heinemann, A; Yao, C; Clapp, LH International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E₂ Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions.
Pharmacol Rev. 2020; 72(4): 910-968. Doi: 10.1124/pr.120.019331 [OPEN ACCESS]
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Panzitt, K; Jungwirth, E; Krones, E; Lee, JM; Pollheimer, M; Thallinger, GG; Kolb-Lenz, D; Xiao, R; Thorell, A; Trauner, M; Fickert, P; Marschall, HU; Moore, DD; Wagner, M FXR-dependent Rubicon induction impairs autophagy in models of human cholestasis.
J Hepatol. 2020; 72(6):1122-1131 Doi: 10.1016/j.jhep.2020.01.014 [OPEN ACCESS]
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Trieb, M; Rainer, F; Stadlbauer, V; Douschan, P; Horvath, A; Binder, L; Trakaki, A; Knuplez, E; Scharnagl, H; Stojakovic, T; Heinemann, Á; Mandorfer, M; Paternostro, R; Reiberger, T; Pitarch, C; Amorós, A; Gerbes, A; Caraceni, P; Alessandria, C; Moreau, R; Clària, J; Marsche, G; Stauber, RE HDL-related biomarkers are robust predictors of survival in patients with chronic liver failure.
J Hepatol. 2020; 73(1):113-120 Doi: 10.1016/j.jhep.2020.01.026 [OPEN ACCESS]
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Pfeil, EM; Brands, J; Merten, N; Vögtle, T; Vescovo, M; Rick, U; Albrecht, IM; Heycke, N; Kawakami, K; Ono, Y; Ngako Kadji, FM; Hiratsuka, S; Aoki, J; Häberlein, F; Matthey, M; Garg, J; Hennen, S; Jobin, ML; Seier, K; Calebiro, D; Pfeifer, A; Heinemann, A; Wenzel, D; König, GM; Nieswandt, B; Fleischmann, BK; Inoue, A; Simon, K; Kostenis, E Heterotrimeric G Protein Subunit Gαq Is a Master Switch for Gβγ-Mediated Calcium Mobilization by Gi-Coupled GPCRs.
Mol Cell. 2020; 80(6):940-954 Doi: 10.1016/j.molcel.2020.10.027
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Choi, S; Dong, B; Lin, CJ; Heo, MJ; Kim, KH; Sun, Z; Wagner, M; Putluri, N; Suh, JM; Wang, MC; Moore, DD Methyl-Sensing Nuclear Receptor Liver Receptor Homolog-1 Regulates Mitochondrial Function in Mouse Hepatocytes.
Hepatology. 2020; 71(3):1055-1069 Doi: 10.1002/hep.30884 [OPEN ACCESS]
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Tardelli, M; Bruschi, FV; Fuchs, CD; Claudel, T; Auer, N; Kunczer, V; Baumgartner, M; Ronda, OAHO; Jan Verkade, H; Stojakovic, T; Scharnagl, H; Habib, A; Zimmermann, R; Lotersztajn, S; Trauner, M Monoacylglycerol lipase inhibition protects from liver injury in mouse models of sclerosing cholangitis.
Hepatology. 2020; Doi: 10.1002/hep.30929 [OPEN ACCESS]
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Alexopoulos, SJ; Chen, SY; Brandon, AE; Salamoun, JM; Byrne, FL; Garcia, CJ; Beretta, M; Olzomer, EM; Shah, DP; Philp, AM; Hargett, SR; Lawrence, RT; Lee, B; Sligar, J; Carrive, P; Tucker, SP; Philp, A; Lackner, C; Turner, N; Cooney, GJ; Santos, WL; Hoehn, KL Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice.
Nat Commun. 2020; 11(1):2397-2397 Doi: 10.1038/s41467-020-16298-2 [OPEN ACCESS]
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Wagner, M; Fickert, P Drug Therapies for Chronic Cholestatic Liver Diseases.
Annu Rev Pharmacol Toxicol. 2020; 60(1):503-527 Doi: 10.1146/annurev-pharmtox-010818-021059
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Roula, D; Theiler, A; Luschnig, P; Sturm, GJ; Tomazic, PV; Marsche, G; Heinemann, A; Sturm, EM Apolipoprotein A-IV acts as an endogenous anti-inflammatory protein and is reduced in treatment-naïve allergic patients and allergen-challenged mice.
Allergy. 2020; 75(2):392-402 Doi: 10.1111/all.14022 [OPEN ACCESS]
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Heine, GH; Eller, K; Stadler, JT; Rogacev, KS; Marsche, G, ;RITERM, study, group;RITERM, study, group Lipid-modifying therapy in chronic kidney disease: Pathophysiological and clinical considerations.
Pharmacol Ther. 2020; 207:107459 Doi: 10.1016/j.pharmthera.2019.107459
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Sladky, VC; Knapp, K; Soratroi, C; Heppke, J; Eichin, F; Rocamora-Reverte, L; Szabo, TG; Bongiovanni, L; Westendorp, B; Moreno, E; van Liere, EA; Bakker, B; Spierings, DCJ; Wardenaar, R; Pereyra, D; Starlinger, P; Schultze, S; Trauner, M; Stojakovic, T; Scharnagl, H; Fava, LL; Foijer, F; de Bruin, A; Villunger, A E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration.
Dev Cell. 2020; 52(3):335-349 Doi: 10.1016/j.devcel.2019.12.016
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Bärnthaler, T; Theiler, A; Zabini, D; Trautmann, S; Stacher-Priehse, E; Lanz, I; Klepetko, W; Sinn, K; Flick, H; Scheidl, S; Thomas, D; Olschewski, H; Kwapiszewska, G; Schuligoi, R; Heinemann, A Inhibiting eicosanoid degradation exerts antifibrotic effects in a pulmonary fibrosis mouse model and human tissue.
J Allergy Clin Immunol. 2020; 145(3):818-833 Doi: 10.1016/j.jaci.2019.11.032 [OPEN ACCESS]
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Kolleritsch, S; Kien, B; Schoiswohl, G; Diwoky, C; Schreiber, R; Heier, C; Maresch, LK; Schweiger, M; Eichmann, TO; Stryeck, S; Krenn, P; Tomin, T; Schittmayer, M; Kolb, D; Rülicke, T; Hoefler, G; Wolinski, H; Madl, T; Birner-Gruenberger, R; Haemmerle, G Low cardiac lipolysis reduces mitochondrial fission and prevents lipotoxic heart dysfunction in Perilipin 5 mutant mice.
Cardiovasc Res. 2020; 116(2):339-352 Doi: 10.1093/cvr/cvz119 [OPEN ACCESS]
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Streidl, T; Karkossa, I; Segura, Muñoz, RR; Eberl, C; Zaufel, A; Plagge, J; Schmaltz, R; Schubert, K; Basic, M; Schneider, KM; Afify, M; Trautwein, C; Tolba, R; Stecher, B; Doden, HL; Ridlon, JM; Ecker, J; Moustafa, T; von, Bergen, M; Ramer-Tait, AE; Clavel, T The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice.
GUT MICROBES. 2020; 13(1): 1-21. Doi: 10.1080/19490976.2020.1854008 [OPEN ACCESS]
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Cantalupo, A; Sasset, L; Gargiulo, A; Rubinelli, L; Del Gaudio, I; Benvenuto, D; Wadsack, C; Jiang, XC; Bucci, MR; Di Lorenzo, A Endothelial Sphingolipid De Novo Synthesis Controls Blood Pressure by Regulating Signal Transduction and NO via Ceramide.
Hypertension. 2020; 75(5):1279-1288 Doi: 10.1161/HYPERTENSIONAHA.119.14507 [OPEN ACCESS]
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Sladky, VC; Knapp, K; Szabo, TG; Braun, VZ; Bongiovanni, L; van den Bos, H; Spierings, DC; Westendorp, B; Curinha, A; Stojakovic, T; Scharnagl, H; Timelthaler, G; Tsuchia, K; Pinter, M; Semmler, G; Foijer, F; de Bruin, A; Reiberger, T; Rohr-Udilova, N; Villunger, A PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis.
EMBO Rep. 2020; 21(12):e50893-e50893 Doi: 10.15252/embr.202050893 [OPEN ACCESS]
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Plastira, I; Bernhart, E; Joshi, L; Koyani, CN; Strohmaier, H; Reicher, H; Malle, E; Sattler, W MAPK signaling determines lysophosphatidic acid (LPA)-induced inflammation in microglia.
J Neuroinflammation. 2020; 17(1): 127-127. Doi: 10.1186/s12974-020-01809-1 [OPEN ACCESS]
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Dong, J; He, M; Li, J; Pessentheiner, A; Wang, C; Zhang, J; Sun, Y; Wang, WT; Zhang, Y; Liu, J; Wang, SC; Huang, PH; Gordts, PL; Yuan, ZY; Tsimikas, S; Shyy, JY microRNA-483 ameliorates hypercholesterolemia by inhibiting PCSK9 production.
JCI Insight. 2020; 5(23): Doi: 10.1172/jci.insight.143812 [OPEN ACCESS]
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Gutiérrez, T; Qi, H; Yap, MC; Tahbaz, N; Milburn, LA; Lucchinetti, E; Lou, PH; Zaugg, M; LaPointe, PG; Mercier, P; Overduin, M; Bischof, H; Burgstaller, S; Malli, R; Ballanyi, K; Shuai, J; Simmen, T The ER chaperone calnexin controls mitochondrial positioning and respiration.
Sci Signal. 2020; 13(638): Doi: 10.1126/scisignal.aax6660
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Gerndt, S; Chen, CC; Chao, YK; Yuan, Y; Burgstaller, S; Scotto, Rosato, A; Krogsaeter, E; Urban, N; Jacob, K; Nguyen, ONP; Miller, MT; Keller, M; Vollmar, AM; Gudermann, T; Zierler, S; Schredelseker, J; Schaefer, M; Biel, M; Malli, R; Wahl-Schott, C; Bracher, F; Patel, S; Grimm, C Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function.
Elife. 2020; 9: Doi: 10.7554/eLife.54712 [OPEN ACCESS]
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Koyani, CN; Plastira, I; Sourij, H; Hallström, S; Schmidt, A; Rainer, PP; Bugger, H; Frank, S; Malle, E; von, Lewinski, D Empagliflozin protects heart from inflammation and energy depletion via AMPK activation.
Pharmacol Res. 2020; 158:104870 Doi: 10.1016/j.phrs.2020.104870
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Pessentheiner, AR; Ducasa, GM; Gordts, PLSM Proteoglycans in Obesity-Associated Metabolic Dysfunction and Meta-Inflammation.
Front Immunol. 2020; 11(23): 769-769. Doi: 10.3389/fimmu.2020.00769 [OPEN ACCESS]
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Hartler, J; Armando, AM; Trötzmüller, M; Dennis, EA; Köfeler, HC; Quehenberger, O
Anal Chem. 2020; 92(20):14054-14062 Doi: 10.1021/acs.analchem.0c03016 [OPEN ACCESS]
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Lajin, B; Goessler, W Fluoroalkylamines: Novel, Highly Volatile, Fast-Equilibrating, and Electrospray Ionization-Mass Spectrometry Signal-Enhancing Cationic Ion-Interaction Reagents.
Anal Chem. 2020; 92(14): 10121-10128. Doi: 10.1021/acs.analchem.0c02138 [OPEN ACCESS]
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Lajin, B; Goessler, W Simultaneous Determination of Chlorinated and Brominated Acetic Acids in Various Environmental Water Matrixes by High-Performance Liquid Chromatography-Inductively Coupled Plasma Tandem Mass Spectrometry without Sample Preparation.
Anal Chem. 2020; 92(13): 9156-9163. Doi: 10.1021/acs.analchem.0c01456 [OPEN ACCESS]
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Lajin, B; Goessler, W HPLC-ICPMS/MS shows a significant advantage over HPLC-ICPMS for the determination of perchlorate in ground, tap, and river water.
Anal Chim Acta. 2020; 1094(13): 11-17. Doi: 10.1016/j.aca.2019.09.070
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Tupova, L; Hirschmugl, B; Sucha, S; Pilarova, V; Székely, V; Bakos, É; Novakova, L; Özvegy-Laczka, C; Wadsack, C; Ceckova, M Interplay of drug transporters P-glycoprotein (MDR1), MRP1, OATP1A2 and OATP1B3 in passage of maraviroc across human placenta.
Biomed Pharmacother. 2020; 129(11):110506-110506 Doi: 10.1016/j.biopha.2020.110506 [OPEN ACCESS]
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Zwickl, H; Hackner, K; Köfeler, H; Krzizek, EC; Muqaku, B; Pils, D; Scharnagl, H; Solheim, TS; Zwickl-Traxler, E; Pecherstorfer, M Reduced LDL-Cholesterol and Reduced Total Cholesterol as Potential Indicators of Early Cancer in Male Treatment-Naïve Cancer Patients With Pre-cachexia and Cachexia.
Front Oncol. 2020; 10(9):1262-1262 Doi: 10.3389/fonc.2020.01262 [OPEN ACCESS]
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Ritsch, A; Duerr, A; Kahler, P; Hunjadi, M; Stojakovic, T; Silbernagel, G; Scharnagl, H; Kleber, ME; März, W Cholesterol Efflux Capacity and Cardiovascular Disease: The Ludwigshafen Risk and Cardiovascular Health (LURIC) Study.
Biomedicines. 2020; 8(11): Doi: 10.3390/biomedicines8110524 [OPEN ACCESS]
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Trakaki, A; Marsche, G High-Density Lipoprotein (HDL) in Allergy and Skin Diseases: Focus on Immunomodulating Functions.
Biomedicines. 2020; 8(12): Doi: 10.3390/biomedicines8120558 [OPEN ACCESS]
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Del Gaudio, I; Sasset, L; Lorenzo, AD; Wadsack, C Sphingolipid Signature of Human Feto-Placental Vasculature in Preeclampsia.
Int J Mol Sci. 2020; 21(3): Doi: 10.3390/ijms21031019 [OPEN ACCESS]
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Gaudio, ID; Hendrix, S; Christoffersen, C; Wadsack, C Neonatal HDL Counteracts Placental Vascular Inflammation via S1P-S1PR1 Axis.
Int J Mol Sci. 2020; 21(3): Doi: 10.3390/ijms21030789 [OPEN ACCESS]
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Goeritzer, M; Bernhart, E; Plastira, I; Reicher, H; Leopold, C; Eichmann, TO; Rechberger, G; Madreiter-Sokolowski, CT; Prasch, J; Eller, P; Graier, WF; Kratky, D; Malle, E; Sattler, W Myeloperoxidase and Septic Conditions Disrupt Sphingolipid Homeostasis in Murine Brain Capillaries In Vivo and Immortalized Human Brain Endothelial Cells In Vitro.
Int J Mol Sci. 2020; 21(3): Doi: 10.3390/ijms21031143 [OPEN ACCESS]
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Kienzl, M; Kargl, J; Schicho, R The Immune Endocannabinoid System of the Tumor Microenvironment.
Int J Mol Sci. 2020; 21(23): Doi: 10.3390/ijms21238929 [OPEN ACCESS]
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Knuplez, E; Marsche, G An Updated Review of Pro- and Anti-Inflammatory Properties of Plasma Lysophosphatidylcholines in the Vascular System.
Int J Mol Sci. 2020; 21(12): Doi: 10.3390/ijms21124501 [OPEN ACCESS]
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Prasch, J; Bernhart, E; Reicher, H; Kollroser, M; Rechberger, GN; Koyani, CN; Trummer, C; Rech, L; Rainer, PP; Hammer, A; Malle, E; Sattler, W Myeloperoxidase-Derived 2-Chlorohexadecanal Is Generated in Mouse Heart during Endotoxemia and Induces Modification of Distinct Cardiomyocyte Protein Subsets In Vitro.
Int J Mol Sci. 2020; 21(23): Doi: 10.3390/ijms21239235 [OPEN ACCESS]
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Stadler, JT; Marsche, G Obesity-Related Changes in High-Density Lipoprotein Metabolism and Function.
Int J Mol Sci. 2020; 21(23): Doi: 10.3390/ijms21238985 [OPEN ACCESS]
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Grabner, GF; Fawzy, N; Schreiber, R; Pusch, LM; Bulfon, D; Koefeler, H; Eichmann, TO; Lass, A; Schweiger, M; Marsche, G; Schoiswohl, G; Taschler, U; Zimmermann, R Metabolic regulation of the lysosomal cofactor bis(monoacylglycero)phosphate in mice.
J Lipid Res. 2020; 61(7):995-1003 Doi: 10.1194/jlr.RA119000516 [OPEN ACCESS]
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Liebisch, G; Fahy, E; Aoki, J; Dennis, EA; Durand, T; Ejsing, CS; Fedorova, M; Feussner, I; Griffiths, WJ; Kofeler, H; Merrill, AH; Murphy, RC; O'Donnell, VB; Oskolkova, O; Subramaniam, S; Wakelam, MJO; Spener, F Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures.
J LIPID RES. 2020; 61(12): 1539-1555. Doi: 10.1194/jlr.S120001025 [OPEN ACCESS]
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Schittmayer, M; Vujic, N; Darnhofer, B; Korbelius, M; Honeder, S; Kratky, D; Birner-Gruenberger, R Spatially Resolved Activity-based Proteomic Profiles of the Murine Small Intestinal Lipases.
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Zhang, J; Yang, Y; Gong, JY; Li, LT; Li, JQ; Zhang, MH; Lu, Y; Xie, XB; Hong, YR; Yu, Z; Knisely, AS; Wang, JS Low-GGT intrahepatic cholestasis associated with biallelic USP53 variants: Clinical, histological and ultrastructural characterization.
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Wackerlig, J; Köfeler, HC; Korz, V; Hussein, AM; Feyissa, DD; Höger, H; Urban, E; Langer, T; Lubec, G; Lubec, J Differences in Hypothalamic Lipid Profiles of Young and Aged Male Rats With Impaired and Unimpaired Spatial Cognitive Abilities and Memory.
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Safari, Z; Bruneau, A; Monnoye, M; Mariadassou, M; Philippe, C; Zatloukal, K; Gérard, P Murine Genetic Background Overcomes Gut Microbiota Changes to Explain Metabolic Response to High-Fat Diet.
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Silbernagel, G; Scharnagl, H; Kleber, ME; Hoffmann, MM; Delgado, G; Stojakovic, T; Gary, T; Zeng, L; Ritsch, A; Zewinger, S; Speer, T; Schunkert, H; Landmesser, U; März, W; Grammer, TB, ;Meta-Analyses, of, Glucose, and, Insulin-related, traits, Consortium, (MAGIC);Meta-Analyses, of, Glucose, and, Insulin-related, traits, Consortium, (MAGIC) Common APOC3 variants are associated with circulating ApoC-III and VLDL cholesterol but not with total apolipoprotein B and coronary artery disease.
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Vujić, N; Korbelius, M; Sachdev, V; Rainer, S; Zimmer, A; Huber, A; Radović, B; Kratky, D Intestine-specific DGAT1 deficiency improves atherosclerosis in apolipoprotein E knockout mice by reducing systemic cholesterol burden.
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Knuplez, E; Krier-Burris, R; Cao, Y; Marsche, G; O'Sullivan, J; Bochner, BS Frontline Science: Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls.
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Valencak, TG; Spenlingwimmer, T; Nimphy, R; Reinisch, I; Hoffman, JM; Prokesch, A Challenging a "Cushy" Life: Potential Roles of Thermogenesis and Adipose Tissue Adaptations in Delayed Aging of Ames and Snell Dwarf Mice.
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Züllig, T; Zandl-Lang, M; Trötzmüller, M; Hartler, J; Plecko, B; Köfeler, HC A Metabolomics Workflow for Analyzing Complex Biological Samples Using a Combined Method of Untargeted and Target-List Based Approaches.
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Marsche, G; Heine, GH; Stadler, JT; Holzer, M Current Understanding of the Relationship of HDL Composition, Structure and Function to Their Cardioprotective Properties in Chronic Kidney Disease.
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Zhang, J; Liu, LL; Gong, JY; Hao, CZ; Qiu, YL; Lu, Y; Feng, JY; Li, JQ; Li, ZD; Wang, MX; Xing, QH; Knisely, AS; Wang, JS TJP2 hepatobiliary disorders: Novel variants and clinical diversity.
Hum Mutat. 2020; 41(2):502-511 Doi: 10.1002/humu.23947
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Olivieri, O; Speziali, G; Castagna, A; Pattini, P; Udali, S; Pizzolo, F; Liesinger, L; Gindlhuber, J; Tomin, T; Schittmayer, M; Birner-Gruenberger, R; Cecconi, D; Girelli, D; Friso, S; Martinelli, N The Positive Association between Plasma Myristic Acid and ApoCIII Concentrations in Cardiovascular Disease Patients Is Supported by the Effects of Myristic Acid in HepG2 Cells.
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Lajin, B; Goessler, W Fluorinated carboxylic acids as "ion repelling agents" in reversed-phase chromatography.
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Del Gaudio, I; Sreckovic, I; Zardoya-Laguardia, P; Bernhart, E; Christoffersen, C; Frank, S; Marsche, G; Illanes, SE; Wadsack, C Circulating cord blood HDL-S1P complex preserves the integrity of the feto-placental vasculature.
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Knuplez, E; Curcic, S; Theiler, A; Bärnthaler, T; Trakaki, A; Trieb, M; Holzer, M; Heinemann, A; Zimmermann, R; Sturm, EM; Marsche, G Lysophosphatidylcholines inhibit human eosinophil activation and suppress eosinophil migration in vivo.
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Wagner, C; Hois, V; Pajed, L; Pusch, LM; Wolinski, H; Trauner, M; Zimmermann, R; Taschler, U; Lass, A Lysosomal acid lipase is the major acid retinyl ester hydrolase in cultured human hepatic stellate cells but not essential for retinyl ester degradation.
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Xie, H; Heier, C; Kien, B; Vesely, PW; Tang, Z; Sexl, V; Schoiswohl, G; Strießnig-Bina, I; Hoefler, G; Zechner, R; Schweiger, M Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling.
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Wagner, J; Knaier, R; Königstein, K; Klenk, C; Carrard, J; Lichtenstein, E; Scharnagl, H; März, W; Hanssen, H; Hinrichs, T; Schmidt-Trucksäss, A; Arbeev, K Composite Measures of Physical Fitness to Discriminate Between Healthy Aging and Heart Failure: The COmPLETE Study.
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Kienzl, M; Storr, M; Schicho, R Cannabinoids and Opioids in the Treatment of Inflammatory Bowel Diseases.
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Trakaki, A; Scharnagl, H; Trieb, M; Holzer, M; Hinghofer-Szalkay, H; Goswami, N; Marsche, G Prolonged bedrest reduces plasma high-density lipoprotein levels linked to markedly suppressed cholesterol efflux capacity.
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Vogel, GF; Maurer, E; Entenmann, A; Straub, S; Knisely, AS; Janecke, AR; Müller, T Co-existence of ABCB11 and DCDC2 disease: Infantile cholestasis requires both next-generation sequencing and clinical-histopathologic correlation.
Eur J Hum Genet. 2020; 28(6):840-844 Doi: 10.1038/s41431-020-0613-0 [OPEN ACCESS]
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Trummer, O; Schweighofer, N; Haudum, CW; Trummer, C; Pilz, S; Theiler-Schwetz, V; Keppel, MH; Grübler, M; Pieber, TR; Renner, W; Obermayer-Pietsch, B; Lerchbaum, E Genetic Components of 25-Hydroxyvitamin D Increase in Three Randomized Controlled Trials.
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Katzmann, JL; Werner, CM; Stojakovic, T; März, W; Scharnagl, H; Laufs, U Apolipoprotein CIII predicts cardiovascular events in patients with coronary artery disease: a prospective observational study.
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Leskelä, J; Pietiäinen, M; Safer, A; Lehto, M; Metso, J; Malle, E; Buggle, F; Becher, H; Sundvall, J; Grau, AJ; Pussinen, PJ; Palm, F Serum lipopolysaccharide neutralizing capacity in ischemic stroke.
PLoS One. 2020; 15(2): e0228806-e0228806. Doi: 10.1371/journal.pone.0228806 [OPEN ACCESS]
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Delgado, GE; Krämer, BK; Scharnagl, H; Fauler, G; Stojakovic, T; März, W; Kleber, ME; Lammert, A Bile Acids in Patients with Uncontrolled Type 2 Diabetes Mellitus - The Effect of Two Days of Oatmeal Treatment.
Exp Clin Endocrinol Diabetes. 2020; 128(9):624-630 Doi: 10.1055/a-1069-7330
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Dezsőfi, A; Knisely, AS Liver Biopsy in High-risk Children: Which Way to Go?
J Pediatr Gastroenterol Nutr. 2020; 70(4):411-412 Doi: 10.1097/MPG.0000000000002620
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Schmidt, N; Klose, G; Schatz, U; Laufs, U; Marz, W Familial Hypercholesterolemia in Germany.
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Zhu, XG; Nicholson Puthenveedu, S; Shen, Y; La, K; Ozlu, C; Wang, T; Klompstra, D; Gultekin, Y; Chi, J; Fidelin, J; Peng, T; Molina, H; Hang, HC; Min, W; Birsoy, K CHP1 Regulates Compartmentalized Glycerolipid Synthesis by Activating GPAT4.
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Curcic, S; Tiapko, O; Groschner, K Photopharmacology and opto-chemogenetics of TRPC channels-some therapeutic visions.
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Maki, RA; Holzer, M; Motamedchaboki, K; Malle, E; Masliah, E; Marsche, G; Reynolds, WF Human myeloperoxidase (hMPO) is expressed in neurons in the substantia nigra in Parkinson's disease and in the hMPO-α-synuclein-A53T mouse model, correlating with increased nitration and aggregation of α-synuclein and exacerbation of motor impairment.
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Fotoulaki, M; Giza, S; Jirsa, M; Grammatikopoulos, T; Miquel, R; Hytiroglou, P; Tsitouridis, I; Knisely, AS Beyond an Obvious Cause of Cholestasis in a Toddler: Compound Heterozygosity for ABCB11 Mutations.
PEDIATRICS. 2019; 143(5): Doi: 10.1542/peds.2018-2146 [OPEN ACCESS]
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Torner, M; Mangal, A; Scharnagl, H; Jansen, C; Praktiknjo, M; Queck, A; Gu, W; Schierwagen, R; Lehmann, J; Uschner, FE; Graf, C; Strassburg, CP; Fernandez, J; Stojakovic, T; Woitas, R; Trebicka, J Sex specificity of kidney markers to assess prognosis in cirrhotic patients with TIPS.
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Cadenas, C; Vosbeck, S; Edlund, K; Grgas, K; Madjar, K; Hellwig, B; Adawy, A; Glotzbach, A; Stewart, JD; Lesjak, MS; Franckenstein, D; Claus, M; Hayen, H; Schriewer, A; Gianmoena, K; Thaler, S; Schmidt, M; Micke, P; Pontén, F; Mardinoglu, A; Zhang, C; Käfferlein, HU; Watzl, C; Frank, S; Rahnenführer, J; Marchan, R; Hengstler, JG LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer.
Int J Cancer. 2019; 145(4): 901-915. Doi: 10.1002/ijc.32138 [OPEN ACCESS]
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Hofer, DC; Zirkovits, G; Pelzmann, HJ; Huber, K; Pessentheiner, AR; Xia, W; Uno, K; Miyazaki, T; Kon, K; Tsuneki, H; Pendl, T; Al Zoughbi, W; Madreiter-Sokolowski, CT; Trausinger, G; Abdellatif, M; Schoiswohl, G; Schreiber, R; Eisenberg, T; Magnes, C; Sedej, S; Eckhardt, M; Sasahara, M; Sasaoka, T; Nitta, A; Hoefler, G; Graier, WF; Kratky, D; Auwerx, J; Bogner-Strauss, JG N-acetylaspartate availability is essential for juvenile survival on fat-free diet and determines metabolic health.
FASEB J. 2019; 33(12):13808-13824 Doi: 10.1096/fj.201801323R [OPEN ACCESS]
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Butorac, C; Muik, M; Derler, I; Stadlbauer, M; Lunz, V; Krizova, A; Lindinger, S; Schober, R; Frischauf, I; Bhardwaj, R; Hediger, MA; Groschner, K; Romanin, C A novel STIM1-Orai1 gating interface essential for CRAC channel activation.
CELL CALCIUM. 2019; 79(6): 57-67. Doi: 10.1016/j.ceca.2019.02.009 [OPEN ACCESS]
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Svobodova, B; Lichtenegger, M; Platzer, D; Di Giuro, CML; de la Cruz, GG; Glasnov, T; Schreibmayer, W; Groschner, K A single point mutation in the TRPC3 lipid-recognition window generates supersensitivity to benzimidazole channel activators.
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Blom, WAM; Koppenol, WP; Hiemstra, H; Stojakovic, T; Scharnagl, H; Trautwein, EA A low-fat spread with added plant sterols and fish omega-3 fatty acids lowers serum triglyceride and LDL-cholesterol concentrations in individuals with modest hypercholesterolaemia and hypertriglyceridaemia.
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Klec, C; Ziomek, G; Pichler, M; Malli, R; Graier, WF Calcium Signaling in ß-cell Physiology and Pathology: A Revisit.
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Leopold, C; Duta-Mare, M; Sachdev, V; Goeritzer, M; Maresch, LK; Kolb, D; Reicher, H; Wagner, B; Stojakovic, T; Ruelicke, T; Haemmerle, G; Hoefler, G; Sattler, W; Kratky, D Hepatocyte-specific lysosomal acid lipase deficiency protects mice from diet-induced obesity but promotes hepatic inflammation.
Biochim Biophys Acta Mol Cell Biol Lipids. 2019; 1864(4):500-511 Doi: 10.1016/j.bbalip.2019.01.007 [OPEN ACCESS]
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Schilcher, I; Ledinski, G; Radulović, S; Hallström, S; Eichmann, T; Madl, T; Zhang, F; Leitinger, G; Kolb-Lenz, D; Darnhofer, B; Birner-Gruenberger, R; Wadsack, C; Kratky, D; Marsche, G; Frank, S; Cvirn, G Endothelial lipase increases antioxidative capacity of high-density lipoprotein.
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Trakaki, A; Sturm, GJ; Pregartner, G; Scharnagl, H; Eichmann, TO; Trieb, M; Knuplez, E; Holzer, M; Stadler, JT; Heinemann, A; Sturm, EM; Marsche, G Allergic rhinitis is associated with complex alterations in high-density lipoprotein composition and function.
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Grabner, GF; Fawzy, N; Pribasnig, MA; Trieb, M; Taschler, U; Holzer, M; Schweiger, M; Wolinski, H; Kolb, D; Horvath, A; Breinbauer, R; Rülicke, T; Rabl, R; Lass, A; Stadlbauer, V; Hutter-Paier, B; Stauber, RE; Fickert, P; Zechner, R; Marsche, G; Eichmann, TO; Zimmermann, R Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans.
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Ramms, B; Patel, S; Nora, C; Pessentheiner, AR; Chang, MW; Green, CR; Golden, GJ; Secrest, P; Krauss, RM; Metallo, CM; Benner, C; Alexander, VJ; Witztum, JL; Tsimikas, S; Esko, JD; Gordts, PLSM ApoC-III ASO promotes tissue LPL activity in the absence of apoE-mediated TRL clearance.
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Silbernagel, G; Steiner, LK; Hollstein, T; Fauler, G; Scharnagl, H; Stojakovic, T; Schumann, F; Bölükbasi, B; März, W; Steinhagen-Thiessen, E; Laufs, U; Kassner, U The interrelations between PCSK9 metabolism and cholesterol synthesis and absorption.
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Tardelli, M; Bruschi, FV; Claudel, T; Fuchs, CD; Auer, N; Kunczer, V; Stojakovic, T; Scharnagl, H; Habib, A; Grabner, GF; Zimmermann, R; Lotersztajn, S; Trauner, M Lack of monoacylglycerol lipase prevents hepatic steatosis by favoring lipid storage in adipose tissue and intestinal malabsorption.
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Bischof, H; Burgstaller, S; Waldeck-Weiermair, M; Rauter, T; Schinagl, M; Ramadani-Muja, J; Graier, WF; Malli, R Live-Cell Imaging of Physiologically Relevant Metal Ions Using Genetically Encoded FRET-Based Probes.
Cells. 2019; 8(5): Doi: 10.3390/cells8050492 [OPEN ACCESS]
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Rittchen, S; Heinemann, A Therapeutic Potential of Hematopoietic Prostaglandin D₂ Synthase in Allergic Inflammation.
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Denk, H; Abuja, PM; Zatloukal, K Animal models of NAFLD from the pathologist's point of view.
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Fanaee-Danesh, E; Gali, CC; Tadic, J; Zandl-Lang, M; Carmen Kober, A; Agujetas, VR; de Dios, C; Tam-Amersdorfer, C; Stracke, A; Albrecher, NM; Manavalan, APC; Reiter, M; Sun, Y; Colell, A; Madeo, F; Malle, E; Panzenboeck, U Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease by modulating amyloid-beta and cholesterol homeostasis in blood-brain barrier endothelial cells.
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Fickert, P; Wagner, M Preface - Animal models in liver disease.
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Pajed, L; Wagner, C; Taschler, U; Schreiber, R; Kolleritsch, S; Fawzy, N; Pototschnig, I; Schoiswohl, G; Pusch, LM; Wieser, BI; Vesely, P; Hoefler, G; Eichmann, TO; Zimmermann, R; Lass, A Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation.
J Biol Chem. 2019; 294(23):9118-9133 Doi: 10.1074/jbc.RA118.007201 [OPEN ACCESS]
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Fellendorf, FT; Platzer, M; Pilz, R; Rieger, A; Kapfhammer, HP; Mangge, H; Dalkner, N; Zelzer, S; Meinitzer, A; Birner, A; Bengesser, SA; Queissner, R; Hamm, C; Hartleb, R; Reininghaus, EZ Branched-chain amino acids are associated with metabolic parameters in bipolar disorder.
World J Biol Psychiatry. 2018; 1-6 Doi: 10.1080/15622975.2018.1487077
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Hollstein, T; Vogt, A; Grenkowitz, T; Stojakovic, T; März, W; Laufs, U; Bölükbasi, B; Steinhagen-Thiessen, E; Scharnagl, H; Kassner, U Treatment with PCSK9 inhibitors reduces atherogenic VLDL remnants in a real-world study.
Vascul Pharmacol. 2019; 116:8-15 Doi: 10.1016/j.vph.2019.03.002
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Huber, K; Hofer, DC; Trefely, S; Pelzmann, HJ; Madreiter-Sokolowski, C; Duta-Mare, M; Schlager, S; Trausinger, G; Stryeck, S; Graier, WF; Kolb, D; Magnes, C; Snyder, NW; Prokesch, A; Kratky, D; Madl, T; Wellen, KE; Bogner-Strauss, JG N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes.
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Grill, M; Högenauer, C; Blesl, A; Haybaeck, J; Golob-Schwarzl, N; Ferreirós, N; Thomas, D; Gurke, R; Trötzmüller, M; Köfeler, HC; Gallé, B; Schicho, R Members of the endocannabinoid system are distinctly regulated in inflammatory bowel disease and colorectal cancer.
Sci Rep. 2019; 9(1): 2358-2358. Doi: 10.1038/s41598-019-38865-4 [OPEN ACCESS]
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Banach, M; Bruckert, E; Descamps, OS; Ellegård, L; Ezhov, M; Föger, B; Fras, Z; Kovanen, PT; Latkovskis, G; März, W; Panagiotakos, DB; Paragh, G; Pella, D; Pirillo, A; Poli, A; Reiner, Ž; Silbernagel, G; Viigimaa, M; Vrablík, M; Catapano, AL The role of red yeast rice (RYR) supplementation in plasma cholesterol control: A review and expert opinion.
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Scharnagl, H; Stojakovic, T; Dieplinger, B; Dieplinger, H; Erhart, G; Kostner, GM; Herrmann, M; März, W; Grammer, TB Comparison of lipoprotein (a) serum concentrations measured by six commercially available immunoassays.
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Maliković, J; Vuyyuru, H; Koefeler, H; Smidak, R; Höger, H; Kalaba, P; Hussein, AM; Lubec, G; Korz, V Moderate differences in common feeding diets change lipid composition in the hippocampal dentate gyrus and affect spatial cognitive flexibility in male rats.
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Wadsack, D; Sattler, H; Kleber, ME; Eirich, K; Scharnagl, H; Fauler, G; März, W; Grammer, TB Recurrent tendosynovitis as a rare manifestation of a lipid disorder.
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Lütjohann, D; Björkhem, I; Friedrichs, S; Kerksiek, A; Lövgren-Sandblom, A; Geilenkeuser, WJ; Ahrends, R; Andrade, I; Ansorena, D; Astiasarán, I; Baila-Rueda, L; Barriuso, B; Becker, S; Bretillon, L; Browne, RW; Caccia, C; Ceglarek, U; Cenarro, A; Crick, PJ; Fauler, G; Garcia-Llatas, G; Gray, R; Griffiths, WJ; Gylling, H; Harding, S; Helmschrodt, C; Iuliano, L; Janssen, HG; Jones, P; Kaipiainen, L; Kannenberg, F; Lagarda, MJ; Leoni, V; Lottenberg, AM; MacKay, DS; Matysik, S; McDonald, J; Menendez-Carreño, M; Myrie, SB; Sutti Nunes, V; Ostlund, RE; Polisecki, E; Ramos, F; Rideout, TC; Schaefer, EJ; Schmitz, G; Wang, Y; Zerbinati, C; Diczfalusy, U; Schött, HF First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography-Urgent need for harmonisation of analytical methods.
J STEROID BIOCHEM. 2019; 190(10184): 115-125. Doi: 10.1016/j.jsbmb.2019.03.025 [OPEN ACCESS]
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Degoricija, V; Trbušić, M; Potočnjak, I; Radulović, B; Pregartner, G; Berghold, A; Scharnagl, H; Stojakovic, T; Tiran, B; Frank, S Serum concentrations of free fatty acids are associated with 3-month mortality in acute heart failure patients.
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Grill, M; Hasenoehrl, C; Kienzl, M; Kargl, J; Schicho, R Cellular localization and regulation of receptors and enzymes of the endocannabinoid system in intestinal and systemic inflammation.
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Höfer, CT; Di Lella, S; Dahmani, I; Jungnick, N; Bordag, N; Bobone, S; Huang, Q; Keller, S; Herrmann, A; Chiantia, S Structural determinants of the interaction between influenza A virus matrix protein M1 and lipid membranes.
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Gali, CC; Fanaee-Danesh, E; Zandl-Lang, M; Albrecher, NM; Tam-Amersdorfer, C; Stracke, A; Sachdev, V; Reichmann, F; Sun, Y; Avdili, A; Reiter, M; Kratky, D; Holzer, P; Lass, A; Kandimalla, KK; Panzenboeck, U Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-β in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice.
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Kiskova, T; Mytsko, Y; Schepelmann, M; Helmer, H; Fuchs, R; Miedl, H; Wadsack, C; Ellinger, I Expression of the neonatal Fc-receptor in placental-fetal endothelium and in cells of the placental immune system.
PLACENTA. 2019; 78(4): 36-43. Doi: 10.1016/j.placenta.2019.02.012
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Kaltenecker, D; Themanns, M; Mueller, KM; Spirk, K; Suske, T; Merkel, O; Kenner, L; Luís, A; Kozlov, A; Haybaeck, J; Müller, M; Han, X; Moriggl, R Hepatic growth hormone - JAK2 - STAT5 signalling: Metabolic function, non-alcoholic fatty liver disease and hepatocellular carcinoma progression.
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Waich, S; Roscher, A; Brunner-Krainz, M; Cortina, G; Köstl, G; Feichtinger, RG; Entenmann, A; Müller, T; Knisely, AS; Mayr, JA; Janecke, AR; Vodopiutz, J Severe Deoxyguanosine Kinase Deficiency in Austria: A 6-Patient Series.
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Safari, Z; Monnoye, M; Abuja, PM; Mariadassou, M; Kashofer, K; Gérard, P; Zatloukal, K Steatosis and gut microbiota dysbiosis induced by high-fat diet are reversed by 1-week chow diet administration.
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Durchschein, F; Eherer, A; Grill, M; Sturm, EM; Pommer, V; Langner, C; Högenauer, C; Schicho, R Involvement of EP2 and EP4 Receptors in Eosinophilic Esophagitis: A Pilot Study.
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Degoricija, V; Potočnjak, I; Gastrager, M; Pregartner, G; Berghold, A; Scharnagl, H; Stojakovic, T; Tiran, B; Marsche, G; Frank, S HDL subclasses and mortality in acute heart failure patients.
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Amor, M; Itariu, BK; Moreno-Viedma, V; Keindl, M; Jürets, A; Prager, G; Langer, F; Grablowitz, V; Zeyda, M; Stulnig, TM Serum Myostatin is Upregulated in Obesity and Correlates with Insulin Resistance in Humans.
EXP CLIN ENDOCR DIAB. 2019; 127(8): 550-556. Doi: 10.1055/a-0641-5546
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Schalli, M; Weber, P; Nasseri, SA; Gomez, AT; Muller, P; Stutz, AE; Withers, SG; Wolfsgruber, A; Wrodnigg, TM Biologically active branched-chain aminocyclopentane tetraols from d-galactose
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Zoidl, M; Wolfsgruber, A; Schalli, M; Nasseri, SA; Weber, P; Stütz, AE; Withers, SG; Wrodnigg, TM Synthesis of modified 1,5-imino-d-xylitols as ligands for lysosomal β-glucocerebrosidase.
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Li, JQ; Gong, JY; Knisely, AS; Zhang, MH; Wang, JS Recurrent acute liver failure associated with novel SCYL1 mutation: A case report
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Hamm, C; Queissner, R; Pilz, R; Birner, A; Platzer, M; Fellendorf, F; Maget, A; Bengesser, S; Dalkner, N; Reininghaus, B; Reininghaus, E [The relationship between intake of lithium and neuroradiological alterations in bipolar disorder. Are there predictors of clinical remission?]
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Klec, C; Madreiter-Sokolowski, CT; Stryeck, S; Sachdev, V; Duta-Mare, M; Gottschalk, B; Depaoli, MR; Rost, R; Hay, J; Waldeck-Weiermair, M; Kratky, D; Madl, T; Malli, R; Graier, WF Glycogen Synthase Kinase 3 Beta Controls Presenilin-1-Mediated Endoplasmic Reticulum Ca²⁺ Leak Directed to Mitochondria in Pancreatic Islets and β-Cells.
Cell Physiol Biochem. 2019; 52(1): 57-75. Doi: 10.33594/000000005 [OPEN ACCESS]
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Klec, C; Madreiter-Sokolowski, CT; Ziomek, G; Stryeck, S; Sachdev, V; Duta-Mare, M; Gottschalk, B; Depaoli, MR; Rost, R; Hay, J; Waldeck-Weiermair, M; Kratky, D; Madl, T; Malli, R; Graier, WF Presenilin-1 Established ER-Ca²⁺ Leak: a Follow Up on Its Importance for the Initial Insulin Secretion in Pancreatic Islets and β-Cells upon Elevated Glucose.
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Liebisch, G; Ahrends, R; Arita, M; Arita, M; Bowden, JA; Ejsing, CS; Griffiths, WJ; Holcapek, M; Kofeler, H; Mitchell, TW; Wenk, MR; Ekroos, K Lipidomics needs more standardization
NAT METAB. 2019; 1(8): 745-747. Doi: 10.1038/s42255-019-0094-z
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Maresch, LK; Benedikt, P; Feiler, U; Eder, S; Zierler, KA; Taschler, U; Kolleritsch, S; Eichmann, TO; Schoiswohl, G; Leopold, C; Wieser, BI; Lackner, C; Rülicke, T; van, Klinken, J; Kratky, D; Moustafa, T; Hoefler, G; Haemmerle, G Intestine-Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet-Induced Liver Steatosis and Obesity.
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Kleber, ME; Delgado, GE; Dawczynski, C; Lorkowski, S; März, W Associations of fats and carbohydrates with cardiovascular disease and mortality-PURE and simple?
LANCET. 2018; 391(10131): 1680-1681. Doi: 10.1016/S0140-6736(18)30798-0
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Mach, F; Ray, KK; Wiklund, O; Corsini, A; Catapano, AL; Bruckert, E; De Backer, G; Hegele, RA; Hovingh, GK; Jacobson, TA; Krauss, RM; Laufs, U; Leiter, LA; März, W; Nordestgaard, BG; Raal, FJ; Roden, M; Santos, RD; Stein, EA; Stroes, ES; Thompson, PD; Tokgözoglu, L; Vladutiu, GD; Gencer, B; Stock, JK; Ginsberg, HN; Chapman, MJ; European Atherosclerosis Society Consensus Panel Adverse effects of statin therapy: perception vs. the evidence - focus on glucose homeostasis, cognitive, renal and hepatic function, haemorrhagic stroke and cataract.
EUR HEART J. 2018; 39(27): 2526-2539. Doi: 10.1093/eurheartj/ehy182 [OPEN ACCESS]
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Ryu, JK; Rafalski, VA; Meyer-Franke, A; Adams, RA; Poda, SB; Rios Coronado, PE; Pedersen, LØ; Menon, V; Baeten, KM; Sikorski, SL; Bedard, C; Hanspers, K; Bardehle, S; Mendiola, AS; Davalos, D; Machado, MR; Chan, JP; Plastira, I; Petersen, MA; Pfaff, SJ; Ang, KK; Hallenbeck, KK; Syme, C; Hakozaki, H; Ellisman, MH; Swanson, RA; Zamvil, SS; Arkin, MR; Zorn, SH; Pico, AR; Mucke, L; Freedman, SB; Stavenhagen, JB; Nelson, RB; Akassoglou, K Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration.
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Genes (Basel). 2018; 9(3): Doi: 10.3390/genes9030165 [OPEN ACCESS]
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Koyani, CN; Trummer, C; Shrestha, N; Scheruebel, S; Bourgeois, B; Plastira, I; Kickmaier, S; Sourij, H; Rainer, PP; Madl, T; Sattler, W; Pelzmann, B; Malle, E; von Lewinski, D Saxagliptin but Not Sitagliptin Inhibits CaMKII and PKC via DPP9 Inhibition in Cardiomyocytes.
Front Physiol. 2018; 9:1622-1622 Doi: 10.3389/fphys.2018.01622 [OPEN ACCESS]
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Weber, P; Nasseri, SA; Pabst, BM; Torvisco, A; Müller, P; Paschke, E; Tschernutter, M; Windischhofer, W; Withers, SG; Wrodnigg, TM; Stütz, AE Potent GH20 N-Acetyl-β-d-hexosaminidase Inhibitors: N-Substituted 3-acetamido-4-amino-5-hydroxymethyl-cyclopentanediols.
Molecules. 2018; 23(3): 708 Doi: 10.3390/molecules23030708 [OPEN ACCESS]
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Zöhrer, E; Meinel, K; Fauler, G; Moser, VA; Greimel, T; Zobl, J; Schlagenhauf, A; Jahnel, J Neonatal sepsis leads to early rise of rare serum bile acid tauro-omega-muricholic acid (TOMCA).
Pediatr Res. 2018; 84(1):66-70 Doi: 10.1038/s41390-018-0007-y [OPEN ACCESS]
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Scherz, B; Rabl, R; Flunkert, S; Rohler, S; Neddens, J; Taub, N; Temmel, M; Panzenboeck, U; Niederkofler, V; Zimmermann, R; Hutter-Paier, B mTh1 driven expression of hTDP-43 results in typical ALS/FTLD neuropathological symptoms.
PLoS One. 2018; 13(5): e0197674-e0197674. Doi: 10.1371/journal.pone.0197674 [OPEN ACCESS]
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Schaider, M; Novak, T; Komposch, C; Leis, HJ; Raspotnig, G Methyl-ketones in the scent glands of Opiliones: a chemical trait of cyphophthalmi retrieved in the dyspnoan Nemastoma triste.
CHEMOECOLOGY. 2018; 28(2): 61-67. Doi: 10.1007/s00049-018-0257-5 [OPEN ACCESS]
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Contreras-Duarte, S; Chen, P; Andía, M; Uribe, S; Irarrázaval, P; Kopp, S; Kern, S; Marsche, G; Busso, D; Wadsack, C; Rigotti, A Attenuation of atherogenic apo B-48-dependent hyperlipidemia and high density lipoprotein remodeling induced by vitamin C and E combination and their beneficial effect on lethal ischemic heart disease in mice.
Biol Res. 2018; 51(1): 34-34. Doi: 10.1186/s40659-018-0183-6 [OPEN ACCESS]
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2017

Zechner, R; Madeo, F; Kratky, D Cytosolic lipolysis and lipophagy: two sides of the same coin.
Nat Rev Mol Cell Biol. 2017; 18(11):671-684 Doi: 10.1038/nrm.2017.76
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Hartler, J; Triebl, A; Ziegl, A; Trötzmüller, M; Rechberger, GN; Zeleznik, OA; Zierler, KA; Torta, F; Cazenave-Gassiot, A; Wenk, MR; Fauland, A; Wheelock, CE; Armando, AM; Quehenberger, O; Zhang, Q; Wakelam, MJO; Haemmerle, G; Spener, F; Köfeler, HC; Thallinger, GG Deciphering lipid structures based on platform-independent decision rules.
Nat Methods. 2017; 14(12): 1171-1174. Doi: 10.1038/nmeth.4470 [OPEN ACCESS]
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Zewinger, S; Kleber, ME; Rohrer, L; Lehmann, M; Triem, S; Jennings, RT; Petrakis, I; Dressel, A; Lepper, PM; Scharnagl, H; Ritsch, A; Thorand, B; Heier, M; Meisinger, C; de Las Heras Gala, T; Koenig, W; Wagenpfeil, S; Schwedhelm, E; Böger, RH; Laufs, U; von Eckardstein, A; Landmesser, U; Lüscher, TF; Fliser, D; März, W; Meinitzer, A; Speer, T Symmetric dimethylarginine, high-density lipoproteins and cardiovascular disease.
Eur Heart J. 2017; 38(20):1597-1607 Doi: 10.1093/eurheartj/ehx118 [OPEN ACCESS]
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Zewinger, S; Kleber, ME; Tragante, V; McCubrey, RO; Schmidt, AF; Direk, K; Laufs, U; Werner, C; Koenig, W; Rothenbacher, D; Mons, U; Breitling, LP; Brenner, H; Jennings, RT; Petrakis, I; Triem, S; Klug, M; Filips, A; Blankenberg, S; Waldeyer, C; Sinning, C; Schnabel, RB; Lackner, KJ; Vlachopoulou, E; Nygård, O; Svingen, GFT; Pedersen, ER; Tell, GS; Sinisalo, J; Nieminen, MS; Laaksonen, R; Trompet, S; Smit, RAJ; Sattar, N; Jukema, JW; Groesdonk, HV; Delgado, G; Stojakovic, T; Pilbrow, AP; Cameron, VA; Richards, AM; Doughty, RN; Gong, Y; Cooper-DeHoff, R; Johnson, J; Scholz, M; Beutner, F; Thiery, J; Smith, JG; Vilmundarson, RO; McPherson, R; Stewart, AFR; Cresci, S; Lenzini, PA; Spertus, JA; Olivieri, O; Girelli, D; Martinelli, NI; Leiherer, A; Saely, CH; Drexel, H; Mündlein, A; Braund, PS; Nelson, CP; Samani, NJ; Kofink, D; Hoefer, IE; Pasterkamp, G; Quyyumi, AA; Ko, YA; Hartiala, JA; Allayee, H; Tang, WHW; Hazen, SL; Eriksson, N; Held, C; Hagström, E; Wallentin, L; Åkerblom, A; Siegbahn, A; Karp, I; Labos, C; Pilote, L; Engert, JC; Brophy, JM; Thanassoulis, G; Bogaty, P; Szczeklik, W; Kaczor, M; Sanak, M; Virani, SS; Ballantyne, CM; Lee, VV; Boerwinkle, E; Holmes, MV; Horne, BD; Hingorani, A; Asselbergs, FW; Patel, RS; GENIUS-CHD consortium; Krämer, BK; Scharnagl, H; Fliser, D; März, W; Speer, T Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.
Lancet Diabetes Endocrinol. 2017; 5(7):534-543 Doi: 10.1016/S2213-8587(17)30096-7 [OPEN ACCESS]
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Bauer, L; Kern, S; Rogacev, KS; Emrich, IE; Zawada, A; Fliser, D; Heinemann, A; Heine, GH; Marsche, G HDL Cholesterol Efflux Capacity and Cardiovascular Events in Patients With Chronic Kidney Disease.
J Am Coll Cardiol. 2017; 69(2): 246-247. Doi: 10.1016/j.jacc.2016.10.054 [OPEN ACCESS]
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Fickert, P Bad memories from the gut may cause nightmares for the bile ducts.
J Hepatol. 2017; 66(1):5-7 Doi: 10.1016/j.jhep.2016.09.016 [OPEN ACCESS]
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Fickert, P; Hirschfield, GM; Denk, G; Marschall, HU; Altorjay, I; Färkkilä, M; Schramm, C; Spengler, U; Chapman, R; Bergquist, A; Schrumpf, E; Nevens, F; Trivedi, P; Reiter, FP; Tornai, I; Halilbasic, E; Greinwald, R; Pröls, M; Manns, MP; Trauner, M; European PSC norUDCA Study Group norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis.
J Hepatol. 2017; 67(3):549-558 Doi: 10.1016/j.jhep.2017.05.009 [OPEN ACCESS]
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Hanley, J; Dhar, DK; Mazzacuva, F; Fiadeiro, R; Burden, JJ; Lyne, AM; Smith, H; Straatman-Iwanowska, A; Banushi, B; Virasami, A; Mills, K; Lemaigre, FP; Knisely, AS; Howe, S; Sebire, N; Waddington, SN; Paulusma, CC; Clayton, P; Gissen, P Vps33b is crucial for structural and functional hepatocyte polarity.
J Hepatol. 2017; 66(5):1001-1011 Doi: 10.1016/j.jhep.2017.01.001 [OPEN ACCESS]
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Qiu, YL; Gong, JY; Feng, JY; Wang, RX; Han, J; Liu, T; Lu, Y; Li, LT; Zhang, MH; Sheps, JA; Wang, NL; Yan, YY; Li, JQ; Chen, L; Borchers, CH; Sipos, B; Knisely, AS; Ling, V; Xing, QH; Wang, JS Defects in myosin VB are associated with a spectrum of previously undiagnosed low γ-glutamyltransferase cholestasis.
Hepatology. 2017; 65(5):1655-1669 Doi: 10.1002/hep.29020 [OPEN ACCESS]
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Bischof, H; Rehberg, M; Stryeck, S; Artinger, K; Eroglu, E; Waldeck-Weiermair, M; Gottschalk, B; Rost, R; Deak, AT; Niedrist, T; Vujic, N; Lindermuth, H; Prassl, R; Pelzmann, B; Groschner, K; Kratky, D; Eller, K; Rosenkranz, AR; Madl, T; Plesnila, N; Graier, WF; Malli, R Novel genetically encoded fluorescent probes enable real-time detection of potassium in vitro and in vivo.
Nat Commun. 2017; 8(1):1422-1422 Doi: 10.1038/s41467-017-01615-z [OPEN ACCESS]
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Schweiger, M; Romauch, M; Schreiber, R; Grabner, GF; Hütter, S; Kotzbeck, P; Benedikt, P; Eichmann, TO; Yamada, S; Knittelfelder, O; Diwoky, C; Doler, C; Mayer, N; De, Cecco, W; Breinbauer, R; Zimmermann, R; Zechner, R Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice.
Nat Commun. 2017; 8:14859 Doi: 10.1038/ncomms14859 [OPEN ACCESS]
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Grabner, GF; Zimmermann, R; Schicho, R; Taschler, U Monoglyceride lipase as a drug target: At the crossroads of arachidonic acid metabolism and endocannabinoid signaling.
Pharmacol Ther. 2017; 175:35-46 Doi: 10.1016/j.pharmthera.2017.02.033 [OPEN ACCESS]
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Silbernagel, G; Pagel, P; Pfahlert, V; Genser, B; Scharnagl, H; Kleber, ME; Delgado, G; Ohrui, H; Ritsch, A; Grammer, TB; Koenig, W; März, W High-Density Lipoprotein Subclasses, Coronary Artery Disease, and Cardiovascular Mortality.
Clin Chem. 2017; 63(12):1886-1896 Doi: 10.1373/clinchem.2017.275636 [OPEN ACCESS]
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Holzer, M; Trieb, M; Marsche, G The complex high-density lipoprotein proteome: a matter of purification?
Kidney Int. 2017; 92(6): 1555-1555. Doi: 10.1016/j.kint.2017.08.024 [OPEN ACCESS]
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Mueller, KM; Hartmann, K; Kaltenecker, D; Vettorazzi, S; Bauer, M; Mauser, L; Amann, S; Jall, S; Fischer, K; Esterbauer, H; Müller, TD; Tschöp, MH; Magnes, C; Haybaeck, J; Scherer, T; Bordag, N; Tuckermann, JP; Moriggl, R Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition.
Diabetes. 2017; 66(2):272-286 Doi: 10.2337/db16-0381 [OPEN ACCESS]
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Wölkart, G; Schrammel, A; Koyani, CN; Scherübel, S; Zorn-Pauly, K; Malle, E; Pelzmann, B; Andrä, M; Ortner, A; Mayer, B Cardioprotective effects of 5-hydroxymethylfurfural mediated by inhibition of L-type Ca(2+) currents.
Br J Pharmacol. 2017; 174(20):3640-3653 Doi: 10.1111/bph.13967 [OPEN ACCESS]
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Grond, S; Eichmann, TO; Dubrac, S; Kolb, D; Schmuth, M; Fischer, J; Crumrine, D; Elias, PM; Haemmerle, G; Zechner, R; Lass, A; Radner, FPW PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides.
J Invest Dermatol. 2017; 137(2):394-402 Doi: 10.1016/j.jid.2016.08.036 [OPEN ACCESS]
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Grond, S; Radner, FPW; Eichmann, TO; Kolb, D; Grabner, GF; Wolinski, H; Gruber, R; Hofer, P; Heier, C; Schauer, S; Rülicke, T; Hoefler, G; Schmuth, M; Elias, PM; Lass, A; Zechner, R; Haemmerle, G Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation.
J Invest Dermatol. 2017; 137(2):403-413 Doi: 10.1016/j.jid.2016.09.025 [OPEN ACCESS]
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Wu, BJ; Li, Y; Ong, KL; Sun, Y; Shrestha, S; Hou, L; Johns, D; Barter, PJ; Rye, KA Reduction of In-Stent Restenosis by Cholesteryl Ester Transfer Protein Inhibition.
ARTERIOSCL THROM VAS. 2017; 37(12): 2333-2341. Doi: 10.1161/ATVBAHA.117.310051 [OPEN ACCESS]
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Winklhofer-Roob, BM; Faustmann, G; Roob, JM Low-density lipoprotein oxidation biomarkers in human health and disease and effects of bioactive compounds.
Free Radic Biol Med. 2017; 111(5):38-86 Doi: 10.1016/j.freeradbiomed.2017.04.345 [OPEN ACCESS]
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Zietzer, A; Buschmann, EE; Janke, D; Li, L; Brix, M; Meyborg, H; Stawowy, P; Jungk, C; Buschmann, I; Hillmeister, P Acute physical exercise and long-term individual shear rate therapy increase telomerase activity in human peripheral blood mononuclear cells.
Acta Physiol (Oxf). 2017; 220(2): 251-262. Doi: 10.1111/apha.12820
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Marsche, G; Zelzer, S; Meinitzer, A; Kern, S; Meissl, S; Pregartner, G; Weghuber, D; Almer, G; Mangge, H Adiponectin Predicts High-Density Lipoprotein Cholesterol Efflux Capacity in Adults Irrespective of Body Mass Index and Fat Distribution.
J Clin Endocrinol Metab. 2017; 102(11):4117-4123 Doi: 10.1210/jc.2017-00933 [OPEN ACCESS]
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Salminen, A; Vlachopoulou, E; Havulinna, AS; Tervahartiala, T; Sattler, W; Lokki, ML; Nieminen, MS; Perola, M; Salomaa, V; Sinisalo, J; Meri, S; Sorsa, T; Pussinen, PJ Genetic Variants Contributing to Circulating Matrix Metalloproteinase 8 Levels and Their Association With Cardiovascular Diseases: A Genome-Wide Analysis.
Circ Cardiovasc Genet. 2017; 10(6): Doi: 10.1161/CIRCGENETICS.117.001731 [OPEN ACCESS]
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Pessentheiner, AR; Huber, K; Pelzmann, HJ; Prokesch, A; Radner, FPW; Wolinski, H; Lindroos-Christensen, J; Hoefler, G; Rülicke, T; Birner-Gruenberger, R; Bilban, M; Bogner-Strauss, JG APMAP interacts with lysyl oxidase-like proteins, and disruption of Apmap leads to beneficial visceral adipose tissue expansion.
FASEB J. 2017; 31(9):4088-4103 Doi: 10.1096/fj.201601337R [OPEN ACCESS]
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Prokesch, A; Graef, FA; Madl, T; Kahlhofer, J; Heidenreich, S; Schumann, A; Moyschewitz, E; Pristoynik, P; Blaschitz, A; Knauer, M; Muenzner, M; Bogner-Strauss, JG; Dohr, G; Schulz, TJ; Schupp, M Liver p53 is stabilized upon starvation and required for amino acid catabolism and gluconeogenesis.
FASEB J. 2017; 31(2):732-742 Doi: 10.1096/fj.201600845R [OPEN ACCESS]
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Graff, M; Scott, RA; Justice, AE; Young, KL; Feitosa, MF; Barata, L; Winkler, TW; Chu, AY; Mahajan, A; Hadley, D; Xue, L; Workalemahu, T; Heard-Costa, NL; den Hoed, M; Ahluwalia, TS; Qi, Q; Ngwa, JS; Renström, F; Quaye, L; Eicher, JD; Hayes, JE; Cornelis, M; Kutalik, Z; Lim, E; Luan, J; Huffman, JE; Zhang, W; Zhao, W; Griffin, PJ; Haller, T; Ahmad, S; Marques-Vidal, PM; Bien, S; Yengo, L; Teumer, A; Smith, AV; Kumari, M; Harder, MN; Justesen, JM; Kleber, ME; Hollensted, M; Lohman, K; Rivera, NV; Whitfield, JB; Zhao, JH; Stringham, HM; Lyytikäinen, LP; Huppertz, C; Willemsen, G; Peyrot, WJ; Wu, Y; Kristiansson, K; Demirkan, A; Fornage, M; Hassinen, M; Bielak, LF; Cadby, G; Tanaka, T; Mägi, R; van der Most, PJ; Jackson, AU; Bragg-Gresham, JL; Vitart, V; Marten, J; Navarro, P; Bellis, C; Pasko, D; Johansson, Å; Snitker, S; Cheng, YC; Eriksson, J; Lim, U; Aadahl, M; Adair, LS; Amin, N; Balkau, B; Auvinen, J; Beilby, J; Bergman, RN; Bergmann, S; Bertoni, AG; Blangero, J; Bonnefond, A; Bonnycastle, LL; Borja, JB; Brage, S; Busonero, F; Buyske, S; Campbell, H; Chines, PS; Collins, FS; Corre, T; Smith, GD; Delgado, GE; Dueker, N; Dörr, M; Ebeling, T; Eiriksdottir, G; Esko, T; Faul, JD; Fu, M; Færch, K; Gieger, C; Gläser, S; Gong, J; Gordon-Larsen, P; Grallert, H; Grammer, TB; Grarup, N; van Grootheest, G; Harald, K; Hastie, ND; Havulinna, AS; Hernandez, D; Hindorff, L; Hocking, LJ; Holmens, OL; Holzapfel, C; Hottenga, JJ; Huang, J; Huang, T; Hui, J; Huth, C; Hutri-Kähönen, N; James, AL; Jansson, JO; Jhun, MA; Juonala, M; Kinnunen, L; Koistinen, HA; Kolcic, I; Komulainen, P; Kuusisto, J; Kvaløy, K; Kähönen, M; Lakka, TA; Launer, LJ; Lehne, B; Lindgren, CM; Lorentzon, M; Luben, R; Marre, M; Milaneschi, Y; Monda, KL; Montgomery, GW; De Moor, MHM; Mulas, A; Müller-Nurasyid, M; Musk, AW; Männikkö, R; Männistö, S; Narisu, N; Nauck, M; Nettleton, JA; Nolte, IM; Oldehinkel, AJ; Olden, M; Ong, KK; Padmanabhan, S; Paternoster, L; Perez, J; Perola, M; Peters, A; Peters, U; Peyser, PA; Prokopenko, I; Puolijoki, H; Raitakari, OT; Rankinen, T; Rasmussen-Torvik, LJ; Rawal, R; Ridker, PM; Rose, LM; Rudan, I; Sarti, C; Sarzynski, MA; Savonen, K; Scott, WR; Sanna, S; Shuldiner, AR; Sidney, S; Silbernagel, G; Smith, BH; Smith, JA; Snieder, H; Stančáková, A; Sternfeld, B; Swift, AJ; Tammelin, T; Tan, ST; Thorand, B; Thuillier, D; Vandenput, L; Vestergaard, H; van Vliet-Ostaptchouk, JV; Vohl, MC; Völker, U; Waeber, G; Walker, M; Wild, S; Wong, A; Wright, AF; Zillikens, MC; Zubair, N; Haiman, CA; Lemarchand, L; Gyllensten, U; Ohlsson, C; Hofman, A; Rivadeneira, F; Uitterlinden, AG; Pérusse, L; Wilson, JF; Hayward, C; Polasek, O; Cucca, F; Hveem, K; Hartman, CA; Tönjes, A; Bandinelli, S; Palmer, LJ; Kardia, SLR; Rauramaa, R; Sørensen, TIA; Tuomilehto, J; Salomaa, V; Penninx, BWJH; de Geus, EJC; Boomsma, DI; Lehtimäki, T; Mangino, M; Laakso, M; Bouchard, C; Martin, NG; Kuh, D; Liu, Y; Linneberg, A; März, W; Strauch, K; Kivimäki, M; Harris, TB; Gudnason, V; Völzke, H; Qi, L; Järvelin, MR; Chambers, JC; Kooner, JS; Froguel, P; Kooperberg, C; Vollenweider, P; Hallmans, G; Hansen, T; Pedersen, O; Metspalu, A; Wareham, NJ; Langenberg, C; Weir, DR; Porteous, DJ; Boerwinkle, E; Chasman, DI; CHARGE Consortium; EPIC-InterAct Consortium; PAGE Consortium; Abecasis, GR; Barroso, I; McCarthy, MI; Frayling, TM; O'Connell, JR; van Duijn, CM; Boehnke, M; Heid, IM; Mohlke, KL; Strachan, DP; Fox, CS; Liu, CT; Hirschhorn, JN; Klein, RJ; Johnson, AD; Borecki, IB; Franks, PW; North, KE; C Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
PLoS Genet. 2017; 13(4): e1006528-e1006528. Doi: 10.1371/journal.pgen.1006528 [OPEN ACCESS]
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Plastira, I; Bernhart, E; Goeritzer, M; DeVaney, T; Reicher, H; Hammer, A; Lohberger, B; Wintersperger, A; Zucol, B; Graier, WF; Kratky, D; Malle, E; Sattler, W Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype.
J Neuroinflammation. 2017; 14(1):253-253 Doi: 10.1186/s12974-017-1024-1 [OPEN ACCESS]
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Schlager, S; Vujic, N; Korbelius, M; Duta-Mare, M; Dorow, J; Leopold, C; Rainer, S; Wegscheider, M; Reicher, H; Ceglarek, U; Sattler, W; Radovic, B; Kratky, D Lysosomal lipid hydrolysis provides substrates for lipid mediator synthesis in murine macrophages.
Oncotarget. 2017; 8(25):40037-40051 Doi: 10.18632/oncotarget.16673 [OPEN ACCESS]
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Vujic, N; Korbelius, M; Leopold, C; Duta-Mare, M; Rainer, S; Schlager, S; Goeritzer, M; Kolb, D; Eichmann, TO; Diwoky, C; Zimmer, A; Zimmermann, R; Lass, A; Radovic, B; Kratky, D Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice.
Oncotarget. 2017; 8(20):33122-33136 Doi: 10.18632/oncotarget.16529 [OPEN ACCESS]
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Hirschmugl, B; Desoye, G; Catalano, P; Klymiuk, I; Scharnagl, H; Payr, S; Kitzinger, E; Schliefsteiner, C; Lang, U; Wadsack, C; Hauguel-de Mouzon, S Maternal obesity modulates intracellular lipid turnover in the human term placenta.
Int J Obes (Lond). 2017; 41(2):317-323 Doi: 10.1038/ijo.2016.188 [OPEN ACCESS]
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Hofer, DC; Pessentheiner, AR; Pelzmann, HJ; Schlager, S; Madreiter-Sokolowski, CT; Kolb, D; Eichmann, TO; Rechberger, G; Bilban, M; Graier, WF; Kratky, D; Bogner-Strauss, JG Critical role of the peroxisomal protein PEX16 in white adipocyte development and lipid homeostasis.
Biochim Biophys Acta Mol Cell Biol Lipids. 2017; 1862(3):358-368 Doi: 10.1016/j.bbalip.2016.12.009 [OPEN ACCESS]
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Kober, AC; Manavalan, APC; Tam-Amersdorfer, C; Holmér, A; Saeed, A; Fanaee-Danesh, E; Zandl, M; Albrecher, NM; Björkhem, I; Kostner, GM; Dahlbäck, B; Panzenboeck, U Implications of cerebrovascular ATP-binding cassette transporter G1 (ABCG1) and apolipoprotein M in cholesterol transport at the blood-brain barrier.
Biochim Biophys Acta Mol Cell Biol Lipids. 2017; 1862(6):573-588 Doi: 10.1016/j.bbalip.2017.03.003
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Triebl, A; Hartler, J; Trötzmüller, M; C Köfeler, H Lipidomics: Prospects from a technological perspective.
Biochim Biophys Acta Mol Cell Biol Lipids. 2017; 1862(8):740-746 Doi: 10.1016/j.bbalip.2017.03.004 [OPEN ACCESS]
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Silbernagel, G; Scharnagl, H; Kleber, ME; Stojakovic, T; März, W Circulating proprotein convertase subtilisin-kexin type 9, all-cause mortality, and cardiovascular mortality: The Ludwigshafen Risk and Cardiovascular Health study.
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2016

Hou, L; Heilbronner, U; Degenhardt, F; Adli, M; Akiyama, K; Akula, N; Ardau, R; Arias, B; Backlund, L; Banzato, CE; Benabarre, A; Bengesser, S; Bhattacharjee, AK; Biernacka, JM; Birner, A; Brichant-Petitjean, C; Bui, ET; Cervantes, P; Chen, GB; Chen, HC; Chillotti, C; Cichon, S; Clark, SR; Colom, F; Cousins, DA; Cruceanu, C; Czerski, PM; Dantas, CR; Dayer, A; Étain, B; Falkai, P; Forstner, AJ; Frisén, L; Fullerton, JM; Gard, S; Garnham, JS; Goes, FS; Grof, P; Gruber, O; Hashimoto, R; Hauser, J; Herms, S; Hoffmann, P; Hofmann, A; Jamain, S; Jiménez, E; Kahn, JP; Kassem, L; Kittel-Schneider, S; Kliwicki, S; König, B; Kusumi, I; Lackner, N; Laje, G; Landén, M; Lavebratt, C; Leboyer, M; Leckband, SG; Jaramillo, CA; MacQueen, G; Manchia, M; Martinsson, L; Mattheisen, M; McCarthy, MJ; McElroy, SL; Mitjans, M; Mondimore, FM; Monteleone, P; Nievergelt, CM; Nöthen, MM; Ösby, U; Ozaki, N; Perlis, RH; Pfennig, A; Reich-Erkelenz, D; Rouleau, GA; Schofield, PR; Schubert, KO; Schweizer, BW; Seemüller, F; Severino, G; Shekhtman, T; Shilling, PD; Shimoda, K; Simhandl, C; Slaney, CM; Smoller, JW; Squassina, A; Stamm, T; Stopkova, P; Tighe, SK; Tortorella, A; Turecki, G; Volkert, J; Witt, S; Wright, A; Young, LT; Zandi, PP; Potash, JB; DePaulo, JR; Bauer, M; Reininghaus, EZ; Novák, T; Aubry, JM; Maj, M; Baune, BT; Mitchell, PB; Vieta, E; Frye, MA; Rybakowski, JK; Kuo, PH; Kato, T; Grigoroiu-Serbanescu, M; Reif, A; Del Zompo, M; Bellivier, F; Schalling, M; Wray, NR; Kelsoe, JR; Alda, M; Rietschel, M; McMahon, FJ; Schulze, TG Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study.
Lancet. 2016; 387(10023):1085-1093 Doi: 10.1016/S0140-6736(16)00143-4 [OPEN ACCESS]
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Laaksonen, R; Ekroos, K; Sysi-Aho, M; Hilvo, M; Vihervaara, T; Kauhanen, D; Suoniemi, M; Hurme, R; März, W; Scharnagl, H; Stojakovic, T; Vlachopoulou, E; Lokki, ML; Nieminen, MS; Klingenberg, R; Matter, CM; Hornemann, T; Jüni, P; Rodondi, N; Räber, L; Windecker, S; Gencer, B; Pedersen, ER; Tell, GS; Nygård, O; Mach, F; Sinisalo, J; Lüscher, TF Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol.
Eur Heart J. 2016; 37(25):1967-1976 Doi: 10.1093/eurheartj/ehw148 [OPEN ACCESS]
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März, W; Ritsch, A Cholesterol Efflux Capacity: Choke Point of Reverse Cholesterol Traffic?
J Am Coll Cardiol. 2016; 67(21):2488-2491 Doi: 10.1016/j.jacc.2016.04.005 [OPEN ACCESS]
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Krones, E; Wagner, M Fibroblast growth factor 19 meets mammalian target of rapamycin: A mitogenic Tête-à-Tête under consideration.
Hepatology. 2016; 64(4):1028-1030 Doi: 10.1002/hep.28691
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Wagner, M; Choi, S; Panzitt, K; Mamrosh, JL; Lee, JM; Zaufel, A; Xiao, R; Wooton-Kee, R; Ståhlman, M; Newgard, CB; Borén, J; Moore, DD Liver receptor homolog-1 is a critical determinant of methyl-pool metabolism.
Hepatology. 2016; 63(1):95-106 Doi: 10.1002/hep.28124 [OPEN ACCESS]
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Wagner, M; Fickert, P; Zollner, G Secretin and cholestasis, two sides of a coin.
Hepatology. 2016; 64(3):714-716 Doi: 10.1002/hep.28687 [OPEN ACCESS]
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Jandl, K; Stacher, E; Bálint, Z; Sturm, EM; Maric, J; Peinhaupt, M; Luschnig, P; Aringer, I; Fauland, A; Konya, V; Dahlen, SE; Wheelock, CE; Kratky, D; Olschewski, A; Marsche, G; Schuligoi, R; Heinemann, A Activated prostaglandin D2 receptors on macrophages enhance neutrophil recruitment into the lung.
J Allergy Clin Immunol. 2016; 137(3):833-843 Doi: 10.1016/j.jaci.2015.11.012 [OPEN ACCESS]
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Bartuzi, P; Billadeau, DD; Favier, R; Rong, S; Dekker, D; Fedoseienko, A; Fieten, H; Wijers, M; Levels, JH; Huijkman, N; Kloosterhuis, N; van der Molen, H; Brufau, G; Groen, AK; Elliott, AM; Kuivenhoven, JA; Plecko, B; Grangl, G; McGaughran, J; Horton, JD; Burstein, E; Hofker, MH; van de Sluis, B CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL.
Nat Commun. 2016; 7(5):10961-10961 Doi: 10.1038/ncomms10961 [OPEN ACCESS]
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Eroglu, E; Gottschalk, B; Charoensin, S; Blass, S; Bischof, H; Rost, R; Madreiter-Sokolowski, CT; Pelzmann, B; Bernhart, E; Sattler, W; Hallström, S; Malinski, T; Waldeck-Weiermair, M; Graier, WF; Malli, R Development of novel FP-based probes for live-cell imaging of nitric oxide dynamics.
Nat Commun. 2016; 7(3):10623-10623 Doi: 10.1038/ncomms10623 [OPEN ACCESS]
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Roier, S; Zingl, FG; Cakar, F; Durakovic, S; Kohl, P; Eichmann, TO; Klug, L; Gadermaier, B; Weinzerl, K; Prassl, R; Lass, A; Daum, G; Reidl, J; Feldman, MF; Schild, S A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria.
Nat Commun. 2016; 7:10515 Doi: 10.1038/ncomms10515 [OPEN ACCESS]
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Walford, GA; Gustafsson, S; Rybin, D; Stančáková, A; Chen, H; Liu, CT; Hong, J; Jensen, RA; Rice, K; Morris, AP; Mägi, R; Tönjes, A; Prokopenko, I; Kleber, ME; Delgado, G; Silbernagel, G; Jackson, AU; Appel, EV; Grarup, N; Lewis, JP; Montasser, ME; Landenvall, C; Staiger, H; Luan, J; Frayling, TM; Weedon, MN; Xie, W; Morcillo, S; Martínez-Larrad, MT; Biggs, ML; Chen, YD; Corbaton-Anchuelo, A; Færch, K; Gómez-Zumaquero, JM; Goodarzi, MO; Kizer, JR; Koistinen, HA; Leong, A; Lind, L; Lindgren, C; Machicao, F; Manning, AK; Martín-Núñez, GM; Rojo-Martínez, G; Rotter, JI; Siscovick, DS; Zmuda, JM; Zhang, Z; Serrano-Rios, M; Smith, U; Soriguer, F; Hansen, T; Jørgensen, TJ; Linnenberg, A; Pedersen, O; Walker, M; Langenberg, C; Scott, RA; Wareham, NJ; Fritsche, A; Häring, HU; Stefan, N; Groop, L; O'Connell, JR; Boehnke, M; Bergman, RN; Collins, FS; Mohlke, KL; Tuomilehto, J; März, W; Kovacs, P; Stumvoll, M; Psaty, BM; Kuusisto, J; Laakso, M; Meigs, JB; Dupuis, J; Ingelsson, E; Florez, JC Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci.
Diabetes. 2016; 65(10):3200-3211 Doi: 10.2337/db16-0199 [OPEN ACCESS]
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Klionsky, DJ; Abdelmohsen, K; Abe, A; Abedin, MJ; Abeliovich, H; Acevedo Arozena, A; Adachi, H; Adams, CM; Adams, PD; Adeli, K; Adhihetty, PJ; Adler, SG; Agam, G; Agarwal, R; ... Malli, R; ... Sedej, S; ... et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Autophagy. 2016; 12(1): 1-222. Doi: 10.1080/15548627.2015.1100356 [OPEN ACCESS]
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Krane, V; Schmidt, KR; Gutjahr-Lengsfeld, LJ; Mann, JF; März, W; Swoboda, F; Wanner, C; 4D Study Investigators (the German Diabetes and Dialysis Study Investigators) Long-term effects following 4 years of randomized treatment with atorvastatin in patients with type 2 diabetes mellitus on hemodialysis.
Kidney Int. 2016; 89(6):1380-1387 Doi: 10.1016/j.kint.2015.12.033 [OPEN ACCESS]
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Huang, J; Li, L; Lian, J; Schauer, S; Vesely, PW; Kratky, D; Hoefler, G; Lehner, R Tumor-Induced Hyperlipidemia Contributes to Tumor Growth.
Cell Rep. 2016; 15(2): 336-348. Doi: 10.1016/j.celrep.2016.03.020 [OPEN ACCESS]
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Frei, RB; Luschnig, P; Parzmair, GP; Peinhaupt, M; Schranz, S; Fauland, A; Wheelock, CE; Heinemann, A; Sturm, EM Cannabinoid receptor 2 augments eosinophil responsiveness and aggravates allergen-induced pulmonary inflammation in mice.
Allergy. 2016; 71(7):944-956 Doi: 10.1111/all.12858 [OPEN ACCESS]
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Derler, I; Jardin, I; Stathopulos, PB; Muik, M; Fahrner, M; Zayats, V; Pandey, SK; Poteser, M; Lackner, B; Absolonova, M; Schindl, R; Groschner, K; Ettrich, R; Ikura, M; Romanin, C Cholesterol modulates Orai1 channel function.
Sci Signal. 2016; 9(412):ra10-ra10 Doi: 10.1126/scisignal.aad7808 [OPEN ACCESS]
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Giroud, M; Pisani, DF; Karbiener, M; Barquissau, V; Ghandour, RA; Tews, D; Fischer-Posovszky, P; Chambard, JC; Knippschild, U; Niemi, T; Taittonen, M; Nuutila, P; Wabitsch, M; Herzig, S; Virtanen, KA; Langin, D; Scheideler, M; Amri, EZ miR-125b affects mitochondrial biogenesis and impairs brite adipocyte formation and function.
Mol Metab. 2016; 5(8):615-625 Doi: 10.1016/j.molmet.2016.06.005 [OPEN ACCESS]
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Tardelli, M; Zeyda, K; Moreno-Viedma, V; Wanko, B; Grün, NG; Staffler, G; Zeyda, M; Stulnig, TM Osteopontin is a key player for local adipose tissue macrophage proliferation in obesity.
Mol Metab. 2016; 5(11):1131-1137 Doi: 10.1016/j.molmet.2016.09.003 [OPEN ACCESS]
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Roeseler, E; Julius, U; Heigl, F; Spitthoever, R; Heutling, D; Breitenberger, P; Leebmann, J; Lehmacher, W; Kamstrup, PR; Nordestgaard, BG; Maerz, W; Noureen, A; Schmidt, K; Kronenberg, F; Heibges, A; Klingel, R; Pro(a)LiFe-Study Group Lipoprotein Apheresis for Lipoprotein(a)-Associated Cardiovascular Disease: Prospective 5 Years of Follow-Up and Apolipoprotein(a) Characterization.
Arterioscler Thromb Vasc Biol. 2016; 36(9):2019-2027 Doi: 10.1161/ATVBAHA.116.307983 [OPEN ACCESS]
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Radović, B; Vujić, N; Leopold, C; Schlager, S; Goeritzer, M; Patankar, JV; Korbelius, M; Kolb, D; Reindl, J; Wegscheider, M; Tomin, T; Birner-Gruenberger, R; Schittmayer, M; Groschner, L; Magnes, C; Diwoky, C; Frank, S; Steyrer, E; Du, H; Graier, WF; Madl, T; Kratky, D Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice.
Diabetologia. 2016; 59(8):1743-1752 Doi: 10.1007/s00125-016-3968-6 [OPEN ACCESS]
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Radnai, B; Sturm, EM; Stančić, A; Jandl, K; Labocha, S; Ferreirós, N; Grill, M; Hasenoehrl, C; Gorkiewicz, G; Marsche, G; Heinemann, Á; Högenauer, C; Schicho, R Eosinophils Contribute to Intestinal Inflammation via Chemoattractant Receptor-homologous Molecule Expressed on Th2 Cells, CRTH2, in Experimental Crohn's Disease.
J Crohns Colitis. 2016; 10(9):1087-1095 Doi: 10.1093/ecco-jcc/jjw061 [OPEN ACCESS]
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Degendorfer, G; Chuang, CY; Kawasaki, H; Hammer, A; Malle, E; Yamakura, F; Davies, MJ Peroxynitrite-mediated oxidation of plasma fibronectin.
Free Radic Biol Med. 2016; 97(3):602-615 Doi: 10.1016/j.freeradbiomed.2016.06.013
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Nusshold, C; Üllen, A; Kogelnik, N; Bernhart, E; Reicher, H; Plastira, I; Glasnov, T; Zangger, K; Rechberger, G; Kollroser, M; Fauler, G; Wolinski, H; Weksler, BB; Romero, IA; Kohlwein, SD; Couraud, PO; Malle, E; Sattler, W Assessment of electrophile damage in a human brain endothelial cell line utilizing a clickable alkyne analog of 2-chlorohexadecanal.
Free Radic Biol Med. 2016; 90: 59-74. Doi: 10.1016/j.freeradbiomed.2015.11.010 [OPEN ACCESS]
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Aschauer, P; Rengachari, S; Lichtenegger, J; Schittmayer, M; Das, KM; Mayer, N; Breinbauer, R; Birner-Gruenberger, R; Gruber, CC; Zimmermann, R; Gruber, K; Oberer, M Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p.
Biochim Biophys Acta. 2016; 1861(5):462-470 Doi: 10.1016/j.bbalip.2016.02.005 [OPEN ACCESS]
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Sachdev, V; Leopold, C; Bauer, R; Patankar, JV; Iqbal, J; Obrowsky, S; Boverhof, R; Doktorova, M; Scheicher, B; Goeritzer, M; Kolb, D; Turnbull, AV; Zimmer, A; Hoefler, G; Hussain, MM; Groen, AK; Kratky, D Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism.
Biochim Biophys Acta. 2016; 1861(9 Pt A):1132-1141 Doi: 10.1016/j.bbalip.2016.06.014 [OPEN ACCESS]
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Trieb, M; Horvath, A; Birner-Gruenberger, R; Spindelboeck, W; Stadlbauer, V; Taschler, U; Curcic, S; Stauber, RE; Holzer, M; Pasterk, L; Heinemann, A; Marsche, G Liver disease alters high-density lipoprotein composition, metabolism and function.
Biochim Biophys Acta. 2016; 1861(7):630-638 Doi: 10.1016/j.bbalip.2016.04.013 [OPEN ACCESS]
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Vogl, F; Humpolickova, J; Amaro, M; Koller, D; Kofeler, H; Zenzmaier, E; Hof, M; Hermetter, A Role of protein kinase C delta in apoptotic signaling of oxidized phospholipids in RAW 264.7 macrophages
BBA-MOL CELL BIOL L. 2016; 1861(4): 320-330. Doi: 10.1016/j.bbalip.2015.12.009
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Kargl, J; Andersen, L; Hasenöhrl, C; Feuersinger, D; Stančić, A; Fauland, A; Magnes, C; El-Heliebi, A; Lax, S; Uranitsch, S; Haybaeck, J; Heinemann, A; Schicho, R GPR55 promotes migration and adhesion of colon cancer cells indicating a role in metastasis.
Br J Pharmacol. 2016; 173(1):142-154 Doi: 10.1111/bph.13345 [OPEN ACCESS]
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Al-Zoughbi, W; Pichler, M; Gorkiewicz, G; Guertl-Lackner, B; Haybaeck, J; Jahn, SW; Lackner, C; Liegl-Atzwanger, B; Popper, H; Schauer, S; Nusshold, E; Kindt, AS; Trajanoski, Z; Speicher, MR; Haemmerle, G; Zimmermann, R; Zechner, R; Vesely, PW; Hoefler, G Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia.
Oncotarget. 2016; 7(23):33832-33840 Doi: 10.18632/oncotarget.9418 [OPEN ACCESS]
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Bettermann, K; Mehta, AK; Hofer, EM; Wohlrab, C; Golob-Schwarzl, N; Svendova, V; Schimek, MG; Stumptner, C; Thüringer, A; Speicher, MR; Lackner, C; Zatloukal, K; Denk, H; Haybaeck, J Keratin 18-deficiency results in steatohepatitis and liver tumors in old mice: A model of steatohepatitis-associated liver carcinogenesis.
Oncotarget. 2016; 7(45):73309-73322 Doi: 10.18632/oncotarget.12325 [OPEN ACCESS]
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Meshcheryakova, A; Svoboda, M; Tahir, A; Köfeler, HC; Triebl, A; Mungenast, F; Heinze, G; Gerner, C; Zimmermann, P; Jaritz, M; Mechtcheriakova, D Exploring the role of sphingolipid machinery during the epithelial to mesenchymal transition program using an integrative approach.
Oncotarget. 2016; 7(16):22295-22323 Doi: 10.18632/oncotarget.7947 [OPEN ACCESS]
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Plastira, I; Bernhart, E; Goeritzer, M; Reicher, H; Kumble, VB; Kogelnik, N; Wintersperger, A; Hammer, A; Schlager, S; Jandl, K; Heinemann, A; Kratky, D; Malle, E; Sattler, W 1-Oleyl-lysophosphatidic acid (LPA) promotes polarization of BV-2 and primary murine microglia towards an M1-like phenotype.
J Neuroinflammation. 2016; 13(1): 205-205. Doi: 10.1186/s12974-016-0701-9 [OPEN ACCESS]
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Grün, NG; Zeyda, K; Moreno-Viedma, V; Strohmeier, K; Staffler, G; Zeyda, M; Stulnig, TM A humanized osteopontin mouse model and its application in immunometabolic obesity studies.
Transl Res. 2016; 178(10):63-73 Doi: 10.1016/j.trsl.2016.07.009
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Koyani, CN; Kitz, K; Rossmann, C; Bernhart, E; Huber, E; Trummer, C; Windischhofer, W; Sattler, W; Malle, E Activation of the MAPK/Akt/Nrf2-Egr1/HO-1-GCLc axis protects MG-63 osteosarcoma cells against 15d-PGJ2-mediated cell death.
Biochem Pharmacol. 2016; 104:29-41 Doi: 10.1016/j.bcp.2016.01.011 [OPEN ACCESS]
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Kollerits, B; Drechsler, C; Krane, V; Lamina, C; März, W; Dieplinger, H; Ritz, E; Wanner, C; Kronenberg, F; German Diabetes and Dialysis Study Investigators Lipoprotein(a) concentrations, apolipoprotein(a) isoforms and clinical endpoints in haemodialysis patients with type 2 diabetes mellitus: results from the 4D Study.
Nephrol Dial Transplant. 2016; 31(11):1901-1908 Doi: 10.1093/ndt/gfv428 [OPEN ACCESS]
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Leis, HJ; Windischhofer, W Calcium-independent phospholipases A2 in murine osteoblastic cells and their inhibition by bromoenol lactone: impact on arachidonate dynamics and prostaglandin synthesis.
J Enzyme Inhib Med Chem. 2016; 31(6):1203-1213 Doi: 10.3109/14756366.2015.1114929 [OPEN ACCESS]
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Giroud, M; Karbiener, M; Pisani, DF; Ghandour, RA; Beranger, GE; Niemi, T; Taittonen, M; Nuutila, P; Virtanen, KA; Langin, D; Scheideler, M; Amri, EZ Let-7i-5p represses brite adipocyte function in mice and humans.
Sci Rep. 2016; 6(11):28613-28613 Doi: 10.1038/srep28613 [OPEN ACCESS]
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Holzer, M; Kern, S; Birner-Grünberger, R; Curcic, S; Heinemann, A; Marsche, G Refined purification strategy for reliable proteomic profiling of HDL_2/3: Impact on proteomic complexity.
Sci Rep. 2016; 6(368):38533-38533 Doi: 10.1038/srep38533 [OPEN ACCESS]
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Pasterk, L; Lemesch, S; Leber, B; Trieb, M; Curcic, S; Stadlbauer, V; Schuligoi, R; Schicho, R; Heinemann, A; Marsche, G Oxidized plasma albumin promotes platelet-endothelial crosstalk and endothelial tissue factor expression.
Sci Rep. 2016; 6(3):22104-22104 Doi: 10.1038/srep22104 [OPEN ACCESS]
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Poteser, M; Leitinger, G; Pritz, E; Platzer, D; Frischauf, I; Romanin, C; Groschner, K Live-cell imaging of ER-PM contact architecture by a novel TIRFM approach reveals extension of junctions in response to store-operated Ca²⁺-entry.
Sci Rep. 2016; 6(S 01):35656-35656 Doi: 10.1038/srep35656 [OPEN ACCESS]
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Prokesch, A; Pelzmann, HJ; Pessentheiner, AR; Huber, K; Madreiter-Sokolowski, CT; Drougard, A; Schittmayer, M; Kolb, D; Magnes, C; Trausinger, G; Graier, WF; Birner-Gruenberger, R; Pospisilik, JA; Bogner-Strauss, JG N-acetylaspartate catabolism determines cytosolic acetyl-CoA levels and histone acetylation in brown adipocytes.
Sci Rep. 2016; 6(3):23723-23723 Doi: 10.1038/srep23723 [OPEN ACCESS]
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Themanns, M; Mueller, KM; Kessler, SM; Golob-Schwarzl, N; Mohr, T; Kaltenecker, D; Bourgeais, J; Paier-Pourani, J; Friedbichler, K; Schneller, D; Schlederer, M; Zebedin-Brandl, E; Terracciano, LM; Han, X; Kenner, L; Wagner, KU; Mikulits, W; Kozlov, AV; Heim, MH; Gouilleux, F; Haybaeck, J; Moriggl, R Hepatic Deletion of Janus Kinase 2 Counteracts Oxidative Stress in Mice.
Sci Rep. 2016; 6(4):34719-34719 Doi: 10.1038/srep34719 [OPEN ACCESS]
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Grenkowitz, T; Kassner, U; Wühle-Demuth, M; Salewsky, B; Rosada, A; Zemojtel, T; Hopfenmüller, W; Isermann, B; Borucki, K; Heigl, F; Laufs, U; Wagner, S; Kleber, ME; Binner, P; März, W; Steinhagen-Thiessen, E; Demuth, I Clinical characterization and mutation spectrum of German patients with familial hypercholesterolemia.
Atherosclerosis. 2016; 253(19-20):88-93 Doi: 10.1016/j.atherosclerosis.2016.08.037
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Kleber, ME; Delgado, GE; Lorkowski, S; März, W; von Schacky, C Omega-3 fatty acids and mortality in patients referred for coronary angiography. The Ludwigshafen Risk and Cardiovascular Health Study.
Atherosclerosis. 2016; 252(3):175-181 Doi: 10.1016/j.atherosclerosis.2016.06.049 [OPEN ACCESS]
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Vujic, N; Schlager, S; Eichmann, TO; Madreiter-Sokolowski, CT; Goeritzer, M; Rainer, S; Schauer, S; Rosenberger, A; Woelfler, A; Doddapattar, P; Zimmermann, R; Hoefler, G; Lass, A; Graier, WF; Radovic, B; Kratky, D Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice.
Atherosclerosis. 2016; 244:9-21 Doi: 10.1016/j.atherosclerosis.2015.10.109 [OPEN ACCESS]
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Vinod, M; Patankar, JV; Sachdev, V; Frank, S; Graier, WF; Kratky, D; Kostner, GM MiR-206 is expressed in pancreatic islets and regulates glucokinase activity.
Am J Physiol Endocrinol Metab. 2016; 311(1):E175-E185 Doi: 10.1152/ajpendo.00510.2015 [OPEN ACCESS]
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Kessler, SM; Laggai, S; Van Wonterg, E; Gemperlein, K; Müller, R; Haybaeck, J; Vandenbroucke, RE; Ogris, M; Libert, C; Kiemer, AK Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation.
Front Physiol. 2016; 7(9):147-147 Doi: 10.3389/fphys.2016.00147 [OPEN ACCESS]
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Grumet, L; Eichmann, TO; Taschler, U; Zierler, KA; Leopold, C; Moustafa, T; Radovic, B; Romauch, M; Yan, C; Du, H; Haemmerle, G; Zechner, R; Fickert, P; Kratky, D; Zimmermann, R; Lass, A Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover.
J Biol Chem. 2016; 291(34):17977-87 Doi: 10.1074/jbc.M116.724054 [OPEN ACCESS]
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Kawala, MA; Bohndorf, M; Graffmann, N; Wruck, W; Zatloukal, K; Adjaye, J Characterization of dermal fibroblast-derived iPSCs from a patient with high grade steatosis.
Stem Cell Res. 2016; 17(3):568-571 Doi: 10.1016/j.scr.2016.10.007 [OPEN ACCESS]
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Kawala, MA; Bohndorf, M; Graffmann, N; Wruck, W; Zatloukal, K; Adjaye, J Characterization of dermal fibroblast-derived iPSCs from a patient with low grade steatosis.
Stem Cell Res. 2016; 17(3):547-549 Doi: 10.1016/j.scr.2016.10.004 [OPEN ACCESS]
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Kawala, MA; Bohndorf, M; Graffmann, N; Wruck, W; Zatloukal, K; Adjaye, J Characterization of iPSCs derived from dermal fibroblasts from a healthy 19year old female.
Stem Cell Res. 2016; 17(3):597-599 Doi: 10.1016/j.scr.2016.10.002 [OPEN ACCESS]
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Tomazic, PV; Birner-Gruenberger, R; Leitner, A; Spoerk, S; Lang-Loidolt, D Seasonal proteome changes of nasal mucus reflect perennial inflammatory response and reduced defence mechanisms and plasticity in allergic rhinitis.
J Proteomics. 2016; 133(4):153-160 Doi: 10.1016/j.jprot.2015.12.021 [OPEN ACCESS]
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Schuch, K; Wanko, B; Ambroz, K; Castelo-Rosa, A; Moreno-Viedma, V; Grün, NG; Leitner, L; Staffler, G; Zeyda, M; Stulnig, TM Osteopontin affects macrophage polarization promoting endocytic but not inflammatory properties.
Obesity (Silver Spring). 2016; 24(7):1489-1498 Doi: 10.1002/oby.21510 [OPEN ACCESS]
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Theiler, A; Konya, V; Pasterk, L; Maric, J; Bärnthaler, T; Lanz, I; Platzer, W; Schuligoi, R; Heinemann, A The EP1/EP3 receptor agonist 17-pt-PGE₂ acts as an EP4 receptor agonist on endothelial barrier function and in a model of LPS-induced pulmonary inflammation.
Vascul Pharmacol. 2016; 87(4):180-189 Doi: 10.1016/j.vph.2016.09.008 [OPEN ACCESS]
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Svobodova, B; Groschner, K Mechanisms of lipid regulation and lipid gating in TRPC channels.
Cell Calcium. 2016; 59(6):271-279 Doi: 10.1016/j.ceca.2016.03.012 [OPEN ACCESS]
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Hasenoehrl, C; Taschler, U; Storr, M; Schicho, R The gastrointestinal tract - a central organ of cannabinoid signaling in health and disease.
Neurogastroenterol Motil. 2016; 28(12):1765-1780 Doi: 10.1111/nmo.12931 [OPEN ACCESS]
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Gouni-Berthold, I; Descamps, OS; Fraass, U; Hartfield, E; Allcott, K; Dent, R; März, W Systematic review of published Phase 3 data on anti-PCSK9 monoclonal antibodies in patients with hypercholesterolaemia.
Br J Clin Pharmacol. 2016; 82(6):1412-1443 Doi: 10.1111/bcp.13066 [OPEN ACCESS]
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Hartmann, P; Seebauer, CT; Mazagova, M; Horvath, A; Wang, L; Llorente, C; Varki, NM; Brandl, K; Ho, SB; Schnabl, B Deficiency of intestinal mucin-2 protects mice from diet-induced fatty liver disease and obesity.
Am J Physiol Gastrointest Liver Physiol. 2016; 310(5):G310-G322 Doi: 10.1152/ajpgi.00094.2015 [OPEN ACCESS]
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Reiter, FP; Wimmer, R; Wottke, L; Artmann, R; Nagel, JM; Carranza, MO; Mayr, D; Rust, C; Fickert, P; Trauner, M; Gerbes, AL; Hohenester, S; Denk, GU Role of interleukin-1 and its antagonism of hepatic stellate cell proliferation and liver fibrosis in the Abcb4(-/-) mouse model.
World J Hepatol. 2016; 8(8):401-410 Doi: 10.4254/wjh.v8.i8.401 [OPEN ACCESS]
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Tang, Y; Fickert, P; Trauner, M; Marcus, N; Blomenkamp, K; Teckman, J Autophagy induced by exogenous bile acids is therapeutic in a model of α-1-AT deficiency liver disease.
Am J Physiol Gastrointest Liver Physiol. 2016; 311(1):G156-G165 Doi: 10.1152/ajpgi.00143.2015 [OPEN ACCESS]
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Rezania, S; Kammerer, S; Li, C; Steinecker-Frohnwieser, B; Gorischek, A; DeVaney, TT; Verheyen, S; Passegger, CA; Tabrizi-Wizsy, NG; Hackl, H; Platzer, D; Zarnani, AH; Malle, E; Jahn, SW; Bauernhofer, T; Schreibmayer, W Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner.
BMC Cancer. 2016; 16(1):628-628 Doi: 10.1186/s12885-016-2664-8 [OPEN ACCESS]
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Leis, HJ; Windischhofer, W Potentiation of endothelin-1-induced prostaglandin E2 formation by Ni(2+) and Sr(2+) in murine osteoblastic MC3T3-E1 cells.
J Trace Elem Med Biol. 2016; 33(3):81-86 Doi: 10.1016/j.jtemb.2015.10.001
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Besenboeck, C; Cvitic, S; Lang, U; Desoye, G; Wadsack, C Going into labor and beyond: phospholipase A2 in pregnancy.
Reproduction. 2016; 151(6):R91-R102 Doi: 10.1530/REP-15-0519 [OPEN ACCESS]
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Konya, V; Mjösberg, J Lipid mediators as regulators of human ILC2 function in allergic diseases.
Immunol Lett. 2016; 179:36-42 Doi: 10.1016/j.imlet.2016.07.006 [OPEN ACCESS]
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Birner-Gruenberger, R; Breinbauer, R Tracking Protein S-Fatty Acylation with Proteomics.
Chembiochem. 2016; 17(16):1488-1490 Doi: 10.1002/cbic.201600314
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Fengler, VH; Macheiner, T; Kessler, SM; Czepukojc, B; Gemperlein, K; Müller, R; Kiemer, AK; Magnes, C; Haybaeck, J; Lackner, C; Sargsyan, K Susceptibility of Different Mouse Wild Type Strains to Develop Diet-Induced NAFLD/AFLD-Associated Liver Disease.
PLoS One. 2016; 11(5):e0155163-e0155163 Doi: 10.1371/journal.pone.0155163 [OPEN ACCESS]
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Lipovšek, S; Novak, T; Janžekovič, F; Weiland, N; Leitinger, G Malpighian Tubule Cells in Overwintering Cave Crickets Troglophilus cavicola (Kollar, 1833) and T. neglectus Krauss, 1879 (Rhaphidophoridae, Ensifera).
PLoS One. 2016; 11(7):e0158598-e0158598 Doi: 10.1371/journal.pone.0158598 [OPEN ACCESS]
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Pertl, L; Kern, S; Weger, M; Hausberger, S; Trieb, M; Gasser-Steiner, V; Haas, A; Scharnagl, H; Heinemann, A; Marsche, G High-Density Lipoprotein Function in Exudative Age-Related Macular Degeneration.
PLoS One. 2016; 11(5):e0154397-e0154397 Doi: 10.1371/journal.pone.0154397 [OPEN ACCESS]
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Potočnjak, I; Degoricija, V; Trbušić, M; Terešak, SD; Radulović, B; Pregartner, G; Berghold, A; Tiran, B; Marsche, G; Frank, S Metrics of High-Density Lipoprotein Function and Hospital Mortality in Acute Heart Failure Patients.
PLoS One. 2016; 11(6):e0157507-e0157507 Doi: 10.1371/journal.pone.0157507 [OPEN ACCESS]
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Rogacev, KS; Heine, GH; Silbernagel, G; Kleber, ME; Seiler, S; Emrich, I; Lennartz, S; Werner, C; Zawada, AM; Fliser, D; Böhm, M; März, W; Scharnagl, H; Laufs, U PCSK9 Plasma Concentrations Are Independent of GFR and Do Not Predict Cardiovascular Events in Patients with Decreased GFR.
PLoS One. 2016; 11(1):e0146920-e0146920 Doi: 10.1371/journal.pone.0146920 [OPEN ACCESS]
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Vujic, N; Porter Abate, J; Schlager, S; David, T; Kratky, D; Koliwad, SK Acyl-CoA:Diacylglycerol Acyltransferase 1 Expression Level in the Hematopoietic Compartment Impacts Inflammation in the Vascular Plaques of Atherosclerotic Mice.
PLoS One. 2016; 11(5):e0156364-e0156364 Doi: 10.1371/journal.pone.0156364 [OPEN ACCESS]
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Klapper, M; Findeis, D; Koefeler, H; Döring, F Methyl group donors abrogate adaptive responses to dietary restriction in C. elegans.
Genes Nutr. 2016; 11(6):4-4 Doi: 10.1186/s12263-016-0522-4 [OPEN ACCESS]
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Tiapko, O; Bacsa, B; de la Cruz, GG; Glasnov, T; Groschner, K Optopharmacological control of TRPC channels by coumarin-caged lipids is associated with a phototoxic membrane effect.
Sci China Life Sci. 2016; 59(8):802-810 Doi: 10.1007/s11427-016-5095-5 [OPEN ACCESS]
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März, W; Scharnagl, H; Gouni-Berthold, I; Silbernagel, G; Dressel, A; Grammer, TB; Landmesser, U; Dieplinger, H; Windler, E; Laufs, U LDL-Cholesterol: Standards of Treatment 2016: A German Perspective.
Am J Cardiovasc Drugs. 2016; 16(5):323-336 Doi: 10.1007/s40256-016-0179-y [OPEN ACCESS]
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Albrecht, C; Caniggia, I; Clifton, V; Göhner, C; Harris, L; Hemmings, D; Jawerbaum, A; Johnstone, E; Jones, H; Keelan, J; Lewis, R; Mitchell, M; Murthi, P; Powell, T; Saffery, R; Smith, R; Vaillancourt, C; Wadsack, C; Salomon, C IFPA meeting 2015 workshop report III: nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid.
Placenta. 2016; 48 Suppl 1(2):S12-S16 Doi: 10.1016/j.placenta.2016.01.003
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Kessler, SM; Haybaeck, J; Kiemer, AK Insulin-Like Growth Factor 2 - The Oncogene and its Accomplices.
Curr Pharm Des. 2016; 22(39):5948-5961 Doi: 10.2174/1381612822666160713100235
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Triebl, A; Weissengruber, S; Trötzmüller, M; Lankmayr, E; Köfeler, H Quantitative analysis of N-acylphosphatidylethanolamine molecular species in rat brain using solid-phase extraction combined with reversed-phase chromatography and tandem mass spectrometry.
J Sep Sci. 2016; 39(13):2474-2480 Doi: 10.1002/jssc.201600172 [OPEN ACCESS]
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Thonhofer, M; Weber, P; Santana, AG; Fischer, R; Pabst, BM; Paschke, E; Schalli, M; Stütz, AE; Tschernutter, M; Windischhofer, W; Withers, SG Synthesis of C-5a-chain extended derivatives of 4-epi-isofagomine: Powerful β-galactosidase inhibitors and low concentration activators of GM1-gangliosidosis-related human lysosomal β-galactosidase.
Bioorg Med Chem Lett. 2016; 26(5):1438-1442 Doi: 10.1016/j.bmcl.2016.01.059
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Gaggl, M; Lajic, N; Heinze, G; Voigtländer, T; Sunder-Plassmann, R; Paschke, E; Fauler, G; Sunder-Plassmann, G; Mundigler, G Screening for Fabry Disease by Urinary Globotriaosylceramide Isoforms Measurement in Patients with Left Ventricular Hypertrophy.
Int J Med Sci. 2016; 13(5):340-346 Doi: 10.7150/ijms.14997 [OPEN ACCESS]
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Bodner, M; Vagalinski, B; Makarov, SE; Antić, DŽ; Vujisić, LV; Leis, HJ; Raspotnig, G "Quinone Millipedes" Reconsidered: Evidence for a Mosaic-Like Taxonomic Distribution of Phenol-Based Secretions across the Julidae.
J Chem Ecol. 2016; 42(3):249-258 Doi: 10.1007/s10886-016-0680-4 [OPEN ACCESS]
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Alfakry, H; Malle, E; Koyani, CN; Pussinen, PJ; Sorsa, T Neutrophil proteolytic activation cascades: a possible mechanistic link between chronic periodontitis and coronary heart disease.
Innate Immun. 2016; 22(1):85-99 Doi: 10.1177/1753425915617521 [OPEN ACCESS]
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Enko, D; Meinitzer, A; Mangge, H; Kriegshäuser, G; Halwachs-Baumann, G; Reininghaus, EZ; Bengesser, SA; Schnedl, WJ Concomitant Prevalence of Low Serum Diamine Oxidase Activity and Carbohydrate Malabsorption.
Can J Gastroenterol Hepatol. 2016; 2016(2):4893501-4893501 Doi: 10.1155/2016/4893501 [OPEN ACCESS]
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Thonhofer, M; Gonzalez Santana, A; Fischer, R; Torvisco Gomez, A; Saf, R; Schalli, M; Stütz, AE; Withers, SG 5-Fluoro derivatives of 4-epi-isofagomine as D-galactosidase inhibitors and potential pharmacological chaperones for GM1-gangliosidosis as well as Fabry's disease.
Carbohydr Res. 2016; 420(5): 6-12. Doi: 10.1016/j.carres.2015.10.009
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Thonhofer, M; Weber, P; Gonzalez Santana, A; Tysoe, C; Fischer, R; Pabst, BM; Paschke, E; Schalli, M; Stütz, AE; Tschernutter, M; Windischhofer, W; Withers, SG Synthesis of C-5a-substituted derivatives of 4-epi-isofagomine: notable β-galactosidase inhibitors and activity promotors of GM1-gangliosidosis related human lysosomal β-galactosidase mutant R201C.
Carbohydr Res. 2016; 429(15):71-80 Doi: 10.1016/j.carres.2016.03.020
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Stumptner, C; Gogg-Kamerer, M; Viertler, C; Denk, H; Zatloukal, K Immunofluorescence and Immunohistochemical Detection of Keratins.
Methods Enzymol. 2016; 568:139-162 Doi: 10.1016/bs.mie.2015.08.003
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Rossberg, W; Saternus, R; Wagenpfeil, S; Kleber, M; März, W; Reichrath, S; Vogt, T; Reichrath, J Human Pigmentation, Cutaneous Vitamin D Synthesis and Evolution: Variants of Genes (SNPs) Involved in Skin Pigmentation Are Associated with 25(OH)D Serum Concentration.
Anticancer Res. 2016; 36(3):1429-1437
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Leis, HJ; Windischhofer, W Ionomycin induces prostaglandin E2 formation in murine osteoblastic MC3T3-E1 cells via mechanisms independent of its ionophoric nature.
Biochem Cell Biol. 2016; 94(3):236-240 Doi: 10.1139/bcb-2015-0148 [OPEN ACCESS]
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Zöhrer, E; Resch, B; Scharnagl, H; Schlagenhauf, A; Fauler, G; Stojakovic, T; Hofer, N; Lang, U; Jahnel, J Serum bile acids in term and preterm neonates: A case-control study determining reference values and the influence of early-onset sepsis.
Medicine (Baltimore). 2016; 95(44):e5219-e5219 Doi: 10.1097/MD.0000000000005219 [OPEN ACCESS]
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Grammer, T; Kleber, M; Silbernagel, G; Scharnagl, H; März, W [Residual risk: The roles of triglycerides and high density lipoproteins].
Dtsch Med Wochenschr. 2016; 141(12):870-877 Doi: 10.1055/s-0042-104049
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Herrera, E; Desoye, G Maternal and fetal lipid metabolism under normal and gestational diabetic conditions.
Horm Mol Biol Clin Investig. 2016; 26(2):109-127 Doi: 10.1515/hmbci-2015-0025 [OPEN ACCESS]
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Mangge, H Beyond Cholesterol - New Cardiovascular Biomarkers.
Nestle Nutr Inst Workshop Ser. 2016; 84: 81-88. Doi: 10.1159/000436990
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Sarosiek, I; Schicho, R; Blandon, P; Bashashati, M Urinary metabolites as noninvasive biomarkers of gastrointestinal diseases: A clinical review.
World J Gastrointest Oncol. 2016; 8(5):459-465 Doi: 10.4251/wjgo.v8.i5.459 [OPEN ACCESS]
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Wagner, M; Trauner, M Recent advances in understanding and managing cholestasis.
F1000Res. 2016; 5(8): Doi: 10.12688/f1000research.8012.1 [OPEN ACCESS]
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2015

Silbernagel, G; Baumgartner, I; März, W Ezetimibe plus a Statin after Acute Coronary Syndromes.
N Engl J Med. 2015; 373(15):1473-1473 Doi: 10.1056/NEJMc1509363#SA1 [OPEN ACCESS]
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Silbernagel, G; Baumgartner, I; März, W Mutations in NPC1L1 and coronary heart disease.
N Engl J Med. 2015; 372(9):882-882 Doi: 10.1056/NEJMc1500124#SA3 [OPEN ACCESS]
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Do, R; Stitziel, NO; Won, HH; Jørgensen, AB; Duga, S; Angelica Merlini, P; Kiezun, A; Farrall, M; Goel, A; Zuk, O; Guella, I; Asselta, R; Lange, LA; Peloso, GM; Auer, PL; NHLBI Exome Sequencing Project; Girelli, D; Martinelli, N; Farlow, DN; DePristo, MA; Roberts, R; Stewart, AF; Saleheen, D; Danesh, J; Epstein, SE; Sivapalaratnam, S; Hovingh, GK; Kastelein, JJ; Samani, NJ; Schunkert, H; Erdmann, J; Shah, SH; Kraus, WE; Davies, R; Nikpay, M; Johansen, CT; Wang, J; Hegele, RA; Hechter, E; Marz, W; Kleber, ME; Huang, J; Johnson, AD; Li, M; Burke, GL; Gross, M; Liu, Y; Assimes, TL; Heiss, G; Lange, EM; Folsom, AR; Taylor, HA; Olivieri, O; Hamsten, A; Clarke, R; Reilly, DF; Yin, W; Rivas, MA; Donnelly, P; Rossouw, JE; Psaty, BM; Herrington, DM; Wilson, JG; Rich, SS; Bamshad, MJ; Tracy, RP; Cupples, LA; Rader, DJ; Reilly, MP; Spertus, JA; Cresci, S; Hartiala, J; Tang, WH; Hazen, SL; Allayee, H; Reiner, AP; Carlson, CS; Kooperberg, C; Jackson, RD; Boerwinkle, E; Lander, ES; Schwartz, SM; Siscovick, DS; McPherson, R; Tybjaerg-Hansen, A; Abecasis, GR; Watkins, H; Nickerson, DA; Ardissino, D; Sunyaev, SR; O'Donnell, CJ; Altshuler, D; Gabriel, S; Kathiresan, S Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction.
NATURE. 2015; 518(7537): 102-106. Doi: 10.1038/nature13917 [OPEN ACCESS]
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Locke, AE; Kahali, B; Berndt, SI; Justice, AE; Pers, TH; Day, FR; Powell, C; Vedantam, S; Buchkovich, ML; Yang, J; Croteau-Chonka, DC; Esko, T; Fall, T; Ferreira, T; Gustafsson, S; Kutalik, Z; Luan, J; Mägi, R; Randall, JC; Winkler, TW; Wood, AR; Workalemahu, T; Faul, JD; Smith, JA; Zhao, JH; Zhao, W; Chen, J; Fehrmann, R; Hedman, ÅK; Karjalainen, J; Schmidt, EM; Absher, D; Amin, N; Anderson, D; Beekman, M; Bolton, JL; Bragg-Gresham, JL; Buyske, S; Demirkan, A; Deng, G; Ehret, GB; Feenstra, B; Feitosa, MF; Fischer, K; Goel, A; Gong, J; Jackson, AU; Kanoni, S; Kleber, ME; Kristiansson, K; Lim, U; Lotay, V; Mangino, M; Leach, IM; Medina-Gomez, C; Medland, SE; Nalls, MA; Palmer, CD; Pasko, D; Pechlivanis, S; Peters, MJ; Prokopenko, I; Shungin, D; Stančáková, A; Strawbridge, RJ; Sung, YJ; Tanaka, T; Teumer, A; Trompet, S; van der Laan, SW; van Setten, J; Van Vliet-Ostaptchouk, JV; Wang, Z; Yengo, L; Zhang, W; Isaacs, A; Albrecht, E; Ärnlöv, J; Arscott, GM; Attwood, AP; Bandinelli, S; Barrett, A; Bas, IN; Bellis, C; Bennett, AJ; Berne, C; Blagieva, R; Blüher, M; Böhringer, S; Bonnycastle, LL; Böttcher, Y; Boyd, HA; Bruinenberg, M; Caspersen, IH; Chen, YI; Clarke, R; Daw, EW; de Craen, AJM; Delgado, G; Dimitriou, M; Doney, ASF; Eklund, N; Estrada, K; Eury, E; Folkersen, L; Fraser, RM; Garcia, ME; Geller, F; Giedraitis, V; Gigante, B; Go, AS; Golay, A; Goodall, AH; Gordon, SD; Gorski, M; Grabe, HJ; Grallert, H; Grammer, TB; Gräßler, J; Grönberg, H; Groves, CJ; Gusto, G; Haessler, J; Hall, P; Haller, T; Hallmans, G; Hartman, CA; Hassinen, M; Hayward, C; Heard-Costa, NL; Helmer, Q; Hengstenberg, C; Holmen, O; Hottenga, JJ; James, AL; Jeff, JM; Johansson, Å; Jolley, J; Juliusdottir, T; Kinnunen, L; Koenig, W; Koskenvuo, M; Kratzer, W; Laitinen, J; Lamina, C; Leander, K; Lee, NR; Lichtner, P; Lind, L; Lindström, J; Lo, KS; Lobbens, S; Lorbeer, R; Lu, Y; Mach, F; Magnusson, PKE; Mahajan, A; McArdle, WL; McLachlan, S; Menni, C; Merger, S; Mihailov, E; Milani, L; Moayyeri, A; Monda, KL; Morken, MA; Mulas, A; Müller, G; Müller-Nurasyid, M; Musk, AW; Nagaraja, R; Nöthen, MM; Nolte, IM; Pilz, S; Rayner, NW; Renstrom, F; Rettig, R; Ried, JS; Ripke, S; Robertson, NR; Rose, LM; Sanna, S; Scharnagl, H; Scholtens, S; Schumacher, FR; Scott, WR; Seufferlein, T; Shi, J; Smith, AV; Smolonska, J; Stanton, AV; Steinthorsdottir, V; Stirrups, K; Stringham, HM; Sundström, J; Swertz, MA; Swift, AJ; Syvänen, AC; Tan, ST; Tayo, BO; Thorand, B; Thorleifsson, G; Tyrer, JP; Uh, HW; Vandenput, L; Verhulst, FC; Vermeulen, SH; Verweij, N; Vonk, JM; Waite, LL; Warren, HR; Waterworth, D; Weedon, MN; Wilkens, LR; Willenborg, C; Wilsgaard, T; Wojczynski, MK; Wong, A; Wright, AF; Zhang, Q; LifeLines Cohort Study; Brennan, EP; Choi, M; Dastani, Z; Drong, AW; Eriksson, P; Franco-Cereceda, A; Gådin, JR; Gharavi, AG; Goddard, ME; Handsaker, RE; Huang, J; Karpe, F; Kathiresan, S; Keildson, S; Kiryluk, K; Kubo, M; Lee, JY; Liang, L; Lifton, RP; Ma, B; McCarroll, SA; McKnight, AJ; Min, JL; Moffatt, MF; Montgomery, GW; Murabito, JM; Nicholson, G; Nyholt, DR; Okada, Y; Perry, JRB; Dorajoo, R; Reinmaa, E; Salem, RM; Sandholm, N; Scott, RA; Stolk, L; Takahashi, A; Tanaka, T; van 't Hooft, FM; Vinkhuyzen, AAE; Westra, HJ; Zheng, W; Zondervan, KT; ADIPOGen Consortium; AGEN-BMI Working Group; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GLGC; ICBP; MAGIC Investigators; MuTHER Consortium; MIGen Consortium; PAGE Consortium; ReproGen Consortium; GENIE Consortium; International Endogene Consort ... Genetic studies of body mass index yield new insights for obesity biology.
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Laufs, U; Scharnagl, H; Halle, M; Windler, E; Endres, M; März, W Treatment Options for Statin-Associated Muscle Symptoms.
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Stančić, A; Jandl, K; Hasenöhrl, C; Reichmann, F; Marsche, G; Schuligoi, R; Heinemann, A; Storr, M; Schicho, R The GPR55 antagonist CID16020046 protects against intestinal inflammation.
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Das, SK; Stadelmeyer, E; Schauer, S; Schwarz, A; Strohmaier, H; Claudel, T; Zechner, R; Hoefler, G; Vesely, PW Micro RNA-124a regulates lipolysis via adipose triglyceride lipase and comparative gene identification 58.
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Sala, P; Pötz, S; Brunner, M; Trötzmüller, M; Fauland, A; Triebl, A; Hartler, J; Lankmayr, E; Köfeler, HC Determination of oxidized phosphatidylcholines by hydrophilic interaction liquid chromatography coupled to Fourier transform mass spectrometry.
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Neve, EP; Köfeler, H; Hendriks, DF; Nordling, Å; Gogvadze, V; Mkrtchian, S; Näslund, E; Ingelman-Sundberg, M Expression and Function of mARC: Roles in Lipogenesis and Metabolic Activation of Ximelagatran.
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Schneider, A; Schneider, MP; Krieter, DH; Genser, B; Scharnagl, H; Stojakovic, T; Wanner, C; Drechsler, C Effect of High-Flux Dialysis on Circulating FGF-23 Levels in End-Stage Renal Disease Patients: Results from a Randomized Trial.
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Dražić, T; Sachdev, V; Leopold, C; Patankar, JV; Malnar, M; Hećimović, S; Levak-Frank, S; Habuš, I; Kratky, D Synthesis and evaluation of novel amide amino-β-lactam derivatives as cholesterol absorption inhibitors.
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Wultsch, A; Kaufmann, U; Ott, J; Stojakovic, T; Scharnagl, H; Stangl, H; Strobl, WM Profound Changes in Sex Hormone Levels during Cross-Sex Hormone Therapy of Transsexuals do not Alter Serum Cholesterol Acceptor Capacity.
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Falkensammer, J; Frech, A; Duschek, N; Gasteiger, S; Stojakovic, T; Scharnagl, H; Huber, K; Fraedrich, G; Greiner, A Prognostic relevance of ischemia-modified albumin and NT-proBNP in patients with peripheral arterial occlusive disease.
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Adage, T; Konya, V; Weber, C; Strutzmann, E; Fuchs, T; Zankl, C; Gerlza, T; Jeremic, D; Heinemann, A; Kungl, AJ Targeting glycosaminoglycans in the lung by an engineered CXCL8 as a novel therapeutic approach to lung inflammation.
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Meier, SM; Wultsch, A; Hollaus, M; Ammann, M; Pemberger, E; Liebscher, F; Lambers, B; Fruhwürth, S; Stojakovic, T; Scharnagl, H; Schmidt, A; Springer, A; Becker, J; Aufricht, C; Handisurya, A; Kapeller, S; Röhrl, C; Stangl, H; Strobl, W Effect of chronic kidney disease on macrophage cholesterol efflux.
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Jahnel, J; Zöhrer, E; Alisi, A; Ferrari, F; Ceccarelli, S; De Vito, R; Scharnagl, H; Stojakovic, T; Fauler, G; Trauner, M; Nobili, V Serum Bile Acid Levels in Children With Nonalcoholic Fatty Liver Disease.
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Gerlza, T; Winkler, S; Atlic, A; Zankl, C; Konya, V; Kitic, N; Strutzmann, E; Knebl, K; Adage, T; Heinemann, A; Weis, R; Kungl, AJ Designing a mutant CCL2-HSA chimera with high glycosaminoglycan-binding affinity and selectivity.
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Tomazic, PV; Birner-Gruenberger, R; Leitner, A; Darnhofer, B; Spoerk, S; Lang-Loidolt, D Apolipoproteins have a potential role in nasal mucus of allergic rhinitis patients: a proteomic study.
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Kleber, ME; Siekmeier, R; Delgado, G; Grammer, TB; Winkelmann, BR; Scharnagl, H; Boehm, BO; März, W C-reactive protein and lipoprotein-associated phospholipase A2 in smokers and nonsmokers of the Ludwigshafen Risk and Cardiovascular Health study.
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Schwerdtfeger, AR; Scharnagl, H; Stojakovic, T; Rathner, EM Cognitive Avoidant Coping Is Associated with Higher Carotid Intima Media Thickness Among Middle-Aged Adults.
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Brückner, A; Stabentheiner, E; Leis, HJ; Raspotnig, G Chemical basis of unwettability in Liacaridae (Acari, Oribatida): specific variations of a cuticular acid/ester-based system.
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Lipovšek, S; Novak, T; Janžekovič, F; Leitinger, G Changes in the midgut diverticula in the harvestmen Amilenus aurantiacus (Phalangiidae, Opiliones) during winter diapause.
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Mirjanic-Azaric, B; Rizzo, M; Jürgens, G; Hallstroem, S; Srdic, S; Marc, J; Cerne, D Atorvastatin treatment increases plasma bilirubin but not HMOX1 expression in stable angina patients.
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Leis, HJ; Windischhofer, W Molecular characterisation of group IVA (cytosolic) phospholipase A2 in murine osteoblastic MC3T3-E1 cells.
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Silbernagel, G; Baumgartner, I; März, W Cardiovascular Safety of Plant Sterol and Stanol Consumption.
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Chennamsetty, I; Scharnagl, H; Kleber, ME; Marz, W; Kostner, GM Lipoprotein(a): when to measure and how to treat?
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Wruck, W; Kashofer, K; Rehman, S; Daskalaki, A; Berg, D; Gralka, E; Jozefczuk, J; Drews, K; Pandey, V; Regenbrecht, C; Wierling, C; Turano, P; Korf, U; Zatloukal, K; Lehrach, H; Westerhoff, HV; Adjaye, J Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes.
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Lee, JM; Wagner, M; Xiao, R; Kim, KH; Feng, D; Lazar, MA; Moore, DD Nutrient-sensing nuclear receptors coordinate autophagy.
Nature. 2014; 516(7529): 112-115. Doi: 10.1038/nature13961 [OPEN ACCESS]
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Oh, DY; Walenta, E; Akiyama, TE; Lagakos, WS; Lackey, D; Pessentheiner, AR; Sasik, R; Hah, N; Chi, TJ; Cox, JM; Powels, MA; Di Salvo, J; Sinz, C; Watkins, SM; Armando, AM; Chung, H; Evans, RM; Quehenberger, O; McNelis, J; Bogner-Strauss, JG; Olefsky, JM A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice.
Nat Med. 2014; 20(8): 942-947. Doi: 10.1038/nm.3614 [OPEN ACCESS]
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Demetz, E; Schroll, A; Auer, K; Heim, C; Patsch, JR; Eller, P; Theurl, M; Theurl, I; Theurl, M; Seifert, M; Lener, D; Stanzl, U; Haschka, D; Asshoff, M; Dichtl, S; Nairz, M; Huber, E; Stadlinger, M; Moschen, AR; Li, X; Pallweber, P; Scharnagl, H; Stojakovic, T; März, W; Kleber, ME; Garlaschelli, K; Uboldi, P; Catapano, AL; Stellaard, F; Rudling, M; Kuba, K; Imai, Y; Arita, M; Schuetz, JD; Pramstaller, PP; Tietge, UJF; Trauner, M; Norata, GD; Claudel, T; Hicks, AA; Weiss, G; Tancevski, I The arachidonic acid metabolome serves as a conserved regulator of cholesterol metabolism.
Cell Metab. 2014; 20(5):787-798 Doi: 10.1016/j.cmet.2014.09.004 [OPEN ACCESS]
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Walter, KM; Schönenberger, MJ; Trötzmüller, M; Horn, M; Elsässer, HP; Moser, AB; Lucas, MS; Schwarz, T; Gerber, PA; Faust, PL; Moch, H; Köfeler, HC; Krek, W; Kovacs, WJ Hif-2α promotes degradation of Mammalian peroxisomes by selective autophagy.
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Ljubojevic, S; Radulovic, S; Leitinger, G; Sedej, S; Sacherer, M; Holzer, M; Winkler, C; Pritz, E; Mittler, T; Schmidt, A; Sereinigg, M; Wakula, P; Zissimopoulos, S; Bisping, E; Post, H; Marsche, G; Bossuyt, J; Bers, DM; Kockskämper, J; Pieske, B Early remodeling of perinuclear Ca2+ stores and nucleoplasmic Ca2+ signaling during the development of hypertrophy and heart failure.
Circulation. 2014; 130(3):244-255 Doi: 10.1161/CIRCULATIONAHA.114.008927 [OPEN ACCESS]
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Scharnagl, H; Kleber, ME; März, W Letter by scharnagl et Al regarding article, "elevated remnant cholesterol causes both low-grade inflammation and ischemic heart disease, whereas elevated low-density lipoprotein cholesterol causes ischemic heart disease without inflammation".
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Schicho, R; Storr, M IBD: Patients with IBD find symptom relief in the Cannabis field.
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García-Rodríguez, JL; Barbier-Torres, L; Fernández-Álvarez, S; Gutiérrez-de Juan, V; Monte, MJ; Halilbasic, E; Herranz, D; Álvarez, L; Aspichueta, P; Marín, JJ; Trauner, M; Mato, JM; Serrano, M; Beraza, N; Martínez-Chantar, ML SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling.
Hepatology. 2014; 59(5):1972-1983 Doi: 10.1002/hep.26971 [OPEN ACCESS]
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Jha, P; Claudel, T; Baghdasaryan, A; Mueller, M; Halilbasic, E; Das, SK; Lass, A; Zimmermann, R; Zechner, R; Hoefler, G; Trauner, M Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia.
Hepatology. 2014; 59(3):858-869 Doi: 10.1002/hep.26732 [OPEN ACCESS]
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Kucukoglu, O; Guldiken, N; Chen, Y; Usachov, V; El-Heliebi, A; Haybaeck, J; Denk, H; Trautwein, C; Strnad, P High-fat diet triggers Mallory-Denk body formation through misfolding and crosslinking of excess keratin 8.
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Step, SE; Lim, HW; Marinis, JM; Prokesch, A; Steger, DJ; You, SH; Won, KJ; Lazar, MA Anti-diabetic rosiglitazone remodels the adipocyte transcriptome by redistributing transcription to PPARγ-driven enhancers.
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Stradner, MH; Gruber, G; Angerer, H; Huber, V; Setznagl, D; Kremser, ML; Fürst, FC; Windhager, R; Graninger, WB A5.9 Sphingosine-1-phosphate counteracts interleukin-1β in human chondrocytes.
Ann Rheum Dis. . 2014; 73 Suppl 1: A66-A67.-European Workshop for Rheumatology Research; FEB 20-22, 2014; Lissbon, PORTUGAL. Doi: 10.1136/annrheumdis-2013-205124.151 [Poster]
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Fuchs, CD; Claudel, T; Trauner, M Role of metabolic lipases and lipolytic metabolites in the pathogenesis of NAFLD.
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Zewinger, S; Speer, T; Kleber, ME; Scharnagl, H; Woitas, R; Lepper, PM; Pfahler, K; Seiler, S; Heine, GH; März, W; Silbernagel, G; Fliser, D HDL cholesterol is not associated with lower mortality in patients with kidney dysfunction.
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Bettermann, K; Hohensee, T; Haybaeck, J Steatosis and steatohepatitis: complex disorders.
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Kessler, SM; Simon, Y; Gemperlein, K; Gianmoena, K; Cadenas, C; Zimmer, V; Pokorny, J; Barghash, A; Helms, V; van Rooijen, N; Bohle, RM; Lammert, F; Hengstler, JG; Mueller, R; Haybaeck, J; Kiemer, AK Fatty acid elongation in non-alcoholic steatohepatitis and hepatocellular carcinoma.
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Kvaternik, H; Wanek, T; Hammerschmidt, F; Zolle, I; Aigner, R; Kuntner, C Radiosynthesis of [124I]iodometomidate and biological evaluation using small-animal PET.
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Scharnagl, H; Heuschneider, C; Sailer, S; Kleber, ME; März, W; Ritsch, A Decreased cholesterol efflux capacity in patients with low cholesteryl ester transfer protein plasma levels.
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Abumaree, MH; Brownbill, P; Burton, G; Castillo, C; Chamley, L; Croy, BA; Drewlo, S; Dunk, C; Girard, S; Hansson, S; Jones, S; Jurisicova, A; Lewis, R; Letarte, M; Parast, M; Pehrson, C; Rappolee, D; Schneider, H; Tannetta, D; Varmuza, S; Wadsack, C; Wallace, AE; Zenerino, C; Lash, GE IFPA Meeting 2013 Workshop Report III: maternal placental immunological interactions, novel determinants of trophoblast cell fate, dual ex vivo perfusion of the human placenta.
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Hoerl, G; Ledinski, G; Kager, G; Thalhammer, M; Koestenberger, M; Juergens, G; Gary, T; Cvirn, G Virtually same oxidizability of LDL but higher Lp(a) levels in arterial compared to venous plasma.
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Hörl, G; Ledinski, G; Kager, G; Hallström, S; Tafeit, E; Koestenberger, M; Jürgens, G; Cvirn, G In vitro oxidation of LDL by ozone.
Chem Phys Lipids. 2014; 183(7):18-21 Doi: 10.1016/j.chemphyslip.2014.05.002
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Simon, Y; Kessler, SM; Gemperlein, K; Bohle, RM; Müller, R; Haybaeck, J; Kiemer, AK Elevated free cholesterol in a p62 overexpression model of non-alcoholic steatohepatitis.
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Rossmann, C; Windpassinger, C; Brunner, D; Kovacevic, A; Schweighofer, N; Malli, R; Schuligoi, R; Prokesch, A; Kluve-Beckerman, B; Graier, WF; Kratky, D; Sattler, W; Malle, E Characterization of rat serum amyloid A4 (SAA4): a novel member of the SAA superfamily.
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Trauner, M; Halilbasic, E; Kazemi-Shirazi, L; Kienbacher, C; Staufer, K; Traussnigg, S; Hofer, H Therapeutic role of bile acids and nuclear receptor agonists in fibrosing cholangiopathies.
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Schweiger, M; Eichmann, TO; Taschler, U; Zimmermann, R; Zechner, R; Lass, A Measurement of lipolysis.
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Raspotnig, G; Schaider, M; Stabentheiner, E; Leis, HJ; Karaman, I On the enigmatic scent glands of dyspnoan harvestmen (Arachnida, Opiliones): first evidence for the production of volatile secretions.
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Silbernagel, G; Baumgartner, I; Wanner, C; März, W Toward individualized cholesterol-lowering treatment in end-stage renal disease.
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Luschnig, P; Frei, R; Lang-Loidolt, D; Rozsasi, A; Tomazic, PV; Lippe, IT; Schuligoi, R; Heinemann, A Altered inhibitory function of the E-type prostanoid receptor 4 in eosinophils and monocytes from aspirin-intolerant patients.
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Schicho, R; Storr, M Cannabis finds its way into treatment of Crohn's disease.
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Graulich, T; Das, SK; Wessels, L; Kummer, W; Hoefler, G; Mühlfeld, C Effects of Lewis lung carcinoma and B16 melanoma on the innervation of the mouse trachea.
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Zinrajh, D; Hörl, G; Jürgens, G; Marc, J; Sok, M; Cerne, D Increased phosphatidylethanolamine N-methyltransferase gene expression in non-small-cell lung cancer tissue predicts shorter patient survival.
Oncol Lett. 2014; 7(6):2175-2179 Doi: 10.3892/ol.2014.2035 [OPEN ACCESS]
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Wanner, C; März, W; Varushchanka, A; Apanasovich, N; Dosta, N; Yakubtsevich, R; Locatelli, F Dyslipidemia in chronic kidney disease: randomized controlled trial of colestilan versus simvastatin in dialysis patients.
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Klose, G; Beil, FU; Dieplinger, H; von Eckardstein, A; Föger, B; Gouni-Berthold, I; Heigl, F; Koenig, W; Kostner, GM; Landmesser, U; Laufs, U; Leistikow, F; März, W; Noll, G; Parhofer, KG; Paulweber, B; Riesen, WF; Schaefer, JR; Steinhagen-Thiessen, E; Steinmetz, A; Toplak, H; Wanner, C; Windler, E; American Heart Association, American College of Cardiology New AHA and ACC guidelines on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk.
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Klose, G; Beil, FU; Dieplinger, H; von Eckardstein, A; Föger, B; Gouni-Berthold, I; Koenig, W; Kostner, GM; Landmesser, U; Laufs, U; Leistikow, F; März, W; Merkel, M; Müller-Wieland, D; Noll, G; Parhofer, KG; Paulweber, B; Riesen, W; Schaefer, JR; Steinhagen-Thiessen, E; Steinmetz, A; Toplak, H; Wanner, C; Windler, E [New AHA and ACC guidelines on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk : Statement of the D•A•CH Society for Prevention of Cardiovascular Diseases, the Austrian Atherosclerosis Society and the Working Group on Lipids and Atherosclerosis (AGLA) of the Swiss Society for Cardiology].
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Karbiener, M; Scheideler, M MicroRNA Functions in Brite/Brown Fat - Novel Perspectives towards Anti-Obesity Strategies.
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Konya, V; Peinhaupt, M; Heinemann, A Adhesion of eosinophils to endothelial cells or substrates under flow conditions.
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Wichro, E; Macheiner, T; Schmid, J; Kavsek, B; Sargsyan, K The Wide and Complex Field of NAFLD Biomarker Research: Trends.
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2013

Do, R; Willer, CJ; Schmidt, EM; Sengupta, S; Gao, C; Peloso, GM; Gustafsson, S; Kanoni, S; Ganna, A; Chen, J; Buchkovich, ML; Mora, S; Beckmann, JS; Bragg-Gresham, JL; Chang, HY; Demirkan, A; Den Hertog, HM; Donnelly, LA; Ehret, GB; Esko, T; Feitosa, MF; Ferreira, T; Fischer, K; Fontanillas, P; Fraser, RM; Freitag, DF; Gurdasani, D; Heikkilä, K; Hyppönen, E; Isaacs, A; Jackson, AU; Johansson, A; Johnson, T; Kaakinen, M; Kettunen, J; Kleber, ME; Li, X; Luan, J; Lyytikäinen, LP; Magnusson, PK; Mangino, M; Mihailov, E; Montasser, ME; Müller-Nurasyid, M; Nolte, IM; O'Connell, JR; Palmer, CD; Perola, M; Petersen, AK; Sanna, S; Saxena, R; Service, SK; Shah, S; Shungin, D; Sidore, C; Song, C; Strawbridge, RJ; Surakka, I; Tanaka, T; Teslovich, TM; Thorleifsson, G; Van den Herik, EG; Voight, BF; Volcik, KA; Waite, LL; Wong, A; Wu, Y; Zhang, W; Absher, D; Asiki, G; Barroso, I; Been, LF; Bolton, JL; Bonnycastle, LL; Brambilla, P; Burnett, MS; Cesana, G; Dimitriou, M; Doney, AS; Döring, A; Elliott, P; Epstein, SE; Eyjolfsson, GI; Gigante, B; Goodarzi, MO; Grallert, H; Gravito, ML; Groves, CJ; Hallmans, G; Hartikainen, AL; Hayward, C; Hernandez, D; Hicks, AA; Holm, H; Hung, YJ; Illig, T; Jones, MR; Kaleebu, P; Kastelein, JJ; Khaw, KT; Kim, E; Klopp, N; Komulainen, P; Kumari, M; Langenberg, C; Lehtimäki, T; Lin, SY; Lindström, J; Loos, RJ; Mach, F; McArdle, WL; Meisinger, C; Mitchell, BD; Müller, G; Nagaraja, R; Narisu, N; Nieminen, TV; Nsubuga, RN; Olafsson, I; Ong, KK; Palotie, A; Papamarkou, T; Pomilla, C; Pouta, A; Rader, DJ; Reilly, MP; Ridker, PM; Rivadeneira, F; Rudan, I; Ruokonen, A; Samani, N; Scharnagl, H; Seeley, J; Silander, K; Stančáková, A; Stirrups, K; Swift, AJ; Tiret, L; Uitterlinden, AG; van Pelt, LJ; Vedantam, S; Wainwright, N; Wijmenga, C; Wild, SH; Willemsen, G; Wilsgaard, T; Wilson, JF; Young, EH; Zhao, JH; Adair, LS; Arveiler, D; Assimes, TL; Bandinelli, S; Bennett, F; Bochud, M; Boehm, BO; Boomsma, DI; Borecki, IB; Bornstein, SR; Bovet, P; Burnier, M; Campbell, H; Chakravarti, A; Chambers, JC; Chen, YD; Collins, FS; Cooper, RS; Danesh, J; Dedoussis, G; de Faire, U; Feranil, AB; Ferrières, J; Ferrucci, L; Freimer, NB; Gieger, C; Groop, LC; Gudnason, V; Gyllensten, U; Hamsten, A; Harris, TB; Hingorani, A; Hirschhorn, JN; Hofman, A; Hovingh, GK; Hsiung, CA; Humphries, SE; Hunt, SC; Hveem, K; Iribarren, C; Järvelin, MR; Jula, A; Kähönen, M; Kaprio, J; Kesäniemi, A; Kivimaki, M; Kooner, JS; Koudstaal, PJ; Krauss, RM; Kuh, D; Kuusisto, J; Kyvik, KO; Laakso, M; Lakka, TA; Lind, L; Lindgren, CM; Martin, NG; März, W; McCarthy, MI; McKenzie, CA; Meneton, P; Metspalu, A; Moilanen, L; Morris, AD; Munroe, PB; Njølstad, I; Pedersen, NL; Power, C; Pramstaller, PP; Price, JF; Psaty, BM; Quertermous, T; Rauramaa, R; Saleheen, D; Salomaa, V; Sanghera, DK; Saramies, J; Schwarz, PE; Sheu, WH; Shuldiner, AR; Siegbahn, A; Spector, TD; Stefansson, K; Strachan, DP; Tayo, BO; Tremoli, E; Tuomilehto, J; Uusitupa, M; van Duijn, CM; Vollenweider, P; Wallentin, L; Wareham, NJ; Whitfield, JB; Wolffenbuttel, BH; Altshuler, D; Ordovas, JM; Boerwinkle, E; Palmer, CN; Thorsteinsdottir, U; Chasman, DI; Rotter, JI; Franks, PW; Ripatti, S; Cupples, LA; Sandhu, MS; Rich, SS; Boehnke, M; Deloukas, P; Mohlke, KL; Ingelsson, E; Abecasis, GR; Daly, MJ; Neale, BM; Kathiresan, S Common variants associated with plasma triglycerides and risk for coronary artery disease.
Nat Genet. 2013; 45(11):1345-1352 Doi: 10.1038/ng.2795 [OPEN ACCESS]
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Global Lipids Genetics Consortium; Willer, CJ; Schmidt, EM; Sengupta, S; Peloso, GM; Gustafsson, S; Kanoni, S; Ganna, A; Chen, J; Buchkovich, ML; Mora, S; Beckmann, JS; Bragg-Gresham, JL; Chang, HY; Demirkan, A; Den Hertog, HM; Do, R; Donnelly, LA; Ehret, GB; Esko, T; Feitosa, MF; Ferreira, T; Fischer, K; Fontanillas, P; Fraser, RM; Freitag, DF; Gurdasani, D; Heikkilä, K; Hyppönen, E; Isaacs, A; Jackson, AU; Johansson, A; Johnson, T; Kaakinen, M; Kettunen, J; Kleber, ME; Li, X; Luan, J; Lyytikäinen, LP; Magnusson, PK; Mangino, M; Mihailov, E; Montasser, ME; Müller-Nurasyid, M; Nolte, IM; O'Connell, JR; Palmer, CD; Perola, M; Petersen, AK; Sanna, S; Saxena, R; Service, SK; Shah, S; Shungin, D; Sidore, C; Song, C; Strawbridge, RJ; Surakka, I; Tanaka, T; Teslovich, TM; Thorleifsson, G; Van den Herik, EG; Voight, BF; Volcik, KA; Waite, LL; Wong, A; Wu, Y; Zhang, W; Absher, D; Asiki, G; Barroso, I; Been, LF; Bolton, JL; Bonnycastle, LL; Brambilla, P; Burnett, MS; Cesana, G; Dimitriou, M; Doney, AS; Döring, A; Elliott, P; Epstein, SE; Eyjolfsson, GI; Gigante, B; Goodarzi, MO; Grallert, H; Gravito, ML; Groves, CJ; Hallmans, G; Hartikainen, AL; Hayward, C; Hernandez, D; Hicks, AA; Holm, H; Hung, YJ; Illig, T; Jones, MR; Kaleebu, P; Kastelein, JJ; Khaw, KT; Kim, E; Klopp, N; Komulainen, P; Kumari, M; Langenberg, C; Lehtimäki, T; Lin, SY; Lindström, J; Loos, RJ; Mach, F; McArdle, WL; Meisinger, C; Mitchell, BD; Müller, G; Nagaraja, R; Narisu, N; Nieminen, TV; Nsubuga, RN; Olafsson, I; Ong, KK; Palotie, A; Papamarkou, T; Pomilla, C; Pouta, A; Rader, DJ; Reilly, MP; Ridker, PM; Rivadeneira, F; Rudan, I; Ruokonen, A; Samani, N; Scharnagl, H; Seeley, J; Silander, K; Stancáková, A; Stirrups, K; Swift, AJ; Tiret, L; Uitterlinden, AG; van Pelt, LJ; Vedantam, S; Wainwright, N; Wijmenga, C; Wild, SH; Willemsen, G; Wilsgaard, T; Wilson, JF; Young, EH; Zhao, JH; Adair, LS; Arveiler, D; Assimes, TL; Bandinelli, S; Bennett, F; Bochud, M; Boehm, BO; Boomsma, DI; Borecki, IB; Bornstein, SR; Bovet, P; Burnier, M; Campbell, H; Chakravarti, A; Chambers, JC; Chen, YD; Collins, FS; Cooper, RS; Danesh, J; Dedoussis, G; de Faire, U; Feranil, AB; Ferrières, J; Ferrucci, L; Freimer, NB; Gieger, C; Groop, LC; Gudnason, V; Gyllensten, U; Hamsten, A; Harris, TB; Hingorani, A; Hirschhorn, JN; Hofman, A; Hovingh, GK; Hsiung, CA; Humphries, SE; Hunt, SC; Hveem, K; Iribarren, C; Järvelin, MR; Jula, A; Kähönen, M; Kaprio, J; Kesäniemi, A; Kivimaki, M; Kooner, JS; Koudstaal, PJ; Krauss, RM; Kuh, D; Kuusisto, J; Kyvik, KO; Laakso, M; Lakka, TA; Lind, L; Lindgren, CM; Martin, NG; März, W; McCarthy, MI; McKenzie, CA; Meneton, P; Metspalu, A; Moilanen, L; Morris, AD; Munroe, PB; Njølstad, I; Pedersen, NL; Power, C; Pramstaller, PP; Price, JF; Psaty, BM; Quertermous, T; Rauramaa, R; Saleheen, D; Salomaa, V; Sanghera, DK; Saramies, J; Schwarz, PE; Sheu, WH; Shuldiner, AR; Siegbahn, A; Spector, TD; Stefansson, K; Strachan, DP; Tayo, BO; Tremoli, E; Tuomilehto, J; Uusitupa, M; van Duijn, CM; Vollenweider, P; Wallentin, L; Wareham, NJ; Whitfield, JB; Wolffenbuttel, BH; Ordovas, JM; Boerwinkle, E; Palmer, CN; Thorsteinsdottir, U; Chasman, DI; Rotter, JI; Franks, PW; Ripatti, S; Cupples, LA; Sandhu, MS; Rich, SS; Boehnke, M; Deloukas, P; Kathiresan, S; Mohlke, KL; Ingelsson, E; Abecasis, GR Discovery and refinement of loci associated with lipid levels.
Nat Genet. 2013; 45(11):1274-1283 Doi: 10.1038/ng.2797 [OPEN ACCESS]
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Silbernagel, G; Chapman, MJ; Genser, B; Kleber, ME; Fauler, G; Scharnagl, H; Grammer, TB; Boehm, BO; Mäkelä, KM; Kähönen, M; Carmena, R; Rietzschel, ER; Bruckert, E; Deanfield, JE; Miettinen, TA; Raitakari, OT; Lehtimäki, T; März, W High intestinal cholesterol absorption is associated with cardiovascular disease and risk alleles in ABCG8 and ABO: evidence from the LURIC and YFS cohorts and from a meta-analysis.
J Am Coll Cardiol. 2013; 62(4):291-299 Doi: 10.1016/j.jacc.2013.01.100 [OPEN ACCESS]
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Leebmann, J; Roeseler, E; Julius, U; Heigl, F; Spitthoever, R; Heutling, D; Breitenberger, P; Maerz, W; Lehmacher, W; Heibges, A; Klingel, R; Pro(a)LiFe Study Group* Lipoprotein apheresis in patients with maximally tolerated lipid-lowering therapy, lipoprotein(a)-hyperlipoproteinemia, and progressive cardiovascular disease: prospective observational multicenter study.
Circulation. 2013; 128(24):2567-2576 Doi: 10.1161/CIRCULATIONAHA.113.002432 [OPEN ACCESS]
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Sabater-Lleal, M; Huang, J; Chasman, D; Naitza, S; Dehghan, A; Johnson, AD; Teumer, A; Reiner, AP; Folkersen, L; Basu, S; Rudnicka, AR; Trompet, S; Mälarstig, A; Baumert, J; Bis, JC; Guo, X; Hottenga, JJ; Shin, SY; Lopez, LM; Lahti, J; Tanaka, T; Yanek, LR; Oudot-Mellakh, T; Wilson, JF; Navarro, P; Huffman, JE; Zemunik, T; Redline, S; Mehra, R; Pulanic, D; Rudan, I; Wright, AF; Kolcic, I; Polasek, O; Wild, SH; Campbell, H; Curb, JD; Wallace, R; Liu, S; Eaton, CB; Becker, DM; Becker, LC; Bandinelli, S; Räikkönen, K; Widen, E; Palotie, A; Fornage, M; Green, D; Gross, M; Davies, G; Harris, SE; Liewald, DC; Starr, JM; Williams, FM; Grant, PJ; Spector, TD; Strawbridge, RJ; Silveira, A; Sennblad, B; Rivadeneira, F; Uitterlinden, AG; Franco, OH; Hofman, A; van Dongen, J; Willemsen, G; Boomsma, DI; Yao, J; Swords Jenny, N; Haritunians, T; McKnight, B; Lumley, T; Taylor, KD; Rotter, JI; Psaty, BM; Peters, A; Gieger, C; Illig, T; Grotevendt, A; Homuth, G; Völzke, H; Kocher, T; Goel, A; Franzosi, MG; Seedorf, U; Clarke, R; Steri, M; Tarasov, KV; Sanna, S; Schlessinger, D; Stott, DJ; Sattar, N; Buckley, BM; Rumley, A; Lowe, GD; McArdle, WL; Chen, MH; Tofler, GH; Song, J; Boerwinkle, E; Folsom, AR; Rose, LM; Franco-Cereceda, A; Teichert, M; Ikram, MA; Mosley, TH; Bevan, S; Dichgans, M; Rothwell, PM; Sudlow, CL; Hopewell, JC; Chambers, JC; Saleheen, D; Kooner, JS; Danesh, J; Nelson, CP; Erdmann, J; Reilly, MP; Kathiresan, S; Schunkert, H; Morange, PE; Ferrucci, L; Eriksson, JG; Jacobs, D; Deary, IJ; Soranzo, N; Witteman, JC; de Geus, EJ; Tracy, RP; Hayward, C; Koenig, W; Cucca, F; Jukema, JW; Eriksson, P; Seshadri, S; Markus, HS; Watkins, H; Samani, NJ; VTE Consortium; STROKE Consortium; Wellcome Trust Case Control Consortium 2 (WTCCC2); C4D Consortium; CARDIoGRAM Consortium; Wallaschofski, H; Smith, NL; Tregouet, D; Ridker, PM; Tang, W; Strachan, DP; Hamsten, A; O'Donnell, CJ Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.
Circulation. 2013; 128(12):1310-1324 Doi: 10.1161/CIRCULATIONAHA.113.002251 [OPEN ACCESS]
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Grammer, TB; Hoffmann, MM; Scharnagl, H; Kleber, ME; Silbernagel, G; Pilz, S; Tomaschitz, A; Lerchbaum, E; Siekmeier, R; März, W Smoking, apolipoprotein E genotypes, and mortality (the Ludwigshafen RIsk and Cardiovascular Health study).
Eur Heart J. 2013; 34(17):1298-1305 Doi: 10.1093/eurheartj/eht001 [OPEN ACCESS]
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Kostner, KM; März, W; Kostner, GM When should we measure lipoprotein (a)?
Eur Heart J. 2013; 34(42):3268-3276 Doi: 10.1093/eurheartj/eht053 [OPEN ACCESS]
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Silbernagel, G; Schöttker, B; Appelbaum, S; Scharnagl, H; Kleber, ME; Grammer, TB; Ritsch, A; Mons, U; Holleczek, B; Goliasch, G; Niessner, A; Boehm, BO; Schnabel, RB; Brenner, H; Blankenberg, S; Landmesser, U; März, W High-density lipoprotein cholesterol, coronary artery disease, and cardiovascular mortality.
Eur Heart J. 2013; 34(46):3563-3571 Doi: 10.1093/eurheartj/eht343 [OPEN ACCESS]
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Ho, JE; Chen, WY; Chen, MH; Larson, MG; McCabe, EL; Cheng, S; Ghorbani, A; Coglianese, E; Emilsson, V; Johnson, AD; Walter, S; Franceschini, N; O'Donnell, CJ; CARDIoGRAM Consortium; CHARGE Inflammation Working Group; Dehghan, A; Lu, C; Levy, D; Newton-Cheh, C; CHARGE Heart Failure Working Group; Lin, H; Felix, JF; Schreiter, ER; Vasan, RS; Januzzi, JL; Lee, RT; Wang, TJ; Assimes, TL; Deloukas, P; Erdmann, J; Holm, H; Kathiresan, S; König, IR; McPherson, R; Reilly, MP; Roberts, R; Samani, NJ; Schunkert, H; Stewart, AF Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling.
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Eibinger, G; Fauler, G; Bernhart, E; Frank, S; Hammer, A; Wintersperger, A; Eder, H; Heinemann, A; Mischel, PS; Malle, E; Sattler, W On the role of 25-hydroxycholesterol synthesis by glioblastoma cell lines. Implications for chemotactic monocyte recruitment.
Exp Cell Res. 2013; 319(12):1828-1838 Doi: 10.1016/j.yexcr.2013.03.025 [OPEN ACCESS]
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Huang, X; Baumann, M; Nikitina, L; Wenger, F; Surbek, D; Körner, M; Albrecht, C RNA degradation differentially affects quantitative mRNA measurements of endogenous reference genes in human placenta.
Placenta. 2013; 34(7):544-547 Doi: 10.1016/j.placenta.2013.03.011
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Porpaczy, E; Tauber, S; Bilban, M; Kostner, G; Gruber, M; Eder, S; Heintel, D; Le, T; Fleiss, K; Skrabs, C; Shehata, M; Jager, U; Vanura, K; Lipoprotein lipase in chronic lymphocytic leukaemia - Strong biomarker with lack of functional significance.
LEUK RES. 2013; 37(6): 631-636. Doi: 10.1016/j.leukres.2013.02.008 [OPEN ACCESS]
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Fauland, A; Trotzmuller, M; Eberl, A; Afiuni-Zadeh, S; Kofeler, H; Guo, XH; Lankmayr, E; An improved SPE method for fractionation and identification of phospholipids.
J Sep Sci. 2013; 36(4):744-751 Doi: 10.1002/jssc.201200708
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Stefulj, J; Peric, M; Malnar, M; Kosicek, M; Schweinzer, C; Zivkovic, J; Scholler, M; Panzenboeck, U; Hecimovic, S Pharmacological activation of LXRs decreases amyloid-β levels in Niemann-Pick type C model cells.
Curr Pharm Biotechnol. 2013; 14(6):582-593 Doi: 10.2174/138920101131400224
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Waltl-Patankar, S; Patankar, J; Fauler, G; Nusshold, C; Ullen, A; Eibinger, G; Wintersperger, A; Kratky, D; Malle, E; Sattler, W 25-Hydroxycholesterol regulates cholesterol homeostasis in the murine CATH.a neuronal cell line.
Neurosci Lett. 2013; 539(4):16-21 Doi: 10.1016/j.neulet.2013.01.014 [OPEN ACCESS]
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Radulovic, M; Knittelfelder, O; Cristobal-Sarramian, A; Kolb, D; Wolinski, H; Kohlwein, SD The emergence of lipid droplets in yeast: current status and experimental approaches.
Curr Genet. 2013; 59(4):231-242 Doi: 10.1007/s00294-013-0407-9 [OPEN ACCESS]
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Stefulj, J; Panzenboeck, U; Hof, PR; Simic, G; Pathogenesis, modulation, and therapy of Alzheimer's disease: A perspective on roles of liver-X receptors.
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Suvajdzic, L; Leovac, V; Joksovic, M; Bogdanovic, G; Kojic, V; Vujic, N; Mrdja, T; Kocic, B; Antimicrobial Activity of Copper (II) Complex with 1,2-bis [(1,3-diphenylpyrazol-4-yl)methyl] Diaminoethane.
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Schaller, S; Willmann, S; Lippert, J; Schaupp, L; Pieber, TR; Schuppert, A; Eissing, T A Generic Integrated Physiologically based Whole-body Model of the Glucose-Insulin-Glucagon Regulatory System.
CPT Pharmacometrics Syst Pharmacol. 2013; 2(1):e65-e65 Doi: 10.1038/psp.2013.40 [OPEN ACCESS]
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2012

Kumari, M; Schoiswohl, G; Chitraju, C; Paar, M; Cornaciu, I; Rangrez, AY; Wongsiriroj, N; Nagy, HM; Ivanova, PT; Scott, SA; Knittelfelder, O; Rechberger, GN; Birner-Gruenberger, R; Eder, S; Brown, HA; Haemmerle, G; Oberer, M; Lass, A; Kershaw, EE; Zimmermann, R; Zechner, R Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase.
Cell Metab. 2012; 15(5):691-702 Doi: 10.1016/j.cmet.2012.04.008 [OPEN ACCESS]
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Grallert, H; Dupuis, J; Bis, JC; Dehghan, A; Barbalic, M; Baumert, J; Lu, C; Smith, NL; Uitterlinden, AG; Roberts, R; Khuseyinova, N; Schnabel, RB; Rice, KM; Rivadeneira, F; Hoogeveen, RC; Fontes, JD; Meisinger, C; Keaney, JF; Lemaitre, R; Aulchenko, YS; Vasan, RS; Ellis, S; Hazen, SL; van Duijn, CM; Nelson, JJ; März, W; Schunkert, H; McPherson, RM; Stirnadel-Farrant, HA; Psaty, BM; Gieger, C; Siscovick, D; Hofman, A; Illig, T; Cushman, M; Yamamoto, JF; Rotter, JI; Larson, MG; Stewart, AF; Boerwinkle, E; Witteman, JC; Tracy, RP; Koenig, W; Benjamin, EJ; Ballantyne, CM Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.
EUR HEART J. 2012; 33(2): 238-251. Doi: 10.1093/eurheartj/ehr372 [OPEN ACCESS]
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von Haehling, S; Schefold, JC; Jankowska, EA; Springer, J; Vazir, A; Kalra, PR; Sandek, A; Fauler, G; Stojakovic, T; Trauner, M; Ponikowski, P; Volk, HD; Doehner, W; Coats, AJ; Poole-Wilson, PA; Anker, SD Ursodeoxycholic acid in patients with chronic heart failure: a double-blind, randomized, placebo-controlled, crossover trial.
J Am Coll Cardiol. 2012; 59(6): 585-592. Doi: 10.1016/j.jacc.2011.10.880 [OPEN ACCESS]
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Blättermann, S; Peters, L; Ottersbach, PA; Bock, A; Konya, V; Weaver, CD; Gonzalez, A; Schröder, R; Tyagi, R; Luschnig, P; Gäb, J; Hennen, S; Ulven, T; Pardo, L; Mohr, K; Gütschow, M; Heinemann, A; Kostenis, E A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer.
Nat Chem Biol. 2012; 8(7):631-638 Doi: 10.1038/nchembio.962
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Moustafa, T; Fickert, P; Magnes, C; Guelly, C; Thueringer, A; Frank, S; Kratky, D; Sattler, W; Reicher, H; Sinner, F; Gumhold, J; Silbert, D; Fauler, G; Höfler, G; Lass, A; Zechner, R; Trauner, M Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.
Gastroenterology. 2012; 142(1):140-151 Doi: 10.1053/j.gastro.2011.09.051
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Sedej, M; Schröder, R; Bell, K; Platzer, W; Vukoja, A; Kostenis, E; Heinemann, A; Waldhoer, M D-type prostanoid receptor enhances the signaling of chemoattractant receptor-homologous molecule expressed on T(H)2 cells.
J Allergy Clin Immunol. 2012; 129(2): 500.e1- 500.e9 Doi: 10.1016/j.jaci.2011.08.015
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Fuchs, CD; Claudel, T; Kumari, P; Haemmerle, G; Pollheimer, MJ; Stojakovic, T; Scharnagl, H; Halilbasic, E; Gumhold, J; Silbert, D; Koefeler, H; Trauner, M Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice.
Hepatology. 2012; 56(1):270-280 Doi: 10.1002/hep.25601 [OPEN ACCESS]
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Quiroga, AD; Li, L; Trötzmüller, M; Nelson, R; Proctor, SD; Köfeler, H; Lehner, R Deficiency of carboxylesterase 1/esterase-x results in obesity, hepatic steatosis, and hyperlipidemia.
Hepatology. 2012; 56(6):2188-2198 Doi: 10.1002/hep.25961 [OPEN ACCESS]
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Asselbergs, FW; Guo, Y; van Iperen, EP; Sivapalaratnam, S; Tragante, V; Lanktree, MB; Lange, LA; Almoguera, B; Appelman, YE; Barnard, J; Baumert, J; Beitelshees, AL; Bhangale, TR; Chen, YD; Gaunt, TR; Gong, Y; Hopewell, JC; Johnson, T; Kleber, ME; Langaee, TY; Li, M; Li, YR; Liu, K; McDonough, CW; Meijs, MF; Middelberg, RP; Musunuru, K; Nelson, CP; O'Connell, JR; Padmanabhan, S; Pankow, JS; Pankratz, N; Rafelt, S; Rajagopalan, R; Romaine, SP; Schork, NJ; Shaffer, J; Shen, H; Smith, EN; Tischfield, SE; van der Most, PJ; van Vliet-Ostaptchouk, JV; Verweij, N; Volcik, KA; Zhang, L; Bailey, KR; Bailey, KM; Bauer, F; Boer, JM; Braund, PS; Burt, A; Burton, PR; Buxbaum, SG; Chen, W; Cooper-Dehoff, RM; Cupples, LA; deJong, JS; Delles, C; Duggan, D; Fornage, M; Furlong, CE; Glazer, N; Gums, JG; Hastie, C; Holmes, MV; Illig, T; Kirkland, SA; Kivimaki, M; Klein, R; Klein, BE; Kooperberg, C; Kottke-Marchant, K; Kumari, M; LaCroix, AZ; Mallela, L; Murugesan, G; Ordovas, J; Ouwehand, WH; Post, WS; Saxena, R; Scharnagl, H; Schreiner, PJ; Shah, T; Shields, DC; Shimbo, D; Srinivasan, SR; Stolk, RP; Swerdlow, DI; Taylor, HA; Topol, EJ; Toskala, E; van Pelt, JL; van Setten, J; Yusuf, S; Whittaker, JC; Zwinderman, AH; LifeLines Cohort Study; Anand, SS; Balmforth, AJ; Berenson, GS; Bezzina, CR; Boehm, BO; Boerwinkle, E; Casas, JP; Caulfield, MJ; Clarke, R; Connell, JM; Cruickshanks, KJ; Davidson, KW; Day, IN; de Bakker, PI; Doevendans, PA; Dominiczak, AF; Hall, AS; Hartman, CA; Hengstenberg, C; Hillege, HL; Hofker, MH; Humphries, SE; Jarvik, GP; Johnson, JA; Kaess, BM; Kathiresan, S; Koenig, W; Lawlor, DA; März, W; Melander, O; Mitchell, BD; Montgomery, GW; Munroe, PB; Murray, SS; Newhouse, SJ; Onland-Moret, NC; Poulter, N; Psaty, B; Redline, S; Rich, SS; Rotter, JI; Schunkert, H; Sever, P; Shuldiner, AR; Silverstein, RL; Stanton, A; Thorand, B; Trip, MD; Tsai, MY; van der Harst, P; van der Schoot, E; van der Schouw, YT; Verschuren, WM; Watkins, H; Wilde, AA; Wolffenbuttel, BH; Whitfield, JB; Hovingh, GK; Ballantyne, CM; Wijmenga, C; Reilly, MP; Martin, NG; Wilson, JG; Rader, DJ; Samani, NJ; Reiner, AP; Hegele, RA; Kastelein, JJ; Hingorani, AD; Talmud, PJ; Hakonarson, H; Elbers, CC; Keating, BJ; Drenos, F Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
Am J Hum Genet. 2012; 91(5):823-838 Doi: 10.1016/j.ajhg.2012.08.032 [OPEN ACCESS]
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Bechmann, LP; Hannivoort, RA; Gerken, G; Hotamisligil, GS; Trauner, M; Canbay, A The interaction of hepatic lipid and glucose metabolism in liver diseases.
J Hepatol. 2012; 56(4):952-964 Doi: 10.1016/j.jhep.2011.08.025 [OPEN ACCESS]
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Patankar, JV; Obrowsky, S; Doddapattar, P; Hoefler, G; Battle, M; Levak-Frank, S; Kratky, D Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis.
J Hepatol. 2012; 57(5):1061-1068 Doi: 10.1016/j.jhep.2012.06.028 [OPEN ACCESS]
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Chen, Y; Jacamo, R; Shi, YX; Wang, RY; Battula, VL; Konoplev, S; Strunk, D; Hofmann, NA; Reinisch, A; Konopleva, M; Andreeff, M Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment.
Blood. 2012; 119(21):4971-4980 Doi: 10.1182/blood-2011-11-389957 [OPEN ACCESS]
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Schittmayer, M; Birner-Gruenberger, R Lipolytic proteomics.
Mass Spectrom Rev. 2012; 31(5):570-582 Doi: 10.1002/mas.20355
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El-Gamal, D; Holzer, M; Gauster, M; Schicho, R; Binder, V; Konya, V; Wadsack, C; Schuligoi, R; Heinemann, A; Marsche, G Cyanate is a novel inducer of endothelial icam-1 expression.
Antioxid Redox Signal. 2012; 16(2): 129-137. Doi: 10.1089/ars.2011.4090 [OPEN ACCESS]
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Holzer, M; Zangger, K; El-Gamal, D; Binder, V; Curcic, S; Konya, V; Schuligoi, R; Heinemann, A; Marsche, G Myeloperoxidase-derived chlorinating species induce protein carbamylation through decomposition of thiocyanate and urea: novel pathways generating dysfunctional high-density lipoprotein.
Antioxid Redox Signal. 2012; 17(8):1043-1052 Doi: 10.1089/ars.2011.4403 [OPEN ACCESS]
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von Haehling, S; Stojakovic, T; Bigalke, B Copeptin--a novel marker in acute myocardial infarction.
Clin Chem. 2012; 58(1): 307-309. Doi: 10.1373/clinchem.2011.173658 [OPEN ACCESS]
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Scholler, M; Wadsack, C; Lang, I; Etschmaier, K; Schweinzer, C; Marsche, G; Dieber-Rotheneder, M; Desoye, G; Panzenboeck, U Phospholipid transfer protein in the placental endothelium is affected by gestational diabetes mellitus.
J Clin Endocrinol Metab. 2012; 97(2): 437-445. Doi: 10.1210/jc.2011-1942 [OPEN ACCESS]
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Scholler, M; Wadsack, C; Metso, J; Chirackal Manavalan, AP; Sreckovic, I; Schweinzer, C; Hiden, U; Jauhiainen, M; Desoye, G; Panzenboeck, U Phospholipid Transfer Protein Is Differentially Expressed in Human Arterial and Venous Placental Endothelial Cells and Enhances Cholesterol Efflux to Fetal HDL.
J Clin Endocrinol Metab. 2012; 97(7):2466-2474 Doi: 10.1210/jc.2011-2969 [OPEN ACCESS]
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Chennamsetty, I; Claudel, T; Kostner, KM; Trauner, M; Kostner, GM FGF19 signaling cascade suppresses APOA gene expression.
Arterioscler Thromb Vasc Biol. 2012; 32(5):1220-1227 Doi: 10.1161/ATVBAHA.111.243055 [OPEN ACCESS]
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Vaculik, C; Schuster, C; Bauer, W; Iram, N; Pfisterer, K; Kramer, G; Reinisch, A; Strunk, D; Elbe-Bürger, A Human dermis harbors distinct mesenchymal stromal cell subsets.
J Invest Dermatol. 2012; 132(3 Pt 1):563-574 Doi: 10.1038/jid.2011.355 [OPEN ACCESS]
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Aflaki, E; Doddapattar, P; Radovic, B; Povoden, S; Kolb, D; Vujic, N; Wegscheider, M; Koefeler, H; Hornemann, T; Graier, WF; Malli, R; Madeo, F; Kratky, D C16 ceramide is crucial for triacylglycerol-induced apoptosis in macrophages.
Cell Death Dis. 2012; 3(6):e280-e280 Doi: 10.1038/cddis.2012.17 [OPEN ACCESS]
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Tamilarasan, KP; Temmel, H; Das, SK; Al Zoughbi, W; Schauer, S; Vesely, PW; Hoefler, G Skeletal muscle damage and impaired regeneration due to LPL-mediated lipotoxicity.
Cell Death Dis. 2012; 3(11):e354-e354 Doi: 10.1038/cddis.2012.91 [OPEN ACCESS]
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Porubsky, S; Speak, AO; Salio, M; Jennemann, R; Bonrouhi, M; Zafarulla, R; Singh, Y; Dyson, J; Luckow, B; Lehuen, A; Malle, E; Müthing, J; Platt, FM; Cerundolo, V; Gröne, HJ Globosides but not isoglobosides can impact the development of invariant NKT cells and their interaction with dendritic cells.
J Immunol. 2012; 189(6):3007-3017 Doi: 10.4049/jimmunol.1201483 [OPEN ACCESS]
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Schicho, R; Storr, M A potential role for GPR55 in gastrointestinal functions.
Curr Opin Pharmacol. 2012; 12(6):653-658 Doi: 10.1016/j.coph.2012.09.009 [OPEN ACCESS]
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Crnkovic, S; Riederer, M; Lechleitner, M; Hallström, S; Malli, R; Graier, WF; Lindenmann, J; Popper, H; Olschewski, H; Olschewski, A; Frank, S Docosahexaenoic acid-induced unfolded protein response, cell cycle arrest, and apoptosis in vascular smooth muscle cells are triggered by Ca²⁺-dependent induction of oxidative stress.
Free Radic Biol Med. 2012; 52(9):1786-1795 Doi: 10.1016/j.freeradbiomed.2012.02.036 [OPEN ACCESS]
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Rees, MD; Dang, L; Thai, T; Owen, DM; Malle, E; Thomas, SR Targeted subendothelial matrix oxidation by myeloperoxidase triggers myosin II-dependent de-adhesion and alters signaling in endothelial cells.
Free Radic Biol Med. 2012; 53(12):2344-2356 Doi: 10.1016/j.freeradbiomed.2012.10.002 [OPEN ACCESS]
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Ullen, A; Fauler, G; Bernhart, E; Nusshold, C; Reicher, H; Leis, HJ; Malle, E; Sattler, W Phloretin ameliorates 2-chlorohexadecanal-mediated brain microvascular endothelial cell dysfunction in vitro.
Free Radic Biol Med. 2012; 53(9):1770-1781 Doi: 10.1016/j.freeradbiomed.2012.08.575 [OPEN ACCESS]
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Kargl, J; Balenga, NA; Platzer, W; Martini, L; Whistler, JL; Waldhoer, M The GPCR-associated sorting protein 1 regulates ligand-induced down-regulation of GPR55.
Br J Pharmacol. 2012; 165(8):2611-2619 Doi: 10.1111/j.1476-5381.2011.01562.x [OPEN ACCESS]
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Haange, SB; Oberbach, A; Schlichting, N; Hugenholtz, F; Smidt, H; von Bergen, M; Till, H; Seifert, J Metaproteome analysis and molecular genetics of rat intestinal microbiota reveals section and localization resolved species distribution and enzymatic functionalities.
J Proteome Res. 2012; 11(11):5406-5417 Doi: 10.1021/pr3006364
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Kroepfl, JM; Pekovits, K; Stelzer, I; Fuchs, R; Zelzer, S; Hofmann, P; Sedlmayr, P; Dohr, G; Wallner-Liebmann, S; Domej, W; Mueller, W Exercise increases the frequency of circulating hematopoietic progenitor cells, but reduces hematopoietic colony-forming capacity.
Stem Cells Dev. 2012; 21(16):2915-25 Doi: 10.1089/scd.2012.0017
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Kargl, J; Balenga, N; Parzmair, GP; Brown, AJ; Heinemann, A; Waldhoer, M The cannabinoid receptor CB1 modulates the signaling properties of the lysophosphatidylinositol receptor GPR55.
J Biol Chem. 2012; 287(53):44234-44248 Doi: 10.1074/jbc.M112.364109 [OPEN ACCESS]
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Khan, MJ; Alam, MR; Waldeck-Weiermair, M; Karsten, F; Groschner, L; Riederer, M; Hallstroem, S; Rockenfeller, P; Konya, V; Heinemann, A; Madeo, F; Graier, WF; Malli, R Inhibition of autophagy rescues palmitic acid induced necroptosis of endothelial cells.
J Biol Chem. 2012; 287(25):21110-21120 Doi: 10.1074/jbc.M111.319129 [OPEN ACCESS]
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Paar, M; Jüngst, C; Steiner, NA; Magnes, C; Sinner, F; Kolb, D; Lass, A; Zimmermann, R; Zumbusch, A; Kohlwein, SD; Wolinski, H Remodeling of lipid droplets during lipolysis and growth in adipocytes.
J Biol Chem. 2012; 287(14):11164-11173 Doi: 10.1074/jbc.M111.316794 [OPEN ACCESS]
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Leis, HJ; Donnarumma, F; Wintersteiger, R; Lazarus, R; Braml, B; Ortner, A; Windischhofer, W Bis-pentafluorobenzyl derivatives of N-acetyl-l-methionine and N-acetyl-l-selenomethionine for the quantitative determination in human plasma by gas chromatography-negative ion chemical ionisation mass spectrometry.
J Chromatogr A. 2012; 1242(9):92-100 Doi: 10.1016/j.chroma.2012.04.028
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Chennamsetty, I; Kostner, KM; Claudel, T; Vinod, M; Frank, S; Weiss, TS; Trauner, M; Kostner, GM Nicotinic acid inhibits hepatic APOA gene expression: studies in humans and in transgenic mice.
J Lipid Res. 2012; 53(11):2405-2412 Doi: 10.1194/jlr.M029769 [OPEN ACCESS]
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Chitraju, C; Trotzmuller, M; Hartler, J; Wolinski, H; Thallinger, GG; Lass, A; Zechner, R; Zimmermann, R; Kofeler, HC; Spener, F; Lipidomic analysis of lipid droplets from murine hepatocytes reveals distinct signatures for nutritional stress.
J Lipid Res. 2012; 53(10):2141-2152 Doi: 10.1194/jlr.M028902 [OPEN ACCESS]
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Holzer, M; Wolf, P; Curcic, S; Birner-Gruenberger, R; Weger, W; Inzinger, M; El-Gamal, D; Wadsack, C; Heinemann, A; Marsche, G Psoriasis alters HDL composition and cholesterol efflux capacity.
J Lipid Res. 2012; 53(8):1618-1624 Doi: 10.1194/jlr.M027367 [OPEN ACCESS]
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Schweiger, M; Paar, M; Eder, C; Brandis, J; Moser, E; Gorkiewicz, G; Grond, S; Radner, FP; Cerk, I; Cornaciu, I; Oberer, M; Kersten, S; Zechner, R; Zimmermann, R; Lass, A G0/G1 switch gene-2 regulates human adipocyte lipolysis by affecting activity and localization of adipose triglyceride lipase.
J Lipid Res. 2012; 53(11):2307-2317 Doi: 10.1194/jlr.M027409 [OPEN ACCESS]
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Obrowsky, S; Chandak, PG; Patankar, JV; Pfeifer, T; Povoden, S; Schreiber, R; Haemmerle, G; Levak-Frank, S; Kratky, D Cholesteryl ester accumulation and accelerated cholesterol absorption in intestine-specific hormone sensitive lipase-null mice.
Biochim Biophys Acta. 2012; 1821(11):1406-1414 Doi: 10.1016/j.bbalip.2012.07.013 [OPEN ACCESS]
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Rengachari, S; Bezerra, GA; Riegler-Berket, L; Gruber, CC; Sturm, C; Taschler, U; Boeszoermenyi, A; Dreveny, I; Zimmermann, R; Gruber, K; Oberer, M The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes.
Biochim Biophys Acta. 2012; 1821(7): 1012-1021. Doi: 10.1016/j.bbalip.2012.04.006 [OPEN ACCESS]
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Riederer, M; Köfeler, H; Lechleitner, M; Tritscher, M; Frank, S Impact of endothelial lipase on cellular lipid composition.
Biochim Biophys Acta. 2012; 1821(7):1003-1011 Doi: 10.1016/j.bbalip.2012.03.006 [OPEN ACCESS]
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Schreiber, R; Taschler, U; Preiss-Landl, K; Wongsiriroj, N; Zimmermann, R; Lass, A Retinyl ester hydrolases and their roles in vitamin A homeostasis.
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Stemmer, U; Ramprecht, C; Zenzmaier, E; Stojčić, B; Rechberger, G; Kollroser, M; Hermetter, A Uptake and protein targeting of fluorescent oxidized phospholipids in cultured RAW 264.7 macrophages.
Biochim Biophys Acta. 2012; 1821(4):706-718 Doi: 10.1016/j.bbalip.2012.01.014 [OPEN ACCESS]
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Damm, M; Nusshold, C; Cantillo, D; Rechberger, GN; Gruber, K; Sattler, W; Kappe, CO Can electromagnetic fields influence the structure and enzymatic digest of proteins? A critical evaluation of microwave-assisted proteomics protocols.
J Proteomics. 2012; 75(18):5533-5543 Doi: 10.1016/j.jprot.2012.07.043 [OPEN ACCESS]
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Gonzalo, H; Brieva, L; Tatzber, F; Jové, M; Cacabelos, D; Cassanyé, A; Lanau-Angulo, L; Boada, J; Serrano, JC; González, C; Hernández, L; Peralta, S; Pamplona, R; Portero-Otin, M Lipidome analysis in multiple sclerosis reveals protein lipoxidative damage as a potential pathogenic mechanism.
J Neurochem. 2012; 123(4): 622-634. Doi: 10.1111/j.1471-4159.2012.07934.x [OPEN ACCESS]
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Haybaeck, J; Stumptner, C; Thueringer, A; Kolbe, T; Magin, TM; Hesse, M; Fickert, P; Tsybrovskyy, O; Müller, H; Trauner, M; Zatloukal, K; Denk, H Genetic background effects of keratin 8 and 18 in a DDC-induced hepatotoxicity and Mallory-Denk body formation mouse model.
Lab Invest. 2012; 92(6):857-867 Doi: 10.1038/labinvest.2012.49 [OPEN ACCESS]
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Oberbach, A; Schlichting, N; Heinrich, M; Till, H; Stolzenburg, JU; Neuhaus, J Free fatty acid palmitate impairs the vitality and function of cultured human bladder smooth muscle cells.
PLoS One. 2012; 7(7):e41026-e41026 Doi: 10.1371/journal.pone.0041026 [OPEN ACCESS]
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Philipose, S; Konya, V; Lazarevic, M; Pasterk, LM; Marsche, G; Frank, S; Peskar, BA; Heinemann, A; Schuligoi, R Laropiprant Attenuates EP3 and TP Prostanoid Receptor-Mediated Thrombus Formation.
PLoS One. 2012; 7(8):e40222-e40222 Doi: 10.1371/journal.pone.0040222 [OPEN ACCESS]
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Schröder, R; Xue, L; Konya, V; Martini, L; Kampitsch, N; Whistler, JL; Ulven, T; Heinemann, A; Pettipher, R; Kostenis, E PGH1, the precursor for the anti-inflammatory prostaglandins of the 1-series, is a potent activator of the pro-inflammatory receptor CRTH2/DP2.
PLoS One. 2012; 7(3):e33329-e33329 Doi: 10.1371/journal.pone.0033329 [OPEN ACCESS]
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Bernini, F; Costet, P; Ehrenborg, E; Fisher, R; Fielding, B; Freeman, D; Groen, A; Malle, E; Mulder, M; Niemeier, A; Hansen, AT; von Eckardstein, A European Lipoprotein Club: Report of the 34th ELC annual conference, Tutzing, 5-8 September 2011.
Atherosclerosis. 2012; 221(1):287-293 Doi: 10.1016/j.atherosclerosis.2011.12.002
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Brkić, L; Riederer, M; Graier, WF; Malli, R; Frank, S Acyl chain-dependent effect of lysophosphatidylcholine on cyclooxygenase (COX)-2 expression in endothelial cells.
Atherosclerosis. 2012; 224(2):348-354 Doi: 10.1016/j.atherosclerosis.2012.07.038 [OPEN ACCESS]
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Jaffer, I; Riederer, M; Shah, P; Peters, P; Quehenberger, F; Wood, A; Scharnagl, H; März, W; Kostner, KM; Kostner, GM Expression of fat mobilizing genes in human epicardial adipose tissue.
Atherosclerosis. 2012; 220(1): 122-127. Doi: 10.1016/j.atherosclerosis.2011.10.026
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Trbušić, M; Riederer, M; Vučić, M; Lovričević, I; Krušlin, B; Gauster, M; Mohrenz, S; Berghold, A; Tiran, B; Degoricija, V; Frank, S Increased expression of endothelial lipase in symptomatic and unstable carotid plaques.
J Neurol. 2012; 259(3):448-456 Doi: 10.1007/s00415-011-6198-3 [OPEN ACCESS]
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Leis, HJ; Windischhofer, W; Determination of memantine in human plasma by GC using negative ion chemical ionization MS detection after derivatization with a new reagent.
MICROCHIM ACTA. 2012; 178(3-4): 309-314. Doi: 10.1007/s00604-012-0840-3
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Leis, HJ; Windischhofer, W; Quantitative determination of memantine in human plasma by GC using negative ion chemical ionization MS detection after derivatization with a new reagent, o-(pentafluorobenzyloxycarbonyl)-2,3,4,5-tetrafluorobenzoyl chloride.
MICROCHIM ACTA. 2012; 179(3-4): 249-255. Doi: 10.1007/s00604-012-0886-2
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Adlbrecht, C; Aigner, E; Bellón, JM; Bouloukaki, I; Bouzas-Mosquera, A; Carrilho, AJ; Chang, KC; Chattipakorn, N; Chattipakorn, SC; Chen, YJ; Chung, YC; Colah, R; Datz, C; Frøkjaer, JB; Fujimori, S; Georgiadou, P; Grion, CM; Hsu, CP; Hülsmann, M; Hung, MJ; Hung, MY; Iliodromitis, EK; Lang, IM; Lee, TI; März, W; Nair, SB; Pascual, G; Peteiro, J; Sakamoto, C; Satomura, A; Schiza, SE; Stärkel, P; Stojakovic, T; Vesely, DL; Walters, DL; Yilmaz, Y Research update for articles published in EJCI in 2010.
Eur J Clin Invest. 2012; 42(11): 1149-1164. Doi: 10.1111/eci.12001
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Birner-Gruenberger, R; Bickmeyer, I; Lange, J; Hehlert, P; Hermetter, A; Kollroser, M; Rechberger, GN; Kühnlein, RP Functional fat body proteomics and gene targeting reveal in vivo functions of Drosophila melanogaster á-Esterase-7.
Insect Biochem Mol Biol. 2012; 42(3): 220-229. Doi: 10.1016/j.ibmb.2011.12.004 [OPEN ACCESS]
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Windischhofer, W; Huber, E; Rossmann, C; Semlitsch, M; Kitz, K; Rauh, A; Devaney, T; Leis, HJ; Malle, E LPA-induced suppression of periostin in human osteosarcoma cells is mediated by the LPA(1)/Egr-1 axis.
Biochimie. 2012; 94(9):1997-2005 Doi: 10.1016/j.biochi.2012.05.023 [OPEN ACCESS]
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Acharya, G; Albrecht, C; Benton, SJ; Cotechini, T; Dechend, R; Dilworth, MR; Duttaroy, AK; Grotmol, T; Heazell, AE; Jansson, T; Johnstone, ED; Jones, HN; Jones, RL; Lager, S; Laine, K; Nagirnaja, L; Nystad, M; Powell, T; Redman, C; Sadovsky, Y; Sibley, C; Troisi, R; Wadsack, C; Westwood, M; Lash, GE IFPA Meeting 2011 workshop report I: Placenta: Predicting future health; roles of lipids in the growth and development of feto-placental unit; placental nutrient sensing; placental research to solve clinical problems--a translational approach.
Placenta. 2012; 33 Suppl(3):S4-S8 Doi: 10.1016/j.placenta.2011.11.015
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Piao, G; Saito, S; Sun, Y; Liu, ZP; Wang, Y; Han, X; Wu, J; Zhou, H; Chen, L; Horimoto, K A computational procedure for identifying master regulator candidates: a case study on diabetes progression in Goto-Kakizaki rats.
BMC Syst Biol. 2012; 6 Suppl 1(5): S2-S2. Doi: 10.1186/1752-0509-6-S1-S2 [OPEN ACCESS]
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Viertler, M; Schittmayer, M; Birner-Gruenberger, R Activity based subcellular resolution imaging of lipases.
Bioorg Med Chem. 2012; 20(2):628-632 Doi: 10.1016/j.bmc.2011.04.018
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Falkensammer, J; Gasteiger, S; Stojakovic, T; Stühlinger, M; Scharnagl, H; Frech, A; Fraedrich, G; Greiner, A; Huber, K Elevated baseline hs-cTnT levels predict exercise-induced myocardial ischemia in patients with peripheral arterial disease.
Clin Chim Acta. 2012; 413(19-20):1678-1682 Doi: 10.1016/j.cca.2012.05.014
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Peterbauer-Scherb, A; Danzer, M; Gabriel, C; van Griensven, M; Redl, H; Wolbank, S In vitro adipogenesis of adipose-derived stem cells in 3D fibrin matrix of low component concentration.
J Tissue Eng Regen Med. 2012; 6(6): 434-442. Doi: 10.1002/term.446
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Radovic, B; Aflaki, E; Kratky, D Adipose triglyceride lipase in immune response, inflammation, and atherosclerosis.
Biol Chem. 2012; 393(9):1005-1011 Doi: 10.1515/hsz-2012-0192 [OPEN ACCESS]
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Graulich, T; Das, SK; Krasteva, G; Ruppert, C; Wessels, L; Hoefler, G; Mühlfeld, C Cancer cachexia alters intracellular surfactant metabolism but not total alveolar surface area.
Histochem Cell Biol. 2012; 138(5):803-813 Doi: 10.1007/s00418-012-0995-3
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Lassance, L; Miedl, H; Konya, V; Heinemann, A; Ebner, B; Hackl, H; Desoye, G; Hiden, U Differential response of arterial and venous endothelial cells to extracellular matrix is modulated by oxygen.
Histochem Cell Biol. 2012; 137(5):641-655 Doi: 10.1007/s00418-012-0917-4
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Leis, HJ; Windischhofer, W Quantitative determination of amphetamine in plasma using negative ion chemical ionization GC-MS of o-(pentafluorobenzyl-oxycarbonyl)-2,3,4,5-tetrafluorobenzoyl derivatives.
J Sep Sci. 2012; 35(23):3326-3331 Doi: 10.1002/jssc.201200579
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Leis, HJ; Windischhofer, W Quantitative method for determination of amphetamine in plasma using negative ion chemical ionisation GC-MS of o-(pentafluorobenzyloxycarbonyl)-benzoyl derivatives.
J Sep Sci. 2012; 35(16):2095-2100 Doi: 10.1002/jssc.201200082
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Leis, HJ; Windischhofer, W (S)-(-)-N-(pentafluorobenzylcarbamoyl)prolyl chloride: a chiral derivatisation reagent designed for gas chromatography/negative ion chemical ionisation mass spectrometry of amino compounds.
Rapid Commun Mass Spectrom. 2012; 26(6):592-598 Doi: 10.1002/rcm.6146
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Stemmer, U; Dunai, ZA; Koller, D; Pürstinger, G; Zenzmaier, E; Deigner, HP; Aflaki, E; Kratky, D; Hermetter, A Toxicity of oxidized phospholipids in cultured macrophages.
Lipids Health Dis. 2012; 11(12):110-110 Doi: 10.1186/1476-511X-11-110 [OPEN ACCESS]
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Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Silbert, D; Gustafsson, U; Sahlin, S; Trauner, M Combined rifampicin and ursodeoxycholic acid treatment does not amplify rifampicin effects on hepatic detoxification and transport systems in humans.
Digestion. 2012; 86(3):244-249 Doi: 10.1159/000341420
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Elkin, RG; Bauer, R; Schneider, WJ The restricted ovulator chicken strain: an oviparous vertebrate model of reproductive dysfunction caused by a gene defect affecting an oocyte-specific receptor.
Anim Reprod Sci. 2012; 136(1-2):1-13 Doi: 10.1016/j.anireprosci.2012.10.002 [OPEN ACCESS]
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Schicho, R; Storr, M Topical and systemic cannabidiol improves trinitrobenzene sulfonic acid colitis in mice.
Pharmacology. 2012; 89(3-4):149-155 Doi: 10.1159/000336871 [OPEN ACCESS]
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Cetin, I; Parisi, F; Berti, C; Mandò, C; Desoye, G Placental fatty acid transport in maternal obesity.
J Dev Orig Health Dis. 2012; 3(6):409-414 Doi: 10.1017/S2040174412000414
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Oberbach, A; von Bergen, M; Bluher, S; Lehmann, S; Till, H; Combined Serum Proteomic and Metabonomic Profiling After Laparoscopic Sleeve Gastrectomy in Children and Adolescents.
J Laparoendosc Adv Surg Tech A. 2012; 22(2):184-188 Doi: 10.1089/lap.2011.0115
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Hissa, DC; Bezerra, GA; Obrist, B; Birner-Grünberger, R; Melo, VM; Gruber, K Crystallization and preliminary X-ray diffraction of the surfactant protein Lv-ranaspumin from the frog Leptodactylus vastus.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012; 68(Pt 3):321-323 Doi: 10.1107/S1744309112002679 [OPEN ACCESS]
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Burian, B; Ortner, A; Prassl, R; Zimmer, A; Mosgoeller, W Clinical potential of VIP by modified pharmaco-kinetics and delivery mechanisms.
Endocr Metab Immune Disord Drug Targets. 2012; 12(4):344-350 Doi: 10.2174/187153012803832594
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Hofmann, NA; Reinisch, A; Strunk, D Endothelial colony-forming progenitor cell isolation and expansion.
Methods Mol Biol. 2012; 879(4):381-387 Doi: 10.1007/978-1-61779-815-3_23
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Riederer, M; Trbušić, M; Degoricija, V; Frank, S Endothelial Lipase Plasma Levels are Increased in Patients With Significant Carotid Artery Stenosis and History of Neurological Impairment.
J Clin Med Res. 2012; 4(1):49-51 Doi: 10.4021/jocmr734w [OPEN ACCESS]
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Wadsack, C; Desoye, G; Hiden, U The feto-placental endothelium in pregnancy pathologies.
Wien Med Wochenschr. 2012; 162(9-10):220-224 Doi: 10.1007/s10354-012-0075-2
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2011

Das, SK; Eder, S; Schauer, S; Diwoky, C; Temmel, H; Guertl, B; Gorkiewicz, G; Tamilarasan, KP; Kumari, P; Trauner, M; Zimmermann, R; Vesely, P; Haemmerle, G; Zechner, R; Hoefler, G Adipose triglyceride lipase contributes to cancer-associated cachexia.
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Haemmerle, G; Moustafa, T; Woelkart, G; Büttner, S; Schmidt, A; van, de, Weijer, T; Hesselink, M; Jaeger, D; Kienesberger, PC; Zierler, K; Schreiber, R; Eichmann, T; Kolb, D; Kotzbeck, P; Schweiger, M; Kumari, M; Eder, S; Schoiswohl, G; Wongsiriroj, N; Pollak, NM; Radner, FP; Preiss-Landl, K; Kolbe, T; Rülicke, T; Pieske, B; Trauner, M; Lass, A; Zimmermann, R; Hoefler, G; Cinti, S; Kershaw, EE; Schrauwen, P; Madeo, F; Mayer, B; Zechner, R ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.
Nat Med. 2011; 17(9):1076-85 Doi: 10.1038/nm.2439 [OPEN ACCESS]
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Chennamsetty, I; Claudel, T; Kostner, KM; Baghdasaryan, A; Kratky, D; Levak-Frank, S; Frank, S; Gonzalez, FJ; Trauner, M; Kostner, GM Farnesoid X receptor represses hepatic human APOA gene expression.
J Clin Invest. 2011; 121(9):3724-3734 Doi: 10.1172/JCI45277 [OPEN ACCESS]
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Mahajan, V; Klingstedt, T; Simon, R; Nilsson, KP; Thueringer, A; Kashofer, K; Haybaeck, J; Denk, H; Abuja, PM; Zatloukal, K Cross β-sheet conformation of keratin 8 is a specific feature of Mallory-Denk bodies compared with other hepatocyte inclusions.
Gastroenterology. 2011; 141(3):1080-1090.e1-1080-1090.e7 Doi: 10.1053/j.gastro.2011.05.039
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Mueller, KM; Kornfeld, JW; Friedbichler, K; Blaas, L; Egger, G; Esterbauer, H; Hasselblatt, P; Schlederer, M; Haindl, S; Wagner, KU; Engblom, D; Haemmerle, G; Kratky, D; Sexl, V; Kenner, L; Kozlov, AV; Terracciano, L; Zechner, R; Schuetz, G; Casanova, E; Pospisilik, JA; Heim, MH; Moriggl, R Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice.
Hepatology. 2011; 54(4):1398-1409 Doi: 10.1002/hep.24509 [OPEN ACCESS]
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Holzer, M; Birner-Gruenberger, R; Stojakovic, T; El-Gamal, D; Binder, V; Wadsack, C; Heinemann, A; Marsche, G Uremia Alters HDL Composition and Function.
J Am Soc Nephrol. 2011; 22(9):1631-1641 Doi: 10.1681/ASN.2010111144 [OPEN ACCESS]
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Kratky, D Neutral cholesterol ester hydrolases in macrophages: still a matter of debate.
CIRC RES. 2011; 108(10): e13-e13. Doi: 10.1161/CIRCRESAHA.111.245829 [OPEN ACCESS]
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Holzer, M; Gauster, M; Pfeifer, T; Wadsack, C; Fauler, G; Stiegler, P; Koefeler, H; Beubler, E; Schuligoi, R; Heinemann, A; Marsche, G Protein carbamylation renders high-density lipoprotein dysfunctional.
Antioxid Redox Signal. 2011; 14(12): 2337-2346. Doi: 10.1089/ars.2010.3640 [OPEN ACCESS]
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Gauster, M; Hiden, U; Vanpoppel, M; Frank, S; Wadsack, C; Hauguel-de Mouzon, S; Desoye, G Dysregulation of placental endothelial lipase in obese women with gestational diabetes mellitus.
Diabetes. 2011; 60(10): 2457-2464. Doi: 10.2337/db10-1434 [OPEN ACCESS]
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Balenga, NA; Aflaki, E; Kargl, J; Platzer, W; Schröder, R; Blättermann, S; Kostenis, E; Brown, AJ; Heinemann, A; Waldhoer, M GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils.
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Nucleic Acids Res. 2011; 39(8): 3224-3239. Doi: 10.1093/nar/gkq1289 [OPEN ACCESS]
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Desoye, G; Gauster, M; Wadsack, C Placental transport in pregnancy pathologies.
Am J Clin Nutr. 2011; 94(6 Suppl):1896S-11902 Doi: 10.3945/ajcn.110.000851 [OPEN ACCESS]
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Aflaki, E; Balenga, NA; Luschnig-Schratl, P; Wolinski, H; Povoden, S; Chandak, PG; Bogner-Strauss, JG; Eder, S; Konya, V; Kohlwein, SD; Heinemann, A; Kratky, D Impaired Rho GTPase activation abrogates cell polarization and migration in macrophages with defective lipolysis.
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Arterioscler Thromb Vasc Biol. 2011; 31(9):2080-2089 Doi: 10.1161/ATVBAHA.111.231431 [OPEN ACCESS]
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Lammers, B; Chandak, PG; Aflaki, E; Van Puijvelde, GH; Radovic, B; Hildebrand, RB; Meurs, I; Out, R; Kuiper, J; Van Berkel, TJ; Kolb, D; Haemmerle, G; Zechner, R; Levak-Frank, S; Van Eck, M; Kratky, D Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice.
Arterioscler Thromb Vasc Biol. 2011; 31(1): 67-73. Doi: 10.1161/ATVBAHA.110.215814 [OPEN ACCESS]
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Wolinski, H; Kolb, D; Hermann, S; Koning, RI; Kohlwein, SD A role for seipin in lipid droplet dynamics and inheritance in yeast.
J Cell Sci. 2011; 124(Pt 22): 3894-3904. Doi: 10.1242/jcs.091454 [OPEN ACCESS]
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Dichlberger, A; Schlager, S; Lappalainen, J; Käkelä, R; Hattula, K; Butcher, SJ; Schneider, WJ; Kovanen, PT Lipid body formation during maturation of human mast cells.
J Lipid Res. 2011; 52(12):2198-2208 Doi: 10.1194/jlr.M019737 [OPEN ACCESS]
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Fauland, A; Köfeler, H; Trötzmüller, M; Knopf, A; Hartler, J; Eberl, A; Chitraju, C; Lankmayr, E; Spener, F A comprehensive method for lipid profiling by liquid chromatography-ion cyclotron resonance mass spectrometry.
J Lipid Res. 2011; 52(12):2314-2322 Doi: 10.1194/jlr.D016550 [OPEN ACCESS]
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Földes-Papp, Z; Liao, SC; Barbieri, B; Gryczynski, K; Luchowski, R; Gryczynski, Z; Gryczynski, I; Borejdo, J; You, T Single actomyosin motor interactions in skeletal muscle.
Biochim Biophys Acta. 2011; 1813(5):858-866 Doi: 10.1016/j.bbamcr.2011.02.001 [OPEN ACCESS]
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Hartler, J; Trötzmüller, M; Chitraju, C; Spener, F; Köfeler, HC; Thallinger, GG Lipid Data Analyzer: unattended identification and quantitation of lipids in LC-MS data.
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Free Radic Biol Med. 2011; 50(7):854-865 Doi: 10.1016/j.freeradbiomed.2010.12.039
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Chandak, PG; Obrowsky, S; Radovic, B; Doddapattar, P; Aflaki, E; Kratzer, A; Doshi, LS; Povoden, S; Ahammer, H; Hoefler, G; Levak-Frank, S; Kratky, D Lack of acyl-CoA:diacylglycerol acyltransferase 1 reduces intestinal cholesterol absorption and attenuates atherosclerosis in apolipoprotein E knockout mice.
Biochim Biophys Acta. 2011; 1811(12): 1011-1020. Doi: 10.1016/j.bbalip.2011.08.010 [OPEN ACCESS]
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Grillitsch, K; Connerth, M; Köfeler, H; Arrey, TN; Rietschel, B; Wagner, B; Karas, M; Daum, G Lipid particles/droplets of the yeast Saccharomyces cerevisiae revisited: lipidome meets proteome.
Biochim Biophys Acta. 2011; 1811(12):1165-1176 Doi: 10.1016/j.bbalip.2011.07.015 [OPEN ACCESS]
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Horvath, SE; Wagner, A; Steyrer, E; Daum, G Metabolic link between phosphatidylethanolamine and triacylglycerol metabolism in the yeast Saccharomyces cerevisiae.
Biochim Biophys Acta. 2011; 1811(12): 1030-1037. Doi: 10.1016/j.bbalip.2011.08.007 [OPEN ACCESS]
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März, W; Genser, B; Drechsler, C; Krane, V; Grammer, TB; Ritz, E; Stojakovic, T; Scharnagl, H; Winkler, K; Holme, I; Holdaas, H; Wanner, C; German Diabetes and Dialysis Study Investigators Atorvastatin and low-density lipoprotein cholesterol in type 2 diabetes mellitus patients on hemodialysis.
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Grunert, T; Leitner, NR; Marchetti-Deschmann, M; Miller, I; Wallner, B; Radwan, M; Vogl, C; Kolbe, T; Kratky, D; Gemeiner, M; Allmaier, G; Müller, M; Strobl, B A comparative proteome analysis links tyrosine kinase 2 (Tyk2) to the regulation of cellular glucose and lipid metabolism in response to poly(I:C).
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Schicho, R; Bashashati, M; Bawa, M; McHugh, D; Saur, D; Hu, HM; Zimmer, A; Lutz, B; Mackie, K; Bradshaw, HB; McCafferty, DM; Sharkey, KA; Storr, M The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment.
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Patankar, JV; Chandak, PG; Obrowsky, S; Pfeifer, T; Diwoky, C; Uellen, A; Sattler, W; Stollberger, R; Hoefler, G; Heinemann, A; Battle, M; Duncan, S; Kratky, D; Levak-Frank, S Loss of intestinal GATA4 prevents diet-induced obesity and promotes insulin sensitivity in mice.
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Henstridge, CM; Balenga, NA; Kargl, J; Andradas, C; Brown, AJ; Irving, A; Sanchez, C; Waldhoer, M Minireview: recent developments in the physiology and pathology of the lysophosphatidylinositol-sensitive receptor GPR55.
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Chen, F; Zhu, Y; Tang, X; Sun, Y; Jia, W; Sun, Y; Han, X Dynamic regulation of PDX-1 and FoxO1 expression by FoxA2 in dexamethasone-induced pancreatic β-cells dysfunction.
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Liu, Z; Segawa, H; Aydin, C; Reyes, M; Erben, RG; Weinstein, LS; Chen, M; Marshansky, V; Fröhlich, LF; Bastepe, M Transgenic overexpression of the extra-large Gsα variant XLαs enhances Gsα-mediated responses in the mouse renal proximal tubule in vivo.
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Zhang, Y; Lei, T; Huang, JF; Wang, SB; Zhou, LL; Yang, ZQ; Chen, XD The link between fibroblast growth factor 21 and sterol regulatory element binding protein 1c during lipogenesis in hepatocytes.
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Semlitsch, M; Shackelford, RE; Zirkl, S; Sattler, W; Malle, E ATM protects against oxidative stress induced by oxidized low-density lipoprotein.
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Poparic, I; Schreibmayer, W; Schoser, B; Desoye, G; Gorischek, A; Miedl, H; Hochmeister, S; Binder, J; Quasthoff, S; Wagner, K; Windpassinger, C; Malle, E Four and a half LIM protein 1C (FHL1C): a binding partner for voltage-gated potassium channel K(v1.5).
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Etschmaier, K; Becker, T; Eichmann, TO; Schweinzer, C; Scholler, M; Tam-Amersdorfer, C; Poeckl, M; Schuligoi, R; Kober, A; Chirackal, Manavalan, AP; Rechberger, GN; Streith, IE; Zechner, R; Zimmermann, R; Panzenboeck, U Adipose triglyceride lipase affects triacylglycerol metabolism at brain barriers.
J Neurochem. 2011; 119(5):1016-28 Doi: 10.1111/j.1471-4159.2011.07498.x [OPEN ACCESS]
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Strunk, D Endothelial progenitor cells: quod erat demonstrandum?
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Bernini, F; Fisher, R; Freeman, D; Groen, A; Kalopissis, A; Malle, E; Mulder, M; Niemeier, A; Parini, P; Hansen, AT; von Eckardstein, A Report of the 33rd annual conference of the European Lipoprotein Club, Tutzing, 6-9 September 2010.
Atherosclerosis. 2011; 215(1): 249-255. Doi: 10.1016/j.atherosclerosis.2010.12.002
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Riederer, M; Lechleitner, M; Hrzenjak, A; Koefeler, H; Desoye, G; Heinemann, A; Frank, S Endothelial lipase (EL) and EL-generated lysophosphatidylcholines promote IL-8 expression in endothelial cells.
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Leis, HJ; Schütz, H; Windischhofer, W Quantitative determination of methylphenidate in plasma by gas chromatography negative ion chemical ionisation mass spectrometry using o-(pentafluorobenzyloxycarbonyl)-benzoyl derivatives.
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Leis, HJ; Windischhofer, W A versatile electrophoric derivatisation reagent for negative ion chemical ionisation mass spectrometry: o-(pentafluorobenzyloxycarbonyl)-2,3,4,5-tetrafluorobenzoyl chloride.
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Schweinzer, C; Kober, A; Lang, I; Etschmaier, K; Scholler, M; Kresse, A; Sattler, W; Panzenboeck, U Processing of endogenous AβPP in blood-brain barrier endothelial cells is modulated by liver-X receptor agonists and altered cellular cholesterol homeostasis.
J Alzheimers Dis. 2011; 27(2):341-360 Doi: 10.3233/JAD-2011-110854
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Nikitina, L; Wenger, F; Baumann, M; Surbek, D; Körner, M; Albrecht, C Expression and localization pattern of ABCA1 in diverse human placental primary cells and tissues.
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Zou, W; Roth, RA; Younis, HS; Malle, E; Ganey, PE Neutrophil-cytokine interactions in a rat model of sulindac-induced idiosyncratic liver injury.
TOXICOLOGY. 2011; 290(2-3): 278-285. Doi: 10.1016/j.tox.2011.10.005 [OPEN ACCESS]
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Rohde, E; Schallmoser, K; Reinisch, A; Hofmann, NA; Pfeifer, T; Fröhlich, E; Rechberger, G; Lanzer, G; Kratky, D; Strunk, D Pro-angiogenic induction of myeloid cells for therapeutic angiogenesis can induce mitogen-activated protein kinase p38-dependent foam cell formation.
Cytotherapy. 2011; 13(4):503-512 Doi: 10.3109/14653249.2010.536214 [OPEN ACCESS]
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Gruber-Wackernagel, A; Heinemann, A; Konya, V; Byrne, SN; Singh, TP; Hofer, A; Legat, F; Wolf, P Photohardening restores the impaired neutrophil responsiveness to chemoattractants leukotriene B4 and formyl-methionyl-leucyl-phenylalanin in patients with polymorphic light eruption.
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Sourij, H; Schmoelzer, I; de Campo, A; Tripolt, NJ; Stojakovic, T; Scharnagl, H; Kettler-Schmut, E; Forst, T; Wascher, TC Non-glycemic effects of insulin therapy: a comparison between insulin aspart and regular human insulin during two consecutive meals in patients with type 2 diabetes.
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Trötzmüller, M; Guo, X; Fauland, A; Köfeler, H; Lankmayr, E Characteristics and origins of common chemical noise ions in negative ESI LC-MS.
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Rossmann, C; Rauh, A; Hammer, A; Windischhofer, W; Zirkl, S; Sattler, W; Malle, E Hypochlorite-modified high-density lipoprotein promotes induction of HO-1 in endothelial cells via activation of p42/44 MAPK and zinc finger transcription factor Egr-1.
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Földes-Papp, Z; Baumann, G Fluorescence molecule counting for single-molecule studies in crowded environment of living cells without and with broken ergodicity.
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Augsten, M; Hackl, H; Ebner, B; Chemelli, A; Glatter, O; Marsche, G; Lang, U; Desoye, G; Wadsack, C Fetal HDL/apoE: a novel regulator of gene expression in human placental endothelial cells.
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Resch, U; Semlitsch, M; Hammer, A; Susani-Etzerodt, H; Walczak, H; Sattler, W; Malle, E Hypochlorite-modified low-density lipoprotein induces the apoptotic machinery in Jurkat T-cell lines.
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Riegler, B; Besenboeck, C; Bauer, R; Nimpf, J; Schneider, WJ Enzymes involved in hepatic acylglycerol metabolism in the chicken.
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Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Lackner, C; Thorell, A; Trauner, M Ursodeoxycholic acid for treatment of fatty liver disease and dyslipidemia in morbidly obese patients.
Dig Dis. 2011; 29(1):117-118 Doi: 10.1159/000324146
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Mundigler, G; Gaggl, M; Heinze, G; Graf, S; Zehetgruber, M; Lajic, N; Voigtländer, T; Mannhalter, C; Sunder-Plassmann, R; Paschke, E; Fauler, G; Sunder-Plassmann, G The endocardial binary appearance ('binary sign') is an unreliable marker for echocardiographic detection of Fabry disease in patients with left ventricular hypertrophy.
Eur J Echocardiogr. 2011; 12(10):744-749 Doi: 10.1093/ejechocard/jer112 [OPEN ACCESS]
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Rozsasi, A; Heinemann, A; Keck, T Cyclooxygenase 2 and lipoxin A₄ in nasal polyps in cystic fibrosis.
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Raspotnig, G; Leutgeb, V; Krisper, G; Leis, HJ Discrimination of Oribotritia species by oil gland chemistry (Acari, Oribatida).
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Stradner, MH; Angerer, H; Ortner, T; Fuerst, FC; Setznagl, D; Kremser, ML; Hermann, J; Graninger, WB The immunosuppressant FTY720 (fingolimod) enhances glycosaminoglycan depletion in articular cartilage.
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Wiltgen, M; Tilz, GP Molecular diagnosis and prognosis with DNA microarrays.
Hematology. 2011; 16(3):166-176 Doi: 10.1179/102453311X12953015767257
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Schicho, R; Storr, M Alternative targets within the endocannabinoid system for future treatment of gastrointestinal diseases.
CAN J GASTROENTEROL. 2011; 25(7): 377-383. Doi: 10.1155/2011/953975 [OPEN ACCESS]
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Genser, B; Dias, KC; Siekmeier, R; Stojakovic, T; Grammer, T; Maerz, W Lipoprotein (a) and risk of cardiovascular disease--a systematic review and meta analysis of prospective studies.
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Hakim-Weber, R; Krogsdam, AM; Jørgensen, C; Fischer, M; Prokesch, A; Bogner-Strauss, JG; Bornstein, SR; Hansen, JB; Madsen, L; Kristiansen, K; Trajanoski, Z; Hackl, H Transcriptional regulatory program in wild-type and retinoblastoma gene-deficient mouse embryonic fibroblasts during adipocyte differentiation.
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Molnar, A; Haybaeck, J; Lackner, C; Strnad, P The cytoskeleton in nonalcoholic steatohepatitis: 100 years old but still youthful.
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Tancevski, I; Demetz, E; Eller, P Sobetirome: a selective thyromimetic for the treatment of dyslipidemia.
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2010

Ritsch, A; Scharnagl, H; Eller, P; Tancevski, I; Duwensee, K; Demetz, E; Sandhofer, A; Boehm, BO; Winkelmann, BR; Patsch, JR; März, W Cholesteryl ester transfer protein and mortality in patients undergoing coronary angiography: the Ludwigshafen Risk and Cardiovascular Health study.
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Hepatology. 2010; 51(4):1319-1326 Doi: 10.1002/hep.23469 [OPEN ACCESS]
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Fröhlich, LF; Mrakovcic, M; Steinborn, R; Chung, UI; Bastepe, M; Jüppner, H Targeted deletion of the Nesp55 DMR defines another Gnas imprinting control region and provides a mouse model of autosomal dominant PHP-Ib.
Proc Natl Acad Sci U S A. 2010; 107(20): 9275-9280. Doi: 10.1073/pnas.0910224107 [OPEN ACCESS]
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Karpen, SJ; Trauner, M The new therapeutic frontier--nuclear receptors and the liver.
J Hepatol. 2010; 52(3):455-462 Doi: 10.1016/j.jhep.2009.12.002
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Konya, V; Sturm, EM; Schratl, P; Beubler, E; Marsche, G; Schuligoi, R; Lippe, IT; Peskar, BA; Heinemann, A Endothelium-derived prostaglandin I(2) controls the migration of eosinophils.
J Allergy Clin Immunol. 2010; 125(5): 1105-1113. Doi: 10.1016/j.jaci.2009.12.002
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Philipose, S; Konya, V; Sreckovic, I; Marsche, G; Lippe, IT; Peskar, BA; Heinemann, A; Schuligoi, R The Prostaglandin E2 Receptor EP4 Is Expressed by Human Platelets and Potently Inhibits Platelet Aggregation and Thrombus Formation.
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Cell Mol Life Sci. 2010; 67(23): 4049-4064. Doi: 10.1007/s00018-010-0424-5
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van Rijn, RM; Whistler, JL; Waldhoer, M Opioid-receptor-heteromer-specific trafficking and pharmacology.
Curr Opin Pharmacol. 2010; 10(1): 73-79. Doi: 10.1016/j.coph.2009.09.007 [OPEN ACCESS]
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Blouin, CM; Le Lay, S; Eberl, A; Koefeler, HC; Guerrera, IC; Klein, C; Le Liepvre, X; Lasnier, F; Bourron, O; Gautier, JF; Ferre, P; Hajduch, E; Dugail, I Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects.
J Lipid Res. 2010; 51(5): 945-956. Doi: 10.1194/jlr.M001016 [OPEN ACCESS]
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Buchebner, M; Pfeifer, T; Rathke, N; Chandak, PG; Lass, A; Schreiber, R; Kratzer, A; Zimmermann, R; Sattler, W; Koefeler, H; Froehlich, E; Kostner, GM; Birner-Gruenberger, R; Chiang, KP; Haemmerle, G; Zechner, R; Levak-Frank, S; Cravatt, BF; Kratky, D Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363.
J Lipid Res. 2010; 51(10): 2896-2908. Doi: 10.1194/jlr.M004259 [OPEN ACCESS]
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Riederer, M; Ojala, PJ; Hrzenjak, A; Graier, WF; Malli, R; Tritscher, M; Hermansson, M; Watzer, B; Schweer, H; Desoye, G; Heinemann, A; Frank, S Acyl chain-dependent effect of lysophosphatidylcholine on endothelial prostacyclin production.
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Ullen, A; Fauler, G; Köfeler, H; Waltl, S; Nusshold, C; Bernhart, E; Reicher, H; Leis, HJ; Wintersperger, A; Malle, E; Sattler, W Mouse brain plasmalogens are targets for hypochlorous acid-mediated modification in vitro and in vivo.
Free Radic Biol Med. 2010; 49(11):1655-1665 Doi: 10.1016/j.freeradbiomed.2010.08.025 [OPEN ACCESS]
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Schicher, M; Morak, M; Birner-Gruenberger, R; Kayer, H; Stojcic, B; Rechberger, GN; Kollroser, M; Hermetter, A Functional proteomic analysis of lipases and esterases in cultured human adipocytes.
J Proteome Res. 2010; 9(12): 6334-6344. Doi: 10.1021/pr1005795
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Chandak, PG; Radovic, B; Aflaki, E; Kolb, D; Buchebner, M; Fröhlich, E; Magnes, C; Sinner, F; Haemmerle, G; Zechner, R; Tabas, I; Levak-Frank, S; Kratky, D Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase.
J Biol Chem. 2010; 285(26):20192-20201 Doi: 10.1074/jbc.M110.107854 [OPEN ACCESS]
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Connerth, M; Czabany, T; Wagner, A; Zellnig, G; Leitner, E; Steyrer, E; Daum, G Oleate inhibits steryl ester synthesis and causes liposensitivity in yeast.
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Gruber, A; Cornaciu, I; Lass, A; Schweiger, M; Poeschl, M; Eder, C; Kumari, M; Schoiswohl, G; Wolinski, H; Kohlwein, SD; Zechner, R; Zimmermann, R; Oberer, M The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase.
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Radner, FP; Streith, IE; Schoiswohl, G; Schweiger, M; Kumari, M; Eichmann, TO; Rechberger, G; Koefeler, HC; Eder, S; Schauer, S; Theussl, HC; Preiss-Landl, K; Lass, A; Zimmermann, R; Hoefler, G; Zechner, R; Haemmerle, G Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58).
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Trauner, M; Arrese, M; Wagner, M Fatty liver and lipotoxicity.
Biochim Biophys Acta. 2010; 1801(3): 299-310. Doi: 10.1016/j.bbalip.2009.10.007 [OPEN ACCESS]
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Henstridge, CM; Balenga, NAB; Schroder, R; Kargl, JK; Platzer, W; Martini, L; Arthur, S; Penman, J; Whistler, JL; Kostenis, E; Waldhoer, M; Irving, AJ GPR55 ligands promote receptor coupling to multiple signalling pathways.
BRIT J PHARMACOL. 2010; 160(3): 604-614. Doi: 10.1111/j.1476-5381.2009.00625.x [OPEN ACCESS]
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Mullen, PJ; Lüscher, B; Scharnagl, H; Krähenbühl, S; Brecht, K Effect of simvastatin on cholesterol metabolism in C2C12 myotubes and HepG2 cells, and consequences for statin-induced myopathy.
Biochem Pharmacol. 2010; 79(8): 1200-1209. Doi: 10.1016/j.bcp.2009.12.007
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J Chromatogr A. 2010; 1217(50):7826-7832 Doi: 10.1016/j.chroma.2010.10.062
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Stojakovic, T; Claudel, T; Putz-Bankuti, C; Fauler, G; Scharnagl, H; Wagner, M; Sourij, H; Stauber, RE; Winkler, K; März, W; Wascher, TC; Trauner, M Low-dose atorvastatin improves dyslipidemia and vascular function in patients with primary biliary cirrhosis after one year of treatment.
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Stojakovic, T; Scharnagl, H; Trauner, M; Pieske, B; Wellnitz, B; Seelhorst, U; Schilling, D; Winkelmann, BR; Boehm, BO; März, W Serum gamma-glutamyl transferase and mortality in persons undergoing coronary angiography-The Ludwigshafen Risk and Cardiovascular Health Study.
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Anal Bioanal Chem. 2010; 396(7): 2629-2637. Doi: 10.1007/s00216-010-3479-0
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Bodlaj, G; Hubmann, R; Pichler, R; Saleh, K; Stojakovic, T; Biesenbach, G; Berg, J Thyroid hormones in molecular adsorbent recirculating system-treated patients with Child C cirrhosis: a case series.
LIVER INT. 2010; 30(6): 927-928. Doi: 10.1111/j.1478-3231.2010.02237.x
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Baumann, G; Gryczynski, I; Földes-Papp, Z Anomalous behavior in length distributions of 3D random Brownian walks and measured photon count rates within observation volumes of single-molecule trajectories in fluorescence fluctuation microscopy.
Opt Express. 2010; 18(17):17883-17896 Doi: 10.1364/OE.18.017883 [OPEN ACCESS]
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Luchowski, R; Gryczynski, Z; Foldes-Papp, Z; Chang, A; Borejdo, J; Sarkar, P; Gryczynski, I Polarized fluorescent nanospheres.
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Köfeler, HC; Tiboldi, A; Hoeger, H; Lubec, G Hippocampal lipids linked to spatial memory in the C57bl/6j mouse.
Neurochem Int. 2010; 57(8): 935-939. Doi: 10.1016/j.neuint.2010.09.013
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Baumann, G; Place, RF; Földes-Papp, Z Meaningful interpretation of subdiffusive measurements in living cells (crowded environment) by fluorescence fluctuation microscopy.
Curr Pharm Biotechnol. 2010; 11(5):527-543 Doi: 10.2174/138920110791591454 [OPEN ACCESS]
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Földes-Papp, Z; Liao, SC; You, T; Terpetschnig, E; Barbieri, B Confocal fluctuation spectroscopy and imaging.
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Neri, M; Bello, S; Bonsignore, A; Centini, F; Fiore, C; Földes-Papp, Z; Turillazzi, E; Fineschi, V Myocardial expression of TNF-alpha, IL-1beta, IL-6, IL-8, IL-10 and MCP-1 after a single MDMA dose administered in a rat model.
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Place, RF; Noonan, EJ; Földes-Papp, Z; Li, LC Defining features and exploring chemical modifications to manipulate RNAa activity.
Curr Pharm Biotechnol. 2010; 11(5):518-526 Doi: 10.2174/138920110791591463 [OPEN ACCESS]
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Rees, MD; Whitelock, JM; Malle, E; Chuang, CY; Iozzo, RV; Nilasaroya, A; Davies, MJ Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan.
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Hofer, D; Paul, K; Fantur, K; Beck, M; Roubergue, A; Vellodi, A; Poorthuis, BJ; Michelakakis, H; Plecko, B; Paschke, E Phenotype determining alleles in GM1 gangliosidosis patients bearing novel GLB1 mutations.
Clin Genet. 2010; 78(3):236-246 Doi: 10.1111/j.1399-0004.2010.01379.x
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Bordag, N; Keller, S Alpha-helical transmembrane peptides: a "divide and conquer" approach to membrane proteins.
Chem Phys Lipids. 2010; 163(1):1-26 Doi: 10.1016/j.chemphyslip.2009.07.009
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Leis, HJ; Windischhofer, W o-(Pentafluorobenzyloxycarbonyl)benzoyl chloride: a novel electrophoric derivatisation reagent for amino compounds designed for negative ion chemical ionisation mass spectrometry.
Rapid Commun Mass Spectrom. 2010; 24(22): 3320-3324. Doi: 10.1002/rcm.4775
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Anderwald, C; Ankersmit, HJ; Badaoui, A; Beneduce, L; Buko, VU; Calo, LA; Carrero, JJ; Chang, CY; Chang, KC; Chen, YJ; Cnotliwy, M; Costelli, P; Crujeiras, AB; Cuocolo, A; Davis, PA; de Boer, OJ; Ebenbichler, CF; Erridge, C; Fassina, G; Felix, SB; Garcia-Gomez, MC; Guerrero-Romero, F; Haider, DG; Heinemann, A; Herda, LR; Hoogeveen, EK; Horl, WH; Iglseder, B; Huang, KC; Kaser, S; Kastrati, A; Kuzniatsova, N; Latella, G; Lichtenauer, M; Lin, YK; Lip, GYH; Lu, NH; Lukivskaya, O; Luschnig, P; Maniscalco, M; Martinez, JA; Muller-Krebs, S; Ndrepepa, G; Nicolaou, G; Peck-Radosavljevic, M; Penna, F; Pinto, X; Reiberger, T; Rodriguez-Moran, M; Schmidt, A; Schwenger, V; Spinelli, L; Starkel, P; Stehouwer, CDA; Stenvinkel, P; Strasser, P; Suzuki, H; Tschoner, A; van der Wal, AC; Vesely, DL; Wen, CJ; Wiernicki, I; Zanninelli, G; Zhu, Y Research update for articles published in EJCI in 2008
EUR J CLIN INVEST. 2010; 40(9): 770-789. Doi: 10.1111/j.1365-2362.2010.02351.x
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Duwensee, K; Breitling, LP; Tancevski, I; Rothenbacher, D; Demetz, E; Patsch, JR; Ritsch, A; Eller, P; Brenner, H Cholesteryl ester transfer protein in patients with coronary heart disease.
Eur J Clin Invest. 2010; 40(7):616-622 Doi: 10.1111/j.1365-2362.2010.02313.x
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Stojakovic, T; de Campo, A; Scharnagl, H; Sourij, H; Schmölzer, I; Wascher, TC; März, W Differential effects of fluvastatin alone or in combination with ezetimibe on lipoprotein subfractions in patients at high risk of coronary events.
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Huang, J; Zhang, J; Lei, T; Chen, X; Zhang, Y; Zhou, L; Yu, A; Chen, Z; Zhou, R; Yang, Z Cloning of porcine chemerin, ChemR23 and GPR1 and their involvement in regulation of lipogenesis.
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Sturm, EM; Kranzelbinder, B; Heinemann, A; Groselj-Strele, A; Aberer, W; Sturm, GJ CD203c-based basophil activation test in allergy diagnosis: Characteristics and differences to CD63 upregulation.
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Lex, A; Streit, M; Partl, C; Kashofer, K; Schmalstieg, D Comparative analysis of multidimensional, quantitative data.
IEEE TRANS VISUAL COMPUT GR. 2010; 16(6): 1027-1035. Doi: 10.1109/TVCG.2010.138
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Schuligoi, R; Sturm, E; Luschnig, P; Konya, V; Philipose, S; Sedej, M; Waldhoer, M; Peskar, BA; Heinemann, A CRTH2 and D-type prostanoid receptor antagonists as novel therapeutic agents for inflammatory diseases.
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Zhang, J; Lei, T; Chen, X; Peng, Y; Long, H; Zhou, L; Huang, J; Chen, Z; Long, Q; Yang, Z Resistin up-regulates COX-2 expression via TAK1-IKK-NF-kappaB signaling pathway.
Inflammation. 2010; 33(1): 25-33. Doi: 10.1007/s10753-009-9155-x
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Oettl, K; Marsche, G Redox State of Human Serum Albumin in Terms of Cysteine-34 in Health and Disease.
Methods Enzymol. 2010; 474C: 181-195. Doi: 10.1016/S0076-6879(10)74011-8
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Hipmair, G; Böhler, N; Maschek, W; Soriguer, F; Rojo-Martínez, G; Schimetta, W; Pichler, R Serum leptin is correlated to high turnover in osteoporosis.
Neuro Endocrinol Lett. 2010; 31(1):155-160
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Tannapfel, A; Denk, H; Dienes, HP; Langner, C; Schirmacher, P; Trauner, M; Flott-Rahmel, B Histopathological diagnose of non-alcoholic and alcoholic fatty liver disease.
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Tannapfel, A; Denk, H; Dienes, HP; Langner, C; Schirmacher, P; Trauner, M; Flott-Rahmel, B Histopathological diagnosis of non-alcoholic and alcoholic fatty liver disease. Grade 2 consensus-based guidelines.
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LaboratoriumsMedizin / Journal of Laboratory Medicine. 2010; 34(4): 217-222. Doi: 10.1515/JLM.2010.040
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2009

Ferré, S; Baler, R; Bouvier, M; Caron, MG; Devi, LA; Durroux, T; Fuxe, K; George, SR; Javitch, JA; Lohse, MJ; Mackie, K; Milligan, G; Pfleger, KD; Pin, JP; Volkow, ND; Waldhoer, M; Woods, AS; Franco, R Building a new conceptual framework for receptor heteromers.
Nat Chem Biol. 2009; 5(3): 131-134. Doi: 10.1038/nchembio0309-131 [OPEN ACCESS]
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Fickert, P; Fuchsbichler, A; Wagner, M; Silbert, D; Zatloukal, K; Denk, H; Trauner, M The role of the hepatocyte cytokeratin network in bile formation and resistance to bile acid challenge and cholestasis in mice.
Hepatology. 2009; 50(3):893-899 Doi: 10.1002/hep.23068 [OPEN ACCESS]
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Halilbasic, E; Fiorotto, R; Fickert, P; Marschall, HU; Moustafa, T; Spirli, C; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Langner, C; Maitra, U; Denk, H; Hofmann, AF; Strazzabosco, M; Trauner, M Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice.
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Wagner, M; Zollner, G; Trauner, M New molecular insights into the mechanisms of cholestasis.
J Hepatol. 2009; 51(3): 565-580. Doi: 10.1016/j.jhep.2009.05.012 [OPEN ACCESS]
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Vesely, PW; Staber, PB; Hoefler, G; Kenner, L Translational regulation mechanisms of AP-1 proteins.
Mutat Res. 2009; 682(1):7-12 Doi: 10.1016/j.mrrev.2009.01.001
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Hofer, D; Paul, K; Fantur, K; Beck, M; Burger, F; Caillaud, C; Fumic, K; Ledvinova, J; Lugowska, A; Michelakakis, H; Radeva, B; Ramaswami, U; Plecko, B; Paschke, E GM1 Gangliosidosis and Morquio B Disease: Expression Analysis of Missense Mutations Affecting the Catalytic Site of Acid beta-Galactosidase
HUM MUTAT. 2009; 30(8): 1214-1221. Doi: 10.1002/humu.21031
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Graier, WF; Malli, R; Kostner, GM Mitochondrial protein phosphorylation: instigator or target of lipotoxicity?
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Malle, E; Sodin-Semrl, S; Kovacevic, A Serum amyloid A: an acute-phase protein involved in tumour pathogenesis.
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Chemistry. 2009; 15(37): 9521-9529. Doi: 10.1002/chem.200900915
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Kienesberger, PC; Lee, D; Pulinilkunnil, T; Brenner, DS; Cai, L; Magnes, C; Koefeler, HC; Streith, IE; Rechberger, GN; Haemmerle, G; Flier, JS; Zechner, R; Kim, YB; Kershaw, EE Adipose Triglyceride Lipase Deficiency Causes Tissue-specific Changes in Insulin Signaling.
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Petschnigg, J; Wolinski, H; Kolb, D; Zellnig, G; Kurat, CF; Natter, K; Kohlwein, SD Good fat, essential cellular requirements for triacylglycerol synthesis to maintain membrane homeostasis in yeast.
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Zollner, G; Trauner, M Nuclear receptors as therapeutic targets in cholestatic liver diseases.
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Kostner, KM; Kostner, GM Fibrate in lipid metabolism disorders
Pharm Unserer Zeit. 2007; 36(2): 114-119. Doi: 10.1002/pauz.200600209
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2006

Haemmerle, G; Lass, A; Zimmermann, R; Gorkiewicz, G; Meyer, C; Rozman, J; Heldmaier, G; Maier, R; Theussl, C; Eder, S; Kratky, D; Wagner, EF; Klingenspor, M; Hoefler, G; Zechner, R Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase.
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Lass, A; Zimmermann, R; Haemmerle, G; Riederer, M; Schoiswohl, G; Schweiger, M; Kienesberger, P; Strauss, JG; Gorkiewicz, G; Zechner, R Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome.
Cell Metab. 2006; 3(5):309-319 Doi: 10.1016/j.cmet.2006.03.005 [OPEN ACCESS]
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Fickert, P; Wagner, M; Marschall, HU; Fuchsbichler, A; Zollner, G; Tsybrovskyy, O; Zatloukal, K; Liu, J; Waalkes, MP; Cover, C; Denk, H; Hofmann, AF; Jaeschke, H; Trauner, M 24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
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Marschall, HU; Trauner, M Complementary stimulation of hepatobiliary transport and detoxification by rifampicin and ursodeoxycholic acid in humans - Reply
GASTROENTEROLOGY. 2006; 130: 620-620. Doi: 10.1053/j.gastro.2006.01.019
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Rust, C; Bauchmuller, K; Bernt, C; Vennegeerts, T; Fickert, P; Fuchsbichler, A; Beuers, U Sulfasalazine reduces bile acid induced apoptosis in human hepatoma cells and perfused rat livers.
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Meisner, F; Walcher, D; Gizard, F; Kapfer, X; Huber, R; Noak, A; Sunder-Plassmann, L; Bach, H; Haug, C; Bachem, M; Stojakovic, T; März, W; Hombach, V; Koenig, W; Staels, B; Marx, N Effect of rosiglitazone treatment on plaque inflammation and collagen content in nondiabetic patients: data from a randomized placebo-controlled trial.
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Ellis, E; Wagner, M; Lammert, F; Nemeth, A; Gumhold, J; Strassburg, CP; Kylander, C; Katsika, D; Trauner, M; Einarsson, C; Marschall, HU Successful treatment of severe unconjugated hyperbilirubinemia via induction of UGT1A1 by rifampicin.
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Fickert, P; Fuchsbichler, A; Marschall, HU; Wagner, M; Zollner, G; Krause, R; Zatloukal, K; Jaeschke, H; Denk, H; Trauner, M Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice.
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Pilz, S; Scharnagl, H; Tiran, B; Seelhorst, U; Wellnitz, B; Boehm, BO; Schaefer, JR; März, W Free fatty acids are independently associated with all-cause and cardiovascular mortality in subjects with coronary artery disease.
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Schmidt, R; Schmidt, H; Pichler, M; Enzinger, C; Petrovic, K; Niederkorn, K; Horner, S; Ropele, S; Watzinger, N; Schumacher, M; Berghold, A; Kostner, GM; Fazekas, F C-reactive protein, carotid atherosclerosis, and cerebral small-vessel disease: results of the Austrian Stroke Prevention Study.
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Panzenboeck, U; Kratzer, I; Sovic, A; Wintersperger, A; Bernhart, E; Hammer, A; Malle, E; Sattler, W Regulatory effects of synthetic liver X receptor- and peroxisome-proliferator activated receptor agonists on sterol transport pathways in polarized cerebrovascular endothelial cells.
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Schratl, P; Sturm, EM; Royer, JF; Sturm, GJ; Lippe, IT; Peskar, BA; Heinemann, A Hierarchy of eosinophil chemoattractants: role of p38 mitogen-activated protein kinase.
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Marschall, HU; Wagner, M; Bodin, K; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Sjövall, J; Trauner, M Fxr(-/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids.
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Graziani, A; Rosker, C; Kohlwein, SD; Zhu, MX; Romanin, C; Sattler, W; Groschner, K; Poteser, M Cellular cholesterol controls TRPC3 function: evidence from a novel dominant-negative knockdown strategy.
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Grill, M; Peskar, BA; Schuligoi, R; Amann, R Systemic inflammation induces COX-2 mediated prostaglandin D2 biosynthesis in mice spinal cord.
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Hörl, G; Kroisel, PM; Wagner, E; Tiran, B; Petek, E; Steyrer, E Compound heterozygosity (G71R/R140H) in the lecithin:cholesterol acyltransferase (LCAT) gene results in an intermediate phenotype between LCAT-deficiency and fish-eye disease.
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Idzior-Walus, B; Sieradzki, J; Kostner, G; Malecki, MT; Klupa, T; Wesolowska, T; Rostworowski, W; Hartwich, J; Walus, M; Kiec, AD; Naruszewicz, M Familial lecithin-cholesterol acyltransferase deficiency: biochemical characteristics and molecular analysis of a new LCAT mutation in a Polish family.
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Boyer, JL; Trauner, M; Mennone, A; Soroka, CJ; Cai, SY; Moustafa, T; Zollner, G; Lee, JY; Ballatori, N Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents.
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Malle, E; Marsche, G; Arnhold, J; Davies, MJ Modification of low-density lipoprotein by myeloperoxidase-derived oxidants and reagent hypochlorous acid.
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Resch, U; Tatzber, F; Budinsky, A; Sinzinger, H Reduction of oxidative stress and modulation of autoantibodies against modified low-density lipoprotein after rosuvastatin therapy.
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Geier, A; Fickert, P; Trauner, M Mechanisms of disease: mechanisms and clinical implications of cholestasis in sepsis.
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Susani-Etzerodt, H; Schmidinger, H; Riesenhuber, G; Birner-Gruenberger, R; Hermetter, A A versatile library of activity-based probes for fluorescence detection and/or affinity isolation of lipolytic enzymes.
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Griesbacher, T; Rainer, I; Heinemann, A; Groisman, D Haemodynamic and exocrine effects of caerulein at submaximal and supramaximal levels on the rat pancreas: role of cholecystokinin receptor subtypes.
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Sundl, I; Pail, E; Mellitzer, K; Toplak, H; Winklhofer-Roob, BM Effects of orlistat therapy on plasma concentrations of oxygenated and hydrocarbon carotenoids
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Fischer, R; Schütz, H; Grossmann, M; Leis, HJ; Ammer, R Bioequivalence of a methylphenidate hydrochloride extended-release preparation: comparison of an intact capsule and an opened capsule sprinkled on applesauce.
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Gurakuqi, GC; Stadlbauer, V; Stepan, V; Warnkross, H; Trauner, M Addison's disease as a rare cause of chronically elevated liver enzymes].
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Putz-Bankuti, C; Datz, C; März, W; Lackner, C; Stauber, RE; Trauner, M; Toplak, H; Stojakovic, T; Krejs, GJ Clinical-pathological conference series from the Medical University of Graz : case no. 131: elevated transaminases in a 30-year-old male.
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Stark, K; Eder, J; Zatloukal, K Priority-based k-anonymity accomplished by weighted generalisation structures
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Bondarenko, OI; Sahach, VF The role of Na+,K+ ATPase in electrogenicity of the aortic endothelial cells.
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Zollner, G; Trauner, M Molecular mechanisms of cholestasis.
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2005

Kratky, D; Zimmermann, R; Wagner, EM; Strauss, JG; Jin, W; Kostner, GM; Haemmerle, G; Rader, DJ; Zechner, R Endothelial lipase provides an alternative pathway for FFA uptake in lipoprotein lipase-deficient mouse adipose tissue.
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Winkler, K; Winkelmann, BR; Scharnagl, H; Hoffmann, MM; Grawitz, AB; Nauck, M; Böhm, BO; März, W Platelet-activating factor acetylhydrolase activity indicates angiographic coronary artery disease independently of systemic inflammation and other risk factors: the Ludwigshafen Risk and Cardiovascular Health Study.
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Waldhoer, M; Fong, J; Jones, RM; Lunzer, MM; Sharma, SK; Kostenis, E; Portoghese, PS; Whistler, JL A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers.
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Leis, HJ; Windischhofer, W Quantitative determination of fluvastatin in human plasma by gas chromatography/negative ion chemical ionization mass spectrometry using 18O2-fluvastatin as an internal standard.
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Raspotnig, G; Fauler, G; Leis, M; Leis, HJ Chemical profiles of scent gland secretions in the cyphophthalmid opilionid harvestmen, Siro duricorius and S-exilis
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Zollner, G; Wagner, M; Fickert, P; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Hepatobiliary transporter expression in human hepatocellular carcinoma.
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Bondarenko, OI; Sahach, VF Attenuation of acetylcholine-induced hyperpolarization of aortic endothelial cells in rats fed by high-salt diet and its correction with enalapril.
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Domej, W; Schwaberger, G; Guger, C; Herfert, J; Haditsch, B; Földes-Papp, Z; Tilz, GP Aspects and necessity of moderate-altitude research
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Stadlbauer, V; Fickert, P; Lackner, C; Schmerlaib, J; Krisper, P; Trauner, M; Stauber, RE Hepatotoxicity of NONI juice: report of two cases.
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Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Kaser, A; Tilg, H; Krause, R; Lammert, F; Langner, C; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
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März, W; Scharnagl, H; Winkler, K; Tiran, A; Nauck, M; Boehm, BO; Winkelmann, BR Low-density lipoprotein triglycerides associated with low-grade systemic inflammation, adhesion molecules, and angiographic coronary artery disease: the Ludwigshafen Risk and Cardiovascular Health study.
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Müller, T; Langner, C; Fuchsbichler, A; Heinz-Erian, P; Ellemunter, H; Schlenck, B; Bavdekar, AR; Pradhan, AM; Pandit, A; Müller-Höcker, J; Melter, M; Kobayashi, K; Nagasaka, H; Kikuta, H; Müller, W; Tanner, MS; Sternlieb, I; Zatloukal, K; Denk, H Immunohistochemical analysis of Mallory bodies in Wilsonian and non-Wilsonian hepatic copper toxicosis.
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